The network for 'neurotransmitter secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neurotransmitter secretion

The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.

Mus musculus
Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 1.000
Dlg4 discs, large homolog 4 (Drosophila) 0.997
Stx1a syntaxin 1A (brain) 0.996
Ret ret proto-oncogene 0.938
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.936
Snap25 synaptosomal-associated protein 25 0.923
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.916
Syp synaptophysin 0.899
Syt2 synaptotagmin II 0.853
Rab3a RAB3A, member RAS oncogene family 0.850
Drd2 dopamine receptor D2 0.844
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.840
Syt3 synaptotagmin III 0.784
Ina internexin neuronal intermediate filament protein, alpha 0.778
Dnm1 dynamin 1 0.775
Actb actin, beta 0.768
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.738
Arc activity regulated cytoskeletal-associated protein 0.728
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.716
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.702
Nrxn3 neurexin III 0.685
Pcsk2 proprotein convertase subtilisin/kexin type 2 0.632
Cbln1 cerebellin 1 precursor protein 0.628
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.619
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.583
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.570
Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 0.561
Myt1l myelin transcription factor 1-like 0.552
Rims2 regulating synaptic membrane exocytosis 2 0.550
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.539
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.533
Npas1 neuronal PAS domain protein 1 0.475
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.459
Scn8a sodium channel, voltage-gated, type VIII, alpha 0.455
Nos1 nitric oxide synthase 1, neuronal 0.450
Snap23 synaptosomal-associated protein 23 0.450
Chrd chordin 0.448
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.447
Vangl1 vang-like 1 (van gogh, Drosophila) 0.442
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.434
Vim vimentin 0.427
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.427
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.418
Necab2 N-terminal EF-hand calcium binding protein 2 0.414
Bsn bassoon 0.408
Srcin1 SRC kinase signaling inhibitor 1 0.406
Stxbp3a syntaxin binding protein 3A 0.403
Chrna9 cholinergic receptor, nicotinic, alpha polypeptide 9 0.393
Homer1 homer homolog 1 (Drosophila) 0.387
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 0.374
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.372
Syt9 synaptotagmin IX 0.363
Rho rhodopsin 0.361
Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma 0.352
Neto1 neuropilin (NRP) and tolloid (TLL)-like 1 0.349
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.345
Pgr progesterone receptor 0.329
Plcd1 phospholipase C, delta 1 0.309
Dlg1 discs, large homolog 1 (Drosophila) 0.309
Vip vasoactive intestinal polypeptide 0.309
Braf Braf transforming gene 0.303
Stx4a syntaxin 4A (placental) 0.300
Wnt3a wingless-related MMTV integration site 3A 0.292
Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 0.291
Nrxn2 neurexin II 0.290
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.283
Rph3a rabphilin 3A 0.270
Hdac4 histone deacetylase 4 0.267
Lhx1 LIM homeobox protein 1 0.265
Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit 0.264
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.263
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) 0.263
Rims1 regulating synaptic membrane exocytosis 1 0.259
Epha5 Eph receptor A5 0.258
Shank2 SH3/ankyrin domain gene 2 0.258
Nrxn1 neurexin I 0.257
Ncam2 neural cell adhesion molecule 2 0.252
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.251
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.250
Grid1 glutamate receptor, ionotropic, delta 1 0.250
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.247
Gpr3 G-protein coupled receptor 3 0.245
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.243
Plcb1 phospholipase C, beta 1 0.241
Cplx1 complexin 1 0.240
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.236
Cltc clathrin, heavy polypeptide (Hc) 0.234
Src Rous sarcoma oncogene 0.234
Klc2 kinesin light chain 2 0.233
Cdk5r2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.232
Mmp24 matrix metallopeptidase 24 0.230
Cacna2d3 calcium channel, voltage-dependent, alpha2/delta subunit 3 0.228
Rps6ka3 ribosomal protein S6 kinase polypeptide 3 0.227
Stxbp1 syntaxin binding protein 1 0.226
Kif1a kinesin family member 1A 0.224
Crhr1 corticotropin releasing hormone receptor 1 0.222
Prkcc protein kinase C, gamma 0.219
Nsf N-ethylmaleimide sensitive fusion protein 0.218
Sorcs3 sortilin-related VPS10 domain containing receptor 3 0.216
Wnt4 wingless-related MMTV integration site 4 0.216
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.435
egl-30 Protein EGL-30 0.386
unc-9 Protein UNC-9 0.351
unc-13 Protein UNC-13 0.319
F32B5.7 Protein F32B5.7 0.306
gar-3 Protein GAR-3 0.276
rpm-1 Protein RPM-1 0.204
gar-2 Protein GAR-2 0.199
M01A8.2 Protein M01A8.2 0.190
F54G2.1 Protein F54G2.1 0.156
pdfr-1 Protein PDFR-1 0.136
dlk-1 Protein DLK-1 0.125
rpy-1 Protein RPY-1 0.123
ptp-1 Protein PTP-1 0.118
crm-1 Protein CRM-1 0.116
ida-1 Protein IDA-1 0.106
nrx-1 Protein NRX-1 0.104
trp-1 Protein TRP-1 0.100
egl-5 Protein EGL-5 0.087
inx-1 Protein INX-1 0.081
egl-15 Protein EGL-15 0.077
frm-3 Protein FRM-3 0.071
unc-54 Protein UNC-54 0.071
egl-27 Protein EGL-27 0.065
ist-1 Protein IST-1 0.065
unc-53 Protein UNC-53 0.063
twk-29 Protein TWK-29 0.062
obr-3 Protein OBR-3 0.062
itr-1 Protein ITR-1 0.062
slo-2 Protein SLO-2 0.060
CELE_T04H1.2 Protein T04H1.2 0.055
plc-1 Protein PLC-1 0.054
stim-1 Protein STIM-1 0.053
unc-79 Protein UNC-79 0.052
casy-1 Protein CASY-1 0.052
H11E01.3 Protein H11E01.3 0.051
cul-6 Protein CUL-6 0.050
rgs-6 Protein RGS-6 0.050
csnk-1 Protein CSNK-1 0.049
dbl-1 Protein DBL-1 0.049
svh-2 Protein SVH-2 0.047
unc-10 Protein UNC-10 0.047
gpb-1 Protein GPB-1 0.044
zip-12 Protein ZIP-12 0.044
F31F7.1 Protein F31F7.1 0.043
F28E10.1 Protein F28E10.1 0.042
sdc-2 Protein SDC-2 0.042
unc-36 Protein UNC-36 0.042
glb-33 Protein GLB-33 0.042
DH11.5 Protein DH11.5 0.041
unc-80 Protein UNC-80 0.041
CELE_F52E1.9 Protein F52E1.9 0.040
CELE_Y41E3.3 Protein Y41E3.3 0.040
sli-1 Protein SLI-1 0.040
grk-2 Protein GRK-2 0.039
CELE_K08D8.4 Protein K08D8.4 0.039
T04F8.2 Protein T04F8.2 0.038
F46G10.2 Protein F46G10.2 0.038
sbt-1 Protein SBT-1 0.037
F46C5.2 Protein F46C5.2 0.037
lin-10 Protein LIN-10 0.036
C26B9.1 Protein C26B9.1 0.036
jnk-1 Protein JNK-1 0.036
dop-5 Protein DOP-5 0.035
let-23 Protein LET-23 0.035
klp-11 Protein KLP-11 0.035
pkc-2 Protein PKC-2 0.035
nhr-14 Protein NHR-14 0.034
CELE_H12D21.9 Protein H12D21.9 0.034
aat-5 Protein AAT-5 0.033
F45E4.3 Protein F45E4.3 0.033
unc-47 Protein UNC-47 0.032
egl-3 Protein EGL-3 0.032
mlk-1 Protein MLK-1 0.032
vav-1 Protein VAV-1 0.032
CELE_M176.5 Protein M176.5 0.032
cpin-1 Protein CPIN-1 0.032
CELE_H04M03.12 Protein H04M03.12 0.032
snx-14 Protein SNX-14 0.032
cmd-1 Protein CMD-1 0.031
glr-4 Protein GLR-4 0.031
unc-11 Protein UNC-11 0.031
mod-1 Protein MOD-1 0.031
pde-1 Protein PDE-1 0.030
egl-23 Protein EGL-23 0.030
F22D3.2 Protein F22D3.2 0.029
