IMP

Process View

Danio rerio

11 genes annotated in zebrafish

response to osmotic stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to osmotic stress"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to osmotic stress" (in gray)

Name	Description	Probability	Func Analog Organism
gria1a	glutamate receptor, ionotropic, AMPA 1a	0.983	Worm
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.879
slc26a3	solute carrier family 26, member 3	0.829
ca2	carbonic anhydrase II	0.829
gria4a	glutamate receptor, ionotropic, AMPA 4a	0.655	Worm
atp6v1al	ATPase, H+ transporting, lysosomal V1 subunit A, like	0.650
gria1b	glutamate receptor, ionotropic, AMPA 1b	0.533	Worm
gria3b	glutamate receptor, ionotrophic, AMPA 3b	0.521	Worm
gria2b	glutamate receptor, ionotropic, AMPA 2b	0.509	Worm
ca15a	carbonic anhydrase XV a	0.491	Zebrafish
gria4b	glutamate receptor, ionotropic, AMPA 4b	0.455	Worm
ift88	intraflagellar transport 88 homolog	0.431
slc9a3.2	solute carrier family 9 (sodium/hydrogen exchanger), member 3.2	0.395
gria3a	glutamate receptor, ionotropic, AMPA 3a	0.383	Worm
gria2a	glutamate receptor, ionotropic, AMPA 2a	0.349	Worm
chrm2a	cholinergic receptor, muscarinic 2a	0.259
slc26a4	solute carrier family 26, member 4	0.229
dab1b	disabled homolog 1b (Drosophila)	0.227
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.183
eno2	enolase 2	0.173
ntn2	netrin 2	0.107
slc12a10.2	solute carrier family 12 (sodium/potassium/chloride transporters), member 10.2	0.107
slc2a13	solute carrier family 2 (facilitated glucose transporter), member 13	0.098
mgp	matrix Gla protein	0.088
wnt10a	wingless-type MMTV integration site family, member 10a	0.083
trpv1	transient receptor potential cation channel subfamily V member 1	0.080
LOC100005108	novel protein similar to solute carrier family 26, member 5 (slc26a5)	0.079
epas1b	endothelial PAS domain protein 1b	0.078
pink1	PTEN induced putative kinase 1	0.077
slc17a6b	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b	0.066
rcor1	REST corepressor 1	0.063
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.062
LOC790901	glucose-dependent insulinotropic polypeptide	0.059
rhcgl1	Rhesus blood group, C glycoprotein, like 1	0.058
zgc:136878	zgc:136878	0.055
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.054
LOC560602	novel protein similar to vertebrate solute carrier family 2 (facilitated glucose transporter), member 6 (SLC2A6)	0.054
gc3	guanylyl cyclase 3	0.051
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.051
slc2a9l2	solute carrier family 2 (facilitated glucose transporter), member 9-like 2	0.049
zgc:171872	zgc:171872	0.048
rhag	Rhesus blood group-associated glycoprotein	0.046
si:ch211-284e13.2	si:ch211-284e13.2	0.046
pou3f2	POU class 3 homeobox 2	0.043
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.043
reln	reelin	0.042
slc2a12	solute carrier family 2 (facilitated glucose transporter), member 12	0.041
ccng1	cyclin G1	0.040
gper	G protein-coupled estrogen receptor 1	0.037
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.036
pthlh	parathyroid hormone-like hormone	0.036
kcnq3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.036
ift57	intraflagellar transport protein 57	0.033
ppp3r1a	protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, a	0.033
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.032
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.031
csad	cysteine sulfinic acid decarboxylase	0.030
zgc:101724	zgc:101724	0.030
si:ch73-9j13.1	si:ch73-9j13.1	0.029
nxph1	neurexophilin 1	0.029
camsap1l1	calmodulin regulated spectrin-associated protein 1-like 1	0.028
mef2d	myocyte enhancer factor 2d	0.028	Yeast
ef1a	elongation factor 1-alpha	0.028
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.028
nr0b1	nuclear receptor subfamily 0, group B, member 1	0.027
mapk1	mitogen-activated protein kinase 1	0.027
wu:fb80a07	wu:fb80a07	0.027
neurog3	neurogenin 3	0.026
vasp	vasodilator-stimulated phosphoprotein	0.026
stx1b	syntaxin 1B	0.026
ptn	pleiotrophin	0.025
npdc1	neural proliferation, differentiation and control, 1	0.025
casrl	calcium-sensing receptor, like	0.025
prox1	prospero-related homeobox gene 1	0.024
slc17a6a	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6a	0.024
uxs1	UDP-glucuronic acid decarboxylase 1	0.023
mkrn2	makorin, ring finger protein, 2	0.023
zgc:56010	zgc:56010	0.023
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.022
otpa	orthopedia homolog a	0.022
eif3s10	eukaryotic translation initiation factor 3, subunit 10 (theta)	0.021
zgc:101523	zgc:101523	0.021
zgc:56304	zgc:56304	0.021
hk1	hexokinase 1	0.021
ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.021
lhx2a	LIM homeobox 2a	0.021
rhcgb	Rhesus blood group, C glycoprotein b	0.021
rgs4	regulator of G-protein signalling 4	0.020
rtn4b	reticulon 4b	0.019
mapk7	mitogen-activated protein kinase 7	0.019
ghrl	ghrelin/obestatin preprohormone	0.019
