The network for 'positive regulation of interleukin 8 secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of interleukin 8 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.

Name Description Probability Func Analog Organism
Wnt3a wingless-related MMTV integration site 3A 0.996
Lhx1 LIM homeobox protein 1 0.993
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.964
T brachyury 0.950
Casp1 caspase 1 0.877
Wnt4 wingless-related MMTV integration site 4 0.840
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.751
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.717
Aim2 absent in melanoma 2 0.693
Gdnf glial cell line derived neurotrophic factor 0.693
Pax8 paired box gene 8 0.672
Fzd8 frizzled homolog 8 (Drosophila) 0.605
Fgf8 fibroblast growth factor 8 0.583
Gbp5 guanylate binding protein 5 0.573
Fgf18 fibroblast growth factor 18 0.522
Wnt10b wingless related MMTV integration site 10b 0.486
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.444
Fzd10 frizzled homolog 10 (Drosophila) 0.431
Hoxa2 homeobox A2 0.427
Col13a1 collagen, type XIII, alpha 1 0.405
Wnt1 wingless-related MMTV integration site 1 0.393
Trp73 transformation related protein 73 0.366
Kl klotho 0.365
Slc34a2 solute carrier family 34 (sodium phosphate), member 2 0.356
Pax1 paired box gene 1 0.317
Clic3 chloride intracellular channel 3 0.315
Porcn porcupine homolog (Drosophila) 0.313
Hoxd11 homeobox D11 0.303
Pax2 paired box gene 2 0.299
Wnt2b wingless related MMTV integration site 2b 0.268
Sftpb surfactant associated protein B 0.259
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.259
Otx1 orthodenticle homolog 1 (Drosophila) 0.257
Lmx1b LIM homeobox transcription factor 1 beta 0.245
Wnt9a wingless-type MMTV integration site 9A 0.242
Efna4 ephrin A4 0.239
Pou3f3 POU domain, class 3, transcription factor 3 0.238
Pou3f1 POU domain, class 3, transcription factor 1 0.229
Wnt7a wingless-related MMTV integration site 7A 0.225
Nlrp3 NLR family, pyrin domain containing 3 0.205
Amhr2 anti-Mullerian hormone type 2 receptor 0.202
Ppl periplakin 0.198
Vax1 ventral anterior homeobox containing gene 1 0.189
Foxf1a forkhead box F1a 0.180
Wnt6 wingless-related MMTV integration site 6 0.177
Tbx2 T-box 2 0.175
Wnt11 wingless-related MMTV integration site 11 0.172
Bmp7 bone morphogenetic protein 7 0.165
Shh sonic hedgehog 0.162
Tnni2 troponin I, skeletal, fast 2 0.157
Dlx4 distal-less homeobox 4 0.153
Fgf15 fibroblast growth factor 15 0.148
Acan aggrecan 0.145
Sema3b sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.144
Amh anti-Mullerian hormone 0.142
Angpt4 angiopoietin 4 0.137
Emx2 empty spiracles homolog 2 (Drosophila) 0.135
Zfp771 zinc finger protein 771 0.135
Fzd1 frizzled homolog 1 (Drosophila) 0.134
Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 0.132
Scube1 signal peptide, CUB domain, EGF-like 1 0.124
Kcnh3 potassium voltage-gated channel, subfamily H (eag-related), member 3 0.123
Ihh Indian hedgehog 0.122
Foxf2 forkhead box F2 0.120
Phldb2 pleckstrin homology-like domain, family B, member 2 0.120
Gli2 GLI-Kruppel family member GLI2 0.120
Crlf1 cytokine receptor-like factor 1 0.118
Arx aristaless related homeobox 0.116
Nog noggin 0.113
2310002J15Rik RIKEN cDNA 2310002J15 gene 0.110
Itgb7 integrin beta 7 0.108
Myl7 myosin, light polypeptide 7, regulatory 0.106
Rarg retinoic acid receptor, gamma 0.106
Fzd6 frizzled homolog 6 (Drosophila) 0.105
Hoxa13 homeobox A13 0.105
Sfrp1 secreted frizzled-related protein 1 0.104
Tctex1d4 Tctex1 domain containing 4 0.102
Ptk7 PTK7 protein tyrosine kinase 7 0.101
Emx1 empty spiracles homolog 1 (Drosophila) 0.100
Lrp6 low density lipoprotein receptor-related protein 6 0.099
Irx4 Iroquois related homeobox 4 (Drosophila) 0.098
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.098
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.097
Ly6d lymphocyte antigen 6 complex, locus D 0.096
Hoxd9 homeobox D9 0.094
Zfp703 zinc finger protein 703 0.090
Twist2 twist homolog 2 (Drosophila) 0.089
2610109H07Rik RIKEN cDNA 2610109H07 gene 0.089
Gli3 GLI-Kruppel family member GLI3 0.088
Inhbb inhibin beta-B 0.087
Tacr1 tachykinin receptor 1 0.085
Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 0.085
Lmx1a LIM homeobox transcription factor 1 alpha 0.084
Lef1 lymphoid enhancer binding factor 1 0.080
Alx4 aristaless-like homeobox 4 0.080
Ephb2 Eph receptor B2 0.079
Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric 0.078
Rspo1 R-spondin homolog (Xenopus laevis) 0.078
Fgf3 fibroblast growth factor 3 0.077
Gli1 GLI-Kruppel family member GLI1 0.077
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
NLRC4 NLR family, CARD domain containing 4 0.380
MEFV Mediterranean fever 0.191
CD48 CD48 molecule 0.060
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.049
FGA fibrinogen alpha chain 0.048
CRP C-reactive protein, pentraxin-related 0.047
SH2D1A SH2 domain containing 1A 0.046
RIPK2 receptor-interacting serine-threonine kinase 2 0.039
FGB fibrinogen beta chain 0.038
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.029
PYDC2 pyrin domain containing 2 0.027
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.018
PDCD6IP programmed cell death 6 interacting protein 0.016
CAV1 caveolin 1, caveolae protein, 22kDa 0.015
PRKCQ protein kinase C, theta 0.013
CD2AP CD2-associated protein 0.012
CAV2 caveolin 2 0.012
FAS Fas (TNF receptor superfamily, member 6) 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism