IMP

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of natural killer cell mediated immunity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of natural killer cell mediated immunity" (in gray)

Name	Description	Probability	Func Analog Organism
HLA-C	major histocompatibility complex, class I, C	1.000	Human
HLA-G	major histocompatibility complex, class I, G	0.999	Human
B2M	beta-2-microglobulin	0.997
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.991
HLA-A	major histocompatibility complex, class I, A	0.975
CD84	CD84 molecule	0.945
TAPBP	TAP binding protein (tapasin)	0.872
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.871
HLA-B	major histocompatibility complex, class I, B	0.825
HLA-E	major histocompatibility complex, class I, E	0.747
HLA-F	major histocompatibility complex, class I, F	0.563	Human
PILRA	paired immunoglobin-like type 2 receptor alpha	0.493
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.447	Human
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.353
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.220
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.216	Human
IL2RB	interleukin 2 receptor, beta	0.177
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.130	Human
GBA	glucosidase, beta, acid	0.111
PVRL4	poliovirus receptor-related 4	0.103
SIGLEC7	sialic acid binding Ig-like lectin 7	0.101
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.087	Human
SLAMF1	signaling lymphocytic activation molecule family member 1	0.086
PTAFR	platelet-activating factor receptor	0.076
IL23A	interleukin 23, alpha subunit p19	0.075
HK3	hexokinase 3 (white cell)	0.069
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.064	Rat
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.061
FYB	FYN binding protein	0.057
KLRC2	killer cell lectin-like receptor subfamily C, member 2	0.051	Human
GRN	granulin	0.050
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.050
PSAP	prosaposin	0.048
GZMK	granzyme K (granzyme 3; tryptase II)	0.044
KLRC3	killer cell lectin-like receptor subfamily C, member 3	0.044	Human
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.043
INSR	insulin receptor	0.043
IFNG	interferon, gamma	0.042
ITM2B	integral membrane protein 2B	0.042
TPP1	tripeptidyl peptidase I	0.038
NCSTN	nicastrin	0.033
ARRB2	arrestin, beta 2	0.033
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.032
STAP2	signal transducing adaptor family member 2	0.031
NPC2	Niemann-Pick disease, type C2	0.030
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.030
IL18RAP	interleukin 18 receptor accessory protein	0.025
GNS	glucosamine (N-acetyl)-6-sulfatase	0.024
NLRP3	NLR family, pyrin domain containing 3	0.023
EPOR	erythropoietin receptor	0.022
GNLY	granulysin	0.021
AOAH	acyloxyacyl hydrolase (neutrophil)	0.020
PVRL3	poliovirus receptor-related 3	0.020	Human
CD33	CD33 molecule	0.020
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.018	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.018
ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.018
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.018
CTSA	cathepsin A	0.018
PRF1	perforin 1 (pore forming protein)	0.018
MAPK10	mitogen-activated protein kinase 10	0.017
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.017
CCR1	chemokine (C-C motif) receptor 1	0.016
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.016
SIRPB1	signal-regulatory protein beta 1	0.015
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.015
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.014
CD226	CD226 molecule	0.014
RAB14	RAB14, member RAS oncogene family	0.014
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.014
TAPBPL	TAP binding protein-like	0.014
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.013
CCL5	chemokine (C-C motif) ligand 5	0.013
BTN3A1	butyrophilin, subfamily 3, member A1	0.013
CXCR6	chemokine (C-X-C motif) receptor 6	0.012
FPR1	formyl peptide receptor 1	0.012
XCL2	chemokine (C motif) ligand 2	0.012
CD86	CD86 molecule	0.011
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.011
CMKLR1	chemokine-like receptor 1	0.011
HCST	hematopoietic cell signal transducer	0.011
SIGLEC9	sialic acid binding Ig-like lectin 9	0.011
TREM1	triggering receptor expressed on myeloid cells 1	0.011
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.011
TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.011	Rat
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.011	Human
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.011
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.011
PGCP	plasma glutamate carboxypeptidase	0.010
KLRF1	killer cell lectin-like receptor subfamily F, member 1	0.010
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.010	Human
BCAR1	breast cancer anti-estrogen resistance 1	0.010
KLRC1	killer cell lectin-like receptor subfamily C, member 1	0.010	Human
ASGR2	asialoglycoprotein receptor 2	0.010
BIN2	bridging integrator 2	0.010
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.010