IMP

Process View

Mus musculus

11 genes annotated in mouse

facial nerve development

The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "facial nerve development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "facial nerve development" (in gray)

Name	Description	Probability	Func Analog Organism
Arhgef11	Rho guanine nucleotide exchange factor (GEF) 11	0.997
Hoxa2	homeobox A2	0.958	Mouse
Eya1	eyes absent 1 homolog (Drosophila)	0.950
Pbx1	pre B-cell leukemia transcription factor 1	0.881
Otx2	orthodenticle homolog 2 (Drosophila)	0.862
Egr2	early growth response 2	0.812
Ednra	endothelin receptor type A	0.808
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.758	Mouse
Plxna1	plexin A1	0.693	Mouse
Hoxb2	homeobox B2	0.546
Nrp1	neuropilin 1	0.522
Hoxd3	homeobox D3	0.470
Nab2	Ngfi-A binding protein 2	0.416
Dlx5	distal-less homeobox 5	0.409
Prrx1	paired related homeobox 1	0.406
Rarg	retinoic acid receptor, gamma	0.363
Tcfap2a	transcription factor AP-2, alpha	0.342
Hoxa3	homeobox A3	0.308
Hoxb1	homeobox B1	0.305
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.304
Hoxa1	homeobox A1	0.302
Notch3	Notch gene homolog 3 (Drosophila)	0.283
Plxnd1	plexin D1	0.246	Mouse
Hoxb3	homeobox B3	0.177
Lama5	laminin, alpha 5	0.157
Bcl2	B-cell leukemia/lymphoma 2	0.154
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.145
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.139
Msx1	homeobox, msh-like 1	0.138
Tbx1	T-box 1	0.120
Fos	FBJ osteosarcoma oncogene	0.098
Hoxb4	homeobox B4	0.096
Lhx9	LIM homeobox protein 9	0.094
Dlg4	discs, large homolog 4 (Drosophila)	0.092
Flt1	FMS-like tyrosine kinase 1	0.088
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.082
Gli3	GLI-Kruppel family member GLI3	0.080
Otx1	orthodenticle homolog 1 (Drosophila)	0.079
Emp2	epithelial membrane protein 2	0.078
Vegfa	vascular endothelial growth factor A	0.072
Ebf3	early B-cell factor 3	0.071
Apc2	adenomatosis polyposis coli 2	0.071
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.069
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.068
Rarb	retinoic acid receptor, beta	0.067
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.066
Gdnf	glial cell line derived neurotrophic factor	0.062
Pax3	paired box gene 3	0.061
Emx2	empty spiracles homolog 2 (Drosophila)	0.058
Gli2	GLI-Kruppel family member GLI2	0.057
Aplnr	apelin receptor	0.056
Pax2	paired box gene 2	0.054
Zic2	zinc finger protein of the cerebellum 2	0.054
Fgfr1	fibroblast growth factor receptor 1	0.053
Fzd1	frizzled homolog 1 (Drosophila)	0.053
Nynrin	NYN domain and retroviral integrase containing	0.052
Nrp2	neuropilin 2	0.049
Msx2	homeobox, msh-like 2	0.046
Tcf21	transcription factor 21	0.045
Epha4	Eph receptor A4	0.045
Smad3	MAD homolog 3 (Drosophila)	0.044
Grb10	growth factor receptor bound protein 10	0.041
Isl1	ISL1 transcription factor, LIM/homeodomain	0.041
Tbx2	T-box 2	0.040
Lhx1	LIM homeobox protein 1	0.037
Ltbp1	latent transforming growth factor beta binding protein 1	0.037
Etl4	enhancer trap locus 4	0.037
Nab1	Ngfi-A binding protein 1	0.034
Neo1	neogenin	0.033
Ptrf	polymerase I and transcript release factor	0.033
Ptgs2	prostaglandin-endoperoxide synthase 2	0.033
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.032
Dach1	dachshund 1 (Drosophila)	0.032
Gbx2	gastrulation brain homeobox 2	0.031
Rara	retinoic acid receptor, alpha	0.031
Phox2b	paired-like homeobox 2b	0.030
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.030
Smad5	MAD homolog 5 (Drosophila)	0.030
Mmp15	matrix metallopeptidase 15	0.029
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.029
Lmx1a	LIM homeobox transcription factor 1 alpha	0.029
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.029
Fzd2	frizzled homolog 2 (Drosophila)	0.028
Tead3	TEA domain family member 3	0.028
Bnc1	basonuclin 1	0.027
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.027
Junb	Jun-B oncogene	0.026
Mid2	midline 2	0.026
Ptch1	patched homolog 1	0.026
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.026
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.025
Fign	fidgetin	0.025
Foxi3	forkhead box I3	0.025
Hoxa5	homeobox A5	0.025
Tspan9	tetraspanin 9	0.024
Rgnef	Rho-guanine nucleotide exchange factor	0.024
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.023
Sdc3	syndecan 3	0.023
Gpc3	glypican 3	0.023
Ednrb	endothelin receptor type B	0.022
Hoxa11	homeobox A11	0.022
Osr1	odd-skipped related 1 (Drosophila)	0.021
Bcl6b	B-cell CLL/lymphoma 6, member B	0.021
Sh3rf1	SH3 domain containing ring finger 1	0.020
Plxna4	plexin A4	0.020
Sox7	SRY-box containing gene 7	0.020
Ece1	endothelin converting enzyme 1	0.020
Htt	huntingtin	0.019
Nog	noggin	0.019
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.019
Npnt	nephronectin	0.018
Tlx3	T-cell leukemia, homeobox 3	0.018
Cachd1	cache domain containing 1	0.018
Itm2c	integral membrane protein 2C	0.018
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.018
Prkci	protein kinase C, iota	0.018
Hoxb5	homeobox B5	0.018
Ddr2	discoidin domain receptor family, member 2	0.018
Unc5c	unc-5 homolog C (C. elegans)	0.017
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.017
Ntf3	neurotrophin 3	0.017
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.016
Btbd3	BTB (POZ) domain containing 3	0.016
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.016
Fzd8	frizzled homolog 8 (Drosophila)	0.016
Foxc2	forkhead box C2	0.016
Cacng7	calcium channel, voltage-dependent, gamma subunit 7	0.016
Foxp2	forkhead box P2	0.016
Dock4	dedicator of cytokinesis 4	0.016
Fgf10	fibroblast growth factor 10	0.016
Myf5	myogenic factor 5	0.015
Cdk14	cyclin-dependent kinase 14	0.015
Fosb	FBJ osteosarcoma oncogene B	0.015
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.015
Egr1	early growth response 1	0.015	Mouse
Id1	inhibitor of DNA binding 1	0.014
Polm	polymerase (DNA directed), mu	0.014
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.014
Lrp1	low density lipoprotein receptor-related protein 1	0.014
En1	engrailed 1	0.014
Hand1	heart and neural crest derivatives expressed transcript 1	0.014
Kdr	kinase insert domain protein receptor	0.013
Zfhx4	zinc finger homeodomain 4	0.013
Jun	Jun oncogene	0.013
Ctf1	cardiotrophin 1	0.013
Eya4	eyes absent 4 homolog (Drosophila)	0.013
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.013
Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog	0.013
Hoxb6	homeobox B6	0.012
Neurog1	neurogenin 1	0.012
Btg2	B-cell translocation gene 2, anti-proliferative	0.012
Cdh13	cadherin 13	0.012
Fzd7	frizzled homolog 7 (Drosophila)	0.012
Fgf3	fibroblast growth factor 3	0.012
Bdnf	brain derived neurotrophic factor	0.012
Wnt1	wingless-related MMTV integration site 1	0.012
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.012
Pax7	paired box gene 7	0.012
Col4a5	collagen, type IV, alpha 5	0.012
Dpysl2	dihydropyrimidinase-like 2	0.012
Ptpre	protein tyrosine phosphatase, receptor type, E	0.012
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.012
Hmx1	H6 homeobox 1	0.012
Efs	embryonal Fyn-associated substrate	0.012
Bmp7	bone morphogenetic protein 7	0.012
Matn4	matrilin 4	0.012
Foxd1	forkhead box D1	0.012
Cyr61	cysteine rich protein 61	0.011
Gsc	goosecoid homeobox	0.011
Epha3	Eph receptor A3	0.011
Ier2	immediate early response 2	0.011
Socs3	suppressor of cytokine signaling 3	0.011
Nf1	neurofibromatosis 1	0.011
Fgf8	fibroblast growth factor 8	0.011
Tbx18	T-box18	0.011
Meis2	Meis homeobox 2	0.011
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.011	Mouse
Sox3	SRY-box containing gene 3	0.011
Hes1	hairy and enhancer of split 1 (Drosophila)	0.011
Fbln1	fibulin 1	0.011
Nanog	Nanog homeobox	0.011
Msi1	Musashi homolog 1(Drosophila)	0.011
Hoxa4	homeobox A4	0.010
Acvr1	activin A receptor, type 1	0.010
Fzd9	frizzled homolog 9 (Drosophila)	0.010
Disp1	dispatched homolog 1 (Drosophila)	0.010
Hoxd1	homeobox D1	0.010	Mouse
Irx3	Iroquois related homeobox 3 (Drosophila)	0.010