IMP

Process View

Mus musculus

8 genes annotated in mouse

gamma aminobutyric acid signaling pathway

The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gamma aminobutyric acid signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "gamma aminobutyric acid signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	1.000
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	1.000	Mouse
Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2	0.998	Mouse
Grid1	glutamate receptor, ionotropic, delta 1	0.995
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.995
Syn2	synapsin II	0.974
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.912
Thrb	thyroid hormone receptor beta	0.889
Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	0.873
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.842	Mouse
Gabra5	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5	0.807	Mouse
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.742
Nrg1	neuregulin 1	0.721
Gad2	glutamic acid decarboxylase 2	0.674
Grm1	glutamate receptor, metabotropic 1	0.671
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.609	Mouse
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	0.525	Mouse
Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1	0.519
Vti1a	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)	0.516
Slc12a5	solute carrier family 12, member 5	0.483
Dst	dystonin	0.447
Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	0.409	Mouse
Dynlt1b	dynein light chain Tctex-type 1D	0.403
Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	0.344	Mouse Rat
Grm8	glutamate receptor, metabotropic 8	0.313
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.274
Ntf3	neurotrophin 3	0.243	Mouse
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.241
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.215
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.211
Flt1	FMS-like tyrosine kinase 1	0.203
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.193
Bsn	bassoon	0.168
En2	engrailed 2	0.158
Pgr	progesterone receptor	0.151
Grid2	glutamate receptor, ionotropic, delta 2	0.141
Cntn4	contactin 4	0.128
Nxph1	neurexophilin 1	0.115
Ret	ret proto-oncogene	0.114
Gabrb1	gamma-aminobutyric acid (GABA) A receptor, subunit beta 1	0.112	Mouse
Npy1r	neuropeptide Y receptor Y1	0.110
Shc3	src homology 2 domain-containing transforming protein C3	0.106
Prkcc	protein kinase C, gamma	0.106
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.105
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.103
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.099
Cnr1	cannabinoid receptor 1 (brain)	0.098
Npy2r	neuropeptide Y receptor Y2	0.095
Ryr3	ryanodine receptor 3	0.094
Plcb1	phospholipase C, beta 1	0.093	Mouse
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.093
Syt1	synaptotagmin I	0.088
Bdnf	brain derived neurotrophic factor	0.080
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.079	Mouse
Cdh9	cadherin 9	0.078
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.071
Rit2	Ras-like without CAAX 2	0.069
Neurod1	neurogenic differentiation 1	0.069
Rho	rhodopsin	0.065
Neto1	neuropilin (NRP) and tolloid (TLL)-like 1	0.065
Ryr1	ryanodine receptor 1, skeletal muscle	0.065
Tbx10	T-box 10	0.063
Slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	0.061
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.060
Zfpm2	zinc finger protein, multitype 2	0.059
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.057
Cacnb4	calcium channel, voltage-dependent, beta 4 subunit	0.057
Ntf5	neurotrophin 5	0.055	Mouse
Drd2	dopamine receptor D2	0.055
Trhr	thyrotropin releasing hormone receptor	0.054
Phox2a	paired-like homeobox 2a	0.052
Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3	0.050	Mouse
Dlg4	discs, large homolog 4 (Drosophila)	0.048
Kcnk3	potassium channel, subfamily K, member 3	0.047
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.045
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.044
Braf	Braf transforming gene	0.043
Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	0.042
Calb1	calbindin 1	0.042
Neurod6	neurogenic differentiation 6	0.041
Tac2	tachykinin 2	0.040
Vti1b	vesicle transport through interaction with t-SNAREs 1B homolog	0.040
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	0.038	Mouse
Nrg3	neuregulin 3	0.037
Mid1	midline 1	0.037
Plp1	proteolipid protein (myelin) 1	0.037
Homer1	homer homolog 1 (Drosophila)	0.037
Ids	iduronate 2-sulfatase	0.037
Gal	galanin	0.035
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.034	Mouse
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.033
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.033
Plcb3	phospholipase C, beta 3	0.032	Mouse
Sstr4	somatostatin receptor 4	0.031
Rasgrp1	RAS guanyl releasing protein 1	0.030
Cplx3	complexin 3	0.030
Serpinb11	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11	0.029
Hcrt	hypocretin	0.029