unc-31 Protein UNC-31 0.029
K05F1.6 Protein K05F1.6 0.028
ver-3 Protein VER-3 0.028
cal-4 Protein CAL-4 0.028
cap-1 Protein CAP-1 0.028
H10E21.5 Protein H10E21.5 0.028
pitp-1 Protein PITP-1 0.028
tps-1 Protein TPS-1 0.027
snt-1 Protein SNT-1 0.027
rgs-2 Protein RGS-2 0.027
glr-5 Protein GLR-5 0.027
B0507.2 Protein B0507.2 0.026
madd-4 Protein MADD-4 0.026
unc-17 Protein UNC-17 0.026
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
mllt11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.579
nf1a neurofibromin 1a 0.481
snap25a synaptosome-associated protein 25a 0.427
cplx2l complexin 2, like 0.359
islr2 immunoglobulin superfamily containing leucine-rich repeat 2 0.332
gcm2 glial cells missing homolog 2 (Drosophila) 0.317
stmn1b stathmin 1b 0.294
LOC799612 prolactin 2 0.286
flot1b flotillin 1b 0.258
spock3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.252
slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 0.238
nf1b neurofibromin 1b 0.236
hmgb3a high-mobility group box 3a 0.232
rtn1b reticulon 1b 0.220
ndrg4 N-myc downstream regulated gene 4 0.216
calm1b calmodulin 1b 0.215
mtor mechanistic target of rapamycin (serine/threonine kinase) 0.195
nos2a nitric oxide synthase 2a, inducible 0.192
snx1 sorting nexin 1 0.188
mbp myelin basic protein 0.181
syt11a synaptotagmin XIa 0.164
rab5c RAB5C, member RAS oncogene family 0.163
pdzd7a PDZ domain containing 7a 0.159
rbfox1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.156
alp alkaline phosphatase 0.155
sncb synuclein, beta 0.149
pob partial optokinetic response b 0.142
mpp5a membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) 0.141
pdzd7b PDZ domain containing 7b 0.138
wnt9b wingless-type MMTV integration site family, member 9B 0.138
nes nestin 0.135
rab7 RAB7, member RAS oncogene family 0.134
amigo1 adhesion molecule with Ig-like domain 1 0.132
hspb7 heat shock protein family, alpha-crystallin-related, b7 0.131
scg3 secretogranin III 0.127
rc3 rabconnectin 3 0.124
gnb5b guanine nucleotide binding protein (G protein), beta 5b 0.124
slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.123
apoeb apolipoprotein Eb 0.122
diras1a DIRAS family, GTP-binding RAS-like 1a 0.119
pard3 par-3 partitioning defective 3 homolog (C. elegans) 0.118
prkcz protein kinase C, zeta 0.118
negr1 neuronal growth regulator 1 0.116
kcnc3b potassium voltage-gated channel, Shaw-related subfamily, member 3b 0.115
lhfpl3 lipoma HMGIC fusion partner-like 3 0.113
dharma dharma 0.112
cfl2l cofilin 2, like 0.110
hspa5 heat shock protein 5 0.110
LOC100535549 cytoplasmic polyadenylation element-binding protein 4-like 0.109
itm2ca integral membrane protein 2Ca 0.108
zgc:85889 zgc:85889 0.105
rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.105
zgc:112355 zgc:112355 0.104
tspan7b tetraspanin 7b 0.102
unc45b unc-45 homolog B (C. elegans) 0.102
htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a 0.102
hspb12 heat shock protein, alpha-crystallin-related, b12 0.100
grk7a G-protein-coupled receptor kinase 7a 0.100
spag1 sperm associated antigen 1 0.096
nmnat2 nicotinamide nucleotide adenylyltransferase 2 0.095
zgc:77849 zgc:77849 0.094
slc12a2 solute carrier family 12 (potassium/chloride transporters), member 2 0.094
gng3 guanine nucleotide binding protein (G protein), gamma 3 0.094
cnn2 calponin 2 0.092
mef2cb myocyte enhancer factor 2cb 0.091
nadl1.2 neural adhesion molecule L1.2 0.090
slc30a2 solute carrier family 30 (zinc transporter), member 2 0.090
grin1a glutamate receptor, ionotropic, N-methyl D-aspartate 1a 0.090
stx1b syntaxin 1B 0.089
vangl2 vang-like 2 (van gogh, Drosophila) 0.087
hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.086
si:dkey-273o13.1 si:dkey-273o13.1 0.085
fhla four and a half LIM domains a 0.084
pak2a p21 (CDKN1A)-activated kinase 2a 0.084
tuba1l tubulin, alpha 1, like 0.084
ntrk2a neurotrophic tyrosine kinase, receptor, type 2a 0.084
rtn1a reticulon 1a 0.082
trpc5 transient receptor potential cation channel, subfamily C, member 5 0.081
zgc:162420 zgc:162420 0.081
syne2a spectrin repeat containing, nuclear envelope 2a 0.081
slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.080
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.079
nkx2.5 NK2 transcription factor related 5 0.079
celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 0.078
npepps aminopeptidase puromycin sensitive 0.078
ap3m2 adaptor-related protein complex 3, mu 2 subunit 0.077
macf1 microtubule-actin crosslinking factor 1 0.077
rest RE1-silencing transcription factor 0.077
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.077
hspb11 heat shock protein, alpha-crystallin-related, b11 0.077
slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 0.076
prkcea protein kinase C, epsilon a 0.076
vamp1 vesicle-associated membrane protein 1 0.075
pth2r parathyroid hormone 2 receptor 0.074
sbf1 SET binding factor 1 0.074
flrt1a fibronectin leucine rich transmembrane 1a 0.073
sypl2a synaptophysin-like 2a 0.072
zgc:109987 zgc:109987 0.072
tm9sf2 transmembrane 9 superfamily member 2 0.071
oaz2b ornithine decarboxylase antizyme 2b 0.070
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
GluRIIA Glutamate receptor IIA 1.000
brp bruchpilot 0.949
hiw highwire 0.893
Syt1 Synaptotagmin 1 0.893
Snap25 Synapse protein 25 0.861
wit wishful thinking 0.846
KaiRIA CG18039 gene product from transcript CG18039-RA 0.845
Syx1A Syntaxin 1A 0.829
Frq2 Frequenin 2 0.823
unc-13 CG2999 gene product from transcript CG2999-RA 0.816
PP2A-B' CG7913 gene product from transcript CG7913-RK 0.778
CaMKII Calcium/calmodulin-dependent protein kinase II 0.718
gbb glass bottom boat 0.710
dys dysfusion 0.699
CkIIalpha Casein kinase II alpha subunit 0.675
unc-104 CG8566 gene product from transcript CG8566-RB 0.667
Syt4 Synaptotagmin 4 0.651
comt comatose 0.649
faf fat facets 0.605
Ank2 Ankyrin 2 0.554
Snap Soluble NSF attachment protein 0.546
Frq1 Frequenin 1 0.466
stj straightjacket 0.414
CG31146 CG31146 gene product from transcript CG31146-RD 0.410
scb scab 0.408
dlg1 discs large 1 0.397
endoA endophilin A 0.363
par-1 CG8201 gene product from transcript CG8201-RA 0.343
TBPH CG10327 gene product from transcript CG10327-RC 0.340
Csp Cysteine string protein 0.331
Nrx-1 Neurexin 1 0.320
Smg1 CG32743 gene product from transcript CG32743-RA 0.279
beta-Spec beta Spectrin 0.267
Vmat Vesicular monoamine transporter 0.253
lap like-AP180 0.248
rtGEF rho-type guanine exchange factor 0.248
sev sevenless 0.223
Nsf2 NEM-sensitive fusion protein 2 0.218
AdoR Adenosine receptor 0.207
VAChT CG32848 gene product from transcript CG32848-RA 0.195
slo slowpoke 0.188
Actbeta Activin-beta 0.185
Gad1 Glutamic acid decarboxylase 1 0.183
stnA stoned A 0.174
mth methuselah 0.173
Dap160 Dynamin associated protein 160 0.172
CG9339 CG9339 gene product from transcript CG9339-RG 0.166
Chc Clathrin heavy chain 0.154
Rab3 Rab-protein 3 0.142
fz2 frizzled 2 0.140
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.137
Khc-73 Kinesin-73 0.136
Shab Shaker cognate b 0.133
tkv thickveins 0.129
GluRIIB Glutamate receptor IIB 0.120
Adar Adenosine deaminase acting on RNA 0.119
mnb minibrain 0.117
pAbp polyA-binding protein 0.113
foxo forkhead box, sub-group O 0.112
neuroligin CG13772 gene product from transcript CG13772-RA 0.107
Atpalpha Na pump alpha subunit 0.106
