IMP
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b 1 b cell differentiation
The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "b 1 b cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.485 | ||
| Homer1 | homer homolog 1 (Drosophila) | 0.168 | ||
| Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 0.158 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.109 | ||
| Shank2 | SH3/ankyrin domain gene 2 | 0.094 | ||
| Sh3kbp1 | SH3-domain kinase binding protein 1 | 0.092 | ||
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.089 | ||
| Blnk | B-cell linker | 0.077 | ||
| Cd22 | CD22 antigen | 0.076 | ||
| Prkch | protein kinase C, eta | 0.061 | ||
| Tcrd | T-cell receptor delta chain | 0.058 | ||
| Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.058 | ||
| Nf1 | neurofibromatosis 1 | 0.053 | ||
| Epor | erythropoietin receptor | 0.039 | ||
| Trim27 | tripartite motif-containing 27 | 0.037 | ||
| Dlgap1 | discs, large (Drosophila) homolog-associated protein 1 | 0.036 | ||
| Prkcc | protein kinase C, gamma | 0.035 | ||
| Hmha1 | histocompatibility (minor) HA-1 | 0.035 | ||
| Epb4.1l2 | erythrocyte protein band 4.1-like 2 | 0.035 | ||
| Lat | linker for activation of T cells | 0.034 | ||
| Dynlt1b | dynein light chain Tctex-type 1D | 0.034 | ||
| Plcb3 | phospholipase C, beta 3 | 0.033 | Mouse | |
| Prkcd | protein kinase C, delta | 0.032 | ||
| Grm1 | glutamate receptor, metabotropic 1 | 0.032 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.032 | ||
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.031 | ||
| Ephb3 | Eph receptor B3 | 0.031 | ||
| Dlg2 | discs, large homolog 2 (Drosophila) | 0.031 | ||
| Pstpip1 | proline-serine-threonine phosphatase-interacting protein 1 | 0.031 | ||
| Cit | citron | 0.028 | ||
| S100a4 | S100 calcium binding protein A4 | 0.026 | ||
| Prkcb | protein kinase C, beta | 0.026 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.026 | ||
| Cd79a | CD79A antigen (immunoglobulin-associated alpha) | 0.024 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.021 | ||
| Dok1 | docking protein 1 | 0.021 | ||
| Ptk2b | PTK2 protein tyrosine kinase 2 beta | 0.021 | ||
| Dsg1a | desmoglein 1 alpha | 0.020 | ||
| Itpr1 | inositol 1,4,5-trisphosphate receptor 1 | 0.020 | ||
| Sync | syncoilin | 0.020 | ||
| Cd46 | CD46 antigen, complement regulatory protein | 0.019 | ||
| Smtn | smoothelin | 0.019 | ||
| Gys1 | glycogen synthase 1, muscle | 0.019 | ||
| Arc | activity regulated cytoskeletal-associated protein | 0.019 | ||
| Grik2 | glutamate receptor, ionotropic, kainate 2 (beta 2) | 0.019 | ||
| Dnm1 | dynamin 1 | 0.019 | ||
| Atxn1 | ataxin 1 | 0.019 | ||
| Rasgrf2 | RAS protein-specific guanine nucleotide-releasing factor 2 | 0.018 | ||
| Des | desmin | 0.018 | ||
| Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 | 0.017 | ||
| Dtna | dystrobrevin alpha | 0.017 | ||
| Sema3b | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.016 | ||
| Parvg | parvin, gamma | 0.015 | ||
| Tnfrsf13c | tumor necrosis factor receptor superfamily, member 13c | 0.015 | ||
| Adcy1 | adenylate cyclase 1 | 0.015 | ||
| Cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.015 | ||
| Gria1 | glutamate receptor, ionotropic, AMPA1 (alpha 1) | 0.015 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.015 | ||
| Cttn | cortactin | 0.015 | ||
| Tcirg1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 | 0.015 | ||
| Kdr | kinase insert domain protein receptor | 0.015 | ||
| Plcb1 | phospholipase C, beta 1 | 0.014 | Mouse | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.014 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.014 | ||
| L1cam | L1 cell adhesion molecule | 0.014 | ||
| Hs3st3a1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.014 | ||
| Utrn | utrophin | 0.014 | ||
| Card11 | caspase recruitment domain family, member 11 | 0.014 | ||
| Dpysl2 | dihydropyrimidinase-like 2 | 0.014 | ||
| Actn2 | actinin alpha 2 | 0.014 | ||
| Ulk3 | unc-51-like kinase 3 (C. elegans) | 0.014 | ||
| Pld2 | phospholipase D2 | 0.014 | ||
| Prx | periaxin | 0.014 | ||
| Capg | capping protein (actin filament), gelsolin-like | 0.014 | ||
| Rps6ka1 | ribosomal protein S6 kinase polypeptide 1 | 0.013 | ||
| Ids | iduronate 2-sulfatase | 0.013 | ||
| Lrmp | lymphoid-restricted membrane protein | 0.013 | ||
| Prkce | protein kinase C, epsilon | 0.013 | ||
| Per3 | period homolog 3 (Drosophila) | 0.013 | ||
| Stk11 | serine/threonine kinase 11 | 0.013 | ||
| Dvl2 | dishevelled 2, dsh homolog (Drosophila) | 0.013 | ||
| Tenc1 | tensin like C1 domain-containing phosphatase | 0.013 | ||
| Myh10 | myosin, heavy polypeptide 10, non-muscle | 0.013 | ||
| Rgs19 | regulator of G-protein signaling 19 | 0.013 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.013 | ||
| Plekhh3 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 | 0.013 | ||
| Srgap1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.012 | ||
| Mid2 | midline 2 | 0.012 | ||
| Cacnb3 | calcium channel, voltage-dependent, beta 3 subunit | 0.012 | ||
| Lama5 | laminin, alpha 5 | 0.012 | ||
| Cd72 | CD72 antigen | 0.012 | ||
| Gsn | gelsolin | 0.012 | ||
| Dnase1l2 | deoxyribonuclease 1-like 2 | 0.012 | ||
| H2-T18 | histocompatibility 2, T region locus 18 | 0.012 | ||
| Cdk14 | cyclin-dependent kinase 14 | 0.012 | ||
| Wdsub1 | WD repeat, SAM and U-box domain containing 1 | 0.011 | ||
| Npas2 | neuronal PAS domain protein 2 | 0.011 | ||
| Hivep3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.011 | ||
| Zbtb7b | zinc finger and BTB domain containing 7B | 0.011 | ||
| Dock8 | dedicator of cytokinesis 8 | 0.011 | ||
| Itpr2 | inositol 1,4,5-triphosphate receptor 2 | 0.011 | ||
| Map4k1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.011 | ||
| Itch | itchy, E3 ubiquitin protein ligase | 0.011 | ||
| Rps6ka3 | ribosomal protein S6 kinase polypeptide 3 | 0.011 | ||
| Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.011 | ||
| Camk2b | calcium/calmodulin-dependent protein kinase II, beta | 0.011 | ||
| Ptger1 | prostaglandin E receptor 1 (subtype EP1) | 0.011 | ||
| Irf4 | interferon regulatory factor 4 | 0.011 | ||
| Dok3 | docking protein 3 | 0.011 | ||
| Pfkfb2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | 0.011 | ||
| Marveld1 | MARVEL (membrane-associating) domain containing 1 | 0.010 | ||
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.010 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.010 | ||
| Plxna1 | plexin A1 | 0.010 | ||
| C77370 | expressed sequence C77370 | 0.010 | ||
| Plekha2 | pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2 | 0.010 | ||
| Kif1b | kinesin family member 1B | 0.010 | ||
| Plp1 | proteolipid protein (myelin) 1 | 0.010 | ||
| Arhgef25 | Rho guanine nucleotide exchange factor (GEF) 25 | 0.010 |