Bin1	bridging integrator 1	0.029
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.027
Gpr12	G-protein coupled receptor 12	0.027
Oprk1	opioid receptor, kappa 1	0.027
Nxph2	neurexophilin 2	0.026
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.026
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.026
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.026
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.026
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.025
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.025
Epha5	Eph receptor A5	0.025
Rgs6	regulator of G-protein signaling 6	0.024
Epha4	Eph receptor A4	0.024
Tacr3	tachykinin receptor 3	0.024
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.024
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.023
Ryr2	ryanodine receptor 2, cardiac	0.023
Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.023	Mouse
Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta	0.023	Mouse
Blnk	B-cell linker	0.022
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.022
Klf12	Kruppel-like factor 12	0.022
Bcl7a	B-cell CLL/lymphoma 7A	0.021
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.021
Oprl1	opioid receptor-like 1	0.021
Efna1	ephrin A1	0.021
Vstm2a	V-set and transmembrane domain containing 2A	0.021
Mmp16	matrix metallopeptidase 16	0.020
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.020
Cd22	CD22 antigen	0.020
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.020
Npy5r	neuropeptide Y receptor Y5	0.020
Pcdh10	protocadherin 10	0.020
Npy6r	neuropeptide Y receptor Y6	0.020
Ephb3	Eph receptor B3	0.020
Ppfia4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.020
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.019
Tacr1	tachykinin receptor 1	0.019
Dync1i1	dynein cytoplasmic 1 intermediate chain 1	0.019
Cdh8	cadherin 8	0.019
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.018
Dlgap4	discs, large homolog-associated protein 4 (Drosophila)	0.018
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.018
Chrd	chordin	0.017
Hivep3	human immunodeficiency virus type I enhancer binding protein 3	0.017
Sh3gl2	SH3-domain GRB2-like 2	0.017
Cplx4	complexin 4	0.017
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.017
Galr1	galanin receptor 1	0.017
Ctsr	cathepsin R	0.017
Gsbs	G substrate	0.017
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.017
Camk4	calcium/calmodulin-dependent protein kinase IV	0.017
Slc26a4	solute carrier family 26, member 4	0.017
Gjd2	gap junction protein, delta 2	0.016
Nap1l2	nucleosome assembly protein 1-like 2	0.016
Pth2r	parathyroid hormone 2 receptor	0.016
Dlg2	discs, large homolog 2 (Drosophila)	0.016
Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	0.016
Il1f8	interleukin 1 family, member 8	0.015
Ikbkap	inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein	0.015
Cadps	Ca2+-dependent secretion activator	0.015
Plag1	pleiomorphic adenoma gene 1	0.015
Slitrk4	SLIT and NTRK-like family, member 4	0.015
Kif5a	kinesin family member 5A	0.015
Mgat4c	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)	0.014
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.014
Prkch	protein kinase C, eta	0.014
Slitrk6	SLIT and NTRK-like family, member 6	0.014
Npas2	neuronal PAS domain protein 2	0.014
Agap2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.013
Cdh10	cadherin 10	0.013
Plcb2	phospholipase C, beta 2	0.013	Mouse
Efnb1	ephrin B1	0.013
Rorb	RAR-related orphan receptor beta	0.013
Cntn1	contactin 1	0.013
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.013
Ncam2	neural cell adhesion molecule 2	0.013
Kifc2	kinesin family member C2	0.012
Cntnap2	contactin associated protein-like 2	0.012
Odz1	odd Oz/ten-m homolog 1 (Drosophila)	0.011
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.011
Cga	glycoprotein hormones, alpha subunit	0.011
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.011
Tub	tubby candidate gene	0.011
Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	0.011
Duoxa2	dual oxidase maturation factor 2	0.011
Rfpl4	ret finger protein-like 4	0.011
Insl5	insulin-like 5	0.011
Folh1	folate hydrolase	0.011
Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.011
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.011
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.011
4931408A02Rik	RIKEN cDNA 4931408A02 gene	0.011
Gad1	glutamic acid decarboxylase 1	0.011
Eml6	echinoderm microtubule associated protein like 6	0.010
Aff2	AF4/FMR2 family, member 2	0.010
Tll1	tolloid-like	0.010
Il16	interleukin 16	0.010
2310057N15Rik	RIKEN cDNA 2310057N15 gene	0.010
Astn2	astrotactin 2	0.010
Tbr1	T-box brain gene 1	0.010
Tac1	tachykinin 1	0.010
Adarb2	adenosine deaminase, RNA-specific, B2	0.010
Nrsn1	neurensin 1	0.010
Inpp5d	inositol polyphosphate-5-phosphatase D	0.010
Gabre	gamma-aminobutyric acid (GABA) A receptor, subunit epsilon	0.010	Mouse Rat