IMP

Process View

Mus musculus

9 genes annotated in mouse

peripheral nervous system neuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "peripheral nervous system neuron differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "peripheral nervous system neuron differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Pax6	paired box gene 6	0.992
Otx2	orthodenticle homolog 2 (Drosophila)	0.990
Isl1	ISL1 transcription factor, LIM/homeodomain	0.983
Shh	sonic hedgehog	0.942
Gli3	GLI-Kruppel family member GLI3	0.935
Hand2	heart and neural crest derivatives expressed transcript 2	0.903
Sox2	SRY-box containing gene 2	0.888
Neurod1	neurogenic differentiation 1	0.874	Zebrafish Mouse
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.784	Zebrafish
Lhx3	LIM homeobox protein 3	0.755	Mouse
Onecut1	one cut domain, family member 1	0.702	Mouse
Emx1	empty spiracles homolog 1 (Drosophila)	0.665
Pax3	paired box gene 3	0.640
Pax2	paired box gene 2	0.565
Hoxa10	homeobox A10	0.547	Mouse
Lhx5	LIM homeobox protein 5	0.506	Mouse
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.503
Insm1	insulinoma-associated 1	0.492
Pitx2	paired-like homeodomain transcription factor 2	0.475
Emx2	empty spiracles homolog 2 (Drosophila)	0.426
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.422
Foxg1	forkhead box G1	0.415
Eya1	eyes absent 1 homolog (Drosophila)	0.390
Gbx2	gastrulation brain homeobox 2	0.339
Ptf1a	pancreas specific transcription factor, 1a	0.329	Mouse
En1	engrailed 1	0.325
Nhlh1	nescient helix loop helix 1	0.316	Mouse
Chd7	chromodomain helicase DNA binding protein 7	0.316
Hoxd13	homeobox D13	0.306
Ebf3	early B-cell factor 3	0.281
Hoxa13	homeobox A13	0.268
Ntf3	neurotrophin 3	0.257
Pou4f3	POU domain, class 4, transcription factor 3	0.248	Mouse
Msx2	homeobox, msh-like 2	0.238
Hoxd9	homeobox D9	0.218
Lhx1	LIM homeobox protein 1	0.217	Mouse
Sox11	SRY-box containing gene 11	0.211
Gsc	goosecoid homeobox	0.206
Hoxb1	homeobox B1	0.203
Hoxd3	homeobox D3	0.200
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.198
Fgf8	fibroblast growth factor 8	0.195
Gli2	GLI-Kruppel family member GLI2	0.193
Tlr4	toll-like receptor 4	0.177
Lhx9	LIM homeobox protein 9	0.176	Mouse
Tcfap2a	transcription factor AP-2, alpha	0.175
Sall3	sal-like 3 (Drosophila)	0.170
Hoxa1	homeobox A1	0.163
Wt1	Wilms tumor 1 homolog	0.152
Dcc	deleted in colorectal carcinoma	0.142
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.141
Phox2a	paired-like homeobox 2a	0.139
Gdf11	growth differentiation factor 11	0.127
Hoxd11	homeobox D11	0.126
Gdnf	glial cell line derived neurotrophic factor	0.120
Hoxd1	homeobox D1	0.116
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.116
Foxc2	forkhead box C2	0.115
Hoxa9	homeobox A9	0.115	Mouse
Neurog2	neurogenin 2	0.110	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.109	Mouse
Tlx3	T-cell leukemia, homeobox 3	0.105
Bdnf	brain derived neurotrophic factor	0.105
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.092
Myf5	myogenic factor 5	0.090
Sox1	SRY-box containing gene 1	0.086
Hoxa11	homeobox A11	0.086
Otx1	orthodenticle homolog 1 (Drosophila)	0.081
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.081
Uncx	UNC homeobox	0.079
Ina	internexin neuronal intermediate filament protein, alpha	0.079	Mouse
Sox3	SRY-box containing gene 3	0.077
Dlx1	distal-less homeobox 1	0.074
Msx1	homeobox, msh-like 1	0.074
Nkx6-1	NK6 homeobox 1	0.072
Foxc1	forkhead box C1	0.071
Hoxc5	homeobox C5	0.071
Hes5	hairy and enhancer of split 5 (Drosophila)	0.070	Zebrafish
Phox2b	paired-like homeobox 2b	0.070
Atoh1	atonal homolog 1 (Drosophila)	0.069	Zebrafish Mouse
Pou3f2	POU domain, class 3, transcription factor 2	0.068	Mouse
Hoxa4	homeobox A4	0.066
Hoxb9	homeobox B9	0.065	Mouse
Pou3f4	POU domain, class 3, transcription factor 4	0.064	Mouse
Hoxc6	homeobox C6	0.062
Tcfap2c	transcription factor AP-2, gamma	0.061
BC024139	cDNA sequence BC024139	0.061
Emid2	EMI domain containing 2	0.060
Neurog1	neurogenin 1	0.060	Zebrafish Mouse
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.059
Dlx2	distal-less homeobox 2	0.058
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.058
Dab1	disabled homolog 1 (Drosophila)	0.056
Hoxc8	homeobox C8	0.055
Mab21l2	mab-21-like 2 (C. elegans)	0.055
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.053
Sim1	single-minded homolog 1 (Drosophila)	0.053
Prph	peripherin	0.053	Mouse
Efna2	ephrin A2	0.051
Foxd2	forkhead box D2	0.050
Sim2	single-minded homolog 2 (Drosophila)	0.050
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.047
Pbx1	pre B-cell leukemia transcription factor 1	0.046
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.045
Hes1	hairy and enhancer of split 1 (Drosophila)	0.045
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.044
Nrg1	neuregulin 1	0.044
Pou4f2	POU domain, class 4, transcription factor 2	0.044	Mouse
Prrx1	paired related homeobox 1	0.043
Neurod4	neurogenic differentiation 4	0.042	Mouse
Meox2	mesenchyme homeobox 2	0.042
Bnc1	basonuclin 1	0.040
Hoxb7	homeobox B7	0.039
Hand1	heart and neural crest derivatives expressed transcript 1	0.038	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.038	Mouse
Snai1	snail homolog 1 (Drosophila)	0.038
Aim2	absent in melanoma 2	0.036
Pdx1	pancreatic and duodenal homeobox 1	0.036
Hoxc4	homeobox C4	0.036
T	brachyury	0.035
Hmx3	H6 homeobox 3	0.035
Srrm4	serine/arginine repetitive matrix 4	0.034
Fgf3	fibroblast growth factor 3	0.033
Msi1	Musashi homolog 1(Drosophila)	0.031
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.031
Shox2	short stature homeobox 2	0.030
Fgf9	fibroblast growth factor 9	0.030
Mecom	MDS1 and EVI1 complex locus	0.030
Fbn2	fibrillin 2	0.030
Fgf15	fibroblast growth factor 15	0.029
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.029
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.029
Zic1	zinc finger protein of the cerebellum 1	0.029
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.029
Esrrb	estrogen related receptor, beta	0.029
Hoxc9	homeobox C9	0.029	Mouse
Dlx6	distal-less homeobox 6	0.029
Tbx1	T-box 1	0.028
Col22a1	collagen, type XXII, alpha 1	0.028
Onecut2	one cut domain, family member 2	0.027
Arx	aristaless related homeobox	0.027
Gpr50	G-protein-coupled receptor 50	0.027
Socs1	suppressor of cytokine signaling 1	0.027
Hoxa7	homeobox A7	0.026
Zic2	zinc finger protein of the cerebellum 2	0.026
Hoxd10	homeobox D10	0.026
Atoh7	atonal homolog 7 (Drosophila)	0.025	Mouse
Nog	noggin	0.025
Gata1	GATA binding protein 1	0.025
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.024
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.024
Osr1	odd-skipped related 1 (Drosophila)	0.024
Vsx2	visual system homeobox 2	0.024
Tgfb2	transforming growth factor, beta 2	0.023
Odz2	odd Oz/ten-m homolog 2 (Drosophila)	0.023
Syt2	synaptotagmin II	0.022
Fgf18	fibroblast growth factor 18	0.022
Kiss1	KiSS-1 metastasis-suppressor	0.022
Fgf17	fibroblast growth factor 17	0.022
Neurog3	neurogenin 3	0.022	Zebrafish Mouse
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.022
Mnx1	motor neuron and pancreas homeobox 1	0.022
Nefm	neurofilament, medium polypeptide	0.022	Mouse
Robo3	roundabout homolog 3 (Drosophila)	0.022
Hoxd12	homeobox D12	0.021
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.021
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.021
Tbx15	T-box 15	0.020
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.020
Casq1	calsequestrin 1	0.020
Hoxa2	homeobox A2	0.019
Atp6v0b	ATPase, H+ transporting, lysosomal V0 subunit B	0.018
Hoxb13	homeobox B13	0.018
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.018
Magel2	melanoma antigen, family L, 2	0.018
Celf4	CUGBP, Elav-like family member 4	0.018
Hmga2	high mobility group AT-hook 2	0.017
Olig2	oligodendrocyte transcription factor 2	0.017
Hoxa5	homeobox A5	0.017
Ppt1	palmitoyl-protein thioesterase 1	0.017
