IMP

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Rattus norvegicus

20 genes annotated in rat

acute phase response

An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "acute phase response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "acute phase response" (in gray)

Name	Description	Probability	Func Analog Organism
Il1b	interleukin 1 beta	0.754
RT1-EC2	RT1 class Ib, locus EC2	0.499
Cd14	CD14 molecule	0.467
Cxcl10	chemokine (C-X-C motif) ligand 10	0.453
Il1a	interleukin 1 alpha	0.332
Il6	interleukin 6	0.243
Socs3	suppressor of cytokine signaling 3	0.219
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.218
Cxcl2	chemokine (C-X-C motif) ligand 2	0.212
Mmp12	matrix metallopeptidase 12	0.200
Mgst2	microsomal glutathione S-transferase 2	0.191
Cp	ceruloplasmin	0.188
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.154	Rat
C3	complement component 3	0.146
Il1rn	interleukin 1 receptor antagonist	0.141
Ccl2	chemokine (C-C motif) ligand 2	0.141
Klk6	kallikrein related-peptidase 6	0.138
Il1r2	interleukin 1 receptor, type II	0.135
Ptgs2	prostaglandin-endoperoxide synthase 2	0.129
Ccl4	chemokine (C-C motif) ligand 4	0.128	Rat
Il1r1	interleukin 1 receptor, type I	0.126
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.120
Pctp	phosphatidylcholine transfer protein	0.119
Rab34	RAB34, member RAS oncogene family	0.116
Ccl3	chemokine (C-C motif) ligand 3	0.115	Rat
Cfb	complement factor B	0.115
LOC100361547	Cytochrome P450, family 2, subfamily c, polypeptide 7-like	0.112
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.109
Gc	group specific component	0.097
C1qc	complement component 1, q subcomponent, C chain	0.089
Gsta5	glutathione S-transferase Yc2 subunit	0.087
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.086
LOC679840	similar to germinal histone H4 gene	0.086
LOC100364500	RT1 class I, locus CE11-like	0.086
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.084
Hpx	hemopexin	0.078
Tfec	transcription factor EC	0.077
Met	met proto-oncogene	0.074
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.073
RT1-S3	RT1 class Ib, locus S3	0.072	Rat
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.072
LOC100363106	LRRG00130-like	0.070
Gzmb	granzyme B	0.069
Plg	plasminogen	0.069
Casp1	caspase 1	0.066
Apob	apolipoprotein B	0.065
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.063
Akr1c14	aldo-keto reductase family 1, member C14	0.062
Calcrl	calcitonin receptor-like	0.062
Zfp260	zinc finger protein 260	0.059
Ccl20	chemokine (C-C motif) ligand 20	0.058	Rat
Cfi	complement factor I	0.055
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.054
Sell	selectin L	0.053
Dnm1l	dynamin 1-like	0.051
Vcsa2	variable coding sequence A2	0.050
Birc3	baculoviral IAP repeat-containing 3	0.049
Spink1	serine peptidase inhibitor, Kazal type 1	0.048
Anpep	alanyl (membrane) aminopeptidase	0.046
Mmp3	matrix metallopeptidase 3	0.044
Prf1	perforin 1 (pore forming protein)	0.043
Rag1	recombination activating gene 1	0.041
Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase	0.039
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.039	Rat
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.039
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.038
Lst1	leukocyte specific transcript 1	0.038
Cd86	CD86 molecule	0.038
Calcr	calcitonin receptor	0.038
Icam1	intercellular adhesion molecule 1	0.036
Srd5a1	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	0.036
Ccl7	chemokine (C-C motif) ligand 7	0.035	Rat
Pgr	progesterone receptor	0.034
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.033
Plau	plasminogen activator, urokinase	0.033
F13a1	coagulation factor XIII, A1 polypeptide	0.033
Mx1	myxovirus (influenza virus) resistance 1	0.032
Fgg	fibrinogen gamma chain	0.031
Spink3	serine peptidase inhibitor, Kazal type 3	0.031
Rab32	RAB32, member RAS oncogene family	0.031
Aqp9	aquaporin 9	0.031
Tgm1	transglutaminase 1, K polypeptide	0.031
Tat	tyrosine aminotransferase	0.030
Sult1c3	sulfotransferase family, cytosolic, 1C, member 3	0.029
Gabra5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.029
LOC100359522	LRRGT00191-like	0.029
Dock8	dedicator of cytokinesis 8	0.029
Il9r	interleukin 9 receptor	0.029
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.028
Fosl1	fos-like antigen 1	0.028
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.028
Myd88	myeloid differentiation primary response gene 88	0.027
Clcn5	chloride channel 5	0.027
Mug1	murinoglobulin 1	0.027	Rat
Irf2	interferon regulatory factor 2	0.027
Apoa5	apolipoprotein A-V	0.026
Tcf21	transcription factor 21	0.026
Iapp	islet amyloid polypeptide	0.026
Prrx1	paired related homeobox 1	0.026
Gfap	glial fibrillary acidic protein	0.026
Cps1	carbamoyl-phosphate synthetase 1	0.025
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.025
Sult2al1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1	0.025
Gcg	glucagon	0.025
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.024
Nkg7	natural killer cell group 7 sequence	0.024
Serpinb9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.024
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.024
LOC100361864	UDP-glucuronosyltransferase 2B3-like	0.024
Vom1r100	vomeronasal 1 receptor 100	0.024
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.023
Ednrb	endothelin receptor type B	0.023
Ugt1a5	UDP glucuronosyltransferase 1 family, polypeptide A5	0.023	Rat
RT1-CE12	RT1 class I, locus CE12	0.023
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.023
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.023
Kif6	kinesin family member 6	0.023
Tlr2	toll-like receptor 2	0.023
Reg1a	regenerating islet-derived 1 alpha	0.023
Cpb1	carboxypeptidase B1 (tissue)	0.023
Lcn2	lipocalin 2	0.023
Apol3	apolipoprotein L, 3	0.023
Neurl3	neuralized homolog 3 (Drosophila)	0.022
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.022
Abcb1b	ATP-binding cassette, subfamily B (MDR/TAP), member 1B	0.022
Agtr1a	angiotensin II receptor, type 1a	0.022
Vom2r32	vomeronasal 2 receptor, 32	0.022
Ccl11	chemokine (C-C motif) ligand 11	0.022	Rat
Olr1697	olfactory receptor 1697	0.022
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.021
Fut2	fucosyltransferase 2 (secretor status included)	0.021
C2	complement component 2	0.021
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.021
LOC100365195	rCG64293-like	0.021
Kng2	kininogen 2	0.021
Fgfr2	fibroblast growth factor receptor 2	0.021
Atp1a4	ATPase, Na+/K+ transporting, alpha 4 polypeptide	0.021
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.021
Cyp2b2	cytochrome P450, family 2, subfamily b, polypeptide 2	0.021
Plp1	proteolipid protein 1	0.020
Il2rb	interleukin 2 receptor, beta	0.020
Alb	albumin	0.020
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.020
Kap	kidney androgen regulated protein	0.020
Xcl1	chemokine (C motif) ligand 1	0.020	Rat
LOC293989	cytochrome P450-like	0.020
Prl8a4	prolactin family 8, subfamily a, member 4	0.019
RT1-DOb	RT1 class II, locus DOb	0.019
Clec4f	C-type lectin domain family 4, member f	0.019
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.019
Irf1	interferon regulatory factor 1	0.019
Ifi35	interferon-induced protein 35	0.019
Serpina1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.019
Usp9x	ubiquitin specific peptidase 9, X-linked	0.019
Tmem176b	transmembrane protein 176B	0.019
Sele	selectin E	0.019
Myf6	myogenic factor 6	0.019
Igtp	interferon gamma induced GTPase	0.019
Il1rap	interleukin 1 receptor accessory protein	0.018
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.018
Mbl2	mannose-binding lectin (protein C) 2	0.018
Ugt1a3	UDP glycosyltransferase 1 family, polypeptide A3	0.018	Rat
Il4	interleukin 4	0.018
Gzma	granzyme A	0.018
Ptgfr	prostaglandin F receptor	0.018
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.018
Snai2	snail homolog 2 (Drosophila)	0.018
F9	coagulation factor IX	0.017
Cyp2c22	cytochrome P450, family 2, subfamily c, polypeptide 22	0.017
Oas1a	2'-5' oligoadenylate synthetase 1A	0.017
Cxcl9	chemokine (C-X-C motif) ligand 9	0.017
Il5	interleukin 5	0.017
Man2c1	mannosidase, alpha, class 2C, member 1	0.017
Fga	fibrinogen alpha chain	0.017
Gabrp	gamma-aminobutyric acid (GABA-A) receptor, pi	0.017
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.017
LOC100364485	mCG1051031-like	0.017
Ugt1a2	UDP glucuronosyltransferase 1 family, polypeptide A2	0.017	Rat
Gzmk	granzyme K	0.016
Olr1082	olfactory receptor 1082	0.016
Dmgdh	dimethylglycine dehydrogenase	0.016
Ces1c	carboxylesterase 1C	0.016
Kcnj16	potassium inwardly-rectifying channel, subfamily J, member 16	0.016
Rxra	retinoid X receptor alpha	0.016
A1i3	alpha-1-inhibitor III	0.016
Ccr2	chemokine (C-C motif) receptor 2	0.016
Hoxb8	homeo box B8	0.016
Parp14	poly (ADP-ribose) polymerase family, member 14	0.016
Flg	filaggrin	0.016
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.016
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.015
Il1rl1	interleukin 1 receptor-like 1	0.015
F10	coagulation factor X	0.015
Pim1	pim-1 oncogene	0.015
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.015
Grpcb	glutamine/glutamic acid-rich protein A	0.015
S1pr1	sphingosine-1-phosphate receptor 1	0.015	Rat
L3mbtl3	l(3)mbt-like 3 (Drosophila)	0.014
Bcl3	B-cell CLL/lymphoma 3	0.014
Creb1	cAMP responsive element binding protein 1	0.014
Slco1a5	solute carrier organic anion transporter family, member 1a5	0.014
RT1-A3	RT1 class I, locus A3	0.014
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.014
Mcpt8	mast cell protease 8	0.014
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.014
Adamts4	ADAM metallopeptidase with thrombospondin type 1 motif, 4	0.014
Proc	protein C	0.014
Egfr	epidermal growth factor receptor	0.014
Serpinc1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.014
Cd2	Cd2 molecule	0.014
Olr1468	olfactory receptor 1468	0.013
Il4ra	interleukin 4 receptor, alpha	0.013
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.013
Ugt1a7c	UDP glucuronosyltransferase 1 family, polypeptide A7C	0.013	Rat
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.013	Rat
Gabra2	gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2	0.013
Cdh17	cadherin 17	0.013
Ugt2b37	UDP-glucuronosyltransferase 2 family, member 37	0.013	Rat
Grem1	gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)	0.013
Dctn1	dynactin 1	0.013
Mbp	myelin basic protein	0.013
Mocs3	molybdenum cofactor synthesis 3	0.013
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.013
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.013
Nox4	NADPH oxidase 4	0.013
Fabp1	fatty acid binding protein 1, liver	0.013
Reg3b	regenerating islet-derived 3 beta	0.013
Mapk4	mitogen-activated protein kinase 4	0.013
Hpgds	hematopoietic prostaglandin D synthase	0.013
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.013
Irf7	interferon regulatory factor 7	0.012
LOC100364265	ribosomal protein L19-like	0.012
Hck	hemopoietic cell kinase	0.012
Slc17a3	solute carrier family 17 (sodium phosphate), member 3	0.012
Ppp3r2	protein phosphatase 3, regulatory subunit B, beta isoform	0.012
Prl7a3	prolactin family 7, subfamily a, member 3	0.012
Ier3	immediate early response 3	0.012
Adora3	adenosine A3 receptor	0.012
Amy2	amylase 2, pancreatic	0.012
Rab19	RAB19, member RAS oncogene family	0.012
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.012
Gch1	GTP cyclohydrolase 1	0.012
Gabra1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.012
Ccr1	chemokine (C-C motif) receptor 1	0.012
Hnmt	histamine N-methyltransferase	0.012
Il10	interleukin 10	0.012
Cckar	cholecystokinin A receptor	0.012
Orm1	orosomucoid 1	0.012
Folh1	folate hydrolase 1	0.012	Rat
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.012
Ccdc3	coiled-coil domain containing 3	0.012
Il18bp	interleukin 18 binding protein	0.011
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.011
Acvr1c	activin A receptor, type IC	0.011
Apba1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.011
Ugt1a1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.011
Pros1	protein S (alpha)	0.011
Vcan	versican	0.011
Fetub	fetuin B	0.011
Itgam	integrin, alpha M	0.011
Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	0.011
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.011
Trim5	tripartite motif-containing 5	0.011
Il15	interleukin 15	0.011
Cd247	Cd247 molecule	0.011
Bid	BH3 interacting domain death agonist	0.011
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.011
Il2	interleukin 2	0.011
Rarres1	retinoic acid receptor responder (tazarotene induced) 1	0.011
Dok2	docking protein 2	0.011
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.010	Mouse
RGD1305793	similar to hypothetical protein FLJ20154	0.010
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.010
Sert1	Sertoli cell protein 1	0.010
Smcp	sperm mitochondria-associated cysteine-rich protein	0.010
Il7	interleukin 7	0.010
Csn1s2a	casein alpha s2-like A	0.010
Syt10	synaptotagmin X	0.010
RGD1564865	similar to 20-alpha-hydroxysteroid dehydrogenase	0.010
Gucy2d	guanylate cyclase 2d	0.010
Abcc3	ATP-binding cassette, subfamily C (CFTR/MRP), member 3	0.010
Keg1	kidney expressed gene 1	0.010
Ces1e	carboxylesterase 1E	0.010
Vom1r101	vomeronasal 1 receptor 101	0.010
Ppap2b	phosphatidic acid phosphatase type 2B	0.010
Slc22a18	solute carrier family 22, member 18	0.010
RT1-M3-1	RT1 class Ib, locus M3, gene 1	0.010	Rat
Col4a3	collagen, type IV, alpha 3	0.010