IMP

Process View

Homo sapiens

9 genes annotated in human

positive regulation of granulocyte chemotaxis

Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of granulocyte chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of granulocyte chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	0.999	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.992	Human
CCL5	chemokine (C-C motif) ligand 5	0.965	Human
IL8	interleukin 8	0.809
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.801
S100B	S100 calcium binding protein B	0.776	Human
S100A1	S100 calcium binding protein A1	0.765	Human
CCL4	chemokine (C-C motif) ligand 4	0.760	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.734
CCR7	chemokine (C-C motif) receptor 7	0.691
S100A16	S100 calcium binding protein A16	0.668	Human
S100A14	S100 calcium binding protein A14	0.580
CCL22	chemokine (C-C motif) ligand 22	0.556	Human
CCL2	chemokine (C-C motif) ligand 2	0.405	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.326
S100A6	S100 calcium binding protein A6	0.321
CXCR4	chemokine (C-X-C motif) receptor 4	0.317	Human
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.312
IL6	interleukin 6 (interferon, beta 2)	0.303
CCR4	chemokine (C-C motif) receptor 4	0.291	Human
CCL20	chemokine (C-C motif) ligand 20	0.261	Human
IFNG	interferon, gamma	0.253
CCL8	chemokine (C-C motif) ligand 8	0.225	Human
CCL19	chemokine (C-C motif) ligand 19	0.213
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.194
CCL13	chemokine (C-C motif) ligand 13	0.173	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.166
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.157
CCL3	chemokine (C-C motif) ligand 3	0.152	Human
IL1RN	interleukin 1 receptor antagonist	0.144
CXCL2	chemokine (C-X-C motif) ligand 2	0.142
CCL7	chemokine (C-C motif) ligand 7	0.139	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.136
IL1B	interleukin 1, beta	0.130	Rat
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.122	Human
IL2RB	interleukin 2 receptor, beta	0.120
IL2RG	interleukin 2 receptor, gamma	0.106
CCR1	chemokine (C-C motif) receptor 1	0.105	Human
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.102
TLR4	toll-like receptor 4	0.087
CCR2	chemokine (C-C motif) receptor 2	0.085	Human
IL10	interleukin 10	0.084
PLAUR	plasminogen activator, urokinase receptor	0.082
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.081
IDE	insulin-degrading enzyme	0.071
PLEK	pleckstrin	0.066
CXCL10	chemokine (C-X-C motif) ligand 10	0.058
IRAK2	interleukin-1 receptor-associated kinase 2	0.053
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.050
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.049
SELE	selectin E	0.048
S100A4	S100 calcium binding protein A4	0.047
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.044
S100A9	S100 calcium binding protein A9	0.044
CXCR6	chemokine (C-X-C motif) receptor 6	0.041	Human
IL1R2	interleukin 1 receptor, type II	0.039
CXCL5	chemokine (C-X-C motif) ligand 5	0.039
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.038
CCL11	chemokine (C-C motif) ligand 11	0.035	Human
TNF	tumor necrosis factor	0.035
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.034
IRF4	interferon regulatory factor 4	0.033
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.033	Mouse
CD83	CD83 molecule	0.032
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.031
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.031
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.030
AGER	advanced glycosylation end product-specific receptor	0.029
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.026
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.026
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.025
NCF2	neutrophil cytosolic factor 2	0.025
AREG	amphiregulin	0.024
DPP4	dipeptidyl-peptidase 4	0.024
IRAK4	interleukin-1 receptor-associated kinase 4	0.023
IL18RAP	interleukin 18 receptor accessory protein	0.023
CXCL11	chemokine (C-X-C motif) ligand 11	0.022
S100A8	S100 calcium binding protein A8	0.022
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.022
VCAM1	vascular cell adhesion molecule 1	0.021
SLAMF7	SLAM family member 7	0.021
RGS1	regulator of G-protein signaling 1	0.021
CXCR3	chemokine (C-X-C motif) receptor 3	0.020	Human
ICT1	immature colon carcinoma transcript 1	0.019
CD40LG	CD40 ligand	0.019
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.018
FKBP4	FK506 binding protein 4, 59kDa	0.018
EZR	ezrin	0.017
TLR2	toll-like receptor 2	0.016
S100A11	S100 calcium binding protein A11	0.015
S100P	S100 calcium binding protein P	0.014	Human
ADAMDEC1	ADAM-like, decysin 1	0.014
TREM1	triggering receptor expressed on myeloid cells 1	0.014
CCR3	chemokine (C-C motif) receptor 3	0.014	Human
NCF4	neutrophil cytosolic factor 4, 40kDa	0.014
TGFB1	transforming growth factor, beta 1	0.014
ICAM1	intercellular adhesion molecule 1	0.014
CLEC5A	C-type lectin domain family 5, member A	0.013
PI3	peptidase inhibitor 3, skin-derived	0.013
CXCR2	chemokine (C-X-C motif) receptor 2	0.013	Human Rat
STAT5A	signal transducer and activator of transcription 5A	0.013
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.013
FPR1	formyl peptide receptor 1	0.013
JAK1	Janus kinase 1	0.013
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.012
INHBA	inhibin, beta A	0.012
C5AR1	complement component 5a receptor 1	0.012	Mouse
DEFB4A	defensin, beta 4A	0.012
IL10RA	interleukin 10 receptor, alpha	0.012
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.011
CD163	CD163 molecule	0.011
BCL2A1	BCL2-related protein A1	0.011
CCR8	chemokine (C-C motif) receptor 8	0.011	Human
RHOC	ras homolog gene family, member C	0.010
CCR6	chemokine (C-C motif) receptor 6	0.010	Human
IL1A	interleukin 1, alpha	0.010