IMP

Process View

Mus musculus

9 genes annotated in mouse

glucocorticoid metabolic process

The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glucocorticoid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glucocorticoid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Dmgdh	dimethylglycine dehydrogenase precursor	0.640
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.483
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.469	Mouse
Apoa1	apolipoprotein A-I	0.424
Ahsg	alpha-2-HS-glycoprotein	0.390
Apoe	apolipoprotein E	0.347	Mouse
Apoc4	apolipoprotein C-IV	0.307
Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C	0.303	Mouse
Mc2r	melanocortin 2 receptor	0.229
Agtr1a	angiotensin II receptor, type 1a	0.225
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.200	Mouse
Apoa2	apolipoprotein A-II	0.198
Npc1	Niemann Pick type C1	0.161
Kl	klotho	0.129
Slc12a1	solute carrier family 12, member 1	0.123
Apob	apolipoprotein B	0.117
Ren1	renin 1 structural	0.115
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.108
Wnk4	WNK lysine deficient protein kinase 4	0.103
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.096	Mouse
Clstn1	calsyntenin 1	0.092
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.092
Aldob	aldolase B, fructose-bisphosphate	0.087
Fga	fibrinogen alpha chain	0.081
Tdo2	tryptophan 2,3-dioxygenase	0.080
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.077
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.064	Mouse
Pde8b	phosphodiesterase 8B	0.062
Tgfbr2	transforming growth factor, beta receptor II	0.062
F2	coagulation factor II	0.058
Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	0.057	Mouse
Gcgr	glucagon receptor	0.055
Lrp1	low density lipoprotein receptor-related protein 1	0.055
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.053
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.053
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.052
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.052
Fgg	fibrinogen gamma chain	0.051
Runx2	runt related transcription factor 2	0.049
Pzp	pregnancy zone protein	0.045
Hamp	hepcidin antimicrobial peptide	0.044
F12	coagulation factor XII (Hageman factor)	0.043
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.043
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.043	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.042
Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	0.042	Mouse
Cdhr5	cadherin-related family member 5	0.042
Fgfr3	fibroblast growth factor receptor 3	0.041
Igfbp1	insulin-like growth factor binding protein 1	0.039
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.039
Hnf4a	hepatic nuclear factor 4, alpha	0.038
Tgfb1	transforming growth factor, beta 1	0.037
C3	complement component 3	0.036
Egfr	epidermal growth factor receptor	0.035
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.034
Lep	leptin	0.033
Ar	androgen receptor	0.032
F9	coagulation factor IX	0.032
Lepr	leptin receptor	0.032
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.031
Gpr50	G-protein-coupled receptor 50	0.031
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.031
Alb	albumin	0.030
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.030
Apoh	apolipoprotein H	0.029
Apoc3	apolipoprotein C-III	0.029
Hpx	hemopexin	0.028
Prlr	prolactin receptor	0.028
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.026
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.026
Rdh7	retinol dehydrogenase 7	0.026
Esr1	estrogen receptor 1 (alpha)	0.026
Sox9	SRY-box containing gene 9	0.025
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.024
Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A	0.023	Mouse
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.023
Inhbc	inhibin beta-C	0.022
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.022
Apcs	serum amyloid P-component	0.022
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.021
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.021	Mouse
Vav2	vav 2 oncogene	0.020
Gc	group specific component	0.020
Hsd3b4	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4	0.020
Htt	huntingtin	0.020
Afm	afamin	0.020
Tshr	thyroid stimulating hormone receptor	0.020
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.020
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.020
Angptl4	angiopoietin-like 4	0.020
Mup3	major urinary protein 3	0.020
Mrap	melanocortin 2 receptor accessory protein	0.020
