IMP

Process View

Mus musculus

1 genes annotated in mouse

Multi-species View

positive regulation of interleukin 5 secretion

GO:2000664

Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of interleukin 5 secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of interleukin 5 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Bcl2	B-cell leukemia/lymphoma 2	0.602
Vhl	von Hippel-Lindau tumor suppressor	0.447
Akt1	thymoma viral proto-oncogene 1	0.395	Mouse
Akt2	thymoma viral proto-oncogene 2	0.321	Mouse
Myo6	myosin VI	0.242
Ldb3	LIM domain binding 3	0.239
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.216
Vegfa	vascular endothelial growth factor A	0.203
Pax2	paired box gene 2	0.180
Prkce	protein kinase C, epsilon	0.152
Kit	kit oncogene	0.138
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.134
Vangl2	vang-like 2 (van gogh, Drosophila)	0.126
Mlf2	myeloid leukemia factor 2	0.120
Cd28	CD28 antigen	0.120
Fas	Fas (TNF receptor superfamily member 6)	0.114
Pparg	peroxisome proliferator activated receptor gamma	0.113
Csnk1g2	casein kinase 1, gamma 2	0.108
Igh	immunoglobulin heavy chain complex	0.107
Igf1r	insulin-like growth factor I receptor	0.104
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.101
Mapkap1	mitogen-activated protein kinase associated protein 1	0.101
Ilk	integrin linked kinase	0.094
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.092
Actn2	actinin alpha 2	0.086
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.078
Blnk	B-cell linker	0.078
Plcb1	phospholipase C, beta 1	0.075
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.068
Rasgrp1	RAS guanyl releasing protein 1	0.066
Mapkapk2	MAP kinase-activated protein kinase 2	0.065
Slc39a7	solute carrier family 39 (zinc transporter), member 7	0.064
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.061
Apc	adenomatosis polyposis coli	0.059
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.058
Fgfr2	fibroblast growth factor receptor 2	0.056
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.053
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.052
Gsk3b	glycogen synthase kinase 3 beta	0.049
Dtx1	deltex 1 homolog (Drosophila)	0.048
Add1	adducin 1 (alpha)	0.048
Icos	inducible T-cell co-stimulator	0.046
Rarg	retinoic acid receptor, gamma	0.046
Chd7	chromodomain helicase DNA binding protein 7	0.045
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.042
Klc1	kinesin light chain 1	0.042
Gjb2	gap junction protein, beta 2	0.041
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.038
Efnb2	ephrin B2	0.036
Prkcb	protein kinase C, beta	0.035
Ctdnep1	CTD nuclear envelope phosphatase 1	0.034
Notch1	Notch gene homolog 1 (Drosophila)	0.034
S1pr2	sphingosine-1-phosphate receptor 2	0.034
Arf3	ADP-ribosylation factor 3	0.033
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.033
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.033
Arhgap1	Rho GTPase activating protein 1	0.033
Actn4	actinin alpha 4	0.032
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.031
Atp11c	ATPase, class VI, type 11C	0.030
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.029
Capn1	calpain 1	0.029
Zeb1	zinc finger E-box binding homeobox 1	0.029
Aamp	angio-associated migratory protein	0.029
Cd19	CD19 antigen	0.028
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.028
Hoxa1	homeobox A1	0.028
Dctn1	dynactin 1	0.027
Dgcr2	DiGeorge syndrome critical region gene 2	0.027
Eya1	eyes absent 1 homolog (Drosophila)	0.027
Ar	androgen receptor	0.026
Git1	G protein-coupled receptor kinase-interactor 1	0.026
Stat6	signal transducer and activator of transcription 6	0.026
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.025
Pten	phosphatase and tensin homolog	0.025
Gna12	guanine nucleotide binding protein, alpha 12	0.025
Ikzf1	IKAROS family zinc finger 1	0.024
Kctd20	potassium channel tetramerisation domain containing 20	0.024
Hdac7	histone deacetylase 7	0.024
Homer1	homer homolog 1 (Drosophila)	0.023
Cd151	CD151 antigen	0.023
Nudt3	nudix (nucleotide diphosphate linked moiety X)-type motif 3	0.023
Jag1	jagged 1	0.023
Coro1c	coronin, actin binding protein 1C	0.023
Pfkl	phosphofructokinase, liver, B-type	0.022
Cdk14	cyclin-dependent kinase 14	0.022
Prkca	protein kinase C, alpha	0.022
Itga3	integrin alpha 3	0.022
Lats1	large tumor suppressor	0.022
Ush1g	Usher syndrome 1G homolog (human)	0.022
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.021
Lat	linker for activation of T cells	0.021
Ldb1	LIM domain binding 1	0.021
Ncln	nicalin homolog (zebrafish)	0.021
Lef1	lymphoid enhancer binding factor 1	0.021
Foxo1	forkhead box O1	0.020
Ncoa3	nuclear receptor coactivator 3	0.020
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.020
