IMP
Process View
The network for 'positive regulation of branching involved in ureteric bud morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of branching involved in ureteric bud morphogenesis
Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Pax2 | paired box gene 2 | 1.000 | |
| Fgf8 | fibroblast growth factor 8 | 1.000 | |
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
| Rarg | retinoic acid receptor, gamma | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Pax3 | paired box gene 3 | 1.000 | |
| Foxc2 | forkhead box C2 | 1.000 | |
| Foxc1 | forkhead box C1 | 0.999 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.999 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.999 | |
| Smo | smoothened homolog (Drosophila) | 0.999 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.999 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.999 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.998 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.997 | |
| Lhx1 | LIM homeobox protein 1 | 0.996 | |
| Fgf10 | fibroblast growth factor 10 | 0.996 | |
| Hoxa3 | homeobox A3 | 0.996 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.995 | |
| Pax8 | paired box gene 8 | 0.994 | |
| Pax6 | paired box gene 6 | 0.992 | |
| Sox2 | SRY-box containing gene 2 | 0.992 | |
| Sall4 | sal-like 4 (Drosophila) | 0.990 | |
| Msx1 | homeobox, msh-like 1 | 0.989 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.987 | |
| Nog | noggin | 0.984 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.978 | |
| Hoxa1 | homeobox A1 | 0.978 | |
| Wt1 | Wilms tumor 1 homolog | 0.978 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.974 | |
| Rarb | retinoic acid receptor, beta | 0.969 | |
| Msx2 | homeobox, msh-like 2 | 0.966 | |
| Tbx1 | T-box 1 | 0.965 | |
| Sox9 | SRY-box containing gene 9 | 0.965 | |
| Bmp4 | bone morphogenetic protein 4 | 0.964 | |
| Hoxb3 | homeobox B3 | 0.948 | |
| Hoxd3 | homeobox D3 | 0.937 | |
| Hoxd11 | homeobox D11 | 0.935 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.930 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.928 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.923 | |
| Prrx1 | paired related homeobox 1 | 0.918 | |
| Hoxc5 | homeobox C5 | 0.909 | |
| Bmp7 | bone morphogenetic protein 7 | 0.908 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.903 | |
| En1 | engrailed 1 | 0.890 | |
| Dlx5 | distal-less homeobox 5 | 0.889 | |
| Hoxa2 | homeobox A2 | 0.888 | |
| Hoxa10 | homeobox A10 | 0.887 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.886 | |
| Hoxa5 | homeobox A5 | 0.883 | |
| Rara | retinoic acid receptor, alpha | 0.877 | |
| Hoxd9 | homeobox D9 | 0.872 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.870 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.856 | |
| Hoxb6 | homeobox B6 | 0.848 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.848 | |
| Ret | ret proto-oncogene | 0.845 | |
| Fgf3 | fibroblast growth factor 3 | 0.842 | |
| Prrx2 | paired related homeobox 2 | 0.830 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.828 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.803 | |
| Hoxd4 | homeobox D4 | 0.796 | |
| Hoxa11 | homeobox A11 | 0.776 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.762 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.756 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.749 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.732 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.718 | |
| Hoxc8 | homeobox C8 | 0.670 | |
| Tbx2 | T-box 2 | 0.667 | |
| Hoxd13 | homeobox D13 | 0.624 | |
| Ednra | endothelin receptor type A | 0.610 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.595 | |
| T | brachyury | 0.583 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.582 | |
| Sox11 | SRY-box containing gene 11 | 0.575 | |
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.565 | |
| Hoxb5 | homeobox B5 | 0.550 | |
| Chrd | chordin | 0.539 | |
| Foxg1 | forkhead box G1 | 0.527 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.514 | |
| Meox2 | mesenchyme homeobox 2 | 0.513 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.502 | |
| Lhx3 | LIM homeobox protein 3 | 0.495 | |
| Tbx3 | T-box 3 | 0.494 | |
| Hoxc4 | homeobox C4 | 0.485 | |
| Foxf2 | forkhead box F2 | 0.476 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.471 | |
| Nodal | nodal | 0.468 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.466 | |
| Vegfa | vascular endothelial growth factor A | 0.455 | |
| Tcfap2c | transcription factor AP-2, gamma | 0.455 | |
| Sox7 | SRY-box containing gene 7 | 0.450 | |
| Ar | androgen receptor | 0.445 | |
| Bnc1 | basonuclin 1 | 0.416 | |
| Hoxb4 | homeobox B4 | 0.415 | |
| Hoxc9 | homeobox C9 | 0.414 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.402 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| NRP1 | neuropilin 1 | 0.981 | |
