IMP

Process View

Mus musculus

3 genes annotated in mouse

Multi-species View

negative regulation of hypersensitivity

GO:0002884

Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of hypersensitivity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of hypersensitivity" (in gray)

Name	Description	Probability	Func Analog Organism
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.939
Lyz2	lysozyme 2	0.721
C1qb	complement component 1, q subcomponent, beta polypeptide	0.474
Tyrobp	TYRO protein tyrosine kinase binding protein	0.393
Cd19	CD19 antigen	0.351
Ptprc	protein tyrosine phosphatase, receptor type, C	0.351
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.248
Ifngr1	interferon gamma receptor 1	0.232
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.222
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.222
Ctss	cathepsin S	0.213
C1qc	complement component 1, q subcomponent, C chain	0.210
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.181
Mpeg1	macrophage expressed gene 1	0.172
Ccr1	chemokine (C-C motif) receptor 1	0.166
Aif1	allograft inflammatory factor 1	0.161
C3ar1	complement component 3a receptor 1	0.150
Clec4n	C-type lectin domain family 4, member n	0.147
Ly86	lymphocyte antigen 86	0.144
Msr1	macrophage scavenger receptor 1	0.141
Ccl9	chemokine (C-C motif) ligand 9	0.120
Csf1r	colony stimulating factor 1 receptor	0.120
Mrc1	mannose receptor, C type 1	0.096
Ccl6	chemokine (C-C motif) ligand 6	0.078
AF251705	cDNA sequence AF251705	0.074
Prf1	perforin 1 (pore forming protein)	0.071
Cd14	CD14 antigen	0.069
Apoe	apolipoprotein E	0.068
Cybb	cytochrome b-245, beta polypeptide	0.067
Cfh	complement component factor h	0.061
Cd68	CD68 antigen	0.055
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.053
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.053
Lyz1	lysozyme 1	0.052
Hck	hemopoietic cell kinase	0.048
Fasl	Fas ligand (TNF superfamily, member 6)	0.046
Clec4d	C-type lectin domain family 4, member d	0.045
Il1b	interleukin 1 beta	0.044
Cd86	CD86 antigen	0.042
Cxcr2	chemokine (C-X-C motif) receptor 2	0.041
Ifitm6	interferon induced transmembrane protein 6	0.041
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.040
Traf3ip2	TRAF3 interacting protein 2	0.037
Tlr4	toll-like receptor 4	0.037
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.036
Cd180	CD180 antigen	0.035
Ctsc	cathepsin C	0.034
Tbxas1	thromboxane A synthase 1, platelet	0.034
Clec4a2	C-type lectin domain family 4, member a2	0.033
C3	complement component 3	0.032
Cd53	CD53 antigen	0.032
C5ar1	complement component 5a receptor 1	0.031
Clec7a	C-type lectin domain family 7, member a	0.030
Fpr2	formyl peptide receptor 2	0.030
Itgam	integrin alpha M	0.029
Ccl12	chemokine (C-C motif) ligand 12	0.029
Ccr5	chemokine (C-C motif) receptor 5	0.028
Ccr2	chemokine (C-C motif) receptor 2	0.027
Myd88	myeloid differentiation primary response gene 88	0.027
Fcna	ficolin A	0.027
Fcgr3	Fc receptor, IgG, low affinity III	0.026	Mouse
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.026
Fcgr4	Fc receptor, IgG, low affinity IV	0.026
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.026
Vcam1	vascular cell adhesion molecule 1	0.025
Tnip1	TNFAIP3 interacting protein 1	0.024
Lair1	leukocyte-associated Ig-like receptor 1	0.024
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.024
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.023
Casp1	caspase 1	0.022
Selp	selectin, platelet	0.022
Tlr7	toll-like receptor 7	0.022
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.022
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.022
Sfpi1	SFFV proviral integration 1	0.021
Ifnar2	interferon (alpha and beta) receptor 2	0.021
Plek	pleckstrin	0.021
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.020
Trem3	triggering receptor expressed on myeloid cells 3	0.020
Il10	interleukin 10	0.020
Srgn	serglycin	0.020
Itgb2	integrin beta 2	0.020
Sell	selectin, lymphocyte	0.019
Unc93b1	unc-93 homolog B1 (C. elegans)	0.019
Zg16	zymogen granule protein 16	0.019
Ccl3	chemokine (C-C motif) ligand 3	0.019
Mmp8	matrix metallopeptidase 8	0.019
Cxcl13	chemokine (C-X-C motif) ligand 13	0.018
Ccr3	chemokine (C-C motif) receptor 3	0.017
AI607873	expressed sequence AI607873	0.017
Aoah	acyloxyacyl hydrolase	0.017
Fyb	FYN binding protein	0.017
Ifng	interferon gamma	0.016
Il12a	interleukin 12a	0.016
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.016
Fpr1	formyl peptide receptor 1	0.015
Tg	thyroglobulin	0.015
Ctsh	cathepsin H	0.015
Gp1ba	glycoprotein 1b, alpha polypeptide	0.015
Lcn4	lipocalin 4	0.015
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.015
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.015
Tlr2	toll-like receptor 2	0.014
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.014
Ticam1	toll-like receptor adaptor molecule 1	0.014
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.014
Clec4e	C-type lectin domain family 4, member e	0.014
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.014
Mpl	myeloproliferative leukemia virus oncogene	0.013
Il18rap	interleukin 18 receptor accessory protein	0.013
Pf4	platelet factor 4	0.013
Igsf6	immunoglobulin superfamily, member 6	0.013
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.013
Cr2	complement receptor 2	0.012
Jak1	Janus kinase 1	0.012
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.012
Inpp5d	inositol polyphosphate-5-phosphatase D	0.012
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.012
Ncf4	neutrophil cytosolic factor 4	0.012
Gm11428	predicted gene 11428	0.012
Mefv	Mediterranean fever	0.012
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.012
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.012
Hmox1	heme oxygenase (decycling) 1	0.011
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.011
Cfp	complement factor properdin	0.011
Gp5	glycoprotein 5 (platelet)	0.011
Ccr7	chemokine (C-C motif) receptor 7	0.011
Prg2	proteoglycan 2, bone marrow	0.011
Folr2	folate receptor 2 (fetal)	0.011
Lgmn	legumain	0.010
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.010
Il18	interleukin 18	0.010
Tmem106a	transmembrane protein 106A	0.010
Marco	macrophage receptor with collagenous structure	0.010
Lpxn	leupaxin	0.010