IMP

Process View

Danio rerio

1 genes annotated in zebrafish

glutamate receptor signaling pathway

A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glutamate receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glutamate receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
gria2b	glutamate receptor, ionotropic, AMPA 2b	0.960	Human Mouse Rat Worm
gria1a	glutamate receptor, ionotropic, AMPA 1a	0.948	Human Worm
gria4a	glutamate receptor, ionotropic, AMPA 4a	0.923	Human Rat Worm
gria3a	glutamate receptor, ionotropic, AMPA 3a	0.905	Worm
gria3b	glutamate receptor, ionotrophic, AMPA 3b	0.900	Worm
gria2a	glutamate receptor, ionotropic, AMPA 2a	0.881	Human Mouse Rat Worm
gria1b	glutamate receptor, ionotropic, AMPA 1b	0.851	Human Worm
nlgn2b	neuroligin 2b	0.793
nlgn2a	neuroligin 2a	0.756
gria4b	glutamate receptor, ionotropic, AMPA 4b	0.652	Rat Worm
nlgn4b	neuroligin 4b	0.505
uts1	urotensin 1	0.404
cyp19a1b	cytochrome P450, family 19, subfamily A, polypeptide 1b	0.354
nlgn3a	neuroligin 3a	0.347	Mouse
ndrg4	N-myc downstream regulated gene 4	0.226
cadm4	cell adhesion molecule 4	0.224
sncgb	synuclein, gamma b (breast cancer-specific protein 1)	0.224
grin1a	glutamate receptor, ionotropic, N-methyl D-aspartate 1a	0.220	Fly
dlg2	discs, large (Drosophila) homolog 2	0.211
oprk1	opioid receptor, kappa 1	0.194
mpz	myelin protein zero	0.189
gper	G protein-coupled estrogen receptor 1	0.185
nr4a2b	nuclear receptor subfamily 4, group A, member 2b	0.144
pvrl1b	poliovirus receptor-related 1b	0.135
aldocb	aldolase C, fructose-bisphosphate, b	0.129
nlgn4a	neuroligin 4a	0.108
LOC100007758	novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3)	0.092
aplp2	amyloid beta (A4) precursor-like protein 2	0.089
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.089
penka	proenkephalin a	0.086
oprd1a	opioid receptor, delta 1a	0.082
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.078
ppp3r1b	protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b	0.071
LOC555504	novel protocadherin protein	0.070
sc:d0319	sc:d0319	0.068
gnao1a	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a	0.067
calb2a	calbindin 2a	0.067
s1pr2	sphingosine-1-phosphate receptor 2	0.066
cnr1	cannabinoid receptor 1	0.065
eno1	enolase 1, (alpha)	0.064
si:ch211-191i18.3	si:ch211-191i18.3	0.062
wu:fj39b01	wu:fj39b01	0.059
pygmb	phosphorylase, glycogen (muscle) b	0.058
pcdh7	protocadherin 7	0.056
il1rapl1b	interleukin 1 receptor accessory protein-like 1b	0.054
eno2	enolase 2	0.052
nxph1	neurexophilin 1	0.052
grin1b	glutamate receptor, ionotropic, N-methyl D-aspartate 1b	0.051	Fly
oprd1b	opioid receptor, delta 1b	0.049
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.048
mef2ca	myocyte enhancer factor 2ca	0.047	Mouse
cadm2a	cell adhesion molecule 2a	0.046
nr4a3	nuclear receptor subfamily 4, group A, member 3	0.046
gnrh3	gonadotropin-releasing hormone 3	0.044
adarb1	adenosine deaminase, RNA-specific, B1	0.043
sncb	synuclein, beta	0.042
robo2	roundabout homolog 2	0.041
fbxo7	F-box protein 7	0.040
dab1a	disabled homolog 1a (Drosophila)	0.040
wu:fi18a01	wu:fi18a01	0.040
lepr	leptin receptor	0.039
plxnb2b	plexin b2b	0.036
nr4a2a	nuclear receptor subfamily 4, group A, member 2a	0.035
snrk1	SNF related kinase 1	0.035
nelfb	nasal embryonic LHRH factor b	0.035
slc17a6b	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b	0.035
robo1	roundabout homolog 1	0.034
selp	selectin P	0.031
