IMP
Process View
lung cell differentiation
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "lung cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TCF4 | transcription factor 4 | 0.512 | ||
| NOTCH1 | notch 1 | 0.502 | ||
| ATXN1L | ataxin 1-like | 0.459 | ||
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.424 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.369 | ||
| NCOA2 | nuclear receptor coactivator 2 | 0.349 | ||
| PGR | progesterone receptor | 0.316 | ||
| CCNE1 | cyclin E1 | 0.291 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.173 | ||
| STK3 | serine/threonine kinase 3 | 0.127 | ||
| AR | androgen receptor | 0.120 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.112 | Mouse | |
| GPSM2 | G-protein signaling modulator 2 | 0.112 | Mouse | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.110 | Mouse | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.101 | ||
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.087 | ||
| QARS | glutaminyl-tRNA synthetase | 0.085 | ||
| ATXN1 | ataxin 1 | 0.074 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.067 | ||
| PSEN1 | presenilin 1 | 0.065 | ||
| BCL6 | B-cell CLL/lymphoma 6 | 0.065 | ||
| SMAD1 | SMAD family member 1 | 0.063 | ||
| NKX3-1 | NK3 homeobox 1 | 0.060 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.055 | ||
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.054 | Mouse | |
| PUM1 | pumilio homolog 1 (Drosophila) | 0.054 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.052 | ||
| STK4 | serine/threonine kinase 4 | 0.050 | ||
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.050 | ||
| MOBKL1A | MOB1, Mps One Binder kinase activator-like 1A (yeast) | 0.049 | ||
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.045 | ||
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.042 | ||
| PAX8 | paired box 8 | 0.040 | ||
| GARS | glycyl-tRNA synthetase | 0.038 | ||
| HDAC5 | histone deacetylase 5 | 0.037 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.036 | ||
| JAG1 | jagged 1 | 0.036 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.034 | ||
| AXIN1 | axin 1 | 0.034 | ||
| LNX1 | ligand of numb-protein X 1 | 0.033 | ||
| NCOA6 | nuclear receptor coactivator 6 | 0.033 | ||
| DARS | aspartyl-tRNA synthetase | 0.032 | ||
| CDC25B | cell division cycle 25 homolog B (S. pombe) | 0.032 | ||
| GLIS2 | GLIS family zinc finger 2 | 0.029 | ||
| NFIA | nuclear factor I/A | 0.027 | ||
| EP300 | E1A binding protein p300 | 0.026 | ||
| HDAC3 | histone deacetylase 3 | 0.026 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.026 | ||
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.026 | ||
| CNO | cappuccino homolog (mouse) | 0.025 | ||
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.024 | ||
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.024 | ||
| RARA | retinoic acid receptor, alpha | 0.023 | ||
| THRA | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 0.023 | Mouse | |
| HDAC10 | histone deacetylase 10 | 0.023 | ||
| HOXA10 | homeobox A10 | 0.022 | ||
| HOXA7 | homeobox A7 | 0.021 | ||
| ONECUT1 | one cut homeobox 1 | 0.021 | ||
| FOXO3 | forkhead box O3 | 0.021 | ||
| JUP | junction plakoglobin | 0.021 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.021 | ||
| HDAC7 | histone deacetylase 7 | 0.021 | ||
| CBX6 | chromobox homolog 6 | 0.021 | ||
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | 0.021 | ||
| CIR1 | corepressor interacting with RBPJ, 1 | 0.020 | ||
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.020 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.020 | ||
| NOTCH2 | notch 2 | 0.020 | ||
| TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) | 0.020 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.020 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.019 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.019 | ||
| KIAA2026 | KIAA2026 | 0.019 | ||
| PKP4 | plakophilin 4 | 0.019 | ||
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.018 | ||
| HOXB5 | homeobox B5 | 0.017 | ||
| TOX4 | TOX high mobility group box family member 4 | 0.017 | ||
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.017 | ||
