IMP

Process View

Mus musculus

19 genes annotated in mouse

Multi-species View

branch elongation of an epithelium

GO:0060602

The growth process in which a branch increases in length from its base to its tip.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "branch elongation of an epithelium"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "branch elongation of an epithelium" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.999
Fgfr2	fibroblast growth factor receptor 2	0.957
Gli3	GLI-Kruppel family member GLI3	0.942
Fgf10	fibroblast growth factor 10	0.921
Pax3	paired box gene 3	0.921
Pax2	paired box gene 2	0.917
Fgf8	fibroblast growth factor 8	0.829
Foxc1	forkhead box C1	0.758
Fgfr3	fibroblast growth factor receptor 3	0.743	Mouse
Ret	ret proto-oncogene	0.630
Fgf9	fibroblast growth factor 9	0.585	Mouse
Pax8	paired box gene 8	0.523
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.492
Amhr2	anti-Mullerian hormone type 2 receptor	0.471
Bmp4	bone morphogenetic protein 4	0.424
Meox2	mesenchyme homeobox 2	0.421
Alx4	aristaless-like homeobox 4	0.357
Hoxd13	homeobox D13	0.313
Pou3f3	POU domain, class 3, transcription factor 3	0.310
Tgfa	transforming growth factor alpha	0.288
Lhx1	LIM homeobox protein 1	0.280
Gli2	GLI-Kruppel family member GLI2	0.275
Esrrb	estrogen related receptor, beta	0.274	Mouse
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.254
Nodal	nodal	0.249
Hoxa13	homeobox A13	0.242	Mouse
Ar	androgen receptor	0.228
Sox9	SRY-box containing gene 9	0.208
Hoxd11	homeobox D11	0.200
Rarb	retinoic acid receptor, beta	0.194
Tbx2	T-box 2	0.192
Prrx2	paired related homeobox 2	0.191
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.180
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.177
Hoxa11	homeobox A11	0.173
Spry2	sprouty homolog 2 (Drosophila)	0.166
Twist2	twist homolog 2 (Drosophila)	0.164
Pax6	paired box gene 6	0.151
Kl	klotho	0.142
Nog	noggin	0.123
Tbx3	T-box 3	0.119
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.119
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.115	Mouse
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.115
Spry4	sprouty homolog 4 (Drosophila)	0.114	Mouse
Wnt5a	wingless-related MMTV integration site 5A	0.113
Foxf1a	forkhead box F1a	0.111
Gdnf	glial cell line derived neurotrophic factor	0.107
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.106
Foxf2	forkhead box F2	0.106
Ptch1	patched homolog 1	0.104
Pitx2	paired-like homeodomain transcription factor 2	0.094
Wnt3a	wingless-related MMTV integration site 3A	0.088	Mouse
Tcf21	transcription factor 21	0.086
Foxc2	forkhead box C2	0.086
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.085
Eya1	eyes absent 1 homolog (Drosophila)	0.083
Hoxa10	homeobox A10	0.081
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.081
Fzd8	frizzled homolog 8 (Drosophila)	0.079
Pax7	paired box gene 7	0.078
Prrx1	paired related homeobox 1	0.078
Fst	follistatin	0.074
Tcfap2c	transcription factor AP-2, gamma	0.074
Pbx1	pre B-cell leukemia transcription factor 1	0.072
Pthlh	parathyroid hormone-like peptide	0.071
Otx2	orthodenticle homolog 2 (Drosophila)	0.070
Lmx1a	LIM homeobox transcription factor 1 alpha	0.069
Gdf11	growth differentiation factor 11	0.068	Mouse
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.067
Wnt4	wingless-related MMTV integration site 4	0.067	Mouse
Fgf3	fibroblast growth factor 3	0.065	Mouse
Ntf3	neurotrophin 3	0.065
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.063
Fgf18	fibroblast growth factor 18	0.062
Emx1	empty spiracles homolog 1 (Drosophila)	0.060
Kiss1	KiSS-1 metastasis-suppressor	0.060
Npr3	natriuretic peptide receptor 3	0.059
Gdf1	growth differentiation factor 1	0.057	Mouse
Nos3	nitric oxide synthase 3, endothelial cell	0.057
Pgr	progesterone receptor	0.057
Nkx2-1	NK2 homeobox 1	0.056
Hand1	heart and neural crest derivatives expressed transcript 1	0.056
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.055
Tbx15	T-box 15	0.054