gfra1b	gdnf family receptor alpha 1b	0.031
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.030
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.030
usp2a	ubiquitin specific peptidase 2a	0.029
gad2	glutamate decarboxylase 2	0.028
LOC569768	metabotropic glutamate receptor 8-like	0.027
hk1	hexokinase 1	0.027
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.027
mmp15a	matrix metallopeptidase 15a	0.027
nlgn3b	neuroligin 3b	0.026	Mouse
kcnq3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.026
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.026
ppp3cb	protein phosphatase 3, catalytic subunit, beta isozyme	0.026
crhbp	corticotropin releasing hormone binding protein	0.025
atp1a2a	ATPase, Na+/K+ transporting, alpha 2a polypeptide	0.025
ppp3r1a	protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, a	0.025
spon1b	spondin 1b	0.025
spock3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	0.025
mef2a	myocyte enhancer factor 2a	0.024
tac1	tachykinin 1	0.024
cadm2b	cell adhesion molecule 2b	0.024
dcc	deleted in colorectal carcinoma	0.024
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.023
atp1a1b	ATPase, Na+/K+ transporting, alpha 1b polypeptide	0.023
gfap	glial fibrillary acidic protein	0.022
dlg4	discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)	0.022	Rat
mef2cb	myocyte enhancer factor 2cb	0.022	Mouse
zgc:73155	zgc:73155	0.022
glra4b	glycine receptor, alpha 4b	0.021
tcf12	transcription factor 12	0.021
cadm1a	cell adhesion molecule 1a	0.021
mapk8b	mitogen-activated protein kinase 8b	0.021
cdh10	cadherin 10, type 2 (T2-cadherin)	0.021
kal1a	Kallmann syndrome 1a sequence	0.021
lox	lysyl oxidase	0.020
grm1a	glutamate receptor, metabotropic 1a	0.020
dpysl4	dihydropyrimidinase-like 4	0.020
stau1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.020
cyfip2	cytoplasmic FMR1 interacting protein 2	0.020
LOC799274	kinesin heavy chain isoform 5A-like	0.020
appa	amyloid beta (A4) precursor protein a	0.020	Mouse
copeb	core promoter element binding protein	0.019
limk2	LIM domain kinase 2	0.019
zgc:55418	zgc:55418	0.019
gnrh2	gonadotropin-releasing hormone 2	0.019
flrt1b	fibronectin leucine rich transmembrane 1b	0.019
atp6v0cb	ATPase, H+ transporting, lysosomal, V0 subunit c, b	0.019
dmbx1b	diencephalon/mesencephalon homeobox 1b	0.019
st8sia5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	0.018
adcyap1r1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	0.018
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.018
scrt1a	scratch homolog 1, zinc finger protein a (Drosophila)	0.018
spon2b	spondin 2b, extracellular matrix protein	0.018
foxo3a	forkhead box O3A	0.018
LOC568484	glutamate receptor, metabotropic	0.018
ctrl	chymotrypsin-like	0.018
prom1a	prominin 1a	0.018
si:dkeyp-63d11.7	si:dkeyp-63d11.7	0.017
gad1b	glutamate decarboxylase 1b	0.017
spna2	spectrin alpha 2	0.017
stac3	SH3 and cysteine rich domain 3	0.017
LOC100334210	growth/differentiation factor 5-like	0.017
cadm1b	cell adhesion molecule 1b	0.016
gap43	growth associated protein 43	0.016
prmt8b	protein arginine methyltransferase 8b	0.016
prkcz	protein kinase C, zeta	0.016
plxna3	plexin A3	0.016
LOC559201	similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3)	0.016
tmem2	transmembrane protein 2	0.016
tp53inp1	tumor protein p53 inducible nuclear protein 1	0.016
scrt1b	scratch homolog 1, zinc finger protein b (Drosophila)	0.016
cx36.7	connexin 36.7	0.016
mmrn2a	multimerin 2a	0.016