a2ml	alpha-2-macroglobulin-like	0.019
dctn1a	dynactin 1a	0.019
cx35	connexin 35	0.019
cdk10	cyclin-dependent kinase 10	0.019
bag6	BCL2-associated athanogene 6	0.018
ilk	integrin linked kinase	0.018
panx1	pannexin 1	0.018
sema6dl	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like	0.018
ddc	dopa decarboxylase	0.018
slc2a11l	solute carrier family 2 (facilitated glucose transporter), member 11-like	0.017
lhx8a	LIM homeobox 8a	0.017
grb10a	growth factor receptor-bound protein 10a	0.017
psen1	presenilin 1	0.017
mkrn4	makorin, ring finger protein, 4	0.017
ybx1	Y box binding protein 1	0.017
mmp15a	matrix metallopeptidase 15a	0.017
mapk14b	mitogen-activated protein kinase 14b	0.017	Yeast Worm Fly
syt4	synaptotagmin IV	0.017
avpr1b	arginine vasopressin receptor 1B	0.016
dnaja1l	DnaJ (Hsp40) homolog, subfamily A, member 1, like	0.016
LOC569045	novel protein similar to vertebrate WD repeat domain 44 (WDR44)	0.016
s100b	S100 calcium binding protein, beta (neural)	0.016
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.016
myf6	myogenic factor 6	0.016
rtn3	reticulon 3	0.016
mkrn1	makorin, ring finger protein, 1	0.016
scn1lab	sodium channel, voltage-gated, type I like, alpha b	0.016	Mouse
zgc:112180	zgc:112180	0.015
zdhhc8b	zinc finger, DHHC-type containing 8b	0.015
pknox1.2	pbx/knotted 1 homeobox 1.2	0.015
gfra1a	gdnf family receptor alpha 1a	0.015
tp53	tumor protein p53	0.015	Mouse
ahsg	alpha-2-HS-glycoprotein	0.015
cnga5	cyclic nucleotide gated channel alpha 5	0.015
tsc1a	tuberous sclerosis 1a	0.014
LOC556841	novel protein similar to vertebrate potassium voltage-gated channel, KQT-like subfamily, member 5 (KCNQ5)	0.014
cldn15a	claudin 15a	0.014
mpp2b	membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2b)	0.014
cntn2	contactin 2	0.014
wu:fi25h02	wu:fi25h02	0.014
apobec2a	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a	0.014
mef2bnb	mef2b neighbor	0.013
si:dkey-76b14.4	si:dkey-76b14.4	0.013
cadm3	cell adhesion molecule 3	0.013
stra6	stimulated by retinoic acid gene 6 homolog (mouse)	0.013
paqr5a	progestin and adipoQ receptor family member Va	0.013
dlg2	discs, large (Drosophila) homolog 2	0.013
sema3ga	semaphorin 3ga	0.013
prmt8b	protein arginine methyltransferase 8b	0.013
LOC560358	solute carrier family 2, facilitated glucose transporter member 11-like	0.013
tardbpl	TAR DNA binding protein, like	0.013
flii	flightless I homolog (Drosophila)	0.013
tcp1	t-complex polypeptide 1	0.013
sfrp1b	secreted frizzled-related protein 1b	0.012
ptbp1a	polypyrimidine tract binding protein 1a	0.012
fbp1b	fructose-1,6-bisphosphatase 1b	0.012
pou3f3a	POU class 3 homeobox 3a	0.012
gnao1a	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a	0.012
LOC100329340	sodium-dependent phosphate transport protein 2A-like	0.012
dync1h1	dynein, cytoplasmic 1, heavy chain 1	0.012
srf	serum response factor	0.012
nras	neuroblastoma RAS viral (v-ras) oncogene homolog	0.012
scn1ba	sodium channel, voltage-gated, type I, beta a	0.012
atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.012
lama2	laminin, alpha 2	0.012
cacnb2a	calcium channel, voltage-dependent, beta 2a	0.012
LOC561889	granulito	0.012
trpm6	transient receptor potential cation channel, subfamily M, member 6	0.012
ttc26	tetratricopeptide repeat domain 26	0.012
prkci	protein kinase C, iota	0.011
mmp17b	matrix metallopeptidase 17b	0.011
il1rapl1b	interleukin 1 receptor accessory protein-like 1b	0.011
maptb	microtubule-associated protein tau b	0.011
igfbp1b	insulin-like growth factor binding protein 1b	0.011
sepp1a	selenoprotein P, plasma, 1a	0.011
mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.011
csnk1db	casein kinase 1, delta b	0.011
henmt1	HEN1 methyltransferase homolog 1 (Arabidopsis)	0.011
jhdm1da	jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)	0.011
tlr21	toll-like receptor 21	0.011
apaf1	apoptotic protease activating factor 1	0.011
adrb2b	adrenergic receptor, beta 2b	0.011
LOC569768	metabotropic glutamate receptor 8-like	0.011
gphn2	gephyrin2	0.011
enc1	ectodermal-neural cortex (with BTB-like domain)	0.011
exorh	extra-ocular rhodopsin	0.011
ca10a	carbonic anhydrase Xa	0.011
s1pr2	sphingosine-1-phosphate receptor 2	0.011
ap2b1	adaptor-related protein complex 2, beta 1 subunit	0.011
zgc:64114	zgc:64114	0.011
ednra	endothelin receptor type A	0.010
zgc:112329	zgc:112329	0.010
celf2	cugbp, Elav-like family member 2	0.010
s100a11	S100 calcium binding protein A11	0.010
ttc21b	tetratricopeptide repeat domain 21B	0.010
LOC795916	mucolipin-1-like	0.010
hsp70l	heat shock cognate 70-kd protein, like	0.010
sst1.1	somatostatin 1, tandem duplicate 1	0.010
lamb2	laminin, beta 2 (laminin S)	0.010
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.010
sec23b	Sec23 homolog B (S. cerevisiae)	0.010
ulk2	unc-51-like kinase 2 (C. elegans)	0.010
tal1	T-cell acute lymphocytic leukemia 1	0.010
tph1a	tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a	0.010