IMP
Process View
negative regulation of systemic arterial blood pressure
The process that reduces the force with which blood travels through the systemic arterial circulatory system.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of systemic arterial blood pressure"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.846 | ||
| BMP2 | bone morphogenetic protein 2 | 0.794 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.772 | ||
| SMAD2 | SMAD family member 2 | 0.767 | ||
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.718 | ||
| GDF5 | growth differentiation factor 5 | 0.551 | ||
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.468 | ||
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 0.344 | ||
| BBS2 | Bardet-Biedl syndrome 2 | 0.325 | ||
| ACVR1 | activin A receptor, type I | 0.285 | Human | |
| TGFB3 | transforming growth factor, beta 3 | 0.273 | ||
| SMAD7 | SMAD family member 7 | 0.269 | ||
| IL8 | interleukin 8 | 0.201 | ||
| FSTL1 | follistatin-like 1 | 0.187 | ||
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.163 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.149 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.143 | ||
| NRP1 | neuropilin 1 | 0.139 | ||
| ARRDC3 | arrestin domain containing 3 | 0.132 | ||
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.116 | ||
| SCNN1B | sodium channel, nonvoltage-gated 1, beta | 0.112 | ||
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.109 | ||
| BBS9 | Bardet-Biedl syndrome 9 | 0.104 | ||
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.103 | Human | |
| PRNP | prion protein | 0.102 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.096 | Human | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.076 | ||
| TKT | transketolase | 0.066 | ||
| PCM1 | pericentriolar material 1 | 0.063 | ||
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.054 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.054 | ||
| HSPB1 | heat shock 27kDa protein 1 | 0.053 | ||
| DUSP6 | dual specificity phosphatase 6 | 0.053 | ||
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.052 | ||
| WNK1 | WNK lysine deficient protein kinase 1 | 0.050 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.048 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.048 | ||
| RXRA | retinoid X receptor, alpha | 0.044 | ||
| ARNT | aryl hydrocarbon receptor nuclear translocator | 0.044 | ||
| NAMPT | nicotinamide phosphoribosyltransferase | 0.044 | ||
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.043 | ||
| EXOC7 | exocyst complex component 7 | 0.043 | ||
| BBS1 | Bardet-Biedl syndrome 1 | 0.041 | ||
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.039 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.036 | ||
| E2F2 | E2F transcription factor 2 | 0.035 | ||
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.033 | ||
| VEGFA | vascular endothelial growth factor A | 0.033 | ||
| ENG | endoglin | 0.030 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.030 | ||
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.028 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.026 | ||
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.024 | Mouse | |
| CUX1 | cut-like homeobox 1 | 0.022 | ||
| ANTXR2 | anthrax toxin receptor 2 | 0.022 | ||
| FNDC3B | fibronectin type III domain containing 3B | 0.022 | ||
| PGD | phosphogluconate dehydrogenase | 0.022 | ||
| UPP1 | uridine phosphorylase 1 | 0.022 | ||
| TTC8 | tetratricopeptide repeat domain 8 | 0.021 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.021 | ||
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.020 | ||
| ARL6 | ADP-ribosylation factor-like 6 | 0.020 | ||
| TGFBR3 | transforming growth factor, beta receptor III | 0.020 | ||
| BMP4 | bone morphogenetic protein 4 | 0.019 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.019 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.018 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.018 | ||
| NCOA6 | nuclear receptor coactivator 6 | 0.017 | ||
| ACVR1B | activin A receptor, type IB | 0.017 | Human | |
| PDGFC | platelet derived growth factor C | 0.016 | ||
| IL1B | interleukin 1, beta | 0.016 | ||
| PURA | purine-rich element binding protein A | 0.016 | ||
| ALDOB | aldolase B, fructose-bisphosphate | 0.016 | ||
| USP15 | ubiquitin specific peptidase 15 | 0.016 | ||
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.016 | ||
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | 0.015 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.015 | ||
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.015 | ||
| SRGN | serglycin | 0.014 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.014 | ||
| PAX2 | paired box 2 | 0.013 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.013 | ||
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.013 | ||
| HSCB | HscB iron-sulfur cluster co-chaperone homolog (E. coli) | 0.013 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.013 | ||
| SRI | sorcin | 0.013 | ||
| PRMT2 | protein arginine methyltransferase 2 | 0.012 | ||
| DOCK8 | dedicator of cytokinesis 8 | 0.012 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.012 | ||
| BBS7 | Bardet-Biedl syndrome 7 | 0.012 | ||
| FTL | ferritin, light polypeptide | 0.012 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.012 | ||
| TALDO1 | transaldolase 1 | 0.012 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.012 | ||
| GATAD2B | GATA zinc finger domain containing 2B | 0.012 | ||
| NDFIP2 | Nedd4 family interacting protein 2 | 0.011 | ||
| IL6R | interleukin 6 receptor | 0.011 | ||
| TSHR | thyroid stimulating hormone receptor | 0.011 | ||
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.011 | ||
| IL1R1 | interleukin 1 receptor, type I | 0.011 | ||
| ARF3 | ADP-ribosylation factor 3 | 0.011 | ||
| ZNHIT6 | zinc finger, HIT-type containing 6 | 0.011 | ||
| GLA | galactosidase, alpha | 0.011 | ||
| ACVR2A | activin A receptor, type IIA | 0.011 | ||
| THBS1 | thrombospondin 1 | 0.011 | ||
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.011 | ||
| FTH1 | ferritin, heavy polypeptide 1 | 0.011 | ||
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.011 | ||
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.011 | ||
| GK | glycerol kinase | 0.010 | ||
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.010 | ||
| PTEN | phosphatase and tensin homolog | 0.010 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.010 | ||
| FRK | fyn-related kinase | 0.010 | ||
| BBS12 | Bardet-Biedl syndrome 12 | 0.010 | ||
| MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.010 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.010 | ||
| JAG1 | jagged 1 | 0.010 | ||
| PLK3 | polo-like kinase 3 | 0.010 |