pgk1	phosphoglycerate kinase 1	0.015
mmp17a	matrix metallopeptidase 17a	0.015
foxp2	forkhead box P2	0.015
LOC569642	hypothetical protein LOC569642	0.015
rpe65b	retinal pigment epithelium-specific protein 65b	0.015
prkar1aa	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a	0.015
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.014
zgc:152997	zgc:152997	0.014
vmhc	ventricular myosin heavy chain	0.014
clstn1	calsyntenin 1	0.014
pkm2a	pyruvate kinase, muscle, a	0.014
barhl1.2	BarH-like 1.2	0.014
nr1d2a	nuclear receptor subfamily 1, group D, member 2a	0.014
etv1	ets variant gene 1	0.014
nlgn1	neuroligin 1	0.013
wu:fj52c07	wu:fj52c07	0.013
dlg1	discs, large (Drosophila) homolog 1	0.013
tpi1b	triosephosphate isomerase 1b	0.013
zgc:77714	zgc:77714	0.013
si:ch211-244a23.1	si:ch211-244a23.1	0.013
sult1st3	sulfotransferase family 1, cytosolic sulfotransferase 3	0.013
alk	anaplastic lymphoma kinase (Ki-1)	0.013
trpa1b	transient receptor potential cation channel, subfamily A, member 1b	0.013
nrxn2a	neurexin 2a	0.013
or111-7	odorant receptor, family D, subfamily 111, member 7	0.013
zgc:193504	zgc:193504	0.013
fkbp1b	FK506 binding protein 1b	0.013
avpr1b	arginine vasopressin receptor 1B	0.013
trim8	tripartite motif-containing 8	0.012
cntfr	ciliary neurotrophic factor receptor	0.012
csad	cysteine sulfinic acid decarboxylase	0.012
ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.012
cdh4	cadherin 4, retinal	0.012
stau2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.012
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.012
LOC560944	6-phosphofructokinase type C-like	0.012
necab1	N-terminal EF-hand calcium binding protein 1	0.012
atg12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.012
gsx1	GS homeobox 1	0.012
cftr	cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)	0.012
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.011
lamb2	laminin, beta 2 (laminin S)	0.011
LOC100535061	meiosis inhibitor protein 1-like	0.011
cacna1da	calcium channel, voltage-dependent, L type, alpha 1D subunit, a	0.011
timp2a	tissue inhibitor of metalloproteinase 2a	0.011
slc17a6a	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6a	0.011
spg11	spastic paraplegia 11	0.011
mbnl2	muscleblind-like 2 (Drosophila)	0.011
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.011
edn1	endothelin 1	0.011
casrl	calcium-sensing receptor, like	0.011
cdh23	cadherin-like 23	0.011
serinc1	serine incorporator 1	0.011
il1rapl2	interleukin 1 receptor accessory protein-like 2	0.011
mc4r	melanocortin 4 receptor	0.011
wnt5a	wingless-type MMTV integration site family, member 5a	0.011
chat	choline acetyltransferase	0.011
slitrk4	slit and trk like 4 protein	0.011
fstl4	follistatin-like 4	0.011
trpc5	transient receptor potential cation channel, subfamily C, member 5	0.011
slc10a2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.010
hrh1	histamine receptor H1	0.010
zgc:77409	zgc:77409	0.010
ptpra	protein tyrosine phosphatase, receptor type, A	0.010
nptx2a	neuronal pentraxin 2a	0.010
maff	v-maf musculoaponeurotic fibrosarcoma oncogene homolog f (avian)	0.010
birc2	baculoviral IAP repeat-containing 2	0.010
odz4	odd Oz/ten-m homolog 4	0.010
si:dkey-25o1.2	si:dkey-25o1.2	0.010
s100b	S100 calcium binding protein, beta (neural)	0.010
tnnc1a	troponin C type 1a (slow)	0.010
emx2	empty spiracles homeobox 2	0.010
trpv1	transient receptor potential cation channel subfamily V member 1	0.010