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Mus musculus

1 genes annotated in mouse

glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

GO:2000701

The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation" (in gray)

Name	Description	Probability	Func Analog Organism
Gata4	GATA binding protein 4	1.000	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.998
Gata6	GATA binding protein 6	0.988	Mouse
Jag1	jagged 1	0.976
Pitx2	paired-like homeodomain transcription factor 2	0.972
Rxra	retinoid X receptor alpha	0.971
Fgf8	fibroblast growth factor 8	0.945
Bmp4	bone morphogenetic protein 4	0.905
Hoxa1	homeobox A1	0.851
Hand2	heart and neural crest derivatives expressed transcript 2	0.850
Shh	sonic hedgehog	0.847
Tgfb2	transforming growth factor, beta 2	0.846
Vegfa	vascular endothelial growth factor A	0.846
Fgfr2	fibroblast growth factor receptor 2	0.798
Foxc2	forkhead box C2	0.747
Pax2	paired box gene 2	0.688
Tbx1	T-box 1	0.628
Zfpm2	zinc finger protein, multitype 2	0.613
Gli3	GLI-Kruppel family member GLI3	0.499
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.479
Pax3	paired box gene 3	0.459
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.429
Foxc1	forkhead box C1	0.416
Tbx3	T-box 3	0.378
Mesp1	mesoderm posterior 1	0.340
Rarg	retinoic acid receptor, gamma	0.329
Nos3	nitric oxide synthase 3, endothelial cell	0.316
Isl1	ISL1 transcription factor, LIM/homeodomain	0.279
Tead3	TEA domain family member 3	0.261
Hand1	heart and neural crest derivatives expressed transcript 1	0.252
Efnb2	ephrin B2	0.245
Chd7	chromodomain helicase DNA binding protein 7	0.241
Klf3	Kruppel-like factor 3 (basic)	0.234
Sox9	SRY-box containing gene 9	0.234
Gata5	GATA binding protein 5	0.228	Mouse
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.197
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.194
Ntf3	neurotrophin 3	0.193
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.190
Smad6	MAD homolog 6 (Drosophila)	0.168
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.154
Fgf10	fibroblast growth factor 10	0.149
Eya1	eyes absent 1 homolog (Drosophila)	0.134
Foxf1a	forkhead box F1a	0.125
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.122
Wt1	Wilms tumor 1 homolog	0.102
Egfr	epidermal growth factor receptor	0.099
Sox4	SRY-box containing gene 4	0.093
Notch1	Notch gene homolog 1 (Drosophila)	0.093
Tcfap2a	transcription factor AP-2, alpha	0.092
Tbx2	T-box 2	0.081
Acvr1	activin A receptor, type 1	0.072
Tal1	T-cell acute lymphocytic leukemia 1	0.069
Sox7	SRY-box containing gene 7	0.063
Ppara	peroxisome proliferator activated receptor alpha	0.062
Meox2	mesenchyme homeobox 2	0.061
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.059
Bnc1	basonuclin 1	0.059
Rarb	retinoic acid receptor, beta	0.050
Msx1	homeobox, msh-like 1	0.048
Ece1	endothelin converting enzyme 1	0.046
Snai1	snail homolog 1 (Drosophila)	0.046
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.045
Tcf21	transcription factor 21	0.040
Efnb1	ephrin B1	0.040
Hoxa3	homeobox A3	0.040
Ednra	endothelin receptor type A	0.040
Rara	retinoic acid receptor, alpha	0.039
Smo	smoothened homolog (Drosophila)	0.033
Gbx2	gastrulation brain homeobox 2	0.031
Dll1	delta-like 1 (Drosophila)	0.030
Ihh	Indian hedgehog	0.030
Chrd	chordin	0.030
Hoxb4	homeobox B4	0.029
Gdnf	glial cell line derived neurotrophic factor	0.028
Gli2	GLI-Kruppel family member GLI2	0.028
Hoxb3	homeobox B3	0.026
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.026
Hoxa2	homeobox A2	0.024
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.024
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.024
Vangl2	vang-like 2 (van gogh, Drosophila)	0.024
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.024
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.023
Gpc3	glypican 3	0.023
Lmx1a	LIM homeobox transcription factor 1 alpha	0.023
Bmp7	bone morphogenetic protein 7	0.022
Myl7	myosin, light polypeptide 7, regulatory	0.022
Plac1	placental specific protein 1	0.021
She	src homology 2 domain-containing transforming protein E	0.021
Ar	androgen receptor	0.021
Epha1	Eph receptor A1	0.021
Tgfbr2	transforming growth factor, beta receptor II	0.020
Foxg1	forkhead box G1	0.019
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.019
Pitx1	paired-like homeodomain transcription factor 1	0.019
Gja1	gap junction protein, alpha 1	0.018
Lef1	lymphoid enhancer binding factor 1	0.018
Npr1	natriuretic peptide receptor 1	0.018
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.017
Twist2	twist homolog 2 (Drosophila)	0.017
Axin2	axin2	0.016
Hoxc8	homeobox C8	0.016
Hes1	hairy and enhancer of split 1 (Drosophila)	0.015
Nf1	neurofibromatosis 1	0.015
Adam17	a disintegrin and metallopeptidase domain 17	0.015
Fgf3	fibroblast growth factor 3	0.015
Fgfr1	fibroblast growth factor receptor 1	0.015
Hoxb6	homeobox B6	0.014
Nynrin	NYN domain and retroviral integrase containing	0.014
Tbx20	T-box 20	0.014
Zfpm1	zinc finger protein, multitype 1	0.014
Efna1	ephrin A1	0.014
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.014
Kdr	kinase insert domain protein receptor	0.013
Gata2	GATA binding protein 2	0.013	Mouse
Des	desmin	0.013
Tbx5	T-box 5	0.013
Hoxa13	homeobox A13	0.013
Fgf18	fibroblast growth factor 18	0.012
Zeb1	zinc finger E-box binding homeobox 1	0.012
Prrx2	paired related homeobox 2	0.012
Upk3b	uroplakin 3B	0.012
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.012
Lrp2	low density lipoprotein receptor-related protein 2	0.011
Hoxa4	homeobox A4	0.011
Hic1	hypermethylated in cancer 1	0.011
Ctnnb1	catenin (cadherin associated protein), beta 1	0.011
Sim2	single-minded homolog 2 (Drosophila)	0.011
Wnt6	wingless-related MMTV integration site 6	0.011
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.011
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.011
Fzd8	frizzled homolog 8 (Drosophila)	0.011
Smad3	MAD homolog 3 (Drosophila)	0.011
Smad4	MAD homolog 4 (Drosophila)	0.011
Hoxd13	homeobox D13	0.011
Foxa2	forkhead box A2	0.011
Slc38a5	solute carrier family 38, member 5	0.010
Pcdh12	protocadherin 12	0.010
Hoxb5	homeobox B5	0.010
Fbn2	fibrillin 2	0.010
Tmprss2	transmembrane protease, serine 2	0.010