IMP

Process View

Rattus norvegicus

1 genes annotated in rat

regulation of natural killer cell mediated immune response to tumor cell

Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of natural killer cell mediated immune response to tumor cell"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of natural killer cell mediated immune response to tumor cell" (in gray)

Name	Description	Probability	Func Analog Organism
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.958
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.891	Rat
Il7r	interleukin 7 receptor	0.842
Ccr2	chemokine (C-C motif) receptor 2	0.750
Tlr7	toll-like receptor 7	0.698
Klrc2	killer cell lectin-like receptor subfamily C, member 2	0.508	Rat
Nkg7	natural killer cell group 7 sequence	0.483
Gzmk	granzyme K	0.469
Sell	selectin L	0.444
Ccl2	chemokine (C-C motif) ligand 2	0.386
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.344	Rat
Xcl1	chemokine (C motif) ligand 1	0.337
Gzmm	granzyme M (lymphocyte met-ase 1)	0.214
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.210
Gzmb	granzyme B	0.205
Cd8a	CD8a molecule	0.195
Junb	jun B proto-oncogene	0.163
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.157
Vom1r93	vomeronasal 1 receptor 93	0.157
Mmp12	matrix metallopeptidase 12	0.151
Igsf6	immunoglobulin superfamily, member 6	0.148
Prf1	perforin 1 (pore forming protein)	0.136
Mcpt8	mast cell protease 8	0.129
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.129
Il1rl1	interleukin 1 receptor-like 1	0.126
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.110
Cd2	Cd2 molecule	0.110
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.108
Serpinb3a	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A	0.105
Cd72	Cd72 molecule	0.102
Clec12a	C-type lectin domain family 12, member A	0.095
Rgs1	regulator of G-protein signaling 1	0.095
Clec4f	C-type lectin domain family 4, member f	0.093
Ccl4	chemokine (C-C motif) ligand 4	0.092
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.090
Tnfrsf12a	tumor necrosis factor receptor superfamily, member 12a	0.090
Il6	interleukin 6	0.089
Ccl5	chemokine (C-C motif) ligand 5	0.083
Slc9a4	solute carrier family 9 (sodium/hydrogen exchanger), member 4	0.074
Clec9a	C-type lectin domain family 9, member a	0.073	Rat
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.072	Rat
Zap70	zeta-chain (TCR) associated protein kinase	0.072
Ifng	interferon gamma	0.070
Cxcl10	chemokine (C-X-C motif) ligand 10	0.069
Faslg	Fas ligand (TNF superfamily, member 6)	0.066
Igfl3	IGF-like family member 3	0.065
Fcer1a	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	0.061
Ccr5	chemokine (C-C motif) receptor 5	0.060
Tfec	transcription factor EC	0.056
Klra22	killer cell lectin-like receptor subfamily A, member 22	0.055	Rat
LOC300024	similar to Ly6-B antigen gene	0.054
Gpx2	glutathione peroxidase 2	0.053
Unc5cl	unc-5 homolog C (C. elegans)-like	0.052
Tnni3k	TNNI3 interacting kinase	0.051
Gucy2g	guanylate cyclase 2G	0.051
Oas1b	2-5 oligoadenylate synthetase 1B	0.050
Atf3	activating transcription factor 3	0.050
Fcgr1a	Fc fragment of IgG, high affinity Ia, receptor (CD64)	0.050
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.049
Vom1r102	vomeronasal 1 receptor 102	0.048
Fam65b	family with sequence similarity 65, member B	0.048
Prl2a1	Prolactin family 2, subfamily a, member 1	0.046
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.046	Rat
Reg3g	regenerating islet-derived 3 gamma	0.045
Myc	myelocytomatosis oncogene	0.044
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.041
Mos	Moloney sarcoma oncogene	0.040
