IMP

Process View

Mus musculus

4 genes annotated in mouse

positive regulation of intracellular estrogen receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of intracellular estrogen receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of intracellular estrogen receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Esr1	estrogen receptor 1 (alpha)	0.998
Ar	androgen receptor	0.891
Bglap	bone gamma carboxyglutamate protein	0.853
Ghr	growth hormone receptor	0.849
Pax8	paired box gene 8	0.826
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.802	Mouse
Pten	phosphatase and tensin homolog	0.761
Hnrnph1	heterogeneous nuclear ribonucleoprotein H1	0.731
Amhr2	anti-Mullerian hormone type 2 receptor	0.705
Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1	0.612
Kiss1	KiSS-1 metastasis-suppressor	0.542
Hnrnpk	heterogeneous nuclear ribonucleoprotein K	0.538
Lep	leptin	0.481
Duox2	dual oxidase 2	0.459
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.406
Drd2	dopamine receptor D2	0.356
Kiss1r	KISS1 receptor	0.353
Lepr	leptin receptor	0.298
Prlr	prolactin receptor	0.257
Ythdc1	YTH domain containing 1	0.207
Ddx17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.188	Human
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.184
Foxf2	forkhead box F2	0.183
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.179
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.167
Inha	inhibin alpha	0.164
Ahr	aryl-hydrocarbon receptor	0.152
Rac1	RAS-related C3 botulinum substrate 1	0.150
Fshr	follicle stimulating hormone receptor	0.145
Gnrhr	gonadotropin releasing hormone receptor	0.125
Hnrnpr	heterogeneous nuclear ribonucleoprotein R	0.104
Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	0.091
Wsb1	WD repeat and SOCS box-containing 1	0.090
Ncoa6	nuclear receptor coactivator 6	0.085
Zfp326	zinc finger protein 326	0.082
Matr3	matrin 3	0.078
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.078	Human
Thrb	thyroid hormone receptor beta	0.077
Gnrh1	gonadotropin releasing hormone 1	0.076
Prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	0.068
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.061
Myf5	myogenic factor 5	0.058
Pgr	progesterone receptor	0.056
BC018507	cDNA sequence BC018507	0.055
Kit	kit oncogene	0.054
Hoxa10	homeobox A10	0.053
Inhba	inhibin beta-A	0.049
Smad1	MAD homolog 1 (Drosophila)	0.048
Srsf1	serine/arginine-rich splicing factor 1	0.048
Srsf11	serine/arginine-rich splicing factor 11	0.045
Fbxo11	F-box protein 11	0.045
Esr2	estrogen receptor 2 (beta)	0.040
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.039
Egr1	early growth response 1	0.038
Bcl2	B-cell leukemia/lymphoma 2	0.038
Cga	glycoprotein hormones, alpha subunit	0.038
Hnrpdl	heterogeneous nuclear ribonucleoprotein D-like	0.038
Hnrnph3	heterogeneous nuclear ribonucleoprotein H3	0.036
Npc1	Niemann Pick type C1	0.034
Retn	resistin	0.034
Thra	thyroid hormone receptor alpha	0.033
Srsf6	serine/arginine-rich splicing factor 6	0.032
Srsf7	serine/arginine-rich splicing factor 7	0.031
E2f1	E2F transcription factor 1	0.030
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.030
C78704	expressed sequence C78704	0.030
Plekha5	pleckstrin homology domain containing, family A member 5	0.030
Mat2a	methionine adenosyltransferase II, alpha	0.029
Ptgfr	prostaglandin F receptor	0.029
Rnf145	ring finger protein 145	0.029
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.029
Pitx2	paired-like homeodomain transcription factor 2	0.028
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.028
Atxn1	ataxin 1	0.028
Paxip1	PAX interacting (with transcription-activation domain) protein 1	0.028
Cldn8	claudin 8	0.028
Gcfc1	GC-rich sequence DNA-binding factor 1	0.028
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.027
Hnrnph2	heterogeneous nuclear ribonucleoprotein H2	0.027
Gata5	GATA binding protein 5	0.026
Ube2d2	ubiquitin-conjugating enzyme E2D 2	0.026
Ubp1	upstream binding protein 1	0.025
Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.025
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.025
Tshr	thyroid stimulating hormone receptor	0.024	Mouse
Ivns1abp	influenza virus NS1A binding protein	0.022
Gata6	GATA binding protein 6	0.022
Zfp185	zinc finger protein 185	0.022
Tia1	cytotoxic granule-associated RNA binding protein 1	0.022
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.022
Ctnnb1	catenin (cadherin associated protein), beta 1	0.022
Wwox	WW domain-containing oxidoreductase	0.021
Cdh1	cadherin 1	0.021
Hnrnpa3	heterogeneous nuclear ribonucleoprotein A3	0.021
Gata3	GATA binding protein 3	0.021
Rbbp6	retinoblastoma binding protein 6	0.021
Srsf5	serine/arginine-rich splicing factor 5	0.021
C78891	expressed sequence C78891	0.021
Irs2	insulin receptor substrate 2	0.021
Luc7l3	LUC7-like 3 (S. cerevisiae)	0.021
Ncoa3	nuclear receptor coactivator 3	0.021
Cnot2	CCR4-NOT transcription complex, subunit 2	0.020
Cenpc1	centromere protein C1	0.020
Cav1	caveolin 1, caveolae protein	0.019
Igf1	insulin-like growth factor 1	0.019
Foxc1	forkhead box C1	0.019
Tlr5	toll-like receptor 5	0.019
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.018
Insr	insulin receptor	0.018
Brca2	breast cancer 2	0.018
Ogt	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.018
Fam13b	family with sequence similarity 13, member B	0.017
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.017
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.017
Klf5	Kruppel-like factor 5	0.017
Eif4g2	eukaryotic translation initiation factor 4, gamma 2	0.017
Hnrnpm	heterogeneous nuclear ribonucleoprotein M	0.017
Fgf10	fibroblast growth factor 10	0.017
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.017
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.017
Wdr82	WD repeat domain containing 82	0.017
Invs	inversin	0.016
Bglap2	bone gamma-carboxyglutamate protein 2	0.016
Gja1	gap junction protein, alpha 1	0.016
Ncam2	neural cell adhesion molecule 2	0.016
Nhlh2	nescient helix loop helix 2	0.016
Vgf	VGF nerve growth factor inducible	0.016
Rad21	RAD21 homolog (S. pombe)	0.015
Vdr	vitamin D receptor	0.015
Ccnl2	cyclin L2	0.015
Fst	follistatin	0.014
Alms1	Alstrom syndrome 1 homolog (human)	0.014
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.014
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.014
Lbr	lamin B receptor	0.013
Zfp398	zinc finger protein 398	0.013
Fubp3	far upstream element (FUSE) binding protein 3	0.013
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.013
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.013
Rev3l	REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)	0.013
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.013	Mouse
Ctbp2	C-terminal binding protein 2	0.013
Sf3b1	splicing factor 3b, subunit 1	0.013
Btg1	B-cell translocation gene 1, anti-proliferative	0.013
Foxo3	forkhead box O3	0.013
Dido1	death inducer-obliterator 1	0.013
Tead1	TEA domain family member 1	0.013
Fgfr2	fibroblast growth factor receptor 2	0.013
Trp53bp1	transformation related protein 53 binding protein 1	0.012
Lrrc26	leucine rich repeat containing 26	0.012
Hp1bp3	heterochromatin protein 1, binding protein 3	0.012
Star	steroidogenic acute regulatory protein	0.012
Cldn3	claudin 3	0.012
Smr2	submaxillary gland androgen regulated protein 2	0.012
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.012
Sfrp4	secreted frizzled-related protein 4	0.012
Hdac2	histone deacetylase 2	0.012
Chad	chondroadherin	0.012
Smad4	MAD homolog 4 (Drosophila)	0.012
Qser1	glutamine and serine rich 1	0.012
Esyt3	extended synaptotagmin-like protein 3	0.012
Tmprss2	transmembrane protease, serine 2	0.012
Rfx3	regulatory factor X, 3 (influences HLA class II expression)	0.012
Tg	thyroglobulin	0.012
Npr1	natriuretic peptide receptor 1	0.012
Rpgrip1l	Rpgrip1-like	0.011
Nos3	nitric oxide synthase 3, endothelial cell	0.011
Zmynd11	zinc finger, MYND domain containing 11	0.011
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.011
Spo11	sporulation protein, meiosis-specific, SPO11 homolog (S. cerevisiae)	0.011
Kdm2b	lysine (K)-specific demethylase 2B	0.011
Apc	adenomatosis polyposis coli	0.011
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.011
Lrrc58	leucine rich repeat containing 58	0.011
Sult5a1	sulfotransferase family 5A, member 1	0.011
Mms22l	MMS22-like, DNA repair protein	0.011
Fubp1	far upstream element (FUSE) binding protein 1	0.011
Cul4a	cullin 4A	0.011
Bnc1	basonuclin 1	0.011
Esrrb	estrogen related receptor, beta	0.011
Vmn2r1	vomeronasal 2, receptor 1	0.011
Pax2	paired box gene 2	0.011
Tra2a	transformer 2 alpha homolog (Drosophila)	0.010
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.010
6720463M24Rik	RIKEN cDNA 6720463M24 gene	0.010
Nxf1	nuclear RNA export factor 1 homolog (S. cerevisiae)	0.010
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.010
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.010
Tmem30b	transmembrane protein 30B	0.010
Tubgcp3	tubulin, gamma complex associated protein 3	0.010