Otx1	orthodenticle homolog 1 (Drosophila)	0.054
Gja3	gap junction protein, alpha 3	0.054
Emx2	empty spiracles homolog 2 (Drosophila)	0.053
Rarg	retinoic acid receptor, gamma	0.052
Hoxd3	homeobox D3	0.052
Hoxa1	homeobox A1	0.051
Acan	aggrecan	0.050
Lhx3	LIM homeobox protein 3	0.048
Bmp7	bone morphogenetic protein 7	0.047
Hand2	heart and neural crest derivatives expressed transcript 2	0.046
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.045
Hoxa5	homeobox A5	0.041
Lrp2	low density lipoprotein receptor-related protein 2	0.041
Apc	adenomatosis polyposis coli	0.041
Foxh1	forkhead box H1	0.041
Epha1	Eph receptor A1	0.040
Pax1	paired box gene 1	0.039
Gli1	GLI-Kruppel family member GLI1	0.039
Sim2	single-minded homolog 2 (Drosophila)	0.039
Btbd17	BTB (POZ) domain containing 17	0.038
Barx2	BarH-like homeobox 2	0.038
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.036
Esr1	estrogen receptor 1 (alpha)	0.036
Fgf4	fibroblast growth factor 4	0.036	Mouse
Drd2	dopamine receptor D2	0.035
Bmper	BMP-binding endothelial regulator	0.035
Fshr	follicle stimulating hormone receptor	0.034
Slurp1	secreted Ly6/Plaur domain containing 1	0.034
Foxd2	forkhead box D2	0.034
Atoh7	atonal homolog 7 (Drosophila)	0.033
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.033
Fgf5	fibroblast growth factor 5	0.032	Mouse
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.032
Bdnf	brain derived neurotrophic factor	0.032
Crhr2	corticotropin releasing hormone receptor 2	0.032
Col2a1	collagen, type II, alpha 1	0.032
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.031
Zeb1	zinc finger E-box binding homeobox 1	0.030
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.030
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.030
Fgfbp1	fibroblast growth factor binding protein 1	0.029
T	brachyury	0.029
Npas1	neuronal PAS domain protein 1	0.029
Gata3	GATA binding protein 3	0.029
Fgf17	fibroblast growth factor 17	0.029
Bmp5	bone morphogenetic protein 5	0.029
Lepr	leptin receptor	0.028
Vangl2	vang-like 2 (van gogh, Drosophila)	0.028
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.028
Sox2	SRY-box containing gene 2	0.028	Mouse
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.027
Lep	leptin	0.027
Bcl2	B-cell leukemia/lymphoma 2	0.027
Matn3	matrilin 3	0.027
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.027
Msx2	homeobox, msh-like 2	0.027
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.027
Pou5f1	POU domain, class 5, transcription factor 1	0.026
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.026
Clcnka	chloride channel Ka	0.026
Pitx1	paired-like homeodomain transcription factor 1	0.026
Foxa2	forkhead box A2	0.026
En1	engrailed 1	0.026
Dhh	desert hedgehog	0.026	Mouse
Vdr	vitamin D receptor	0.025
Fgf23	fibroblast growth factor 23	0.025
Hoxb13	homeobox B13	0.025	Mouse
Sox7	SRY-box containing gene 7	0.025	Mouse
Foxi3	forkhead box I3	0.024
Gdf5	growth differentiation factor 5	0.024
Hoxa9	homeobox A9	0.024
Inhbb	inhibin beta-B	0.024
Chrd	chordin	0.024
Cdh13	cadherin 13	0.024
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.024
Hoxd9	homeobox D9	0.024
Pou3f4	POU domain, class 3, transcription factor 4	0.023
Gbx2	gastrulation brain homeobox 2	0.023
Wfikkn1	WAP, FS, Ig, KU, and NTR-containing protein 1	0.023
Neurog3	neurogenin 3	0.023
Vstm2b	V-set and transmembrane domain containing 2B	0.023
Efna2	ephrin A2	0.023
Wnt2b	wingless related MMTV integration site 2b	0.023	Mouse
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.023
Irx3	Iroquois related homeobox 3 (Drosophila)	0.022
Hoxb4	homeobox B4	0.022
Sall4	sal-like 4 (Drosophila)	0.022
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.022
Hoxb3	homeobox B3	0.021
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.021
She	src homology 2 domain-containing transforming protein E	0.021
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.021
Cdx1	caudal type homeobox 1	0.020
Nos1	nitric oxide synthase 1, neuronal	0.020
