The network for 'regulation of ventricular cardiac muscle cell membrane depolarization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of ventricular cardiac muscle cell membrane depolarization

Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.

Name Description Probability Func Analog Organism
Scn5a sodium channel, voltage-gated, type V, alpha 1.000
Tbx5 T-box 5 0.997
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.971
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.919
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.906
Tjp1 tight junction protein 1 0.835
Ryr2 ryanodine receptor 2, cardiac 0.751
Tbx3 T-box 3 0.681
Gjb6 gap junction protein, beta 6 0.542
Slurp1 secreted Ly6/Plaur domain containing 1 0.495
Pcdh12 protocadherin 12 0.453
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.410
Gjb2 gap junction protein, beta 2 0.359
Zfpm2 zinc finger protein, multitype 2 0.324
Ltbp1 latent transforming growth factor beta binding protein 1 0.255
Fgf8 fibroblast growth factor 8 0.247
Tgfb2 transforming growth factor, beta 2 0.245
Col13a1 collagen, type XIII, alpha 1 0.245
Kel Kell blood group 0.207
Fut2 fucosyltransferase 2 0.204
Kcne1l potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene 0.174
Nos3 nitric oxide synthase 3, endothelial cell 0.173
Gjb5 gap junction protein, beta 5 0.168
Rhox6 reproductive homeobox 6 0.168
Csda cold shock domain protein A 0.166
Lmna lamin A 0.156
Aplnr apelin receptor 0.155
Oprd1 opioid receptor, delta 1 0.151
Rcvrn recoverin 0.141
Fut1 fucosyltransferase 1 0.132
F12 coagulation factor XII (Hageman factor) 0.126
Pitx2 paired-like homeodomain transcription factor 2 0.113
Rem1 rad and gem related GTP binding protein 1 0.111
Bmp8b bone morphogenetic protein 8b 0.109
Scarb2 scavenger receptor class B, member 2 0.100
Gpc3 glypican 3 0.096
Krt31 keratin 31 0.094
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.089
H2-M9 histocompatibility 2, M region locus 9 0.086
Pla2g4f phospholipase A2, group IVF 0.086
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.085
Ntf3 neurotrophin 3 0.085
Fstl3 follistatin-like 3 0.085
Cldn19 claudin 19 0.082
Slc26a4 solute carrier family 26, member 4 0.082
Prph2 peripherin 2 0.081
Bfsp1 beaded filament structural protein 1, in lens-CP94 0.080
Hopx HOP homeobox 0.078
Hand2 heart and neural crest derivatives expressed transcript 2 0.077
Gli1 GLI-Kruppel family member GLI1 0.076
Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 0.076
Tcf15 transcription factor 15 0.074
Col17a1 collagen, type XVII, alpha 1 0.074
Wnt7a wingless-related MMTV integration site 7A 0.071
Jag1 jagged 1 0.069
Msx2 homeobox, msh-like 2 0.068
Hprt hypoxanthine guanine phosphoribosyl transferase 0.068
Insm2 insulinoma-associated 2 0.068
Defa-rs12 defensin, alpha, related sequence 12 0.066
Scn1a sodium channel, voltage-gated, type I, alpha 0.066
Cldn5 claudin 5 0.066
Podxl podocalyxin-like 0.065
Scn10a sodium channel, voltage-gated, type X, alpha 0.064
Krt36 keratin 36 0.064
Dsc1 desmocollin 1 0.063
Tcfap2c transcription factor AP-2, gamma 0.063
Sstr3 somatostatin receptor 3 0.062
Klk6 kallikrein related-peptidase 6 0.060
Crygd crystallin, gamma D 0.059
Kcnk3 potassium channel, subfamily K, member 3 0.058
Cldn6 claudin 6 0.056
Itih3 inter-alpha trypsin inhibitor, heavy chain 3 0.056
Sox7 SRY-box containing gene 7 0.055
Npas1 neuronal PAS domain protein 1 0.055
Krt15 keratin 15 0.054
Upk3b uroplakin 3B 0.054
Pax6 paired box gene 6 0.053
Nppc natriuretic peptide type C 0.053
A4galt alpha 1,4-galactosyltransferase 0.053
Slc16a8 solute carrier family 16 (monocarboxylic acid transporters), member 8 0.053
Sall4 sal-like 4 (Drosophila) 0.052
Itih1 inter-alpha trypsin inhibitor, heavy chain 1 0.051
Ly6g6d lymphocyte antigen 6 complex, locus G6D 0.050
Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 0.050
Ern2 endoplasmic reticulum (ER) to nucleus signalling 2 0.050
Gpr182 G protein-coupled receptor 182 0.050
Sult4a1 sulfotransferase family 4A, member 1 0.050
Atoh7 atonal homolog 7 (Drosophila) 0.049
Lrp2 low density lipoprotein receptor-related protein 2 0.049
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.049
Clic3 chloride intracellular channel 3 0.049
Foxc2 forkhead box C2 0.048
Nkx3-2 NK3 homeobox 2 0.048
Sstr1 somatostatin receptor 1 0.047
Uncx UNC homeobox 0.047
Grk1 G protein-coupled receptor kinase 1 0.046
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.046
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.046
Gja5 gap junction protein, alpha 5 0.045
Tmem40 transmembrane protein 40 0.045
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
TJP1 tight junction protein 1 (zona occludens 1) 0.240
SNTG2 syntrophin, gamma 2 0.045
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.015
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism