IMP

Process View

Caenorhabditis elegans

2 genes annotated in worm

Multi-species View

inactivation of mapkkk activity

GO:0051390

Any process that terminates the activity of the active enzyme MAP kinase kinase kinase (MAPKKK).

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Known genes in the process in worm Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "inactivation of mapkkk activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "inactivation of mapkkk activity" (in gray)

Name	Description	Probability	Func Analog Organism
inx-12	Protein INX-12	0.681	Worm
CELE_Y75B12B.1	Protein Y75B12B.1	0.519
R148.4	Protein R148.4	0.457
glr-5	Protein GLR-5	0.426
inx-5	Protein INX-5	0.367
inx-13	Protein INX-13	0.352	Worm
unc-36	Protein UNC-36	0.352
sdz-28	Protein SDZ-28	0.347
che-3	Protein CHE-3	0.328
unc-7	Protein UNC-7	0.320	Worm
C48B4.8	Protein C48B4.8	0.289
mec-2	Protein MEC-2	0.271
ifd-1	Protein IFD-1	0.269
efn-2	Protein EFN-2	0.219
eat-4	Protein EAT-4	0.190
rad-51	Protein RAD-51	0.188
unc-86	Protein UNC-86	0.186
inx-15	Protein INX-15	0.182	Worm
T23G4.3	Protein T23G4.3	0.172
tbh-1	Protein TBH-1	0.169
vha-7	Protein VHA-7	0.168
vha-17	Protein VHA-17	0.159
nhr-91	Protein NHR-91	0.155
unc-29	Protein UNC-29	0.152
hlh-2	Protein HLH-2	0.144
K04G2.9	Protein K04G2.9	0.137
Y87G2A.11	Protein Y87G2A.11	0.135
CELE_ZC513.5	Protein ZC513.5	0.113
F14B8.6	Protein F14B8.6	0.111
C14A4.6	Protein C14A4.6	0.109
F18F11.1	Protein F18F11.1	0.104
inx-4	Protein INX-4	0.104	Worm
ztf-30	Protein ZTF-30	0.102
CELE_C27A7.6	Protein C27A7.6	0.102
nlg-1	Protein NLG-1	0.101
twk-18	Protein TWK-18	0.099
ape-1	Protein APE-1	0.096
vab-3	Protein VAB-3	0.092
C48E7.1	Protein C48E7.1	0.083
aqp-2	Protein AQP-2	0.082
CELE_C01G6.3	Protein C01G6.3	0.080
inx-17	Protein INX-17	0.080	Worm
che-2	Protein CHE-2	0.078
acs-19	Protein ACS-19	0.066
pat-6	Protein PAT-6	0.065
clc-3	Protein CLC-3	0.065
acl-14	Protein ACL-14	0.065
aqp-10	Protein AQP-10	0.062
CELE_Y39E4B.5	Protein Y39E4B.5	0.061
vha-4	Protein VHA-4	0.060
F19C6.5	Protein F19C6.5	0.060
F44E2.10	Protein F44E2.10	0.059
R13A5.9	Protein R13A5.9	0.057
F39G3.5	Protein F39G3.5	0.055
inx-22	Protein INX-22	0.051	Worm
scav-6	Protein SCAV-6	0.048
mpz-2	Protein MPZ-2	0.048
inx-2	Protein INX-2	0.046
tbb-4	Protein TBB-4	0.046
CELE_Y51A2D.14	Protein Y51A2D.14	0.045
hsp-12.1	Protein HSP-12.1	0.045
rig-5	Protein RIG-5	0.044
CELE_K01D12.6	Protein K01D12.6	0.043
C05E7.3	Protein C05E7.3	0.043
F48E3.4	Protein F48E3.4	0.043
nhr-31	Protein NHR-31	0.042
rlbp-1	Protein RLBP-1	0.042
CELE_F35E12.9	Protein F35E12.9	0.040
prmt-3	Protein PRMT-3	0.040
klp-15	Protein KLP-15	0.040
ced-8	Protein CED-8	0.040
lev-8	Protein LEV-8	0.040
R02F2.4	Protein R02F2.4	0.038
K10D6.2	Protein K10D6.2	0.038	Worm
sng-1	Protein SNG-1	0.037
nmgp-1	Protein NMGP-1	0.037
cyk-7	Protein CYK-7	0.035
daf-10	Protein DAF-10	0.035
W02B8.2	Protein W02B8.2	0.035
bath-36	Protein BATH-36	0.035
R03H10.2	Protein R03H10.2	0.034
sul-2	Protein SUL-2	0.034
CELE_C39H7.4	Protein C39H7.4	0.034
C38C10.2	Protein C38C10.2	0.034
CELE_Y44A6D.3	Protein Y44A6D.3	0.034
unc-47	Protein UNC-47	0.034
ger-1	Protein GER-1	0.033
CELE_T07C12.12	Protein T07C12.12	0.033
ZK470.1	Protein ZK470.1	0.033
C49A9.5	Protein C49A9.5	0.033
lbp-3	Protein LBP-3	0.033
skr-13	Protein SKR-13	0.032
C46C11.3	Protein C46C11.3	0.032
upp-1	Protein UPP-1	0.032
cam-1	Protein CAM-1	0.032
Y54G2A.36	Protein Y54G2A.36	0.032
cav-2	Protein CAV-2	0.032
cng-4	Protein CNG-4	0.031
hst-6	Protein HST-6	0.031
CELE_Y43D4A.3	Protein Y43D4A.3	0.031
CELE_ZC204.12	Protein ZC204.12	0.030
che-1	Protein CHE-1	0.029
F35C11.5	Protein F35C11.5	0.029
M03C11.6	Protein M03C11.6	0.029
W01D2.5	Protein W01D2.5	0.029
CELE_Y14H12B.2	Protein Y14H12B.2	0.028
dct-18	Protein DCT-18	0.028
unc-1	Protein UNC-1	0.027
R10H10.3	Protein R10H10.3	0.027
T21C9.6	Protein T21C9.6	0.027
ZK1053.4	Protein ZK1053.4	0.026
bath-7	Protein BATH-7	0.026
rod-1	Protein ROD-1	0.026
lbp-7	Protein LBP-7	0.025
pes-2.1	Protein PES-2.1	0.025
T27A3.6	Protein T27A3.6	0.025
cav-1	Protein CAV-1	0.024
math-40	Protein MATH-40	0.024
nsy-4	Protein NSY-4	0.024
grl-1	Protein GRL-1	0.024
prl-1	Protein PRL-1	0.024
Y62H9A.5	Protein Y62H9A.5	0.023
unc-42	Protein UNC-42	0.023
C44B7.11	Protein C44B7.11	0.023
cgt-1	Protein CGT-1	0.023
Y62H9A.3	Protein Y62H9A.3	0.023
lgc-34	Protein LGC-34	0.023
oct-2	Protein OCT-2	0.023
unc-8	Protein UNC-8	0.022
pitp-1	Protein PITP-1	0.022
CELE_C05B5.4	Protein C05B5.4	0.022
sol-1	Protein SOL-1	0.022
mec-1	Protein MEC-1	0.022
Y65B4BL.4	Protein Y65B4BL.4	0.022
pdfr-1	Protein PDFR-1	0.022
W10C8.4	Protein W10C8.4	0.021
T04G9.7	Protein T04G9.7	0.021
CELE_C39E9.10	Protein C39E9.10	0.021
lsl-1	Protein LSL-1	0.021
unc-115	Protein UNC-115	0.021
K01A2.9	Protein K01A2.9	0.020
C47D12.5	Protein C47D12.5	0.020
ncs-2	Protein NCS-2	0.020
C24A3.2	Protein C24A3.2	0.020
pbo-4	Protein PBO-4	0.019
cyb-2.2	Protein CYB-2.2	0.019
daf-6	Protein DAF-6	0.019
T20D3.5	Protein T20D3.5	0.018
CELE_F36H12.16	Protein F36H12.16	0.018
vha-10	Protein VHA-10	0.018
lgc-54	Protein LGC-54	0.018
fbxa-203	Protein FBXA-203	0.018
CELE_F11A5.9	Protein F11A5.9	0.018
F49E12.1	Protein F49E12.1	0.018
C03A3.1	Protein C03A3.1	0.018
fax-1	Protein FAX-1	0.018
M153.2	Protein M153.2	0.018
CELE_Y48G1BM.1	Protein Y48G1BM.1	0.018
C29F5.1	Protein C29F5.1	0.017
CELE_C08B6.11	Protein C08B6.11	0.017
lin-11	Protein LIN-11	0.017
F20C5.3	Protein F20C5.3	0.017
rab-3	Protein RAB-3	0.017
Y71F9AL.8	Protein Y71F9AL.8	0.017
nrde-3	Protein NRDE-3	0.017
shw-3	Protein SHW-3	0.017
CELE_Y44A6D.2	Protein Y44A6D.2	0.017
nphp-4	Protein NPHP-4	0.017
F36F2.1	Protein F36F2.1	0.016
C44B7.5	Protein C44B7.5	0.016
cpg-3	Protein CPG-3	0.016
F45E1.1	Protein F45E1.1	0.016
F21G4.1	Protein F21G4.1	0.016
nid-1	Protein NID-1	0.016
C05E11.6	Protein C05E11.6	0.016
srx-47	Protein SRX-47	0.016
nlp-36	Protein NLP-36	0.016
heh-1	Protein HEH-1	0.016
CELE_C25A1.5	Protein C25A1.5	0.016
CELE_ZK829.9	Protein ZK829.9	0.016
sre-7	Protein SRE-7	0.016
clec-222	Protein CLEC-222	0.016
F40A3.4	Protein F40A3.4	0.016
tba-9	Protein TBA-9	0.016
CELE_F57G9.3	Protein F57G9.3	0.016
ZK813.3	Protein ZK813.3	0.015
T10B11.5	Protein T10B11.5	0.015
C49A9.6	Protein C49A9.6	0.015
F53B3.5	Protein F53B3.5	0.015
C49A1.10	Protein C49A1.10	0.015
Y55F3AM.5	Protein Y55F3AM.5	0.015
C08G9.2	Protein C08G9.2	0.015
clec-15	Protein CLEC-15	0.015
dhs-21	Protein DHS-21	0.015
hda-11	Protein HDA-11	0.015
ZK813.1	Protein ZK813.1	0.015
snf-11	Protein SNF-11	0.015
K01A2.5	Protein K01A2.5	0.015
glr-1	Protein GLR-1	0.015
ddo-3	Protein DDO-3	0.015
F55G1.15	Protein F55G1.15	0.015
T19A6.1	Protein T19A6.1	0.014
vit-6	Protein VIT-6	0.014
T03F7.7	Protein T03F7.7	0.014
egl-19	Protein EGL-19	0.014
cln-3.1	Protein CLN-3.1	0.014
hpo-4	Protein HPO-4	0.014
plx-2	Protein PLX-2	0.014
CELE_M176.5	Protein M176.5	0.014
ung-1	Protein UNG-1	0.014
F57B1.1	Protein F57B1.1	0.014
ser-2	Protein SER-2	0.014
pfn-3	Protein PFN-3	0.014
col-165	Protein COL-165	0.013
H10E21.1	Protein H10E21.1	0.013
zag-1	Protein ZAG-1	0.013
T05H10.4	Protein T05H10.4	0.013
C31H5.6	Protein C31H5.6	0.013
sru-40	Protein SRU-40	0.013
T28B4.4	Protein T28B4.4	0.013
elp-1	Protein ELP-1	0.013
vha-15	Protein VHA-15	0.013
aqp-4	Protein AQP-4	0.013
CELE_K08E7.8	Protein K08E7.8	0.013
gcy-18	Protein GCY-18	0.013
F53H8.3	Protein F53H8.3	0.013
T05C12.4	Protein T05C12.4	0.013
CELE_F40F9.5	Protein F40F9.5	0.013
oig-1	Protein OIG-1	0.013
T09B4.8	Protein T09B4.8	0.013
F14F4.1	Protein F14F4.1	0.013
Y110A7A.2	Protein Y110A7A.2	0.013
gsto-1	Protein GSTO-1	0.013
ref-1	Protein REF-1	0.013
CELE_K02E7.6	Protein K02E7.6	0.013
bath-41	Protein BATH-41	0.013
pes-1	Protein PES-1	0.013