Plg	plasminogen	0.019
Cp	ceruloplasmin	0.019
Apof	apolipoprotein F	0.019
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2	0.019
Wwox	WW domain-containing oxidoreductase	0.019
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.019
Akr1c6	aldo-keto reductase family 1, member C6	0.019
Mat1a	methionine adenosyltransferase I, alpha	0.019
Ces3a	carboxylesterase 3A	0.019
Gpr182	G protein-coupled receptor 182	0.018
Pomc	pro-opiomelanocortin-alpha	0.018
Pparg	peroxisome proliferator activated receptor gamma	0.018
Lox	lysyl oxidase	0.018
Cyp11b2	cytochrome P450, family 11, subfamily b, polypeptide 2	0.017	Human Zebrafish Mouse Rat
Osmr	oncostatin M receptor	0.017
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.017
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.017
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.017
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.017
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.017
a	nonagouti	0.016
Lect2	leukocyte cell-derived chemotaxin 2	0.016
Orm3	orosomucoid 3	0.016
Hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.016
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.016
Slc23a2	solute carrier family 23 (nucleobase transporters), member 2	0.016
Mup4	major urinary protein 4	0.016
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.016
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.016
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.016
Prnp	prion protein	0.016
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.016
Spry4	sprouty homolog 4 (Drosophila)	0.016
C9	complement component 9	0.015
Prm3	protamine 3	0.015
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.015	Mouse
Thpo	thrombopoietin	0.015
Kiss1	KiSS-1 metastasis-suppressor	0.015
Azgp1	alpha-2-glycoprotein 1, zinc	0.015
Umod	uromodulin	0.015
Tpsb2	tryptase beta 2	0.015
Cps1	carbamoyl-phosphate synthetase 1	0.015
Alx3	aristaless-like homeobox 3	0.015
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.014	Mouse
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.014
Aqp7	aquaporin 7	0.014
G6pc	glucose-6-phosphatase, catalytic	0.014
Il1r1	interleukin 1 receptor, type I	0.014
Klf15	Kruppel-like factor 15	0.014
Pah	phenylalanine hydroxylase	0.014
Hand1	heart and neural crest derivatives expressed transcript 1	0.014
Gml	GPI anchored molecule like protein	0.014
Cyp2d12	cytochrome P450, family 2, subfamily d, polypeptide 12	0.014
Ces1c	carboxylesterase 1C	0.014
Cidec	cell death-inducing DFFA-like effector c	0.013
Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	0.013	Mouse
Hrg	histidine-rich glycoprotein	0.013
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.013
F13b	coagulation factor XIII, beta subunit	0.012
Aadat	aminoadipate aminotransferase	0.012
Cfh	complement component factor h	0.012
Kng1	kininogen 1	0.012
Hgd	homogentisate 1, 2-dioxygenase	0.012
Wfdc12	WAP four-disulfide core domain 12	0.012
Fmo5	flavin containing monooxygenase 5	0.012
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.012
Npy1r	neuropeptide Y receptor Y1	0.012
Ang2	angiogenin, ribonuclease A family, member 2	0.012
Tbx15	T-box 15	0.012
Apoc1	apolipoprotein C-I	0.012
Serpina5	serine (or cysteine) peptidase inhibitor, clade A, member 5	0.012	Mouse
Cckbr	cholecystokinin B receptor	0.012
Cel	carboxyl ester lipase	0.011
Vamp2	vesicle-associated membrane protein 2	0.011
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.011
Apom	apolipoprotein M	0.011
Hoxc5	homeobox C5	0.011
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.011	Mouse
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.011
Ccbp2	chemokine binding protein 2	0.011
Obox2	oocyte specific homeobox 2	0.011
Ctrb1	chymotrypsinogen B1	0.011
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.011
Saa1	serum amyloid A 1	0.011
Prr15	proline rich 15	0.011
Ambp	alpha 1 microglobulin/bikunin	0.011
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.011
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.011
Acvr1	activin A receptor, type 1	0.011
App	amyloid beta (A4) precursor protein	0.011
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.010
Crh	corticotropin releasing hormone	0.010
Ldlr	low density lipoprotein receptor	0.010
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.010	Mouse
Sprr1b	small proline-rich protein 1B	0.010
Star	steroidogenic acute regulatory protein	0.010
Hoxa10	homeobox A10	0.010