IMP

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Homo sapiens

18 genes annotated in human

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cardiac muscle tissue morphogenesis

GO:0055008

The process in which the anatomical structures of cardiac muscle tissue are generated and organized.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cardiac muscle tissue morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cardiac muscle tissue morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
TRIM63	tripartite motif containing 63	1.000
TNNI1	troponin I type 1 (skeletal, slow)	0.999	Human Mouse
TNNC1	troponin C type 1 (slow)	0.997
TTN	titin	0.985
TPM1	tropomyosin 1 (alpha)	0.973
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.895
ACTA1	actin, alpha 1, skeletal muscle	0.812
TNNI2	troponin I type 2 (skeletal, fast)	0.787	Human
TCAP	titin-cap (telethonin)	0.781
RARA	retinoic acid receptor, alpha	0.772
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.726
TNNT2	troponin T type 2 (cardiac)	0.673
CKM	creatine kinase, muscle	0.629
SMYD1	SET and MYND domain containing 1	0.625
DSP	desmoplakin	0.623	Mouse
ESR2	estrogen receptor 2 (ER beta)	0.613
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.594
ACTN2	actinin, alpha 2	0.594
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.558
DES	desmin	0.512
COX6A2	cytochrome c oxidase subunit VIa polypeptide 2	0.511
TBX5	T-box 5	0.506
TNNT3	troponin T type 3 (skeletal, fast)	0.495	Human
TPM2	tropomyosin 2 (beta)	0.489	Human
TNNT1	troponin T type 1 (skeletal, slow)	0.453	Human
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.446
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.433
MYOD1	myogenic differentiation 1	0.413
MYOZ1	myozenin 1	0.382
MYH9	myosin, heavy chain 9, non-muscle	0.374
LDB3	LIM domain binding 3	0.358
NOTCH1	notch 1	0.333	Mouse
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.316
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.312
NEB	nebulin	0.302
JAG1	jagged 1	0.297
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.267
BMPR1A	bone morphogenetic protein receptor, type IA	0.261
TNNC2	troponin C type 2 (fast)	0.246	Human
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.236	Human
MYBPC2	myosin binding protein C, fast type	0.213
ACVR1B	activin A receptor, type IB	0.206
INADL	InaD-like (Drosophila)	0.201
HAP1	huntingtin-associated protein 1	0.181
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.179	Mouse
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.170	Human
SFN	stratifin	0.170
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.154
EP300	E1A binding protein p300	0.151
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.150
PKP2	plakophilin 2	0.148
GSK3B	glycogen synthase kinase 3 beta	0.133
FGF10	fibroblast growth factor 10	0.133
EPAS1	endothelial PAS domain protein 1	0.132
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.130	Human
FSTL1	follistatin-like 1	0.108
MYH1	myosin, heavy chain 1, skeletal muscle, adult	0.103	Human
ACTC1	actin, alpha, cardiac muscle 1	0.101
SMAD3	SMAD family member 3	0.096
KRT14	keratin 14	0.094
FLNC	filamin C, gamma	0.091
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.091
ACTN3	actinin, alpha 3	0.088
PDLIM7	PDZ and LIM domain 7 (enigma)	0.087
ANK1	ankyrin 1, erythrocytic	0.085
MYBPC1	myosin binding protein C, slow type	0.083
MYOG	myogenin (myogenic factor 4)	0.081
CXXC5	CXXC finger protein 5	0.078
SETD8	SET domain containing (lysine methyltransferase) 8	0.076
CTGF	connective tissue growth factor	0.070
PSEN1	presenilin 1	0.069
MYBPH	myosin binding protein H	0.069
CALD1	caldesmon 1	0.068
ESR1	estrogen receptor 1	0.067
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.060
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.060
TCF4	transcription factor 4	0.058
JUP	junction plakoglobin	0.053
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.050
MYH2	myosin, heavy chain 2, skeletal muscle, adult	0.048	Human
TNNI3	troponin I type 3 (cardiac)	0.048
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.046	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.046
TPM4	tropomyosin 4	0.045	Human
CREBBP	CREB binding protein	0.045
TGFBR1	transforming growth factor, beta receptor 1	0.045
PAX8	paired box 8	0.042
NOTCH3	notch 3	0.042
CAPN3	calpain 3, (p94)	0.040
GATA4	GATA binding protein 4	0.039	Zebrafish
MYLK	myosin light chain kinase	0.038
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.037	Human
GATA2	GATA binding protein 2	0.037
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.036