C50D2.2	Protein C50D2.2	0.013
R13H4.7	Protein R13H4.7	0.013
acc-4	Protein ACC-4	0.012
atg-16.1	Protein ATG-16.1	0.012
gyg-2	Protein GYG-2	0.012
col-40	Protein COL-40	0.012
cutl-6	Protein CUTL-6	0.012
C25A8.4	Protein C25A8.4	0.012
cysl-1	Protein CYSL-1	0.012
nhr-134	Protein NHR-134	0.012
T22B2.3	Protein T22B2.3	0.012
tub-1	Protein TUB-1	0.012
eri-5	Protein ERI-5	0.012
CELE_F23H12.7	Protein F23H12.7	0.012
vha-5	Protein VHA-5	0.012
bre-2	Protein BRE-2	0.012
inx-11	Protein INX-11	0.012
C35D10.12	Protein C35D10.12	0.012
CELE_R13D11.4	Protein R13D11.4	0.012
F29B9.8	Protein F29B9.8	0.012
mop-25.3	Protein MOP-25.3	0.012
unc-25	Protein UNC-25	0.012
srh-223	Protein SRH-223	0.011
cnd-1	Protein CND-1	0.011
sft-4	Protein SFT-4	0.011
F11G11.5	Protein F11G11.5	0.011
B0207.2	Protein B0207.2	0.011
CELE_Y45F3A.4	Protein Y45F3A.4	0.011
mei-2	Protein MEI-2	0.011
C53B4.3	Protein C53B4.3	0.011
CELE_T07C12.9	Protein T07C12.9	0.011
dve-1	Protein DVE-1	0.011
grl-13	Protein GRL-13	0.011
str-166	Protein STR-166	0.011
F56C11.5	Protein F56C11.5	0.011
chk-1	Protein CHK-1	0.011
ahr-1	Protein AHR-1	0.011
F08F3.1	Protein F08F3.1	0.011
CELE_ZC513.1	Protein ZC513.1	0.011
C50F7.1	Protein C50F7.1	0.011
CELE_Y111B2A.19	Protein Y111B2A.19	0.011
skr-7	Protein SKR-7	0.011
mec-12	Protein MEC-12	0.011
aex-2	Protein AEX-2	0.011
ceh-32	Protein CEH-32	0.011
srb-3	Protein SRB-3	0.011
C56G2.3	Protein C56G2.3	0.011
CELE_F49H6.13	Protein F49H6.13	0.011
npr-10	Protein NPR-10	0.011
ZK616.5	Protein ZK616.5	0.011
set-27	Protein SET-27	0.011
lin-3	Protein LIN-3	0.011
tag-256	Protein TAG-256	0.011
CELE_ZK896.1	Protein ZK896.1	0.011
Y48C3A.20	Protein Y48C3A.20	0.010
nhr-38	Protein NHR-38	0.010
ocr-1	Protein OCR-1	0.010
D1081.9	Protein D1081.9	0.010
CELE_F54D7.2	Protein F54D7.2	0.010
CELE_Y41E3.3	Protein Y41E3.3	0.010
K08E4.3	Protein K08E4.3	0.010
cas-2	Protein CAS-2	0.010
set-23	Protein SET-23	0.010
W02D9.9	Protein W02D9.9	0.010
C02F5.6	Protein C02F5.6	0.010
srt-70	Protein SRT-70	0.010
F08F3.6	Protein F08F3.6	0.010
inx-6	Protein INX-6	0.010	Worm
CELE_Y48G1BL.6	Protein Y48G1BL.6	0.010
daf-36	Protein DAF-36	0.010
T01C3.9	Protein T01C3.9	0.010
srd-55	Protein SRD-55	0.010
D1007.10	Protein D1007.10	0.010
syg-1	Protein SYG-1	0.010
CELE_C49C3.9	Protein C49C3.9	0.010
nhr-100	Protein NHR-100	0.010
F45E4.5	Protein F45E4.5	0.010
M28.8	Protein M28.8	0.010
vab-9	Protein VAB-9	0.010
R07B1.8	Protein R07B1.8	0.010
F17A9.5	Protein F17A9.5	0.010
clec-227	Protein CLEC-227	0.010
F52C9.5	Protein F52C9.5	0.010
cfz-2	Protein CFZ-2	0.010
C39D10.2	Protein C39D10.2	0.010