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.040
Havcr1	hepatitis A virus cellular receptor 1	0.038
Ccl9	chemokine (C-C motif) ligand 9	0.037
Mcpt3	mast cell peptidase 3	0.037
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.036
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.035
Oasl	2'-5'-oligoadenylate synthetase-like	0.034
Sh2d2a	SH2 domain protein 2A	0.034
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.034
Sit1	signaling threshold regulating transmembrane adaptor 1	0.034
Ccl3	chemokine (C-C motif) ligand 3	0.034
Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.033
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.033
S100vp	S100 calcium-binding protein, ventral prostate	0.033
Mcpt4	mast cell protease 4	0.033
Pla1a	phospholipase A1 member A	0.033
Cd3g	CD3 molecule, gamma	0.032
Ctsj	cathepsin J	0.032
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.030
Lrrc8c	leucine rich repeat containing 8 family, member C	0.029
Serpinb3	serine protease inhibitor B3	0.028
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.028
Prl2b1	Prolactin family 2, subfamily b, member 1	0.028
Slamf9	SLAM family member 9	0.028
Pou1f1	POU class 1 homeobox 1	0.028
Phex	phosphate regulating endopeptidase homolog, X-linked	0.028
Gzma	granzyme A	0.027
Scin	scinderin	0.027
Spink1	serine peptidase inhibitor, Kazal type 1	0.027
Ubd	ubiquitin D	0.027
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.025
Cd244	Cd244 molecule, natural killer cell receptor 2B4	0.024
Slfn3	schlafen 3	0.024
Il18r1	interleukin 18 receptor 1	0.023
Cd38	CD38 molecule	0.023
Sdc1	syndecan 1	0.023
Gfra3	GDNF family receptor alpha 3	0.022
Olr1283	olfactory receptor 1283	0.022
Fas	Fas (TNF receptor superfamily, member 6)	0.022
Gpr114	G protein-coupled receptor 114	0.021
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.021
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.021
Ccl19	chemokine (C-C motif) ligand 19	0.021
Zcwpw1	zinc finger, CW-type with PWWP domain 1	0.020
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.020
LOC494538	ABP beta	0.020
Stx11	syntaxin 11	0.020
Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)	0.019
MGC105649	hypothetical LOC302884	0.019
Spef2	sperm flagellar 2	0.019
Cxcl11	chemokine (C-X-C motif) ligand 11	0.019
Slc22a25	solute carrier family 22, member 25	0.019
Kcnv1	potassium channel, subfamily V, member 1	0.019
Ifrd1	interferon-related developmental regulator 1	0.018
Fut9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	0.018
RT1-A3	RT1 class I, locus A3	0.018
Skap1	src kinase associated phosphoprotein 1	0.018
Ncr3	natural cytotoxicity triggering receptor 3	0.018
Spn	sialophorin	0.018
Errfi1	ERBB receptor feedback inhibitor 1	0.018
Gpr64	G protein-coupled receptor 64	0.017
Il2rb	interleukin 2 receptor, beta	0.017
Txnrd1	thioredoxin reductase 1	0.017
Oprm1	opioid receptor, mu 1	0.017
Si	sucrase-isomaltase (alpha-glucosidase)	0.016
Crisp1	cysteine-rich secretory protein 1	0.016
Slc12a1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1	0.016
Fcrla	Fc receptor-like A	0.016
Ldhc	lactate dehydrogenase C	0.016
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.016
LOC100362325	rCG28200-like	0.016
Gstm3	glutathione S-transferase mu 3	0.015
Tmem182	transmembrane protein 182	0.015
Tas2r105	taste receptor, type 2, member 105	0.015
Maml2	mastermind like 2 (Drosophila)	0.015
Olr1226	olfactory receptor 1226	0.015
Tchh	trichohyalin	0.015
Sh2d1a	SH2 domain protein 1A	0.015
LOC24906	RoBo-1	0.015
Ctsm	cathepsin M	0.015
LOC100361765	homeobox B2	0.015
Tas2r114	taste receptor, type 2, member 114	0.014
Hnmt	histamine N-methyltransferase	0.014
