IMP

Process View

Mus musculus

5 genes annotated in mouse

response to arsenic containing substance

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to arsenic containing substance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to arsenic containing substance" (in gray)

Name	Description	Probability	Func Analog Organism
Mapk14	mitogen-activated protein kinase 14	0.998	Yeast Fly
Mapk11	mitogen-activated protein kinase 11	0.858	Yeast Fly
Atf2	activating transcription factor 2	0.772
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.533
Il1a	interleukin 1 alpha	0.442	Zebrafish
Pten	phosphatase and tensin homolog	0.412
Gclm	glutamate-cysteine ligase, modifier subunit	0.335
Gab1	growth factor receptor bound protein 2-associated protein 1	0.305
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.223	Human
Il1b	interleukin 1 beta	0.173	Zebrafish
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.171
Mapk8	mitogen-activated protein kinase 8	0.149	Yeast Fly
Igh	immunoglobulin heavy chain complex	0.114
Mapk1	mitogen-activated protein kinase 1	0.090	Fly
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.083
Slc12a6	solute carrier family 12, member 6	0.066
Mapk9	mitogen-activated protein kinase 9	0.066	Yeast Fly
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.065
S1pr2	sphingosine-1-phosphate receptor 2	0.060
Il6	interleukin 6	0.056
Slpi	secretory leukocyte peptidase inhibitor	0.053
Neurl1a	neuralized homolog 1A (Drosophila)	0.053
Mapk3	mitogen-activated protein kinase 3	0.048	Fly
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.048
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.046
Prkce	protein kinase C, epsilon	0.043
Abcb1a	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	0.043
Bcar1	breast cancer anti-estrogen resistance 1	0.041
Cxcl2	chemokine (C-X-C motif) ligand 2	0.038
Irg1	immunoresponsive gene 1	0.037
Tnf	tumor necrosis factor	0.036	Zebrafish
Cxcl5	chemokine (C-X-C motif) ligand 5	0.034
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.033
Fas	Fas (TNF receptor superfamily member 6)	0.028
Pxn	paxillin	0.027
Ifng	interferon gamma	0.027
Mapkapk2	MAP kinase-activated protein kinase 2	0.026
Apoe	apolipoprotein E	0.026
Eif5	eukaryotic translation initiation factor 5	0.025
Klc1	kinesin light chain 1	0.023
Irak4	interleukin-1 receptor-associated kinase 4	0.022
Cxcl1	chemokine (C-X-C motif) ligand 1	0.021
Trpm7	transient receptor potential cation channel, subfamily M, member 7	0.021
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.021
Stim2	stromal interaction molecule 2	0.021
Sprr1a	small proline-rich protein 1A	0.021
Aplp2	amyloid beta (A4) precursor-like protein 2	0.020
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.020
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.019
Il7	interleukin 7	0.019
Src	Rous sarcoma oncogene	0.019
Fpr1	formyl peptide receptor 1	0.019
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.018	Rat
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.018
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.018
Sqstm1	sequestosome 1	0.017
Saa3	serum amyloid A 3	0.017
Map2k3	mitogen-activated protein kinase kinase 3	0.016
Kif1b	kinesin family member 1B	0.016
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.016
Asprv1	aspartic peptidase, retroviral-like 1	0.015
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.015
Trp53	transformation related protein 53	0.014
Slc12a2	solute carrier family 12, member 2	0.014
Nlrp3	NLR family, pyrin domain containing 3	0.014
Rag2	recombination activating gene 2	0.013
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.013
Rora	RAR-related orphan receptor alpha	0.013
Slc26a7	solute carrier family 26, member 7	0.012
Il1r1	interleukin 1 receptor, type I	0.012
Stat3	signal transducer and activator of transcription 3	0.012
Cd40	CD40 antigen	0.012
Il1r2	interleukin 1 receptor, type II	0.012
Clec4e	C-type lectin domain family 4, member e	0.012
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.012
Gsta4	glutathione S-transferase, alpha 4	0.011
Hao2	hydroxyacid oxidase 2	0.011
Aadac	arylacetamide deacetylase (esterase)	0.011
Ccl2	chemokine (C-C motif) ligand 2	0.011
Gna13	guanine nucleotide binding protein, alpha 13	0.011
Wdr26	WD repeat domain 26	0.011
Slc23a2	solute carrier family 23 (nucleobase transporters), member 2	0.010
Tmem56	transmembrane protein 56	0.010
Mtmr1	myotubularin related protein 1	0.010