IMP

Process View

Homo sapiens

1 genes annotated in human

chemokine c c motif ligand 19 signaling pathway

A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chemokine c c motif ligand 19 signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "chemokine c c motif ligand 19 signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
CCL5	chemokine (C-C motif) ligand 5	1.000
CCR5	chemokine (C-C motif) receptor 5	1.000	Human
IL2RB	interleukin 2 receptor, beta	0.995
IFNG	interferon, gamma	0.990
CXCR6	chemokine (C-X-C motif) receptor 6	0.986	Human
CCR2	chemokine (C-C motif) receptor 2	0.975	Human
CD40LG	CD40 ligand	0.933
CXCL9	chemokine (C-X-C motif) ligand 9	0.924
CCL22	chemokine (C-C motif) ligand 22	0.903
CCL4	chemokine (C-C motif) ligand 4	0.899
IRF4	interferon regulatory factor 4	0.893
CCR7	chemokine (C-C motif) receptor 7	0.798
CD2	CD2 molecule	0.743
SLAMF7	SLAM family member 7	0.696
CXCR3	chemokine (C-X-C motif) receptor 3	0.659	Human
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.655
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.548
IL10RA	interleukin 10 receptor, alpha	0.500
CCR4	chemokine (C-C motif) receptor 4	0.488	Human
CXCR4	chemokine (C-X-C motif) receptor 4	0.467	Human
GZMK	granzyme K (granzyme 3; tryptase II)	0.447
ITK	IL2-inducible T-cell kinase	0.394
IL10	interleukin 10	0.367
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.360
CLEC7A	C-type lectin domain family 7, member A	0.356
GPR171	G protein-coupled receptor 171	0.338
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.333
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.328
CXCL13	chemokine (C-X-C motif) ligand 13	0.268
FASLG	Fas ligand (TNF superfamily, member 6)	0.267
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.256
CXCL11	chemokine (C-X-C motif) ligand 11	0.247
CD48	CD48 molecule	0.227
IL2RG	interleukin 2 receptor, gamma	0.217
CCL3	chemokine (C-C motif) ligand 3	0.202
CXCL10	chemokine (C-X-C motif) ligand 10	0.192
IL18RAP	interleukin 18 receptor accessory protein	0.168
CCR6	chemokine (C-C motif) receptor 6	0.154	Human
SIT1	signaling threshold regulating transmembrane adaptor 1	0.149
CCR8	chemokine (C-C motif) receptor 8	0.143	Human
CCR9	chemokine (C-C motif) receptor 9	0.141	Human
IL21R	interleukin 21 receptor	0.130
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.125
CCL19	chemokine (C-C motif) ligand 19	0.121
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.118
GPR18	G protein-coupled receptor 18	0.117
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.106
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.104
SLAMF1	signaling lymphocytic activation molecule family member 1	0.104
CCL11	chemokine (C-C motif) ligand 11	0.103
CCL8	chemokine (C-C motif) ligand 8	0.094
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.088
CCL7	chemokine (C-C motif) ligand 7	0.086
SELL	selectin L	0.084
GIMAP4	GTPase, IMAP family member 4	0.078
CD83	CD83 molecule	0.067
PRF1	perforin 1 (pore forming protein)	0.065
LAG3	lymphocyte-activation gene 3	0.064
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.062
IL7R	interleukin 7 receptor	0.062
IL4	interleukin 4	0.060
IL1F5	interleukin 1 family, member 5 (delta)	0.058
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.058
CD8A	CD8a molecule	0.055
RUNX3	runt-related transcription factor 3	0.055
CXCR2	chemokine (C-X-C motif) receptor 2	0.055	Human
CD160	CD160 molecule	0.054
IL2RA	interleukin 2 receptor, alpha	0.054
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.053
LGALS2	lectin, galactoside-binding, soluble, 2	0.052
PVRIG	poliovirus receptor related immunoglobulin domain containing	0.052
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.051
GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)	0.048
CXCR5	chemokine (C-X-C motif) receptor 5	0.048	Human
CD28	CD28 molecule	0.044
DPP4	dipeptidyl-peptidase 4	0.044
CCR3	chemokine (C-C motif) receptor 3	0.043	Human
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.043
IL1B	interleukin 1, beta	0.040
TBX21	T-box 21	0.039
RGS1	regulator of G-protein signaling 1	0.039
CYBB	cytochrome b-245, beta polypeptide	0.038
TNF	tumor necrosis factor	0.038
SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	0.037
CCL20	chemokine (C-C motif) ligand 20	0.037
TRAT1	T cell receptor associated transmembrane adaptor 1	0.035
SLAMF6	SLAM family member 6	0.034
NKG7	natural killer cell group 7 sequence	0.034
TCL1A	T-cell leukemia/lymphoma 1A	0.034
CCR1	chemokine (C-C motif) receptor 1	0.033	Human
CD3D	CD3d molecule, delta (CD3-TCR complex)	0.033
CD226	CD226 molecule	0.033
CD86	CD86 molecule	0.033
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.032
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.032
UBASH3A	ubiquitin associated and SH3 domain containing A	0.032
CD69	CD69 molecule	0.032
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.031
CLEC4E	C-type lectin domain family 4, member E	0.031
TRAF3IP3	TRAF3 interacting protein 3	0.031
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.030
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.030
IL1R2	interleukin 1 receptor, type II	0.029
LAMP3	lysosomal-associated membrane protein 3	0.029
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.028
BIN2	bridging integrator 2	0.028
ADAMDEC1	ADAM-like, decysin 1	0.028
XCL2	chemokine (C motif) ligand 2	0.028
CD1C	CD1c molecule	0.028
CD6	CD6 molecule	0.026
CD84	CD84 molecule	0.025
IGSF6	immunoglobulin superfamily, member 6	0.025
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.025
IL18R1	interleukin 18 receptor 1	0.024
AQP9	aquaporin 9	0.023
STAT4	signal transducer and activator of transcription 4	0.023
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.023
LY9	lymphocyte antigen 9	0.022
GRAP2	GRB2-related adaptor protein 2	0.022
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.021
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.021
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.021
CD5	CD5 molecule	0.020
ICOS	inducible T-cell co-stimulator	0.020
SASH3	SAM and SH3 domain containing 3	0.020
CXCR1	chemokine (C-X-C motif) receptor 1	0.020	Human
SIRPB1	signal-regulatory protein beta 1	0.020
CYTIP	cytohesin 1 interacting protein	0.019
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.019
CLEC10A	C-type lectin domain family 10, member A	0.019
TLR2	toll-like receptor 2	0.018
SH2D2A	SH2 domain containing 2A	0.018
IL6R	interleukin 6 receptor	0.018
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.018
GPR183	G protein-coupled receptor 183	0.018
KLRG1	killer cell lectin-like receptor subfamily G, member 1	0.018
IDO1	indoleamine 2,3-dioxygenase 1	0.017
FGL2	fibrinogen-like 2	0.017
IL1A	interleukin 1, alpha	0.017
TAGAP	T-cell activation RhoGTPase activating protein	0.017
GPR109B	G protein-coupled receptor 109B	0.017
AOAH	acyloxyacyl hydrolase (neutrophil)	0.017
CD4	CD4 molecule	0.017
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.017
PTAFR	platelet-activating factor receptor	0.016
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.016
CLC	Charcot-Leyden crystal protein	0.016
CCL2	chemokine (C-C motif) ligand 2	0.016
EOMES	eomesodermin	0.016
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.016
GPR65	G protein-coupled receptor 65	0.016
IL8	interleukin 8	0.015
PDCD1LG2	programmed cell death 1 ligand 2	0.015
CD1A	CD1a molecule	0.015
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.015
XCR1	chemokine (C motif) receptor 1	0.015	Human
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.014
LAX1	lymphocyte transmembrane adaptor 1	0.014
TARP	TCR gamma alternate reading frame protein	0.014
GNLY	granulysin	0.014
GZMM	granzyme M (lymphocyte met-ase 1)	0.013
GIMAP5	GTPase, IMAP family member 5	0.013
LAIR2	leukocyte-associated immunoglobulin-like receptor 2	0.013
FFAR2	free fatty acid receptor 2	0.013
C2	complement component 2	0.013
CLEC5A	C-type lectin domain family 5, member A	0.013
CCL13	chemokine (C-C motif) ligand 13	0.013
CRTAM	cytotoxic and regulatory T cell molecule	0.013
IRF8	interferon regulatory factor 8	0.013
EVI2B	ecotropic viral integration site 2B	0.013
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.013
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.013
FPR2	formyl peptide receptor 2	0.012
RSAD2	radical S-adenosyl methionine domain containing 2	0.012
CD27	CD27 molecule	0.012
FAIM3	Fas apoptotic inhibitory molecule 3	0.012
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.012
KRT1	keratin 1	0.012
CD80	CD80 molecule	0.012
CD1E	CD1e molecule	0.011
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.011
CTSW	cathepsin W	0.011
RUNX2	runt-related transcription factor 2	0.011
GPA33	glycoprotein A33 (transmembrane)	0.011
DNASE1L3	deoxyribonuclease I-like 3	0.011
SIRPG	signal-regulatory protein gamma	0.011
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.011
ZBP1	Z-DNA binding protein 1	0.011
NCR3	natural cytotoxicity triggering receptor 3	0.011
IL12RB1	interleukin 12 receptor, beta 1	0.010
EVI2A	ecotropic viral integration site 2A	0.010
IL5RA	interleukin 5 receptor, alpha	0.010
PRDM1	PR domain containing 1, with ZNF domain	0.010