Process View
The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "apoptotic dna fragmentation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Casp1 | caspase 1 | 0.884 | Mouse | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.865 | Mouse | |
| Aim2 | absent in melanoma 2 | 0.734 | ||
| Gbp5 | guanylate binding protein 5 | 0.666 | ||
| Pycard | PYD and CARD domain containing | 0.480 | ||
| Plin1 | perilipin 1 | 0.443 | ||
| Il18 | interleukin 18 | 0.283 | ||
| Tlr4 | toll-like receptor 4 | 0.216 | ||
| Dffb | DNA fragmentation factor, beta subunit | 0.208 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.078 | ||
| Il1b | interleukin 1 beta | 0.057 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.056 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.054 | ||
| Rbl1 | retinoblastoma-like 1 (p107) | 0.053 | ||
| Atr | ataxia telangiectasia and Rad3 related | 0.052 | ||
| Cidec | cell death-inducing DFFA-like effector c | 0.050 | Mouse | |
| Bak1 | BCL2-antagonist/killer 1 | 0.042 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.040 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.037 | ||
| Lbr | lamin B receptor | 0.034 | ||
| Stat1 | signal transducer and activator of transcription 1 | 0.033 | ||
| Cfd | complement factor D (adipsin) | 0.033 | ||
| Hhat | hedgehog acyltransferase | 0.027 | ||
| Kit | kit oncogene | 0.027 | ||
| Cidea | cell death-inducing DNA fragmentation factor, alpha subunit-like effector A | 0.025 | ||
| Lyz2 | lysozyme 2 | 0.025 | ||
| Rb1 | retinoblastoma 1 | 0.025 | ||
| Prkab1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit | 0.024 | ||
| Cox5a | cytochrome c oxidase, subunit Va | 0.024 | ||
| Mcm7 | minichromosome maintenance deficient 7 (S. cerevisiae) | 0.023 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.022 | ||
| Uqcrc2 | ubiquinol cytochrome c reductase core protein 2 | 0.022 | ||
| Bid | BH3 interacting domain death agonist | 0.022 | ||
| Adam10 | a disintegrin and metallopeptidase domain 10 | 0.020 | ||
| Trp53 | transformation related protein 53 | 0.020 | ||
| Ndufab1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1 | 0.018 | ||
| Mobkl1b | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.018 | ||
| Birc3 | baculoviral IAP repeat-containing 3 | 0.018 | ||
| Lyst | lysosomal trafficking regulator | 0.018 | ||
| Foxp3 | forkhead box P3 | 0.017 | ||
| Retn | resistin | 0.017 | ||
| Plin4 | perilipin 4 | 0.017 | ||
| Cdk4 | cyclin-dependent kinase 4 | 0.016 | ||
| Gbp7 | guanylate binding protein 7 | 0.016 | ||
| Ndufaf4 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4 | 0.015 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.015 | ||
| Gbp3 | guanylate binding protein 3 | 0.014 | ||
| Mcm3 | minichromosome maintenance deficient 3 (S. cerevisiae) | 0.014 | ||
| Gcsh | glycine cleavage system protein H (aminomethyl carrier) | 0.014 | ||
| Igh | immunoglobulin heavy chain complex | 0.014 | ||
| Dck | deoxycytidine kinase | 0.014 | ||
| Ikbkb | inhibitor of kappaB kinase beta | 0.013 | ||
| Safb | scaffold attachment factor B | 0.013 | ||
| Mrpl18 | mitochondrial ribosomal protein L18 | 0.013 | ||
| Fadd | Fas (TNFRSF6)-associated via death domain | 0.013 | ||
| Casp7 | caspase 7 | 0.012 | Mouse | |
| Ndufa12 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 | 0.012 | ||
| Nans | N-acetylneuraminic acid synthase (sialic acid synthase) | 0.012 | ||
| Tfam | transcription factor A, mitochondrial | 0.012 | ||
| Adig | adipogenin | 0.011 | ||
| Pola1 | polymerase (DNA directed), alpha 1 | 0.011 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.011 | ||
| Ints7 | integrator complex subunit 7 | 0.010 | ||
| Mlh1 | mutL homolog 1 (E. coli) | 0.010 | ||
| Ripk3 | receptor-interacting serine-threonine kinase 3 | 0.010 | ||
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.010 | ||
| Mcm4 | minichromosome maintenance deficient 4 homolog (S. cerevisiae) | 0.010 | ||
| Drosha | drosha, ribonuclease type III | 0.010 | ||
| Casp8 | caspase 8 | 0.010 | Mouse |