IMP

Process View

Rattus norvegicus

2 genes annotated in rat

Multi-species View

negative regulation of response to tumor cell

GO:0002835

Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of response to tumor cell"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of response to tumor cell" (in gray)

Name	Description	Probability	Func Analog Organism
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.947
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.804	Rat
Ccr2	chemokine (C-C motif) receptor 2	0.773
Gzmb	granzyme B	0.670
Gzmk	granzyme K	0.654
Igsf6	immunoglobulin superfamily, member 6	0.595
Mmp12	matrix metallopeptidase 12	0.291
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.254
Il7r	interleukin 7 receptor	0.245
Sell	selectin L	0.199
Xcl1	chemokine (C motif) ligand 1	0.195
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.194
Nkg7	natural killer cell group 7 sequence	0.184
Tlr7	toll-like receptor 7	0.184
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.177	Rat
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.172
Ccl4	chemokine (C-C motif) ligand 4	0.159
Prf1	perforin 1 (pore forming protein)	0.151
Rgs1	regulator of G-protein signaling 1	0.148
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.145
Cd72	Cd72 molecule	0.144
Clec12a	C-type lectin domain family 12, member A	0.124
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.120
Slc9a4	solute carrier family 9 (sodium/hydrogen exchanger), member 4	0.111
Ccr5	chemokine (C-C motif) receptor 5	0.106
Sit1	signaling threshold regulating transmembrane adaptor 1	0.105
Cd8a	CD8a molecule	0.103
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.101	Rat
Ccl2	chemokine (C-C motif) ligand 2	0.100
Gzmm	granzyme M (lymphocyte met-ase 1)	0.100
Slamf9	SLAM family member 9	0.085
Serpinb3a	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A	0.082
LOC300024	similar to Ly6-B antigen gene	0.081
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.079
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.075
Clec9a	C-type lectin domain family 9, member a	0.074	Rat
Vom1r93	vomeronasal 1 receptor 93	0.073
RGD1562844	similar to serine (or cysteine) proteinase inhibitor, clade B, member 9	0.071
Itgb2	integrin, beta 2	0.070
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.067
Tcrb	T-cell receptor beta chain	0.066
Zap70	zeta-chain (TCR) associated protein kinase	0.063
Ccl9	chemokine (C-C motif) ligand 9	0.062
Gucy2g	guanylate cyclase 2G	0.059
Klrc2	killer cell lectin-like receptor subfamily C, member 2	0.057	Rat
Ly86	lymphocyte antigen 86	0.057
Pik3cd	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.053
Mcpt8	mast cell protease 8	0.052
Phemx	pan hematopoietic expression	0.051
Klra22	killer cell lectin-like receptor subfamily A, member 22	0.050	Rat
Scin	scinderin	0.049
Serpinb3	serine protease inhibitor B3	0.046
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.046
Ubd	ubiquitin D	0.045
Reg3b	regenerating islet-derived 3 beta	0.044
LOC690020	similar to killer cell lectin-like receptor, subfamily A, member 17	0.042	Rat
Fcer1a	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	0.041
Cst7	cystatin F (leukocystatin)	0.041
Il1rn	interleukin 1 receptor antagonist	0.039
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.038
Tnni3k	TNNI3 interacting kinase	0.038
Cd2	Cd2 molecule	0.037
Hes2	hairy and enhancer of split 2 (Drosophila)	0.036
Spn	sialophorin	0.035
Slpi	secretory leukocyte peptidase inhibitor	0.033
Gpr114	G protein-coupled receptor 114	0.032
Clec4f	C-type lectin domain family 4, member f	0.032
Tfec	transcription factor EC	0.030
Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.030
Fam65b	family with sequence similarity 65, member B	0.030
S100vp	S100 calcium-binding protein, ventral prostate	0.029
Ctsj	cathepsin J	0.029
Ccl5	chemokine (C-C motif) ligand 5	0.029
Gzma	granzyme A	0.029
Skap1	src kinase associated phosphoprotein 1	0.029
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.028
Igfl3	IGF-like family member 3	0.028
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.028
Nox4	NADPH oxidase 4	0.028
Ccl3	chemokine (C-C motif) ligand 3	0.028
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.027
Cd3g	CD3 molecule, gamma	0.027
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.027
Fcgr1a	Fc fragment of IgG, high affinity Ia, receptor (CD64)	0.027
Olr1697	olfactory receptor 1697	0.026
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.026	Rat
Ifng	interferon gamma	0.026
Clec7a	C-type lectin domain family 7, member a	0.026	Rat
Cd247	Cd247 molecule	0.025
Sdr16c5	short chain dehydrogenase/reductase family 16C, member 5	0.025
Vcsa2	variable coding sequence A2	0.024
RGD1304644	similar to RIKEN cDNA 2310046K01	0.024
Il18r1	interleukin 18 receptor 1	0.023
Slfn3	schlafen 3	0.023
Oasl	2'-5'-oligoadenylate synthetase-like	0.023
Fut9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	0.022
Gpr64	G protein-coupled receptor 64	0.022
Krtap13-2	keratin associated protein 13-2	0.022
Stfa2l3	stefin A2-like 3	0.021
LOC100362325	rCG28200-like	0.021
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.021
Zcwpw1	zinc finger, CW-type with PWWP domain 1	0.021
Arhgap15	Rho GTPase activating protein 15	0.021
Stab2	stabilin 2	0.020
Atp6v1g3	ATPase, H+ transporting, lysosomal V1 subunit G3	0.020
Prdm1	PR domain containing 1, with ZNF domain	0.020
Cxcl11	chemokine (C-X-C motif) ligand 11	0.020
Cd69	Cd69 molecule	0.020	Rat
Gfra3	GDNF family receptor alpha 3	0.020
Parvg	parvin, gamma	0.019
Mcpt3	mast cell peptidase 3	0.019
RGD1311300	similar to T cell receptor V delta 6	0.019
Tmem182	transmembrane protein 182	0.019
Prl2b1	Prolactin family 2, subfamily b, member 1	0.018
Rgs14	regulator of G-protein signaling 14	0.018
Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)	0.018
Cd22	CD22 molecule	0.018
Ptgfr	prostaglandin F receptor	0.018
Il1rl1	interleukin 1 receptor-like 1	0.018
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.018
Epsti1	epithelial stromal interaction 1 (breast)	0.018
LOC100363700	probable N-acetyltransferase CML4-like	0.017
Gpx2	glutathione peroxidase 2	0.017
Mcpt4	mast cell protease 4	0.017
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.017
Sh2d1a	SH2 domain protein 1A	0.017
Txk	TXK tyrosine kinase	0.017
Unc5cl	unc-5 homolog C (C. elegans)-like	0.016
Csn2	casein beta	0.016
Zfp37	zinc finger protein 37	0.016
Il2	interleukin 2	0.016
Lilra5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.016
Sh2d2a	SH2 domain protein 2A	0.015
Adam7	ADAM metallopeptidase domain 7	0.015
Cd4	Cd4 molecule	0.015
Kcnv1	potassium channel, subfamily V, member 1	0.015
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.015
Chrm5	cholinergic receptor, muscarinic 5	0.015
LOC100361053	mCG1039741-like	0.014
Cyp7b1	cytochrome P450, family 7, subfamily b, polypeptide 1	0.014
Slc22a25	solute carrier family 22, member 25	0.014
Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.014
Cd244	Cd244 molecule, natural killer cell receptor 2B4	0.014
Gen1	Gen homolog 1, endonuclease (Drosophila)	0.014
Faslg	Fas ligand (TNF superfamily, member 6)	0.014
Plin5	perilipin 5	0.014
Clec1a	C-type lectin domain family 1, member a	0.014	Rat
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.014
Oprm1	opioid receptor, mu 1	0.013
Cd200r2	Cd200 receptor 2	0.013
Rps27	ribosomal protein S27	0.013
Vom1r102	vomeronasal 1 receptor 102	0.013
Fsd2	fibronectin type III and SPRY domain containing 2	0.013
Prl2a1	Prolactin family 2, subfamily a, member 1	0.013
Cela1	chymotrypsin-like elastase family, member 1	0.013
Dmbt1	deleted in malignant brain tumors 1	0.013
Reg3g	regenerating islet-derived 3 gamma	0.013
Gimap4	GTPase, IMAP family member 4	0.013
Phyhip	phytanoyl-CoA 2-hydroxylase interacting protein	0.012
Lrrc4	leucine rich repeat containing 4	0.012
Slc28a3	solute carrier family 28 (sodium-coupled nucleoside transporter), member 3	0.012
MGC105649	hypothetical LOC302884	0.012
Cyp39a1	cytochrome P450, family 39, subfamily a, polypeptide 1	0.012
Slc17a1	solute carrier family 17 (sodium phosphate), member 1	0.012
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.012
Cftr	cystic fibrosis transmembrane conductance regulator homolog (human)	0.012
Apcs	amyloid P component, serum	0.012
Tchh	trichohyalin	0.012
Slc6a12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.012
Ly6al	lymphocyte antigen 6 complex, locus A-like	0.012
LOC687856	similar to Myeloid cell surface antigen CD33 precursor (Siglec-3)	0.012
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.011
Inpp4b	inositol polyphosphate-4-phosphatase, type II	0.011
Klre1	killer cell lectin-like receptor, family E, member 1	0.011
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.011
Dppa3	developmental pluripotency-associated 3	0.011
RGD1566368	similar to Solute carrier family 6 (neurotransmitter transporter), member 20	0.011
Spp1	secreted phosphoprotein 1	0.011
Myocd	myocardin	0.011
Card6	caspase recruitment domain family, member 6	0.011
Tmem8c	transmembrane protein 8C	0.011
C6	complement component 6	0.011
Lrrc8c	leucine rich repeat containing 8 family, member C	0.011
Ch25h	cholesterol 25-hydroxylase	0.011
Prl8a7	prolactin family 8, subfamily a, member 7	0.010
Cxcl10	chemokine (C-X-C motif) ligand 10	0.010
Uba7	ubiquitin-like modifier activating enzyme 7	0.010
Plscr2	phospholipid scramblase 2	0.010
Ccr1	chemokine (C-C motif) receptor 1	0.010
Mageb16	melanoma antigen family B, 16	0.010
LOC679551	similar to MIC2 like 1	0.010
Scel	sciellin	0.010
LOC494538	ABP beta	0.010
Bin2	bridging integrator 2	0.010
Myo1f	myosin IF	0.010
LOC100361706	lambda-chain C1-region-like	0.010