IMP
Process View
positive regulation of cytokine mediated signaling pathway
Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cytokine mediated signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| GRB2 | growth factor receptor-bound protein 2 | 0.998 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.986 | Human | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.971 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.950 | Human | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.947 | Human | |
| SYK | spleen tyrosine kinase | 0.889 | ||
| HCK | hemopoietic cell kinase | 0.581 | Human | |
| EGFR | epidermal growth factor receptor | 0.529 | ||
| TBK1 | TANK-binding kinase 1 | 0.446 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.400 | ||
| MYD88 | myeloid differentiation primary response gene (88) | 0.369 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.351 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.333 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.296 | ||
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.280 | ||
| GAS6 | growth arrest-specific 6 | 0.263 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.262 | ||
| AXL | AXL receptor tyrosine kinase | 0.255 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.251 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.197 | ||
| TLR4 | toll-like receptor 4 | 0.186 | ||
| NCK1 | NCK adaptor protein 1 | 0.180 | ||
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.179 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.173 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.167 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.139 | ||
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.127 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.113 | ||
| ZNF746 | zinc finger protein 746 | 0.096 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.090 | ||
| SPRR2A | small proline-rich protein 2A | 0.087 | ||
| LAT | linker for activation of T cells | 0.085 | ||
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.078 | Human | |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.072 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.071 | ||
| BLNK | B-cell linker | 0.070 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.068 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.067 | ||
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.062 | ||
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.060 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.057 | Mouse | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.056 | ||
| TRAF3 | TNF receptor-associated factor 3 | 0.055 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.054 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.053 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.047 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.047 | ||
| ITK | IL2-inducible T-cell kinase | 0.046 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.046 | ||
| IL1R1 | interleukin 1 receptor, type I | 0.045 | ||
| TMEM173 | transmembrane protein 173 | 0.039 | ||
| IL1RAP | interleukin 1 receptor accessory protein | 0.037 | ||
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.034 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.033 | ||
| NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.033 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.032 | ||
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.032 | ||
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.030 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.030 | ||
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.028 | Human | |
| FZD1 | frizzled homolog 1 (Drosophila) | 0.025 | ||
| GAS7 | growth arrest-specific 7 | 0.024 | ||
| KLHL24 | kelch-like 24 (Drosophila) | 0.024 | ||
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.023 | ||
| MUC1 | mucin 1, cell surface associated | 0.022 | ||
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.020 | ||
| IRF3 | interferon regulatory factor 3 | 0.020 | Mouse | |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.019 | ||
| TENC1 | tensin like C1 domain containing phosphatase (tensin 2) | 0.019 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.019 | ||
| CD2AP | CD2-associated protein | 0.019 | ||
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.018 | ||
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.018 | ||
| IRS1 | insulin receptor substrate 1 | 0.018 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.018 | ||
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.017 | Human | |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.017 | ||
| PLXNB1 | plexin B1 | 0.017 | ||
| MED28 | mediator complex subunit 28 | 0.015 | ||
| SH2B2 | SH2B adaptor protein 2 | 0.015 | ||
| NELL2 | NEL-like 2 (chicken) | 0.014 | ||
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.014 | ||
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.014 | ||
| FES | feline sarcoma oncogene | 0.013 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.013 | ||
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.012 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.012 | ||
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.012 | ||
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.012 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.012 | ||
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.011 | ||
| PELI3 | pellino homolog 3 (Drosophila) | 0.011 | ||
| JAG2 | jagged 2 | 0.010 | ||
| TNS4 | tensin 4 | 0.010 |