IMP

Process View

Mus musculus

9 genes annotated in mouse

positive regulation of metanephros development

Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of metanephros development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of metanephros development" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	0.998
Ret	ret proto-oncogene	0.949
Vegfa	vascular endothelial growth factor A	0.791
Fbn1	fibrillin 1	0.577
C1qb	complement component 1, q subcomponent, beta polypeptide	0.573	Mouse
Nos3	nitric oxide synthase 3, endothelial cell	0.508
Bcl2	B-cell leukemia/lymphoma 2	0.448
Wt1	Wilms tumor 1 homolog	0.434
C1qc	complement component 1, q subcomponent, C chain	0.409	Mouse
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.408	Mouse
Lhx1	LIM homeobox protein 1	0.358
Tgfbr2	transforming growth factor, beta receptor II	0.323
Foxc2	forkhead box C2	0.277
Msx1	homeobox, msh-like 1	0.264
Apoe	apolipoprotein E	0.261
Ptgs2	prostaglandin-endoperoxide synthase 2	0.210
Fgfr2	fibroblast growth factor receptor 2	0.207
Emx2	empty spiracles homolog 2 (Drosophila)	0.198
Rara	retinoic acid receptor, alpha	0.191
Pax3	paired box gene 3	0.190
Shh	sonic hedgehog	0.188
Ldlr	low density lipoprotein receptor	0.162
Jag1	jagged 1	0.155
Nab2	Ngfi-A binding protein 2	0.143
Hoxa1	homeobox A1	0.142
Tyrobp	TYRO protein tyrosine kinase binding protein	0.126
Phox2b	paired-like homeobox 2b	0.113
Tbx1	T-box 1	0.110
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.090
Rarg	retinoic acid receptor, gamma	0.088
Fgf10	fibroblast growth factor 10	0.086
Gbx2	gastrulation brain homeobox 2	0.082
Gdnf	glial cell line derived neurotrophic factor	0.078
Csf1	colony stimulating factor 1 (macrophage)	0.078
Lmx1a	LIM homeobox transcription factor 1 alpha	0.073
Trp53	transformation related protein 53	0.066
Sox10	SRY-box containing gene 10	0.063
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.062
Eya1	eyes absent 1 homolog (Drosophila)	0.054
Gucy2e	guanylate cyclase 2e	0.053
Wnt9b	wingless-type MMTV integration site 9B	0.051
Rarb	retinoic acid receptor, beta	0.050
Ren1	renin 1 structural	0.050
Lama5	laminin, alpha 5	0.046
Foxc1	forkhead box C1	0.041
Agtr1a	angiotensin II receptor, type 1a	0.039	Mouse
Egr2	early growth response 2	0.039	Mouse
Tgfb1	transforming growth factor, beta 1	0.038
Otx1	orthodenticle homolog 1 (Drosophila)	0.035
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.032
Ctss	cathepsin S	0.032
Ly86	lymphocyte antigen 86	0.031
Wnt4	wingless-related MMTV integration site 4	0.031
Notch2	Notch gene homolog 2 (Drosophila)	0.030
Hoxa3	homeobox A3	0.030
Hoxa11	homeobox A11	0.028
Rxra	retinoid X receptor alpha	0.028
Lhx9	LIM homeobox protein 9	0.027
Bdkrb2	bradykinin receptor, beta 2	0.026	Mouse
Lef1	lymphoid enhancer binding factor 1	0.026
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.026
Lepr	leptin receptor	0.023
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.023
Isl1	ISL1 transcription factor, LIM/homeodomain	0.022
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.022
Src	Rous sarcoma oncogene	0.022
Fgf8	fibroblast growth factor 8	0.021
Fgf3	fibroblast growth factor 3	0.021
Hoxb3	homeobox B3	0.021
Fgfr1	fibroblast growth factor receptor 1	0.020
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.020
Bmp4	bone morphogenetic protein 4	0.020
Meox2	mesenchyme homeobox 2	0.019
Egr1	early growth response 1	0.019	Mouse Rat
Pdgfb	platelet derived growth factor, B polypeptide	0.018	Human
Hoxd11	homeobox D11	0.018
Osr1	odd-skipped related 1 (Drosophila)	0.018
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.017
Sox18	SRY-box containing gene 18	0.017
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.017
Hic1	hypermethylated in cancer 1	0.017
Foxd2	forkhead box D2	0.017
Msx2	homeobox, msh-like 2	0.017
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.016
Hand1	heart and neural crest derivatives expressed transcript 1	0.016
Hmx3	H6 homeobox 3	0.016
Kdr	kinase insert domain protein receptor	0.016	Mouse
Gata3	GATA binding protein 3	0.016
Gli3	GLI-Kruppel family member GLI3	0.016
Pou4f2	POU domain, class 4, transcription factor 2	0.015
Fos	FBJ osteosarcoma oncogene	0.015
Ptprb	protein tyrosine phosphatase, receptor type, B	0.015
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.015
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.015
Agtrap	angiotensin II, type I receptor-associated protein	0.015
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.014
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.014
Bmp2	bone morphogenetic protein 2	0.013
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.013
Zeb1	zinc finger E-box binding homeobox 1	0.013
Agtr2	angiotensin II receptor, type 2	0.013
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.013
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.013
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.012
Kiss1	KiSS-1 metastasis-suppressor	0.012
Igl	immunoglobulin lambda chain complex	0.012
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.012
Aif1	allograft inflammatory factor 1	0.012
Max	Max protein	0.011
Cdh5	cadherin 5	0.011
Dlx5	distal-less homeobox 5	0.011
Itga3	integrin alpha 3	0.011
Tcfap2a	transcription factor AP-2, alpha	0.011
Csf3	colony stimulating factor 3 (granulocyte)	0.011
Foxg1	forkhead box G1	0.011
Flt4	FMS-like tyrosine kinase 4	0.011	Mouse
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.011
Tcf21	transcription factor 21	0.011
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.011
Thrb	thyroid hormone receptor beta	0.011
Otx2	orthodenticle homolog 2 (Drosophila)	0.011
Sox4	SRY-box containing gene 4	0.010
Gab2	growth factor receptor bound protein 2-associated protein 2	0.010
Nog	noggin	0.010
Nos2	nitric oxide synthase 2, inducible	0.010
Phox2a	paired-like homeobox 2a	0.010