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.020
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.020
Eda	ectodysplasin-A	0.020
Tpo	thyroid peroxidase	0.020
Smo	smoothened homolog (Drosophila)	0.019
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.019
Wnt7a	wingless-related MMTV integration site 7A	0.019	Mouse
Ghr	growth hormone receptor	0.019
BC021891	cDNA sequence BC021891	0.019
Tcf15	transcription factor 15	0.019
Hmx3	H6 homeobox 3	0.019
Hoxb9	homeobox B9	0.019
Barx1	BarH-like homeobox 1	0.019
Smad6	MAD homolog 6 (Drosophila)	0.018
Clic3	chloride intracellular channel 3	0.018
Ihh	Indian hedgehog	0.018	Mouse
Tcfap2a	transcription factor AP-2, alpha	0.018	Mouse
Hhip	Hedgehog-interacting protein	0.018
Foxb1	forkhead box B1	0.018
Cldn8	claudin 8	0.018
Wnt3	wingless-related MMTV integration site 3	0.018	Mouse
Wnt10b	wingless related MMTV integration site 10b	0.018	Mouse
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.018
Tdgf1	teratocarcinoma-derived growth factor 1	0.018
Gas1	growth arrest specific 1	0.017
Esr2	estrogen receptor 2 (beta)	0.017	Mouse
Ext1	exostoses (multiple) 1	0.017
Trp63	transformation related protein 63	0.017
Smad3	MAD homolog 3 (Drosophila)	0.017
Fhl3	four and a half LIM domains 3	0.017
Myog	myogenin	0.017
Csf3	colony stimulating factor 3 (granulocyte)	0.017
Pou3f1	POU domain, class 3, transcription factor 1	0.017
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.017
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.017
Snai1	snail homolog 1 (Drosophila)	0.017
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.017
Sox11	SRY-box containing gene 11	0.017	Mouse
Neurog1	neurogenin 1	0.017
Eya4	eyes absent 4 homolog (Drosophila)	0.017
Pkdcc	protein kinase domain containing, cytoplasmic	0.017
Fzd10	frizzled homolog 10 (Drosophila)	0.017
Myod1	myogenic differentiation 1	0.016
Hoxd8	homeobox D8	0.016
Inhba	inhibin beta-A	0.016
Foxe3	forkhead box E3	0.016
Onecut1	one cut domain, family member 1	0.016
Kiss1r	KISS1 receptor	0.016
Mmp24	matrix metallopeptidase 24	0.016
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.016
AI118078	expressed sequence AI118078	0.016
Nes	nestin	0.016
Socs5	suppressor of cytokine signaling 5	0.016
Zbtb16	zinc finger and BTB domain containing 16	0.016
Pitx3	paired-like homeodomain transcription factor 3	0.016
Pten	phosphatase and tensin homolog	0.016
Hoxa7	homeobox A7	0.016
Cdh16	cadherin 16	0.016
Krt13	keratin 13	0.016
Efs	embryonal Fyn-associated substrate	0.016
Npas3	neuronal PAS domain protein 3	0.015
Rara	retinoic acid receptor, alpha	0.015
Nhlh1	nescient helix loop helix 1	0.015
BC024139	cDNA sequence BC024139	0.015
Prlr	prolactin receptor	0.015
Nf1	neurofibromatosis 1	0.015
Foxd1	forkhead box D1	0.015
Adra1a	adrenergic receptor, alpha 1a	0.015
Meis2	Meis homeobox 2	0.015
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.014
Tbx10	T-box 10	0.014
Zfp771	zinc finger protein 771	0.014
Ikbkap	inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein	0.014
Adra2b	adrenergic receptor, alpha 2b	0.014
Hmx1	H6 homeobox 1	0.014
Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2	0.014
Zfp503	zinc finger protein 503	0.014
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.014
Cabp7	calcium binding protein 7	0.014
Kitl	kit ligand	0.014
Btc	betacellulin, epidermal growth factor family member	0.014
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.014
Hoxd4	homeobox D4	0.014
Zic2	zinc finger protein of the cerebellum 2	0.014
Pvrl1	poliovirus receptor-related 1	0.014
Zfp703	zinc finger protein 703	0.014
Magix	MAGI family member, X-linked	0.014
Mapk12	mitogen-activated protein kinase 12	0.014
Ptprb	protein tyrosine phosphatase, receptor type, B	0.014
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.014
Gata6	GATA binding protein 6	0.014
Tead4	TEA domain family member 4	0.014
Mgat3	mannoside acetylglucosaminyltransferase 3	0.013
Agtr2	angiotensin II receptor, type 2	0.013
Ttc16	tetratricopeptide repeat domain 16	0.013
