IMP

Process View

Homo sapiens

2 genes annotated in human

venous blood vessel development

The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "venous blood vessel development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "venous blood vessel development" (in gray)

Name	Description	Probability	Func Analog Organism
TBX5	T-box 5	0.963	Human
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.956
NRP1	neuropilin 1	0.922
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.920	Mouse
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.805
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.768
JAG1	jagged 1	0.669
NOTCH3	notch 3	0.558
PBX1	pre-B-cell leukemia homeobox 1	0.539
TGFB1	transforming growth factor, beta 1	0.534
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.437
HNF4A	hepatocyte nuclear factor 4, alpha	0.429
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.337
GATA4	GATA binding protein 4	0.268
PRKG1	protein kinase, cGMP-dependent, type I	0.189
MAPK8	mitogen-activated protein kinase 8	0.143
MAML1	mastermind-like 1 (Drosophila)	0.101
NCOA7	nuclear receptor coactivator 7	0.097
ARNT	aryl hydrocarbon receptor nuclear translocator	0.082
XIAP	X-linked inhibitor of apoptosis	0.072
PGF	placental growth factor	0.060
MEIS2	Meis homeobox 2	0.052
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.052
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.047
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.045
TGFBR1	transforming growth factor, beta receptor 1	0.044
CTBP2	C-terminal binding protein 2	0.043
JAG2	jagged 2	0.042
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.041
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.038
SOX18	SRY (sex determining region Y)-box 18	0.037
NOTCH2	notch 2	0.035
CDH5	cadherin 5, type 2 (vascular endothelium)	0.034
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.034
HNF1A	HNF1 homeobox A	0.031
E2F2	E2F transcription factor 2	0.029
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.026
CUX1	cut-like homeobox 1	0.025
EPAS1	endothelial PAS domain protein 1	0.024
TBX2	T-box 2	0.024	Human
PALLD	palladin, cytoskeletal associated protein	0.023
GATA5	GATA binding protein 5	0.022
HOXA9	homeobox A9	0.021
BMPR1A	bone morphogenetic protein receptor, type IA	0.021
VEGFC	vascular endothelial growth factor C	0.020
SMAD7	SMAD family member 7	0.020
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.020
FOXC1	forkhead box C1	0.020
ESAM	endothelial cell adhesion molecule	0.019
TBX1	T-box 1	0.019	Human
THBS1	thrombospondin 1	0.018
STAB1	stabilin 1	0.018
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.018
STC1	stanniocalcin 1	0.018
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.017
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.017
PALM2-AKAP2	PALM2-AKAP2 readthrough	0.017
MSX1	msh homeobox 1	0.016
PURA	purine-rich element binding protein A	0.016
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.016
FLT4	fms-related tyrosine kinase 4	0.016	Zebrafish
DUSP6	dual specificity phosphatase 6	0.015
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.015
E2F3	E2F transcription factor 3	0.015
SIX2	SIX homeobox 2	0.015
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.015
HOXD9	homeobox D9	0.015
DDIT4	DNA-damage-inducible transcript 4	0.015
ATXN1L	ataxin 1-like	0.014
FSTL1	follistatin-like 1	0.014
NKG7	natural killer cell group 7 sequence	0.014
RUNX3	runt-related transcription factor 3	0.014
PRSS23	protease, serine, 23	0.014
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.014
ANGPTL2	angiopoietin-like 2	0.014
BMP6	bone morphogenetic protein 6	0.014
TGFB3	transforming growth factor, beta 3	0.013
COL6A1	collagen, type VI, alpha 1	0.013
PYY	peptide YY	0.013
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.013
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.013
LBX1	ladybird homeobox 1	0.013
VEGFA	vascular endothelial growth factor A	0.013	Mouse
FOXF1	forkhead box F1	0.013
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.013
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.012
HOXC11	homeobox C11	0.012
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.012
DLX4	distal-less homeobox 4	0.012
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.012
HOXD11	homeobox D11	0.012
FOXL1	forkhead box L1	0.012
DLL4	delta-like 4 (Drosophila)	0.012	Zebrafish
CXCR6	chemokine (C-X-C motif) receptor 6	0.012
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.012
FGF18	fibroblast growth factor 18	0.012
HOXB13	homeobox B13	0.012
SCARB2	scavenger receptor class B, member 2	0.012
PDGFA	platelet-derived growth factor alpha polypeptide	0.012
TLX1	T-cell leukemia homeobox 1	0.012
ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	0.012
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.011
MCAM	melanoma cell adhesion molecule	0.011
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.011
FRK	fyn-related kinase	0.011
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.011
FZD10	frizzled homolog 10 (Drosophila)	0.011
FOXA2	forkhead box A2	0.011
COL13A1	collagen, type XIII, alpha 1	0.011
GPR4	G protein-coupled receptor 4	0.011
RG9MTD3	RNA (guanine-9-) methyltransferase domain containing 3	0.011
EFNB2	ephrin-B2	0.011
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.011
MAGED1	melanoma antigen family D, 1	0.011
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.011
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.011
ACAN	aggrecan	0.011
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.011
GDF11	growth differentiation factor 11	0.011
HOXB7	homeobox B7	0.011
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.011
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.011
EGFL7	EGF-like-domain, multiple 7	0.011
HOXA11	homeobox A11	0.011
CALCR	calcitonin receptor	0.011
EP300	E1A binding protein p300	0.010
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.010
STC2	stanniocalcin 2	0.010
INHBB	inhibin, beta B	0.010
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.010
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.010
TGFBR3	transforming growth factor, beta receptor III	0.010
COL5A3	collagen, type V, alpha 3	0.010
CSPG4	chondroitin sulfate proteoglycan 4	0.010
COL2A1	collagen, type II, alpha 1	0.010
CIR1	corepressor interacting with RBPJ, 1	0.010
HOXC8	homeobox C8	0.010
TBX3	T-box 3	0.010
TBX20	T-box 20	0.010
NKX3-2	NK3 homeobox 2	0.010
HOXD12	homeobox D12	0.010
FNDC3B	fibronectin type III domain containing 3B	0.010
ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	0.010
PLXDC1	plexin domain containing 1	0.010
PHOX2B	paired-like homeobox 2b	0.010
LTK	leukocyte receptor tyrosine kinase	0.010
TBX21	T-box 21	0.010	Human
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.010