Process View
The network for 'positive regulation of interleukin 8 biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| C9orf89 | chromosome 9 open reading frame 89 | 0.976 | |
| CARD11 | caspase recruitment domain family, member 11 | 0.956 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.907 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.897 | |
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.895 | |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.828 | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.622 | |
| LY96 | lymphocyte antigen 96 | 0.548 | |
| TRAF2 | TNF receptor-associated factor 2 | 0.460 | |
| ALB | albumin | 0.457 | |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.277 | |
| MPO | myeloperoxidase | 0.206 | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.202 | |
| TLR4 | toll-like receptor 4 | 0.186 | |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.141 | |
| TRADD | TNFRSF1A-associated via death domain | 0.124 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.115 | |
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.115 | |
| TLR2 | toll-like receptor 2 | 0.102 | |
| AZU1 | azurocidin 1 | 0.077 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.076 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.068 | |
| CTSG | cathepsin G | 0.058 | |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.044 | |
| PRTN3 | proteinase 3 | 0.040 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.039 | |
| ELANE | elastase, neutrophil expressed | 0.037 | |
| APOA1 | apolipoprotein A-I | 0.034 | |
| LY86 | lymphocyte antigen 86 | 0.032 | |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.030 | |
| BCL3 | B-cell CLL/lymphoma 3 | 0.029 | |
| VNN2 | vanin 2 | 0.028 | |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.026 | |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.025 | |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.023 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.022 | |
| BPI | bactericidal/permeability-increasing protein | 0.021 | |
| CAMP | cathelicidin antimicrobial peptide | 0.021 | |
| TLR6 | toll-like receptor 6 | 0.020 | |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.019 | |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.019 | |
| TFEC | transcription factor EC | 0.018 | |
| TLR1 | toll-like receptor 1 | 0.018 | |
| SQSTM1 | sequestosome 1 | 0.016 | |
| DEFA4 | defensin, alpha 4, corticostatin | 0.016 | |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 0.015 | |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.015 | |
| CYBB | cytochrome b-245, beta polypeptide | 0.015 | |
| EVI2A | ecotropic viral integration site 2A | 0.015 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.015 | |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.015 | |
| C3AR1 | complement component 3a receptor 1 | 0.013 | |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.013 | |
| CLEC4G | C-type lectin domain family 4, member G | 0.013 | |
| CD86 | CD86 molecule | 0.013 | |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.012 | |
| ASGR2 | asialoglycoprotein receptor 2 | 0.012 | |
| MMP8 | matrix metallopeptidase 8 (neutrophil collagenase) | 0.011 | |
| TRAF6 | TNF receptor-associated factor 6 | 0.011 | |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.011 | |
| AHSG | alpha-2-HS-glycoprotein | 0.011 | |
| S100A12 | S100 calcium binding protein A12 | 0.011 | |
| CTSS | cathepsin S | 0.011 | |
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.010 | |
| PGLYRP1 | peptidoglycan recognition protein 1 | 0.010 | |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.010 |