VGlut Vesicular glutamate transporter 0.105
Abl Abl tyrosine kinase 0.098
skf skiff 0.094
jeb jelly belly 0.092
dnc dunce 0.090
Amph Amphiphysin 0.089
rl rolled 0.082
Imp IGF-II mRNA-binding protein 0.079
Pde8 Phosphodiesterase 8 0.078
Dab Disabled 0.075
n-syb n-synaptobrevin 0.069
TyrR Tyramine receptor 0.068
Oli Olig family 0.066
Rab11 Rab-protein 11 0.065
mtt mangetout 0.065
CG32635 CG32635 gene product from transcript CG32635-RA 0.064
Rya-r44F Ryanodine receptor 44F 0.062
jar jaguar 0.062
TER94 CG2331 gene product from transcript CG2331-RA 0.060
CDase Ceramidase 0.058
Caki Calcium/calmodulin-dependent protein kinase 0.055
gammaSnap gamma-soluble NSF attachment protein 0.054
Pgk Phosphoglycerate kinase 0.052
wun wunen 0.051
nwk nervous wreck 0.051
CG15658 CG15658 gene product from transcript CG15658-RA 0.050
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.050
shi shibire 0.048
stmA stambha A 0.046
mle maleless 0.045
Calx Na/Ca-exchange protein 0.045
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.045
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.045
spict spichthyin 0.044
Vha100-1 CG1709 gene product from transcript CG1709-RF 0.043
bves CG32513 gene product from transcript CG32513-RA 0.042
Eaat1 Excitatory amino acid transporter 1 0.042
CG12753 CG12753 gene product from transcript CG12753-RB 0.042
GABA-B-R3 metabotropic GABA-B receptor subtype 3 0.042
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SNAP25 synaptosomal-associated protein, 25kDa 0.999
LRRK2 leucine-rich repeat kinase 2 0.999
MAPT microtubule-associated protein tau 0.993
DLG4 discs, large homolog 4 (Drosophila) 0.991
KCNJ4 potassium inwardly-rectifying channel, subfamily J, member 4 0.984
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.982
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.978
DRD2 dopamine receptor D2 0.973
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.970
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.960
NSF N-ethylmaleimide-sensitive factor 0.943
ARHGAP1 Rho GTPase activating protein 1 0.931
BAG1 BCL2-associated athanogene 0.930
STX5 syntaxin 5 0.911
VAMP3 vesicle-associated membrane protein 3 (cellubrevin) 0.872
STX1A syntaxin 1A (brain) 0.855
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.852
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.843
GSK3B glycogen synthase kinase 3 beta 0.834
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.825
PRKCA protein kinase C, alpha 0.792
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.790
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.783
DNM1 dynamin 1 0.728
DDX17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.724
APP amyloid beta (A4) precursor protein 0.698
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.650
SYN2 synapsin II 0.649
BSN bassoon (presynaptic cytomatrix protein) 0.645
KIF5B kinesin family member 5B 0.633
RHOA ras homolog gene family, member A 0.620
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.612
VIM vimentin 0.591
FADS2 fatty acid desaturase 2 0.558
RGS2 regulator of G-protein signaling 2, 24kDa 0.545
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.543
CLTC clathrin, heavy chain (Hc) 0.534
DHCR7 7-dehydrocholesterol reductase 0.524
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.486
MED31 mediator complex subunit 31 0.444
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.427
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.413
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.412
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.393
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 0.368
LRP6 low density lipoprotein receptor-related protein 6 0.361
ARRB1 arrestin, beta 1 0.361
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.359
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.351
HSPA1A heat shock 70kDa protein 1A 0.350
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.338
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.333
AP1M1 adaptor-related protein complex 1, mu 1 subunit 0.331
RAB3A RAB3A, member RAS oncogene family 0.324
RAB21 RAB21, member RAS oncogene family 0.319
EEA1 early endosome antigen 1 0.318
SDC2 syndecan 2 0.316
MAP2K6 mitogen-activated protein kinase kinase 6 0.314
MAP1B microtubule-associated protein 1B 0.307
STX4 syntaxin 4 0.305
ZNF746 zinc finger protein 746 0.301
SYT1 synaptotagmin I 0.292
PICALM phosphatidylinositol binding clathrin assembly protein 0.285
PRKCE protein kinase C, epsilon 0.285
ITSN1 intersectin 1 (SH3 domain protein) 0.278
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.277
CABP1 calcium binding protein 1 0.275
NECAB2 N-terminal EF-hand calcium binding protein 2 0.273
NTF4 neurotrophin 4 0.273
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.264
HSPA1B heat shock 70kDa protein 1B 0.260
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.257
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.253
STX11 syntaxin 11 0.252
DVL2 dishevelled, dsh homolog 2 (Drosophila) 0.245
NOG noggin 0.244
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.243
AMPH amphiphysin 0.242
MYST2 MYST histone acetyltransferase 2 0.239
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.230
OCRL oculocerebrorenal syndrome of Lowe 0.228
KCNQ2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.227
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.217
BAG3 BCL2-associated athanogene 3 0.217
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.214
KCNC1 potassium voltage-gated channel, Shaw-related subfamily, member 1 0.214
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.207
SNAP23 synaptosomal-associated protein, 23kDa 0.204
MAST1 microtubule associated serine/threonine kinase 1 0.202
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.200
BMI1 BMI1 polycomb ring finger oncogene 0.198
F11R F11 receptor 0.195
CLTCL1 clathrin, heavy chain-like 1 0.190
KSR1 kinase suppressor of ras 1 0.188
LPHN1 latrophilin 1 0.183
ARRB2 arrestin, beta 2 0.183
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.182
MATR3 matrin 3 0.181
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.181
PCNP PEST proteolytic signal containing nuclear protein 0.181
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Rattus norvegicus
Name Description Probability Func Analog Organism
Syn1 synapsin I 0.896
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.806
Apba2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.741
Rims1 regulating synaptic membrane exocytosis 1 0.707
Hpcal4 hippocalcin-like 4 0.606
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.345
Dlg4 discs, large homolog 4 (Drosophila) 0.331
Hsph1 heat shock 105/110 protein 1 0.322
Vamp2 vesicle-associated membrane protein 2 0.321
Gnao1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.320
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.295
Stx1a syntaxin 1A (brain) 0.279
Gria1 glutamate receptor, ionotropic, AMPA 1 0.276
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.257
Unc5a unc-5 homolog A (C. elegans) 0.257
Cplx1 complexin 1 0.239
B3gat1 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) 0.237
Sh3gl2 SH3-domain GRB2-like 2 0.236
Syt4 synaptotagmin IV 0.225
Myt1l myelin transcription factor 1-like 0.213
Neurod2 neurogenic differentiation 2 0.207
