IMP

Process View

Mus musculus

11 genes annotated in mouse

Multi-species View

vascular smooth muscle cell differentiation

GO:0035886

The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "vascular smooth muscle cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "vascular smooth muscle cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Gata4	GATA binding protein 4	0.992
Notch1	Notch gene homolog 1 (Drosophila)	0.990
Notch2	Notch gene homolog 2 (Drosophila)	0.977	Mouse
Fgf8	fibroblast growth factor 8	0.959
Pitx2	paired-like homeodomain transcription factor 2	0.933
Hand2	heart and neural crest derivatives expressed transcript 2	0.918
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.906
Jag1	jagged 1	0.891
Psen1	presenilin 1	0.744
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.692	Mouse
Zfpm2	zinc finger protein, multitype 2	0.687
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.684
Dmd	dystrophin, muscular dystrophy	0.539
Flt4	FMS-like tyrosine kinase 4	0.483
Nos3	nitric oxide synthase 3, endothelial cell	0.460
Tbx4	T-box 4	0.447
Emx1	empty spiracles homolog 1 (Drosophila)	0.443
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.430
Dll1	delta-like 1 (Drosophila)	0.414
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.369
Rxra	retinoid X receptor alpha	0.318
Chd7	chromodomain helicase DNA binding protein 7	0.318
Hes1	hairy and enhancer of split 1 (Drosophila)	0.305
Tbx3	T-box 3	0.298
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.259
Foxc1	forkhead box C1	0.249
Lama5	laminin, alpha 5	0.241
Hoxa13	homeobox A13	0.208
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.201
Smad6	MAD homolog 6 (Drosophila)	0.195
Mesp1	mesoderm posterior 1	0.191	Human
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.170
Egfl7	EGF-like domain 7	0.169
Arid1b	AT rich interactive domain 1B (SWI-like)	0.160
Col4a2	collagen, type IV, alpha 2	0.143
Psen2	presenilin 2	0.140
Efnb2	ephrin B2	0.129
Vegfa	vascular endothelial growth factor A	0.123
Isl1	ISL1 transcription factor, LIM/homeodomain	0.121
Jag2	jagged 2	0.103
Gata6	GATA binding protein 6	0.102	Human
Pax3	paired box gene 3	0.097
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.094
Shh	sonic hedgehog	0.092
Dll4	delta-like 4 (Drosophila)	0.085
Dag1	dystroglycan 1	0.082
Tbx2	T-box 2	0.081
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.077
Kdr	kinase insert domain protein receptor	0.076
Sox17	SRY-box containing gene 17	0.072
Foxc2	forkhead box C2	0.069
Ntf3	neurotrophin 3	0.066
Hbegf	heparin-binding EGF-like growth factor	0.059
Srebf2	sterol regulatory element binding factor 2	0.058
Rb1	retinoblastoma 1	0.057
Pkd1	polycystic kidney disease 1 homolog	0.054
Myl3	myosin, light polypeptide 3	0.051
Notch3	Notch gene homolog 3 (Drosophila)	0.049	Mouse
Nog	noggin	0.048
She	src homology 2 domain-containing transforming protein E	0.046
Heyl	hairy/enhancer-of-split related with YRPW motif-like	0.046	Mouse
Adm	adrenomedullin	0.042
Sox2	SRY-box containing gene 2	0.038
Sox18	SRY-box containing gene 18	0.036
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.036
Smarcd3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.034
Cd247	CD247 antigen	0.033
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.033
Foxg1	forkhead box G1	0.032
Gsc	goosecoid homeobox	0.032
Zfp503	zinc finger protein 503	0.032
Efnb1	ephrin B1	0.031
Bmp4	bone morphogenetic protein 4	0.031
Cdh5	cadherin 5	0.030
Flt1	FMS-like tyrosine kinase 1	0.030
Sox13	SRY-box containing gene 13	0.029
Rasl12	RAS-like, family 12	0.029
Ptov1	prostate tumor over expressed gene 1	0.029
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.029
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.026
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.025
Ramp2	receptor (calcitonin) activity modifying protein 2	0.025
Ptk2	PTK2 protein tyrosine kinase 2	0.025
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.025
Lmx1b	LIM homeobox transcription factor 1 beta	0.025
Fkrp	fukutin related protein	0.025
Ednra	endothelin receptor type A	0.024
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.024
Asb16	ankyrin repeat and SOCS box-containing 16	0.024
Snai1	snail homolog 1 (Drosophila)	0.023
Otx1	orthodenticle homolog 1 (Drosophila)	0.022
Calcrl	calcitonin receptor-like	0.022
Sox7	SRY-box containing gene 7	0.021
Epha3	Eph receptor A3	0.020
Hes5	hairy and enhancer of split 5 (Drosophila)	0.020	Mouse
Eng	endoglin	0.019
Emx2	empty spiracles homolog 2 (Drosophila)	0.019
Dmpk	dystrophia myotonica-protein kinase	0.019
Tcf15	transcription factor 15	0.018
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.018
Tcf21	transcription factor 21	0.016
Lama2	laminin, alpha 2	0.016
Lox	lysyl oxidase	0.016
Kank3	KN motif and ankyrin repeat domains 3	0.016
Tgfb2	transforming growth factor, beta 2	0.016
Pam	peptidylglycine alpha-amidating monooxygenase	0.015
Npr1	natriuretic peptide receptor 1	0.015
Lamb2	laminin, beta 2	0.015
Hic1	hypermethylated in cancer 1	0.015
Tbx1	T-box 1	0.015
Tbx5	T-box 5	0.015
Pdgfc	platelet-derived growth factor, C polypeptide	0.015
Efna1	ephrin A1	0.015
Homer3	homer homolog 3 (Drosophila)	0.014
Gaa	glucosidase, alpha, acid	0.014
Egln1	EGL nine homolog 1 (C. elegans)	0.013
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.013
Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.013
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.013
Smtn	smoothelin	0.013
Tnnt3	troponin T3, skeletal, fast	0.013
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.013	Mouse
Phldb1	pleckstrin homology-like domain, family B, member 1	0.013
Otx2	orthodenticle homolog 2 (Drosophila)	0.013
Sufu	suppressor of fused homolog (Drosophila)	0.013
Gja4	gap junction protein, alpha 4	0.012
Sgcb	sarcoglycan, beta (dystrophin-associated glycoprotein)	0.012
Zfp651	zinc finger protein 651	0.012
Rbms2	RNA binding motif, single stranded interacting protein 2	0.012
Smarcc2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.011
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.011
Xirp1	xin actin-binding repeat containing 1	0.011
Akr7a5	aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase)	0.011
Ripply3	ripply3 homolog (zebrafish)	0.011
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.011
Cxcr7	chemokine (C-X-C motif) receptor 7	0.011
Etv2	ets variant gene 2	0.010
Tead2	TEA domain family member 2	0.010
Lrp5	low density lipoprotein receptor-related protein 5	0.010
Bmp6	bone morphogenetic protein 6	0.010
Bcl6b	B-cell CLL/lymphoma 6, member B	0.010
Fgf15	fibroblast growth factor 15	0.010
Pax6	paired box gene 6	0.010