Gimap4	GTPase, IMAP family member 4	0.014
Art2	ADP-ribosyltransferase 2	0.014
Klre1	killer cell lectin-like receptor, family E, member 1	0.014
Tmigd1	transmembrane and immunoglobulin domain containing 1	0.014
Plaur	plasminogen activator, urokinase receptor	0.014
Tdh	L-threonine dehydrogenase	0.014
Panx3	pannexin 3	0.014
Cd22	CD22 molecule	0.014
Hbegf	heparin-binding EGF-like growth factor	0.013
Cyp7b1	cytochrome P450, family 7, subfamily b, polypeptide 1	0.013
Irf2	interferon regulatory factor 2	0.013
LOC100361053	mCG1039741-like	0.013
Krtap13-2	keratin associated protein 13-2	0.013
Zfp37	zinc finger protein 37	0.013
Stap1	signal transducing adaptor family member 1	0.013
Atp6v1g3	ATPase, H+ transporting, lysosomal V1 subunit G3	0.013
Srxn1	sulfiredoxin 1 homolog (S. cerevisiae)	0.013
Dpp4	dipeptidylpeptidase 4	0.013
Duoxa1	dual oxidase maturation factor 1	0.013
Ambn	ameloblastin	0.013
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.013
Prl8a2	prolactin family 8, subfamily a, member 2	0.013
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.013
Cst7	cystatin F (leukocystatin)	0.012
Cst5	cystatin D	0.012
LOC680367	similar to Urinary protein 3 precursor (RUP-3)	0.012
Pak1ip1	PAK1 interacting protein 1	0.012
Ly49si1	immunoreceptor Ly49si1	0.012	Rat
Card6	caspase recruitment domain family, member 6	0.012
Runx1	runt-related transcription factor 1	0.012
Col4a3	collagen, type IV, alpha 3	0.012
Ier3	immediate early response 3	0.012
Testin	testin gene	0.012
Pik3cd	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.012
RT1-Ha	RT1 class II, locus Ha	0.012
Cdkn1a	cyclin-dependent kinase inhibitor 1A	0.012
Myct1	myc target 1	0.012
RGD1562844	similar to serine (or cysteine) proteinase inhibitor, clade B, member 9	0.012
Csn1s1	casein alpha s1	0.011
Il1rn	interleukin 1 receptor antagonist	0.011
Stfa2l3	stefin A2-like 3	0.011
Vcsa2	variable coding sequence A2	0.011
Olr59	olfactory receptor 59	0.011
Ugt1a3	UDP glycosyltransferase 1 family, polypeptide A3	0.011
LOC685834	similar to zinc finger protein 740	0.011
Apcs	amyloid P component, serum	0.011
Ldb3	LIM domain binding 3	0.011
Lrrc4	leucine rich repeat containing 4	0.011
Cd200r2	Cd200 receptor 2	0.011
Reg3b	regenerating islet-derived 3 beta	0.011
Dll4	delta-like 4 (Drosophila)	0.011
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.011
Clec7a	C-type lectin domain family 7, member a	0.011	Rat
Mbnl3	muscleblind-like 3 (Drosophila)	0.011
P2rx5	purinergic receptor P2X, ligand-gated ion channel, 5	0.011
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.011
Serpinb2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.011
RGD1566368	similar to Solute carrier family 6 (neurotransmitter transporter), member 20	0.011
Smcp	sperm mitochondria-associated cysteine-rich protein	0.011
Sgms2	sphingomyelin synthase 2	0.011
Epb41l4b	erythrocyte membrane protein band 4.1 like 4B	0.011
Btg2	BTG family, member 2	0.011
Zpbp2	zona pellucida binding protein 2	0.011
LOC100361706	lambda-chain C1-region-like	0.010
Cyth4	cytohesin 4	0.010
RGD1561343	similar to C20orf118	0.010
Gucy1b2	guanylate cyclase 1, soluble, beta 2	0.010
Vom1r101	vomeronasal 1 receptor 101	0.010
Sp100	SP100 nuclear antigen	0.010
Nox4	NADPH oxidase 4	0.010
RGD1311300	similar to T cell receptor V delta 6	0.010
Clec2d2	C-type lectin domain family 2 member D2	0.010
Creb3l3	cAMP responsive element binding protein 3-like 3	0.010
Phyhip	phytanoyl-CoA 2-hydroxylase interacting protein	0.010
Gpr183	G protein-coupled receptor 183	0.010
RT1-Db1	RT1 class II, locus Db1	0.010
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.010