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Process View

Danio rerio

1 genes annotated in zebrafish

mesodermal to mesenchymal transition involved in gastrulation

The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesodermal to mesenchymal transition involved in gastrulation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mesodermal to mesenchymal transition involved in gastrulation" (in gray)

Name	Description	Probability	Func Analog Organism
tbx16	T-box gene 16	0.974
shha	sonic hedgehog a	0.937
flh	floating head	0.903
myl7	myosin, light polypeptide 7, regulatory	0.876
chd	chordin	0.869
bmp4	bone morphogenetic protein 4	0.741
lft1	lefty1	0.733
ntla	no tail a	0.724	Zebrafish
bmp2b	bone morphogenetic protein 2b	0.701
fgf8a	fibroblast growth factor 8 a	0.693
tbx5a	T-box 5a	0.663	Zebrafish
tbx20	T-box 20	0.631	Zebrafish
ptch1	patched 1	0.594
foxh1	forkhead box H1	0.592
her7	hairy and enhancer of split related-7	0.561
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.506
has2	hyaluronan synthase 2	0.482
tbx2a	T-box gene 2a	0.476	Zebrafish
cdh2	cadherin 2, neuronal	0.469
nkx2.5	NK2 transcription factor related 5	0.458
hnf1ba	HNF1 homeobox Ba	0.390
eve1	even-skipped-like1	0.368
ndr2	nodal-related 2	0.349
hand2	heart and neural crest derivatives expressed transcript 2	0.317
gsc	goosecoid	0.311
mib	mind bomb	0.310
lft2	lefty2	0.292
prdm1a	PR domain containing 1a, with ZNF domain	0.262
tbx6	T-box gene 6	0.256	Zebrafish
fgf3	fibroblast growth factor 3	0.242
wnt11	wingless-type MMTV integration site family, member 11	0.242
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.240
oep	one-eyed pinhead	0.231
cdx4	caudal type homeo box transcription factor 4	0.211
fli1a	friend leukemia integration 1a	0.201
mef2ca	myocyte enhancer factor 2ca	0.182
pkd2	polycystic kidney disease 2	0.182
fn1	fibronectin 1	0.175
tcf21	transcription factor 21	0.154
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.153
tbx2b	T-box 2b	0.144	Zebrafish
dharma	dharma	0.116
drl	draculin	0.109
pax2a	paired box gene 2a	0.100
dlx2a	distal-less homeobox gene 2a	0.097
cyp26a1	cytochrome P450, subfamily XXVIA, polypeptide 1	0.096
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.094
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.094
smo	smoothened homolog (Drosophila)	0.091
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.089
tbx3	T-box 3	0.088	Zebrafish
cmlc1	cardiac myosin light chain-1	0.084
fgf10a	fibroblast growth factor 10a	0.080
myod1	myogenic differentiation 1	0.078
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.076
her1	hairy-related 1	0.070
vent	ventral expressed homeobox	0.069
pou5f1	POU domain, class 5, transcription factor 1	0.069
foxi1	forkhead box I1	0.067
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.064
eomesa	eomesodermin homolog a	0.063	Zebrafish Mouse
tbx1	T-box 1	0.062	Zebrafish
runx1	runt-related transcription factor 1	0.061
tll1	tolloid-like 1	0.060
trim33	tripartite motif-containing 33	0.059
foxa1	forkhead box A1	0.057
sox32	SRY-box containing gene 32	0.057
lhx1a	LIM homeobox 1a	0.055
tal1	T-cell acute lymphocytic leukemia 1	0.054
dld	deltaD	0.053
otx2	orthodenticle homolog 2	0.051
spns2	spinster homolog 2 (Drosophila)	0.051
wnt5b	wingless-type MMTV integration site family, member 5b	0.051
pcdh8	protocadherin 8	0.051
tfap2a	transcription factor AP-2 alpha	0.050
isl2a	islet2a	0.050
synpo2lb	synaptopodin 2-like b	0.047
notch1a	notch homolog 1a	0.047
foxa3	forkhead box A3	0.047
hoxa9a	homeo box A9a	0.045
snai1a	snail homolog 1a (Drosophila)	0.043
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.043
dbx1b	developing brain homeobox 1b	0.039
tbx18	T-box 18	0.036	Zebrafish
sesn1	sestrin 1	0.035
msgn1	mesogenin 1	0.034
gli2a	GLI-Kruppel family member GLI2a	0.034
tgfb3	transforming growth factor, beta 3	0.034
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.034
crip2	cysteine-rich protein 2	0.033
gbx2	gastrulation brain homeo box 2	0.033
isl1	islet1	0.032
tbx5b	T-box 5b	0.031
fzd10	frizzled homolog 10	0.030
hoxd4a	homeo box D4a	0.030
notch1b	notch homolog 1b	0.029
gata1a	GATA binding protein 1a	0.029
pcdh18b	protocadherin 18b	0.029
vox	ventral homeobox	0.029
hspb12	heat shock protein, alpha-crystallin-related, b12	0.028
tgfb2	transforming growth factor, beta 2	0.028
ndr1	nodal-related 1	0.028
spaw	southpaw	0.028
nppa	natriuretic peptide precursor A	0.028
hoxb1b	homeo box B1b	0.027
rbpms2	RNA binding protein with multiple splicing 2	0.027
foxa2	forkhead box A2	0.027
klf4	Kruppel-like factor 4	0.027
fbln1	fibulin 1	0.026
wu:fb01h12	wu:fb01h12	0.026
osr2	odd-skipped related 2 (Drosophila)	0.025
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.024
cd8a	CD8 antigen, alpha polypeptide	0.024
lef1	lymphocyte enhancer binding factor 1	0.024
klf2a	Kruppel-like factor 2a	0.024
gata6	GATA-binding protein 6	0.023
foxn4	forkhead box N4	0.023
gsna	gelsolin a	0.023
dbx1a	developing brain homeobox 1a	0.023
gata5	GATA-binding protein 5	0.022
six3a	sine oculis homeobox homolog 3a	0.021
msxc	muscle segment homeobox C	0.021
fgf17	fibroblast growth factor 17	0.021
tbx15	T-box 15	0.021	Zebrafish
nexn	nexilin (F actin binding protein)	0.020
pax9	paired box gene 9	0.020
wnt9a	wingless-type MMTV integration site family, member 9A	0.020
wu:fi04f09	wu:fi04f09	0.020
raraa	retinoic acid receptor, alpha a	0.020
hoxd11a	homeo box D11a	0.020
fzd8b	frizzled homolog 8b	0.020
il17rd	interleukin 17 receptor D	0.019
hapln1a	hyaluronan and proteoglycan link protein 1a	0.019
slc25a37	solute carrier family 25, member 37	0.019
bmper	BMP binding endothelial regulator	0.019
sox10	SRY-box containing gene 10	0.018
hhex	hematopoietically expressed homeobox	0.018
hoxa13a	homeo box A13a	0.018
vsx1	visual system homeobox 1 homolog, chx10-like	0.018
jag2	jagged 2	0.018
wnt8a	wingless-type MMTV integration site family, member 8a	0.018
foxd5	forkhead box D5	0.017
dcc	deleted in colorectal carcinoma	0.017
cdh5	cadherin 5	0.017
pitx2	paired-like homeodomain transcription factor 2	0.017
hoxd12a	homeo box D12a	0.017
hoxa11a	homeo box A11a	0.016
rarab	retinoic acid receptor, alpha b	0.016
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.015
osr1	odd-skipped related 1 (Drosophila)	0.015
hoxc8a	homeo box C8a	0.015
hoxa13b	homeo box A13b	0.015
prrx1b	paired related homeobox 1b	0.015
lhx1b	LIM homeobox 1b	0.015
foxd3	forkhead box D3	0.014
mespa	mesoderm posterior a	0.014
kita	kit receptor a	0.014
oprd1b	opioid receptor, delta 1b	0.014
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.014
bmp10	bone morphogenetic protein 10	0.014
nkx2.3	NK2 transcription factor related 3	0.014
meis3	myeloid ecotropic viral integration site 3	0.013
lmo4a	LIM domain only 4a	0.013
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.013
nkx3.2	NK3 homeobox 2	0.013
igf1rb	insulin-like growth factor 1b receptor	0.013
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.013
blf	bloody fingers	0.013
dla	deltaA	0.012
mef2cb	myocyte enhancer factor 2cb	0.012
sp5l	Sp5 transcription factor-like	0.012
admp	anti-dorsalizing morphogenic protein	0.012
traf4a	tnf receptor-associated factor 4a	0.012
irx3a	iroquois homeobox protein 3a	0.012
bmpr2b	bone morphogenetic protein receptor, type II b (serine/threonine kinase)	0.012
bon	bonnie and clyde	0.012
erg	v-ets erythroblastosis virus E26 oncogene like (avian)	0.012
irx1a	iroquois homeobox protein 1, a	0.012
slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.011
lhx5	LIM homeobox 5	0.011
axin1	axin 1	0.011
rargb	retinoic acid receptor, gamma b	0.011
foxg1a	forkhead box G1a	0.011
hoxa10b	homeo box A10b	0.011
gro2	groucho 2	0.011
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.011
myf5	myogenic factor 5	0.011
vasa	vasa homolog	0.011
smad5	MAD homolog 5 (Drosophila)	0.011
dct	dopachrome tautomerase	0.011
cdh1	cadherin 1, epithelial	0.010
lfng	lunatic fringe homolog	0.010
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.010
evx1	even-skipped homeobox 1	0.010
lrrc6	leucine rich repeat containing 6	0.010
dlc	deltaC	0.010