| ENG | endoglin | 0.962 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.962 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.714 | |
| FSTL1 | follistatin-like 1 | 0.704 | |
| PJA1 | praja ring finger 1 | 0.601 | |
| MAGED2 | melanoma antigen family D, 2 | 0.452 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.395 | |
| PGF | placental growth factor | 0.171 | |
| NKX2-1 | NK2 homeobox 1 | 0.157 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.123 | |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.117 | |
| TGFB3 | transforming growth factor, beta 3 | 0.088 | |
| XIAP | X-linked inhibitor of apoptosis | 0.068 | |
| BMP7 | bone morphogenetic protein 7 | 0.054 | |
| BMP2 | bone morphogenetic protein 2 | 0.054 | |
| THBS1 | thrombospondin 1 | 0.048 | |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.047 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.047 | |
| MDFI | MyoD family inhibitor | 0.044 | |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 | 0.041 | |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.038 | |
| C5orf13 | chromosome 5 open reading frame 13 | 0.034 | |
| NOTCH1 | notch 1 | 0.034 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.033 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.033 | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.031 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.028 | |
| BBS1 | Bardet-Biedl syndrome 1 | 0.027 | |
| HOXB5 | homeobox B5 | 0.027 | |
| SMAD7 | SMAD family member 7 | 0.024 | |
| HOXB6 | homeobox B6 | 0.022 | |
| HOXA11 | homeobox A11 | 0.021 | |
| TGFBR3 | transforming growth factor, beta receptor III | 0.021 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.021 | |
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.020 | |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.020 | |
| SSR1 | signal sequence receptor, alpha | 0.020 | |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.020 | |
| WNT7A | wingless-type MMTV integration site family, member 7A | 0.019 | |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.019 | |
| HNF1A | HNF1 homeobox A | 0.018 | |
| NDNL2 | necdin-like 2 | 0.018 | |
| EYA2 | eyes absent homolog 2 (Drosophila) | 0.018 | |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.017 | |
| HOXB9 | homeobox B9 | 0.017 | |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.017 | |
| COL2A1 | collagen, type II, alpha 1 | 0.017 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.016 | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.016 | |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.016 | |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.016 | |
| TGFB2 | transforming growth factor, beta 2 | 0.016 | |
| COPG2 | coatomer protein complex, subunit gamma 2 | 0.015 | |
| AKNA | AT-hook transcription factor | 0.015 | |
| EFNA1 | ephrin-A1 | 0.015 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.015 | |
| EYA1 | eyes absent homolog 1 (Drosophila) | 0.015 | |
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.014 | |
| ARRB1 | arrestin, beta 1 | 0.014 | |
| SIM2 | single-minded homolog 2 (Drosophila) | 0.014 | |
| LHX1 | LIM homeobox 1 | 0.014 | |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.014 | |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.014 | |
| WT1 | Wilms tumor 1 | 0.014 | |
| PAX7 | paired box 7 | 0.013 | |
| LDLR | low density lipoprotein receptor | 0.013 | |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.013 | |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.013 | |
| PAEP | progestagen-associated endometrial protein | 0.013 | |
| INHBB | inhibin, beta B | 0.013 | |
| SHB | Src homology 2 domain containing adaptor protein B | 0.013 | |
| FOXA2 | forkhead box A2 | 0.013 | |
| BBS4 | Bardet-Biedl syndrome 4 | 0.013 | |
| TBCD | tubulin folding cofactor D | 0.013 | |
| CD14 | CD14 molecule | 0.013 | |
| COPG | coatomer protein complex, subunit gamma | 0.012 | |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.012 | |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.012 | |
| VTN | vitronectin | 0.012 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.012 | |
| STC2 | stanniocalcin 2 | 0.011 | |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.011 | |
| NDRG1 | N-myc downstream regulated 1 | 0.011 | |
| USF1 | upstream transcription factor 1 | 0.011 | |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.011 | |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 0.011 | |
| GFRA3 | GDNF family receptor alpha 3 | 0.011 | |
| HNF1B | HNF1 homeobox B | 0.011 | |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.011 | |
| FOXF1 | forkhead box F1 | 0.011 | |
| ILVBL | ilvB (bacterial acetolactate synthase)-like | 0.010 | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.010 | |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.010 | |
| CLU | clusterin | 0.010 | |
| LAMC3 | laminin, gamma 3 | 0.010 | |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.010 | |
| MYOD1 | myogenic differentiation 1 | 0.010 |