Vipr1	vasoactive intestinal peptide receptor 1	0.013
Rxrg	retinoid X receptor gamma	0.013
Wnt9a	wingless-type MMTV integration site 9A	0.013	Mouse
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.013
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.013
Hic1	hypermethylated in cancer 1	0.013
Edil3	EGF-like repeats and discoidin I-like domains 3	0.013
Meox1	mesenchyme homeobox 1	0.013
Edar	ectodysplasin-A receptor	0.013
C77370	expressed sequence C77370	0.013
Edn3	endothelin 3	0.013
Fzd4	frizzled homolog 4 (Drosophila)	0.013
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.013
Dmrt1	doublesex and mab-3 related transcription factor 1	0.013
Hoxd1	homeobox D1	0.013
Cntn4	contactin 4	0.013
Bmp15	bone morphogenetic protein 15	0.013
Porcn	porcupine homolog (Drosophila)	0.013
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.013
Socs1	suppressor of cytokine signaling 1	0.013
Fam164c	family with sequence similarity 164, member C	0.013
Sftpc	surfactant associated protein C	0.012
Gata5	GATA binding protein 5	0.012
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.012
Hoxc9	homeobox C9	0.012
Lama3	laminin, alpha 3	0.012
Tead3	TEA domain family member 3	0.012
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.012	Mouse
Bhlhe23	basic helix-loop-helix family, member e23	0.012
Sh3rf1	SH3 domain containing ring finger 1	0.012
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.012
Fzd7	frizzled homolog 7 (Drosophila)	0.012
Slc25a48	solute carrier family 25, member 48	0.012
Nppc	natriuretic peptide type C	0.012
Lhb	luteinizing hormone beta	0.012
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.012
Lhx5	LIM homeobox protein 5	0.012
Sall1	sal-like 1 (Drosophila)	0.012
Hapln1	hyaluronan and proteoglycan link protein 1	0.012
Fgf15	fibroblast growth factor 15	0.012
Nfia	nuclear factor I/A	0.012
Rxra	retinoid X receptor alpha	0.012
Hoxb6	homeobox B6	0.012
Kcnk3	potassium channel, subfamily K, member 3	0.012
Fzd1	frizzled homolog 1 (Drosophila)	0.012
Cacng6	calcium channel, voltage-dependent, gamma subunit 6	0.012
Dlx4	distal-less homeobox 4	0.012
H1foo	H1 histone family, member O, oocyte-specific	0.012
Epb4.1l4b	erythrocyte protein band 4.1-like 4b	0.011
Nrtn	neurturin	0.011
Hrc	histidine rich calcium binding protein	0.011
Lrp4	low density lipoprotein receptor-related protein 4	0.011
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
Efna4	ephrin A4	0.011
Ctf1	cardiotrophin 1	0.011
Des	desmin	0.011
Emid1	EMI domain containing 1	0.011
Amh	anti-Mullerian hormone	0.011
Meis1	Meis homeobox 1	0.011
Adrb1	adrenergic receptor, beta 1	0.011
Zic3	zinc finger protein of the cerebellum 3	0.011
Foxb2	forkhead box B2	0.011
Krt16	keratin 16	0.011
Tbx1	T-box 1	0.011
Npas2	neuronal PAS domain protein 2	0.011
Ano1	anoctamin 1, calcium activated chloride channel	0.011
Cldn5	claudin 5	0.011
Col22a1	collagen, type XXII, alpha 1	0.011
Oprd1	opioid receptor, delta 1	0.011
BC057022	cDNA sequence BC057022	0.011
Rcvrn	recoverin	0.011
Hoxa4	homeobox A4	0.011
Nkx6-1	NK6 homeobox 1	0.011
Siah2	seven in absentia 2	0.011
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.011
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.011
Alox12b	arachidonate 12-lipoxygenase, 12R type	0.010
Myl3	myosin, light polypeptide 3	0.010
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.010
Krt72-ps	keratin 72, pseudogene	0.010
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.010
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.010
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.010
Fgf21	fibroblast growth factor 21	0.010
Bdkrb2	bradykinin receptor, beta 2	0.010
Avpr2	arginine vasopressin receptor 2	0.010
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.010
Crlf1	cytokine receptor-like factor 1	0.010
Nkx6-3	NK6 homeobox 3	0.010
Nobox	NOBOX oogenesis homeobox	0.010
Pcdh12	protocadherin 12	0.010
Cdh6	cadherin 6	0.010
Fosl2	fos-like antigen 2	0.010
Glra1	glycine receptor, alpha 1 subunit	0.010