IMP

Process View

Homo sapiens

4 genes annotated in human

Multi-species View

regulation of icosanoid secretion

GO:0032303

Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of icosanoid secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of icosanoid secretion" (in gray)

Name	Description	Probability	Func Analog Organism
MAP2K4	mitogen-activated protein kinase kinase 4	0.601
BLNK	B-cell linker	0.597
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.581
IL1R1	interleukin 1 receptor, type I	0.505
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.393
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.334
UBASH3B	ubiquitin associated and SH3 domain containing B	0.314
XPO7	exportin 7	0.312
SC4MOL	sterol-C4-methyl oxidase-like	0.254
LAT	linker for activation of T cells	0.214
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.214
LRRK2	leucine-rich repeat kinase 2	0.207
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.153
MAPK8	mitogen-activated protein kinase 8	0.132
IL1RN	interleukin 1 receptor antagonist	0.086
CD247	CD247 molecule	0.078
KIAA1377	KIAA1377	0.076
BBS10	Bardet-Biedl syndrome 10	0.076
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.069
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.062
SH3KBP1	SH3-domain kinase binding protein 1	0.057
MAPK1	mitogen-activated protein kinase 1	0.056
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.051
PRKCQ	protein kinase C, theta	0.049
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.048	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.047
VAV1	vav 1 guanine nucleotide exchange factor	0.045
MAPK14	mitogen-activated protein kinase 14	0.045
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.043
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.041	Human
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.039
KIAA1712	KIAA1712	0.039
ZBTB25	zinc finger and BTB domain containing 25	0.035
LMO4	LIM domain only 4	0.034
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.033
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.030
DSE	dermatan sulfate epimerase	0.028
TRAF5	TNF receptor-associated factor 5	0.028
SH2D2A	SH2 domain containing 2A	0.027
SH3BP2	SH3-domain binding protein 2	0.026
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.025
SPRY4	sprouty homolog 4 (Drosophila)	0.025
IL8	interleukin 8	0.024
C7orf36	chromosome 7 open reading frame 36	0.023
AQP7	aquaporin 7	0.023
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.023
LCK	lymphocyte-specific protein tyrosine kinase	0.022
C6	complement component 6	0.022
GP2	glycoprotein 2 (zymogen granule membrane)	0.022
SH2B2	SH2B adaptor protein 2	0.021
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.021
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.020
C4BPA	complement component 4 binding protein, alpha	0.018
FGFR1	fibroblast growth factor receptor 1	0.018
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.017
SNRNP35	small nuclear ribonucleoprotein 35kDa (U11/U12)	0.017
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.016
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.016
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.016
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.016
STK39	serine threonine kinase 39	0.016
FMO4	flavin containing monooxygenase 4	0.016
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.016
CCL20	chemokine (C-C motif) ligand 20	0.016
HPD	4-hydroxyphenylpyruvate dioxygenase	0.016
IRAK2	interleukin-1 receptor-associated kinase 2	0.015
BTK	Bruton agammaglobulinemia tyrosine kinase	0.015
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.015
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.015	Human
MBTPS1	membrane-bound transcription factor peptidase, site 1	0.015
YIPF6	Yip1 domain family, member 6	0.015
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.014
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.014
ALOX12	arachidonate 12-lipoxygenase	0.014
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.014
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.014
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.014
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	0.014
AGXT	alanine-glyoxylate aminotransferase	0.014
PIP	prolactin-induced protein	0.013
LGALS4	lectin, galactoside-binding, soluble, 4	0.013
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.013
RNF8	ring finger protein 8	0.013
RGS2	regulator of G-protein signaling 2, 24kDa	0.013
C8A	complement component 8, alpha polypeptide	0.013
PLA2G1B	phospholipase A2, group IB (pancreas)	0.013	Human
RDH16	retinol dehydrogenase 16 (all-trans)	0.013
SLC25A46	solute carrier family 25, member 46	0.013
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.013
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.013
OVGP1	oviductal glycoprotein 1, 120kDa	0.013
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.013
TLR3	toll-like receptor 3	0.013
INSL3	insulin-like 3 (Leydig cell)	0.013
OTC	ornithine carbamoyltransferase	0.013
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.013
FABP1	fatty acid binding protein 1, liver	0.013
TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)	0.013
TMEM41B	transmembrane protein 41B	0.013
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.013
G6PC	glucose-6-phosphatase, catalytic subunit	0.013
FRZB	frizzled-related protein	0.012
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.012
CMIP	c-Maf-inducing protein	0.012
GSTA3	glutathione S-transferase alpha 3	0.012
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.012	Human
MAT1A	methionine adenosyltransferase I, alpha	0.012
BHMT	betaine--homocysteine S-methyltransferase	0.012
KNG1	kininogen 1	0.012
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.012
ATF2	activating transcription factor 2	0.012
TTR	transthyretin	0.012
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	0.011
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.011
STAB2	stabilin 2	0.011
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.011
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.011
PTK6	PTK6 protein tyrosine kinase 6	0.011
MAP2K3	mitogen-activated protein kinase kinase 3	0.011
SIRPB1	signal-regulatory protein beta 1	0.011
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.011
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.011
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.011
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.011
SCGB1D2	secretoglobin, family 1D, member 2	0.011
FOXN1	forkhead box N1	0.011
C8B	complement component 8, beta polypeptide	0.011
PLG	plasminogen	0.011
CRCT1	cysteine-rich C-terminal 1	0.011
HAL	histidine ammonia-lyase	0.011
KRT13	keratin 13	0.011
CCL11	chemokine (C-C motif) ligand 11	0.011
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.011
ACSL3	acyl-CoA synthetase long-chain family member 3	0.011	Human
STARD4	StAR-related lipid transfer (START) domain containing 4	0.011
CD2AP	CD2-associated protein	0.011
STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)	0.011
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.011
BCL3	B-cell CLL/lymphoma 3	0.011
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.011
NSF	N-ethylmaleimide-sensitive factor	0.011
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.011
EPHX2	epoxide hydrolase 2, cytoplasmic	0.011
PANK3	pantothenate kinase 3	0.011
PRODH	proline dehydrogenase (oxidase) 1	0.011
APOF	apolipoprotein F	0.011
DPYS	dihydropyrimidinase	0.011
GPR84	G protein-coupled receptor 84	0.011
GLYAT	glycine-N-acyltransferase	0.011
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.011
ARG1	arginase, liver	0.010
KIAA0232	KIAA0232	0.010
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.010
SCGB2A1	secretoglobin, family 2A, member 1	0.010
CNGA1	cyclic nucleotide gated channel alpha 1	0.010
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.010
APOC3	apolipoprotein C-III	0.010
AQP9	aquaporin 9	0.010
ADH6	alcohol dehydrogenase 6 (class V)	0.010
IL22RA1	interleukin 22 receptor, alpha 1	0.010
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.010
PAH	phenylalanine hydroxylase	0.010
AXL	AXL receptor tyrosine kinase	0.010
SPP2	secreted phosphoprotein 2, 24kDa	0.010
CHAD	chondroadherin	0.010
PLIN1	perilipin 1	0.010
KRT9	keratin 9	0.010
CD38	CD38 molecule	0.010
ADRB3	adrenergic, beta-3-, receptor	0.010
DIO1	deiodinase, iodothyronine, type I	0.010
RHO	rhodopsin	0.010