Arpc4	actin related protein 2/3 complex, subunit 4	0.020
Phlpp1	PH domain and leucine rich repeat protein phosphatase 1	0.020
Sox4	SRY-box containing gene 4	0.019
Cd79b	CD79B antigen	0.019
Foxg1	forkhead box G1	0.019
Vasp	vasodilator-stimulated phosphoprotein	0.019
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.019
Rasal1	RAS protein activator like 1 (GAP1 like)	0.018
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.018
Pex5	peroxisomal biogenesis factor 5	0.018
Usp22	ubiquitin specific peptidase 22	0.017
Rictor	RPTOR independent companion of MTOR, complex 2	0.017
Bcl6	B-cell leukemia/lymphoma 6	0.017
Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2	0.016
Rora	RAR-related orphan receptor alpha	0.016
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.016
Bag6	BCL2-associated athanogene 6	0.016
Wrn	Werner syndrome homolog (human)	0.016
Atp8a1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	0.016
Rap1gap	Rap1 GTPase-activating protein	0.016
Kif3b	kinesin family member 3B	0.016
L1cam	L1 cell adhesion molecule	0.016
Mapk3	mitogen-activated protein kinase 3	0.016
Rab25	RAB25, member RAS oncogene family	0.016
Fastk	Fas-activated serine/threonine kinase	0.016
Mgrn1	mahogunin, ring finger 1	0.016
Sec31a	Sec31 homolog A (S. cerevisiae)	0.015
Plxna1	plexin A1	0.015
Abca2	ATP-binding cassette, sub-family A (ABC1), member 2	0.015
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.015
Alkbh1	alkB, alkylation repair homolog 1 (E. coli)	0.015
Slc26a4	solute carrier family 26, member 4	0.015
Dusp7	dual specificity phosphatase 7	0.014
Sec14l1	SEC14-like 1 (S. cerevisiae)	0.014
Adrbk1	adrenergic receptor kinase, beta 1	0.014
Stub1	STIP1 homology and U-Box containing protein 1	0.014
Pacs2	phosphofurin acidic cluster sorting protein 2	0.014
Dll1	delta-like 1 (Drosophila)	0.014
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.014
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.014
Limk2	LIM motif-containing protein kinase 2	0.014
Rap1gds1	RAP1, GTP-GDP dissociation stimulator 1	0.014
Ahi1	Abelson helper integration site 1	0.014
Tnip1	TNFAIP3 interacting protein 1	0.013
Plcg1	phospholipase C, gamma 1	0.013
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.013
Rxra	retinoid X receptor alpha	0.013
Rac1	RAS-related C3 botulinum substrate 1	0.013
Mgat3	mannoside acetylglucosaminyltransferase 3	0.013
Ctnnd1	catenin (cadherin associated protein), delta 1	0.013
Gipc1	GIPC PDZ domain containing family, member 1	0.013
Lyst	lysosomal trafficking regulator	0.013
Man1a2	mannosidase, alpha, class 1A, member 2	0.013
Src	Rous sarcoma oncogene	0.013
Csnk1e	casein kinase 1, epsilon	0.013
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.012
Trim46	tripartite motif-containing 46	0.012
Il27ra	interleukin 27 receptor, alpha	0.012
Sox2	SRY-box containing gene 2	0.012
Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.012
Csnk1d	casein kinase 1, delta	0.012
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.012
Plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	0.012
Tgfbr1	transforming growth factor, beta receptor I	0.012
Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.012
Hpcal4	hippocalcin-like 4	0.012
Tcf7	transcription factor 7, T-cell specific	0.012
Npy1r	neuropeptide Y receptor Y1	0.012
Klc2	kinesin light chain 2	0.012
Mapk8	mitogen-activated protein kinase 8	0.011
Psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.011
Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent	0.011
Btbd10	BTB (POZ) domain containing 10	0.011
Kif3a	kinesin family member 3A	0.011
Myo9a	myosin IXa	0.011
Trim35	tripartite motif-containing 35	0.011
Map3k5	mitogen-activated protein kinase kinase kinase 5	0.011
Rnf208	ring finger protein 208	0.011
Vsnl1	visinin-like 1	0.011
Traf6	TNF receptor-associated factor 6	0.011
Nefh	neurofilament, heavy polypeptide	0.011
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.011
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.011
Nf1	neurofibromatosis 1	0.011
Tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.011
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.011
Txndc5	thioredoxin domain containing 5	0.011
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.011
Traf3ip2	TRAF3 interacting protein 2	0.011
Espn	espin	0.011
Tubb4	tubulin, beta 4	0.011
Csrp1	cysteine and glycine-rich protein 1	0.011
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.011
Sorl1	sortilin-related receptor, LDLR class A repeats-containing	0.010
Mark2	MAP/microtubule affinity-regulating kinase 2	0.010
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.010
Kifc2	kinesin family member C2	0.010
Grm8	glutamate receptor, metabotropic 8	0.010