IMP
Process View
signal transduction involved in mitotic dna damage checkpoint
Any intracellular signal transduction that is involved in mitotic DNA damage checkpoint.
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Click on a gene's description to view its network relationships with genes known to be involved in "signal transduction involved in mitotic dna damage checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.945 | ||
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.920 | Human | |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.859 | ||
| TP53 | tumor protein p53 | 0.858 | Mouse | |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.834 | ||
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.703 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.520 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.514 | ||
| XIAP | X-linked inhibitor of apoptosis | 0.490 | ||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.490 | ||
| RB1 | retinoblastoma 1 | 0.444 | ||
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.378 | Human | |
| LRDD | leucine-rich repeats and death domain containing | 0.325 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.325 | Human | |
| BRCA1 | breast cancer 1, early onset | 0.161 | ||
| NLRC4 | NLR family, CARD domain containing 4 | 0.152 | ||
| POU3F2 | POU class 3 homeobox 2 | 0.151 | ||
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.129 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.127 | ||
| PAX3 | paired box 3 | 0.125 | ||
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.123 | Human | |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.101 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.100 | ||
| SMAD7 | SMAD family member 7 | 0.091 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.086 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.085 | Human | |
| IER3 | immediate early response 3 | 0.083 | ||
| APAF1 | apoptotic peptidase activating factor 1 | 0.076 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.065 | ||
| POU5F1 | POU class 5 homeobox 1 | 0.061 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.049 | ||
| DAXX | death-domain associated protein | 0.040 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.035 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.033 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.032 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.027 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.026 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.025 | ||
| FADD | Fas (TNFRSF6)-associated via death domain | 0.022 | ||
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.021 | Human | |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.021 | Human | |
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.021 | ||
| FOXD3 | forkhead box D3 | 0.019 | ||
| NBN | nibrin | 0.018 | ||
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.018 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.018 | ||
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.018 | ||
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.017 | ||
| CSNK1A1 | casein kinase 1, alpha 1 | 0.017 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.016 | ||
| MEOX2 | mesenchyme homeobox 2 | 0.015 | ||
| DZIP1 | DAZ interacting protein 1 | 0.015 | ||
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.015 | ||
| NOTCH1 | notch 1 | 0.015 | ||
| ATM | ataxia telangiectasia mutated | 0.014 | ||
| SMC1A | structural maintenance of chromosomes 1A | 0.013 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.012 | ||
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.012 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.012 | ||
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | 0.011 | ||
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.011 | ||
| BIRC2 | baculoviral IAP repeat containing 2 | 0.011 | ||
| MARCKSL1 | MARCKS-like 1 | 0.010 | ||
| AXIN1 | axin 1 | 0.010 | ||
| CCND3 | cyclin D3 | 0.010 | ||
| IFI16 | interferon, gamma-inducible protein 16 | 0.010 |