IMP

Process View

Mus musculus

0 genes annotated in mouse

lymphatic system disease

DOID:75

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lymphatic system disease" (in gray)

Name	Description	Probability	Func Analog Organism
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.976
Kdr	kinase insert domain protein receptor	0.891
Rab27a	RAB27A, member RAS oncogene family	0.826
Lrp1	low density lipoprotein receptor-related protein 1	0.507
Lyz2	lysozyme 2	0.477
Ldlr	low density lipoprotein receptor	0.323
Vegfc	vascular endothelial growth factor C	0.304	Human
Lepr	leptin receptor	0.220
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.213
Npc1	Niemann Pick type C1	0.176	Human
Nlrp3	NLR family, pyrin domain containing 3	0.155
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.149
Flt4	FMS-like tyrosine kinase 4	0.106	Human
Ctsd	cathepsin D	0.104
App	amyloid beta (A4) precursor protein	0.100
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.086
Gpr116	G protein-coupled receptor 116	0.086
Prnp	prion protein	0.086
Inpp5d	inositol polyphosphate-5-phosphatase D	0.076
Psap	prosaposin	0.068
Foxp3	forkhead box P3	0.062
Lyst	lysosomal trafficking regulator	0.061
Il10	interleukin 10	0.060
Hexa	hexosaminidase A	0.060
Trp53	transformation related protein 53	0.060
Nos3	nitric oxide synthase 3, endothelial cell	0.059
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.053
Ikbkg	inhibitor of kappaB kinase gamma	0.050
Heg1	HEG homolog 1 (zebrafish)	0.047
Cd28	CD28 antigen	0.047
Esr1	estrogen receptor 1 (alpha)	0.046
Lamp1	lysosomal-associated membrane protein 1	0.046
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.044
Stat1	signal transducer and activator of transcription 1	0.043
Pparg	peroxisome proliferator activated receptor gamma	0.041
Gba	glucosidase, beta, acid	0.041
Stx11	syntaxin 11	0.040	Human
Pten	phosphatase and tensin homolog	0.039
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.037
Tmem204	transmembrane protein 204	0.037
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.035
Lgmn	legumain	0.035
Il6	interleukin 6	0.034
Scarb1	scavenger receptor class B, member 1	0.033
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.033
Gaa	glucosidase, alpha, acid	0.032
Agtr1a	angiotensin II receptor, type 1a	0.032
Gpr182	G protein-coupled receptor 182	0.031
Ctsb	cathepsin B	0.031
Igf1	insulin-like growth factor 1	0.030
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.030
Ifngr1	interferon gamma receptor 1	0.029
Foxo3	forkhead box O3	0.028
Pltp	phospholipid transfer protein	0.027
Tpp1	tripeptidyl peptidase I	0.026
Tnfaip8l2	tumor necrosis factor, alpha-induced protein 8-like 2	0.026
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.026
Cfh	complement component factor h	0.025
Mmp9	matrix metallopeptidase 9	0.025
Cav1	caveolin 1, caveolae protein	0.025
Ghr	growth hormone receptor	0.024
Rag1	recombination activating gene 1	0.024
C3	complement component 3	0.024
Fas	Fas (TNF receptor superfamily member 6)	0.023
Grn	granulin	0.023
Rxra	retinoid X receptor alpha	0.022
Ar	androgen receptor	0.021
Lpin1	lipin 1	0.021
Irs2	insulin receptor substrate 2	0.020
Mt1	metallothionein 1	0.020
Mecp2	methyl CpG binding protein 2	0.020
Vegfa	vascular endothelial growth factor A	0.019
Cdh5	cadherin 5	0.019
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.019
Klf15	Kruppel-like factor 15	0.018
Myo6	myosin VI	0.017
Pecam1	platelet/endothelial cell adhesion molecule 1	0.017
Angptl4	angiopoietin-like 4	0.016
Gfi1	growth factor independent 1	0.016
Stat3	signal transducer and activator of transcription 3	0.016
Atp6v0e	ATPase, H+ transporting, lysosomal V0 subunit E	0.015
Gns	glucosamine (N-acetyl)-6-sulfatase	0.015
Mt2	metallothionein 2	0.015
Scd1	stearoyl-Coenzyme A desaturase 1	0.015
Aplp2	amyloid beta (A4) precursor-like protein 2	0.015
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.015
Apoe	apolipoprotein E	0.015	Human
Lgals3	lectin, galactose binding, soluble 3	0.015
Dpp7	dipeptidylpeptidase 7	0.015
Tex264	testis expressed gene 264	0.015
Mertk	c-mer proto-oncogene tyrosine kinase	0.014
Itm2c	integral membrane protein 2C	0.014
Npc2	Niemann Pick type C2	0.014	Human
Cstb	cystatin B	0.014
Stat6	signal transducer and activator of transcription 6	0.014
Egr1	early growth response 1	0.013
Tnf	tumor necrosis factor	0.013
Esam	endothelial cell-specific adhesion molecule	0.013
Dap	death-associated protein	0.013
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.012
Cd19	CD19 antigen	0.012
Ctsz	cathepsin Z	0.012
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.012
Kit	kit oncogene	0.012
Ctsa	cathepsin A	0.012
Cst3	cystatin C	0.012
Atp6v0d1	ATPase, H+ transporting, lysosomal V0 subunit D1	0.011
Eng	endoglin	0.011
Sox18	SRY-box containing gene 18	0.011
Idua	iduronidase, alpha-L-	0.010
S1pr1	sphingosine-1-phosphate receptor 1	0.010