HNF4A	hepatocyte nuclear factor 4, alpha	0.035
PDX1	pancreatic and duodenal homeobox 1	0.035
TGFB1	transforming growth factor, beta 1	0.033
TAGLN	transgelin	0.033
OBSL1	obscurin-like 1	0.033
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.033
VCL	vinculin	0.030
MYH4	myosin, heavy chain 4, skeletal muscle	0.030	Human
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.030
MYL7	myosin, light chain 7, regulatory	0.030	Human
PGAM2	phosphoglycerate mutase 2 (muscle)	0.029
RUNX1	runt-related transcription factor 1	0.029
SLN	sarcolipin	0.029
MARK3	MAP/microtubule affinity-regulating kinase 3	0.028
MRPL41	mitochondrial ribosomal protein L41	0.028
MYOZ2	myozenin 2	0.027
MYPN	myopalladin	0.027
MAML1	mastermind-like 1 (Drosophila)	0.027
CAV3	caveolin 3	0.027
CORO1C	coronin, actin binding protein, 1C	0.026
SP1	Sp1 transcription factor	0.025
COL4A1	collagen, type IV, alpha 1	0.025
KRT8	keratin 8	0.024
SMAD6	SMAD family member 6	0.024
ACTN1	actinin, alpha 1	0.023
PALLD	palladin, cytoskeletal associated protein	0.022
KRT18	keratin 18	0.022
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.022	Human
MYBPC3	myosin binding protein C, cardiac	0.022
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.022
EGFR	epidermal growth factor receptor	0.022
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.021
CNN2	calponin 2	0.021
CNN1	calponin 1, basic, smooth muscle	0.021
FRMD5	FERM domain containing 5	0.021
LAD1	ladinin 1	0.021
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.020
SNW1	SNW domain containing 1	0.019
COL4A2	collagen, type IV, alpha 2	0.018
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.018
APC	adenomatous polyposis coli	0.018
TBX1	T-box 1	0.017
SOX11	SRY (sex determining region Y)-box 11	0.017
HOXD12	homeobox D12	0.017
SKIL	SKI-like oncogene	0.016
DSC2	desmocollin 2	0.016
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.016
FGF7	fibroblast growth factor 7	0.016
MYOM1	myomesin 1, 185kDa	0.016
FOXA2	forkhead box A2	0.016
LMO2	LIM domain only 2 (rhombotin-like 1)	0.015
WNT3A	wingless-type MMTV integration site family, member 3A	0.015
SMPX	small muscle protein, X-linked	0.015
TNNI3K	TNNI3 interacting kinase	0.015
RPL3L	ribosomal protein L3-like	0.014
CDX2	caudal type homeobox 2	0.014
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.014
CHUK	conserved helix-loop-helix ubiquitous kinase	0.014
NCOA1	nuclear receptor coactivator 1	0.014
CASQ2	calsequestrin 2 (cardiac muscle)	0.014
ATXN1L	ataxin 1-like	0.014
SIX6	SIX homeobox 6	0.014
NCOR2	nuclear receptor corepressor 2	0.014
CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)	0.013
MYF5	myogenic factor 5	0.013
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.013
MED25	mediator complex subunit 25	0.013
EGLN3	egl nine homolog 3 (C. elegans)	0.013
KRT5	keratin 5	0.013
FGF3	fibroblast growth factor 3	0.013
SRPK3	SRSF protein kinase 3	0.013
PRKD2	protein kinase D2	0.013
SYNPO2L	synaptopodin 2-like	0.013
SOX7	SRY (sex determining region Y)-box 7	0.012
MB	myoglobin	0.012
ZYX	zyxin	0.012
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.012
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.012
TNS4	tensin 4	0.012
PHOX2A	paired-like homeobox 2a	0.012
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.012
MYL9	myosin, light chain 9, regulatory	0.012	Human
MYF6	myogenic factor 6 (herculin)	0.012
MNX1	motor neuron and pancreas homeobox 1	0.012
SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	0.012
SMAD5	SMAD family member 5	0.012
APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.012
SSX4	synovial sarcoma, X breakpoint 4	0.012
NPPB	natriuretic peptide B	0.012
CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.012
LHX5	LIM homeobox 5	0.012
DSG2	desmoglein 2	0.012
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.011
TCF15	transcription factor 15 (basic helix-loop-helix)	0.011	Human
FOXG1	forkhead box G1	0.011
FZD1	frizzled homolog 1 (Drosophila)	0.011
ATXN3	ataxin 3	0.011
ENO3	enolase 3 (beta, muscle)	0.011
SFRP5	secreted frizzled-related protein 5	0.011
NKX6-1	NK6 homeobox 1	0.011
ITGB1BP3	integrin beta 1 binding protein 3	0.011
USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	0.011
UBXN2A	UBX domain protein 2A	0.011
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.011
NPAS1	neuronal PAS domain protein 1	0.011
AKAP6	A kinase (PRKA) anchor protein 6	0.011
PKP4	plakophilin 4	0.010	Human
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.010
SRL	sarcalumenin	0.010
HTT	huntingtin	0.010
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.010	Human
CFL1	cofilin 1 (non-muscle)	0.010