The network for 'positive regulation of interleukin 8 biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of interleukin 8 biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8.

Name Description Probability Func Analog Organism
C9orf89 chromosome 9 open reading frame 89 0.976
CARD11 caspase recruitment domain family, member 11 0.956
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.907
MYD88 myeloid differentiation primary response gene (88) 0.897
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.895
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.828
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.622
LY96 lymphocyte antigen 96 0.548
TRAF2 TNF receptor-associated factor 2 0.460
ALB albumin 0.457
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.277
MPO myeloperoxidase 0.206
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.202
TLR4 toll-like receptor 4 0.186
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.141
TRADD TNFRSF1A-associated via death domain 0.124
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.115
TICAM2 toll-like receptor adaptor molecule 2 0.115
TLR2 toll-like receptor 2 0.102
AZU1 azurocidin 1 0.077
TRAF1 TNF receptor-associated factor 1 0.076
IRAK2 interleukin-1 receptor-associated kinase 2 0.068
CTSG cathepsin G 0.058
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.044
PRTN3 proteinase 3 0.040
CCR1 chemokine (C-C motif) receptor 1 0.039
ELANE elastase, neutrophil expressed 0.037
APOA1 apolipoprotein A-I 0.034
LY86 lymphocyte antigen 86 0.032
RNASE3 ribonuclease, RNase A family, 3 0.030
BCL3 B-cell CLL/lymphoma 3 0.029
VNN2 vanin 2 0.028
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.026
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.025
BTK Bruton agammaglobulinemia tyrosine kinase 0.023
BIRC3 baculoviral IAP repeat containing 3 0.022
BPI bactericidal/permeability-increasing protein 0.021
CAMP cathelicidin antimicrobial peptide 0.021
TLR6 toll-like receptor 6 0.020
IGSF6 immunoglobulin superfamily, member 6 0.019
RNASE6 ribonuclease, RNase A family, k6 0.019
TFEC transcription factor EC 0.018
TLR1 toll-like receptor 1 0.018
SQSTM1 sequestosome 1 0.016
DEFA4 defensin, alpha 4, corticostatin 0.016
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 0.015
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.015
CYBB cytochrome b-245, beta polypeptide 0.015
EVI2A ecotropic viral integration site 2A 0.015
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.015
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.015
C3AR1 complement component 3a receptor 1 0.013
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.013
CLEC4G C-type lectin domain family 4, member G 0.013
CD86 CD86 molecule 0.013
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.012
ASGR2 asialoglycoprotein receptor 2 0.012
MMP8 matrix metallopeptidase 8 (neutrophil collagenase) 0.011
TRAF6 TNF receptor-associated factor 6 0.011
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.011
AHSG alpha-2-HS-glycoprotein 0.011
S100A12 S100 calcium binding protein A12 0.011
CTSS cathepsin S 0.011
PDPK1 3-phosphoinositide dependent protein kinase-1 0.010
PGLYRP1 peptidoglycan recognition protein 1 0.010
FADD Fas (TNFRSF6)-associated via death domain 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism