Process View
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of histone methylation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.999 | ||
| Suz12 | suppressor of zeste 12 homolog (Drosophila) | 0.993 | ||
| Kdm2b | lysine (K)-specific demethylase 2B | 0.939 | ||
| Jarid2 | jumonji, AT rich interactive domain 2 | 0.911 | ||
| Mtf2 | metal response element binding transcription factor 2 | 0.699 | ||
| Eed | embryonic ectoderm development | 0.619 | ||
| Setx | senataxin | 0.599 | ||
| Dnmt3a | DNA methyltransferase 3A | 0.593 | ||
| Ezh1 | enhancer of zeste homolog 1 (Drosophila) | 0.585 | ||
| Rnf2 | ring finger protein 2 | 0.551 | ||
| Stk38 | serine/threonine kinase 38 | 0.548 | ||
| Smc3 | structural maintenace of chromosomes 3 | 0.458 | ||
| Rbbp4 | retinoblastoma binding protein 4 | 0.399 | ||
| Aebp2 | AE binding protein 2 | 0.392 | ||
| Pax2 | paired box gene 2 | 0.236 | Mouse | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.147 | ||
| Trp63 | transformation related protein 63 | 0.145 | ||
| Shh | sonic hedgehog | 0.132 | ||
| Hells | helicase, lymphoid specific | 0.126 | ||
| Brca2 | breast cancer 2 | 0.124 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.121 | ||
| Sin3a | transcriptional regulator, SIN3A (yeast) | 0.121 | ||
| Kdm1a | lysine (K)-specific demethylase 1A | 0.109 | ||
| BC018507 | cDNA sequence BC018507 | 0.095 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.086 | ||
| Gata3 | GATA binding protein 3 | 0.085 | ||
| Rarg | retinoic acid receptor, gamma | 0.077 | ||
| Trp53 | transformation related protein 53 | 0.075 | ||
| Dnmt1 | DNA methyltransferase (cytosine-5) 1 | 0.070 | Human | |
| Zfp292 | zinc finger protein 292 | 0.063 | ||
| Igl | immunoglobulin lambda chain complex | 0.061 | ||
| Fgf10 | fibroblast growth factor 10 | 0.058 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.057 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.056 | ||
| Atrx | alpha thalassemia/mental retardation syndrome X-linked homolog (human) | 0.046 | ||
| Crebbp | CREB binding protein | 0.044 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.043 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.042 | ||
| Morc3 | microrchidia 3 | 0.041 | ||
| Mbtd1 | mbt domain containing 1 | 0.040 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.039 | ||
| Rb1 | retinoblastoma 1 | 0.036 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.035 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.034 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.034 | ||
| Gata1 | GATA binding protein 1 | 0.034 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.031 | ||
| Nanog | Nanog homeobox | 0.030 | ||
| Trim35 | tripartite motif-containing 35 | 0.030 | ||
| Pax3 | paired box gene 3 | 0.030 | ||
| Ar | androgen receptor | 0.029 | ||
| Med23 | mediator complex subunit 23 | 0.029 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.027 | ||
| Apc | adenomatosis polyposis coli | 0.026 | ||
| Hdac1 | histone deacetylase 1 | 0.025 | ||
| Dlx5 | distal-less homeobox 5 | 0.025 | ||
| Rara | retinoic acid receptor, alpha | 0.024 | ||
| Brd8 | bromodomain containing 8 | 0.023 | ||
| Psen1 | presenilin 1 | 0.023 | ||
| Ylpm1 | YLP motif containing 1 | 0.022 | ||
| Gfi1b | growth factor independent 1B | 0.022 | ||
| Epc1 | enhancer of polycomb homolog 1 (Drosophila) | 0.022 | ||
| Wnt9b | wingless-type MMTV integration site 9B | 0.021 | ||
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.021 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.021 | ||
| Kdm4c | lysine (K)-specific demethylase 4C | 0.021 | ||
| Ilf3 | interleukin enhancer binding factor 3 | 0.020 | ||