| FHL2 | four and a half LIM domains 2 | 0.017 | ||
| MOBKL1B | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.016 | ||
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.016 | ||
| AARS | alanyl-tRNA synthetase | 0.016 | ||
| FOXO1 | forkhead box O1 | 0.016 | ||
| FOXJ1 | forkhead box J1 | 0.016 | ||
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 0.015 | ||
| CCNB2 | cyclin B2 | 0.015 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.015 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.015 | ||
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.014 | ||
| FERMT2 | fermitin family member 2 | 0.014 | ||
| FNDC3A | fibronectin type III domain containing 3A | 0.014 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.014 | ||
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.013 | ||
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.013 | ||
| KLF13 | Kruppel-like factor 13 | 0.013 | ||
| XAB2 | XPA binding protein 2 | 0.013 | ||
| TFF3 | trefoil factor 3 (intestinal) | 0.013 | ||
| BTRC | beta-transducin repeat containing | 0.013 | ||
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.013 | ||
| MED1 | mediator complex subunit 1 | 0.013 | ||
| ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.013 | ||
| MED25 | mediator complex subunit 25 | 0.013 | ||
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.013 | ||
| TBL1X | transducin (beta)-like 1X-linked | 0.013 | ||
| HOXA4 | homeobox A4 | 0.013 | ||
| SGSM2 | small G protein signaling modulator 2 | 0.013 | ||
| ZNF395 | zinc finger protein 395 | 0.013 | ||
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.013 | ||
| TSC22D2 | TSC22 domain family, member 2 | 0.013 | ||
| RUNX1 | runt-related transcription factor 1 | 0.012 | ||
| CELF1 | CUGBP, Elav-like family member 1 | 0.012 | ||
| WWTR1 | WW domain containing transcription regulator 1 | 0.012 | ||
| ATF6 | activating transcription factor 6 | 0.012 | ||
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.012 | ||
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.012 | ||
| ACVR1 | activin A receptor, type I | 0.012 | ||
| OTX2 | orthodenticle homeobox 2 | 0.012 | ||
| SCNN1A | sodium channel, nonvoltage-gated 1 alpha | 0.012 | ||
| SNIP1 | Smad nuclear interacting protein 1 | 0.012 | ||
| RXRB | retinoid X receptor, beta | 0.012 | ||
| STON2 | stonin 2 | 0.012 | ||
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.012 | ||
| HOXA1 | homeobox A1 | 0.012 | ||
| SP1 | Sp1 transcription factor | 0.012 | ||
| SEC24D | SEC24 family, member D (S. cerevisiae) | 0.012 | ||
| EPRS | glutamyl-prolyl-tRNA synthetase | 0.012 | ||
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.011 | ||
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.011 | ||
| RXRA | retinoid X receptor, alpha | 0.011 | ||
| C17orf28 | chromosome 17 open reading frame 28 | 0.011 | ||
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.011 | ||
| PROX1 | prospero homeobox 1 | 0.011 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.011 | ||
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.011 | ||
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.011 | ||
| RHOB | ras homolog gene family, member B | 0.011 | ||
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.011 | ||
| BMP2K | BMP2 inducible kinase | 0.011 | ||
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.011 | ||
| C12orf52 | chromosome 12 open reading frame 52 | 0.011 | ||
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.011 | ||
| FAM46A | family with sequence similarity 46, member A | 0.011 | ||
| MLPH | melanophilin | 0.011 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.010 | ||
| CTNNBL1 | catenin, beta like 1 | 0.010 | ||
| MYST3 | MYST histone acetyltransferase (monocytic leukemia) 3 | 0.010 | ||
| HIPK3 | homeodomain interacting protein kinase 3 | 0.010 | ||
| ADAM17 | ADAM metallopeptidase domain 17 | 0.010 | ||
| CHSY1 | chondroitin sulfate synthase 1 | 0.010 | ||
| EEF2K | eukaryotic elongation factor-2 kinase | 0.010 | ||
| TMPRSS2 | transmembrane protease, serine 2 | 0.010 | ||
| APP | amyloid beta (A4) precursor protein | 0.010 |