Hoxb8	homeobox B8	0.017
Dlx5	distal-less homeobox 5	0.017
Foxh1	forkhead box H1	0.016
Sox9	SRY-box containing gene 9	0.016
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.016
Efna5	ephrin A5	0.016
Dlk1	delta-like 1 homolog (Drosophila)	0.016
Rtn4r	reticulon 4 receptor	0.015
Ret	ret proto-oncogene	0.015
Igfbpl1	insulin-like growth factor binding protein-like 1	0.015
S1pr2	sphingosine-1-phosphate receptor 2	0.015
Fgf6	fibroblast growth factor 6	0.015
Foxd1	forkhead box D1	0.015
Ptch2	patched homolog 2	0.015
Fgf4	fibroblast growth factor 4	0.015
Wnt6	wingless-related MMTV integration site 6	0.015
Evx1	even skipped homeotic gene 1 homolog	0.015
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.015
Sall4	sal-like 4 (Drosophila)	0.015
Hoxd8	homeobox D8	0.015
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.014
Hoxd4	homeobox D4	0.014
Tbr1	T-box brain gene 1	0.014
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.014
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.014
Nefl	neurofilament, light polypeptide	0.013	Mouse
Pax1	paired box gene 1	0.013
Tnf	tumor necrosis factor	0.013
Zic3	zinc finger protein of the cerebellum 3	0.013
Tcfap2b	transcription factor AP-2 beta	0.013
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.013
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.013
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.013
Ncs1	neuronal calcium sensor 1	0.013
Isl2	insulin related protein 2 (islet 2)	0.013	Mouse
Hoxb4	homeobox B4	0.013
Adcyap1	adenylate cyclase activating polypeptide 1	0.013
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.013
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.013
Tlx2	T-cell leukemia, homeobox 2	0.013
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.013
Myd88	myeloid differentiation primary response gene 88	0.013
Mark1	MAP/microtubule affinity-regulating kinase 1	0.013
Dll1	delta-like 1 (Drosophila)	0.013
Foxp2	forkhead box P2	0.013
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.012	Mouse
Nkain1	Na+/K+ transporting ATPase interacting 1	0.012
Hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.012
Meis2	Meis homeobox 2	0.012
Tcf15	transcription factor 15	0.012	Mouse
En2	engrailed 2	0.012
Ddr2	discoidin domain receptor family, member 2	0.012
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.012
Gal	galanin	0.012
Ank1	ankyrin 1, erythroid	0.012
Meox1	mesenchyme homeobox 1	0.012
Wnt3	wingless-related MMTV integration site 3	0.012
Auts2	autism susceptibility candidate 2	0.012
Lhx6	LIM homeobox protein 6	0.012	Mouse
Il6st	interleukin 6 signal transducer	0.012
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.012
Gata3	GATA binding protein 3	0.012
Trim62	tripartite motif-containing 62	0.012
Vangl2	vang-like 2 (van gogh, Drosophila)	0.011
Lmx1b	LIM homeobox transcription factor 1 beta	0.011	Mouse
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.011
Pax9	paired box gene 9	0.011
Chrna3	cholinergic receptor, nicotinic, alpha polypeptide 3	0.011
Lhx4	LIM homeobox protein 4	0.011	Mouse
Zic4	zinc finger protein of the cerebellum 4	0.011
Hoxc10	homeobox C10	0.011	Mouse
Foxd3	forkhead box D3	0.011
Lmo2	LIM domain only 2	0.011
Twist1	twist homolog 1 (Drosophila)	0.011	Mouse
Hoxb6	homeobox B6	0.011
Hmx1	H6 homeobox 1	0.011
Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	0.011
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.011
Grem1	gremlin 1	0.011
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.011
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.011
Ssbp3	single-stranded DNA binding protein 3	0.011
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.010
Eya4	eyes absent 4 homolog (Drosophila)	0.010	Zebrafish
Sox10	SRY-box containing gene 10	0.010
Zfp362	zinc finger protein 362	0.010
Edar	ectodysplasin-A receptor	0.010
Pax7	paired box gene 7	0.010
Fgfr1	fibroblast growth factor receptor 1	0.010
Mmp24	matrix metallopeptidase 24	0.010