| Pax1 | paired box gene 1 | 0.020 | Mouse | |
| Esr1 | estrogen receptor 1 (alpha) | 0.019 | ||
| Alx3 | aristaless-like homeobox 3 | 0.019 | ||
| Rbm22 | RNA binding motif protein 22 | 0.019 | ||
| Dnmt3l | DNA (cytosine-5-)-methyltransferase 3-like | 0.018 | ||
| Cbx8 | chromobox homolog 8 (Drosophila Pc class) | 0.018 | ||
| Pax8 | paired box gene 8 | 0.018 | Mouse | |
| Cd19 | CD19 antigen | 0.018 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.017 | ||
| Paxip1 | PAX interacting (with transcription-activation domain) protein 1 | 0.017 | ||
| Arid1a | AT rich interactive domain 1A (SWI-like) | 0.017 | ||
| Rxra | retinoid X receptor alpha | 0.017 | ||
| Smc1a | structural maintenance of chromosomes 1A | 0.017 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.016 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.016 | ||
| Casp2 | caspase 2 | 0.016 | ||
| Dazap1 | DAZ associated protein 1 | 0.016 | ||
| Clk1 | CDC-like kinase 1 | 0.016 | ||
| Ewsr1 | Ewing sarcoma breakpoint region 1 | 0.015 | ||
| Rnf38 | ring finger protein 38 | 0.015 | ||
| Ly6g6c | lymphocyte antigen 6 complex, locus G6C | 0.015 | ||
| Slc17a8 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 | 0.015 | ||
| 5430421N21Rik | RIKEN cDNA 5430421N21 gene | 0.014 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.014 | ||
| Epor | erythropoietin receptor | 0.014 | ||
| Matr3 | matrin 3 | 0.014 | ||
| Nkx2-1 | NK2 homeobox 1 | 0.014 | ||
| Fgf3 | fibroblast growth factor 3 | 0.014 | ||
| Cbx3 | chromobox homolog 3 (Drosophila HP1 gamma) | 0.013 | ||
| Msx1 | homeobox, msh-like 1 | 0.013 | ||
| Hoxb3 | homeobox B3 | 0.013 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.013 | ||
| Nkx3-2 | NK3 homeobox 2 | 0.013 | ||
| Mesp2 | mesoderm posterior 2 | 0.013 | ||
| Thrap3 | thyroid hormone receptor associated protein 3 | 0.013 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.013 | ||
| Msl1 | male-specific lethal 1 homolog (Drosophila) | 0.013 | ||
| Npc1 | Niemann Pick type C1 | 0.012 | ||
| Nmu | neuromedin U | 0.012 | ||
| Parp1 | poly (ADP-ribose) polymerase family, member 1 | 0.012 | ||
| Epo | erythropoietin | 0.012 | ||
| Hoxa11 | homeobox A11 | 0.012 | ||
| Rag1 | recombination activating gene 1 | 0.012 | ||
| Wnt3a | wingless-related MMTV integration site 3A | 0.012 | ||
| Kdm5a | lysine (K)-specific demethylase 5A | 0.012 | ||
| Fbxo38 | F-box protein 38 | 0.012 | ||
| Trim33 | tripartite motif-containing 33 | 0.011 | ||
| Csnk2a1 | casein kinase 2, alpha 1 polypeptide | 0.011 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.011 | ||
| Uhrf1 | ubiquitin-like, containing PHD and RING finger domains, 1 | 0.011 | ||
| Ahr | aryl-hydrocarbon receptor | 0.011 | ||
| Thrb | thyroid hormone receptor beta | 0.011 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.011 | ||
| Ell | elongation factor RNA polymerase II | 0.011 | ||
| Atr | ataxia telangiectasia and Rad3 related | 0.011 | ||
| Kcne1 | potassium voltage-gated channel, Isk-related subfamily, member 1 | 0.011 | ||
| Dtl | denticleless homolog (Drosophila) | 0.011 | ||
| Dpf2 | D4, zinc and double PHD fingers family 2 | 0.011 | ||
| Kdm3a | lysine (K)-specific demethylase 3A | 0.011 | ||
| Cdh23 | cadherin 23 (otocadherin) | 0.010 | ||
| Col2a1 | collagen, type II, alpha 1 | 0.010 | ||
| Foxo1 | forkhead box O1 | 0.010 | ||
| Runx2 | runt related transcription factor 2 | 0.010 | ||
| Csnk2a2 | casein kinase 2, alpha prime polypeptide | 0.010 | ||
| Blm | Bloom syndrome, RecQ helicase-like | 0.010 | ||
| Ncoa6 | nuclear receptor coactivator 6 | 0.010 | ||
| Pten | phosphatase and tensin homolog | 0.010 |