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.201
Amph amphiphysin 0.190
Syt1 synaptotagmin I 0.179
Syt7 synaptotagmin VII 0.170
Scn8a sodium channel, voltage gated, type VIII, alpha subunit 0.169
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.167
Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.163
Accn1 amiloride-sensitive cation channel 1, neuronal 0.162
Nlgn3 neuroligin 3 0.152
Stxbp1 syntaxin binding protein 1 0.152
Grm5 glutamate receptor, metabotropic 5 0.151
Syn2 synapsin II 0.145
Camk1g calcium/calmodulin-dependent protein kinase IG 0.139
Oprd1 opioid receptor, delta 1 0.132
Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.112
Epha5 EphA5 0.109
Pde1b phosphodiesterase 1B, calmodulin-dependent 0.107
Gnaz guanine nucleotide binding protein (G protein), alpha z polypeptide 0.106
Gad2 glutamate decarboxylase 2 0.103
Nrxn1 neurexin 1 0.102
Tacr3 tachykinin receptor 3 0.102
Syt11 synaptotagmin XI 0.098
Dio2 deiodinase, iodothyronine, type II 0.098
Mapk10 mitogen activated protein kinase 10 0.095
Camk2n2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.095
Grip1 glutamate receptor interacting protein 1 0.095
Dlg3 discs, large homolog 3 (Drosophila) 0.093
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.092
App amyloid beta (A4) precursor protein 0.090
Vsnl1 visinin-like 1 0.088
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.088
Pou3f2 POU class 3 homeobox 2 0.087
Dpp6 dipeptidylpeptidase 6 0.087
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.087
Sncb synuclein, beta 0.083
Atp6v1b2 ATPase, H transporting, lysosomal V1 subunit B2 0.082
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.081
Ina internexin neuronal intermediate filament protein, alpha 0.081
Map6 microtubule-associated protein 6 0.080
Hk1 hexokinase 1 0.079
Adap1 ArfGAP with dual PH domains 1 0.079
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.078
Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) 0.075
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.075
Nxph1 neurexophilin 1 0.072
Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.072
Grm2 glutamate receptor, metabotropic 2 0.072
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.070
Zfp382 zinc finger protein 382 0.068
Tnr tenascin R 0.068
Pcsk2 proprotein convertase subtilisin/kexin type 2 0.067
Chrm3 cholinergic receptor, muscarinic 3 0.067
Gabrd gamma-aminobutyric acid (GABA) A receptor, delta 0.067
Nrxn3 neurexin 3 0.065
RGD1562618 similar to RIKEN cDNA 6030419C18 gene 0.065
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.065
Calb2 calbindin 2 0.065
Rab3a RAB3A, member RAS oncogene family 0.064
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.064
Scn2b sodium channel, voltage-gated, type II, beta 0.063
Snap25 synaptosomal-associated protein 25 0.063
Cntnap1 contactin associated protein 1 0.063
Mcf2l MCF.2 cell line derived transforming sequence-like 0.062
Faim2 Fas apoptotic inhibitory molecule 2 0.061
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.060
Sstr3 somatostatin receptor 3 0.059
Nrxn2 neurexin 2 0.058
Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.057
Syp synaptophysin 0.056
Glp1r glucagon-like peptide 1 receptor 0.055
Grm7 glutamate receptor, metabotropic 7 0.054
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.054
Vamp1 vesicle-associated membrane protein 1 0.053
Bsn bassoon 0.052
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.051
Drd2 dopamine receptor D2 0.051
Lphn3 latrophilin 3 0.051
Dgkg diacylglycerol kinase, gamma 0.050
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.049
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism