IMP

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Homo sapiens

3 genes annotated in human

Multi-species View

glomerular mesangial cell proliferation

GO:0072110

The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glomerular mesangial cell proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glomerular mesangial cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	1.000
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	1.000
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.999
NRP1	neuropilin 1	0.998
VEGFA	vascular endothelial growth factor A	0.997	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.987	Mouse
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.939
BMPR1A	bone morphogenetic protein receptor, type IA	0.921
PDGFA	platelet-derived growth factor alpha polypeptide	0.863	Human
PLCG1	phospholipase C, gamma 1	0.754
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.686
PGF	placental growth factor	0.634	Human
FSTL1	follistatin-like 1	0.606
CAV1	caveolin 1, caveolae protein, 22kDa	0.605
BMPR1B	bone morphogenetic protein receptor, type IB	0.544
COL6A1	collagen, type VI, alpha 1	0.445
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.395
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.302
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.266
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.266
COL2A1	collagen, type II, alpha 1	0.258
NOG	noggin	0.236
PDGFC	platelet derived growth factor C	0.214
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.173
COL4A1	collagen, type IV, alpha 1	0.156
COL5A1	collagen, type V, alpha 1	0.151
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.127
COL1A1	collagen, type I, alpha 1	0.125
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.107
IER2	immediate early response 2	0.095
SNAI1	snail homolog 1 (Drosophila)	0.089
PTPRB	protein tyrosine phosphatase, receptor type, B	0.087
EGR3	early growth response 3	0.085
EGR2	early growth response 2	0.080
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.078
BMP4	bone morphogenetic protein 4	0.071
STC1	stanniocalcin 1	0.067
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.064
SLA	Src-like-adaptor	0.062
BMP2	bone morphogenetic protein 2	0.055	Human
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.050
BHLHE40	basic helix-loop-helix family, member e40	0.049
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.043
DDIT3	DNA-damage-inducible transcript 3	0.041
DDIT4	DNA-damage-inducible transcript 4	0.041
MDFI	MyoD family inhibitor	0.038
COL1A2	collagen, type I, alpha 2	0.037
PTEN	phosphatase and tensin homolog	0.035
COL6A2	collagen, type VI, alpha 2	0.032
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.032
JUNB	jun B proto-oncogene	0.030
TGFB2	transforming growth factor, beta 2	0.029
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.024
FST	follistatin	0.023
FZD4	frizzled homolog 4 (Drosophila)	0.021
LDLR	low density lipoprotein receptor	0.021
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.020
NFIL3	nuclear factor, interleukin 3 regulated	0.020
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.020
NRP2	neuropilin 2	0.020
TAOK1	TAO kinase 1	0.020
TBX2	T-box 2	0.019
IGFBP5	insulin-like growth factor binding protein 5	0.019
CDH5	cadherin 5, type 2 (vascular endothelium)	0.019
WNT2	wingless-type MMTV integration site family member 2	0.018
ZNF205	zinc finger protein 205	0.018
FLT4	fms-related tyrosine kinase 4	0.018
FOXF1	forkhead box F1	0.018
HSPG2	heparan sulfate proteoglycan 2	0.018
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.018
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.018
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.017
COL3A1	collagen, type III, alpha 1	0.017
ZFYVE9	zinc finger, FYVE domain containing 9	0.017
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.017
LOXL2	lysyl oxidase-like 2	0.016
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.016
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.016
INHBB	inhibin, beta B	0.016
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.016
BMP8B	bone morphogenetic protein 8b	0.016	Human
BMP6	bone morphogenetic protein 6	0.016	Human
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.016
FYB	FYN binding protein	0.016
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.015
G0S2	G0/G1switch 2	0.015
COL4A2	collagen, type IV, alpha 2	0.015
EPAS1	endothelial PAS domain protein 1	0.015
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.015
GAS1	growth arrest-specific 1	0.014
STC2	stanniocalcin 2	0.014
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.014
NCK2	NCK adaptor protein 2	0.014
CD248	CD248 molecule, endosialin	0.013
WISP2	WNT1 inducible signaling pathway protein 2	0.013
ANGPT2	angiopoietin 2	0.013
FZD10	frizzled homolog 10 (Drosophila)	0.013
TRIB1	tribbles homolog 1 (Drosophila)	0.013
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.013
NPM3	nucleophosmin/nucleoplasmin 3	0.013
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.013
TWIST1	twist homolog 1 (Drosophila)	0.013
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.013
HAND1	heart and neural crest derivatives expressed 1	0.012
TEK	TEK tyrosine kinase, endothelial	0.012
EFNB3	ephrin-B3	0.012
JAG1	jagged 1	0.012
FOXF2	forkhead box F2	0.012
BMP3	bone morphogenetic protein 3	0.012	Human
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.011
JUND	jun D proto-oncogene	0.011
MMP19	matrix metallopeptidase 19	0.011
ACAN	aggrecan	0.011
SOD3	superoxide dismutase 3, extracellular	0.011
PITX2	paired-like homeodomain 2	0.011
VLDLR	very low density lipoprotein receptor	0.011
TGFB3	transforming growth factor, beta 3	0.011
CER1	cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)	0.011
EDN1	endothelin 1	0.011
F3	coagulation factor III (thromboplastin, tissue factor)	0.011
THBS1	thrombospondin 1	0.011
COL13A1	collagen, type XIII, alpha 1	0.010
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.010
FZD2	frizzled homolog 2 (Drosophila)	0.010
COL16A1	collagen, type XVI, alpha 1	0.010
NDRG1	N-myc downstream regulated 1	0.010
TGFB1	transforming growth factor, beta 1	0.010
FGFR1	fibroblast growth factor receptor 1	0.010