IMP
Process View
cell fate commitment involved in formation of primary germ layer
The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cell fate commitment involved in formation of primary germ layer"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| POU3F2 | POU class 3 homeobox 2 | 0.985 | Human | |
| SMAD7 | SMAD family member 7 | 0.984 | ||
| BMP2 | bone morphogenetic protein 2 | 0.971 | Zebrafish | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.966 | Mouse Worm | |
| PAX3 | paired box 3 | 0.962 | ||
| FGF1 | fibroblast growth factor 1 (acidic) | 0.926 | ||
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.917 | Worm | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.912 | Worm | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.907 | Mouse Fly | |
| LCK | lymphocyte-specific protein tyrosine kinase | 0.784 | Worm | |
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.773 | Worm | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.738 | ||
| SP1 | Sp1 transcription factor | 0.720 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.605 | Worm | |
| MEIS1 | Meis homeobox 1 | 0.598 | Worm | |
| SMAD3 | SMAD family member 3 | 0.495 | ||
| CSNK1E | casein kinase 1, epsilon | 0.471 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.455 | ||
| SMAD2 | SMAD family member 2 | 0.380 | ||
| POU5F1 | POU class 5 homeobox 1 | 0.351 | ||
| SOX2 | SRY (sex determining region Y)-box 2 | 0.345 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.327 | Human | |
| SMAD5 | SMAD family member 5 | 0.299 | Fly | |
| SMAD4 | SMAD family member 4 | 0.296 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.265 | ||
| FOXD3 | forkhead box D3 | 0.257 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.255 | ||
| BMP7 | bone morphogenetic protein 7 | 0.230 | Zebrafish | |
| WNT3A | wingless-type MMTV integration site family, member 3A | 0.219 | ||
| JAG1 | jagged 1 | 0.214 | ||
| SOX10 | SRY (sex determining region Y)-box 10 | 0.188 | Human | |
| NOG | noggin | 0.176 | Zebrafish | |
| APC | adenomatous polyposis coli | 0.166 | Worm | |
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.166 | Worm | |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.161 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.154 | ||
| AXIN1 | axin 1 | 0.147 | ||
| LEO1 | Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.122 | ||
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.115 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.108 | Zebrafish Mouse Fly | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.103 | Worm | |
| FSTL1 | follistatin-like 1 | 0.101 | ||
| CREBBP | CREB binding protein | 0.099 | ||
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.097 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.089 | ||
| NLK | nemo-like kinase | 0.088 | Worm | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.088 | ||
| AR | androgen receptor | 0.086 | ||
| SMAD1 | SMAD family member 1 | 0.086 | Mouse Fly | |
| HOXA10 | homeobox A10 | 0.078 | ||
| HIC1 | hypermethylated in cancer 1 | 0.078 | ||
| MEIS2 | Meis homeobox 2 | 0.077 | Worm | |
| WT1 | Wilms tumor 1 | 0.066 | ||
| HCK | hemopoietic cell kinase | 0.066 | ||
| EP300 | E1A binding protein p300 | 0.064 | ||
| NOTCH3 | notch 3 | 0.064 | ||
| SMAD6 | SMAD family member 6 | 0.063 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.060 | ||
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.060 | ||
| MEOX2 | mesenchyme homeobox 2 | 0.054 | ||
| SYK | spleen tyrosine kinase | 0.051 | ||
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.047 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.045 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.045 | ||
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.043 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.042 | ||
| HOXA9 | homeobox A9 | 0.035 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.034 | ||
| FZD8 | frizzled homolog 8 (Drosophila) | 0.032 | Human | |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.031 | Worm | |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.030 | ||
| SFRP1 | secreted frizzled-related protein 1 | 0.030 | ||
| BTRC | beta-transducin repeat containing | 0.029 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.027 | ||
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.027 | Human | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.026 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.025 | ||
| GLIS2 | GLIS family zinc finger 2 | 0.025 | ||
| HNF1A | HNF1 homeobox A | 0.024 | ||
| SOX9 | SRY (sex determining region Y)-box 9 | 0.024 | Human | |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.022 | Human | |
| INHBB | inhibin, beta B | 0.022 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.022 | ||
| DUSP1 | dual specificity phosphatase 1 | 0.022 | ||
| FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.021 | ||
| MYB | v-myb myeloblastosis viral oncogene homolog (avian) | 0.020 | ||
| FGF2 | fibroblast growth factor 2 (basic) | 0.020 | ||
| GDF5 | growth differentiation factor 5 | 0.020 | ||
| SIM2 | single-minded homolog 2 (Drosophila) | 0.020 | ||
| NDP | Norrie disease (pseudoglioma) | 0.019 | ||
| FOXC1 | forkhead box C1 | 0.019 | ||
| TCF4 | transcription factor 4 | 0.018 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.018 | ||
| OTP | orthopedia homeobox | 0.018 | ||
| MSX1 | msh homeobox 1 | 0.017 | ||
| ZNF512B | zinc finger protein 512B | 0.016 | ||
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.016 | ||
| FOXF2 | forkhead box F2 | 0.015 | ||
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.015 | ||
| FGFR2 | fibroblast growth factor receptor 2 | 0.015 | Fly | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.015 | ||
| FGF10 | fibroblast growth factor 10 | 0.015 | ||
| FOXA2 | forkhead box A2 | 0.014 | ||
| NFIB | nuclear factor I/B | 0.014 | ||
| GATA5 | GATA binding protein 5 | 0.014 | ||
| POU3F1 | POU class 3 homeobox 1 | 0.014 | Human | |
| RAX | retina and anterior neural fold homeobox | 0.014 | ||
| BMP4 | bone morphogenetic protein 4 | 0.014 | Zebrafish Mouse | |
| HOXD9 | homeobox D9 | 0.014 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.014 | ||
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.013 | ||
| RBPMS | RNA binding protein with multiple splicing | 0.013 | ||
| HCFC1 | host cell factor C1 (VP16-accessory protein) | 0.013 | ||
| LBX1 | ladybird homeobox 1 | 0.013 | ||
| FBLN1 | fibulin 1 | 0.013 | ||
| PSEN1 | presenilin 1 | 0.012 | ||
| FGFR3 | fibroblast growth factor receptor 3 | 0.012 | Fly | |
| GRB7 | growth factor receptor-bound protein 7 | 0.012 | ||
| GAS7 | growth arrest-specific 7 | 0.012 | ||
| HOXA5 | homeobox A5 | 0.012 | ||
| FGF7 | fibroblast growth factor 7 | 0.012 | ||
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.012 | ||
| SOX1 | SRY (sex determining region Y)-box 1 | 0.012 | Human | |
| CTGF | connective tissue growth factor | 0.012 | ||
| JUP | junction plakoglobin | 0.011 | Worm | |
| HOXD13 | homeobox D13 | 0.011 | ||
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.011 | ||
| FOXF1 | forkhead box F1 | 0.011 | ||
| NCOA2 | nuclear receptor coactivator 2 | 0.011 | ||
| MYOD1 | myogenic differentiation 1 | 0.011 | ||
| MARCKSL1 | MARCKS-like 1 | 0.011 | ||
| POU3F3 | POU class 3 homeobox 3 | 0.010 | Human |