IMP

Process View

Homo sapiens

12 genes annotated in human

Multi-species View

establishment of spindle localization

GO:0051293

The directed movement of the spindle to a specific location in the cell.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "establishment of spindle localization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "establishment of spindle localization" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.904	Worm
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.454	Worm
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.415	Worm
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.365	Worm
CENPF	centromere protein F, 350/400kDa (mitosin)	0.304
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.195
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.182	Worm
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.182
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.151	Worm
MARK2	MAP/microtubule affinity-regulating kinase 2	0.147
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.134
KIF23	kinesin family member 23	0.128
KIF2C	kinesin family member 2C	0.117	Fly
LRRK2	leucine-rich repeat kinase 2	0.100
APC	adenomatous polyposis coli	0.089
CKAP5	cytoskeleton associated protein 5	0.084
COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.084
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.081
GPSM2	G-protein signaling modulator 2	0.069	Mouse Fly
AXIN1	axin 1	0.065
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.064
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.058
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.050	Worm
KIF1B	kinesin family member 1B	0.047
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.045
CNOT6	CCR4-NOT transcription complex, subunit 6	0.040
TJP2	tight junction protein 2 (zona occludens 2)	0.040
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.039
GDA	guanine deaminase	0.038
KIF18A	kinesin family member 18A	0.037
RHOA	ras homolog gene family, member A	0.036
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.036
SFN	stratifin	0.035
FLNA	filamin A, alpha	0.035
GRB2	growth factor receptor-bound protein 2	0.034
CSNK1E	casein kinase 1, epsilon	0.034
SH3KBP1	SH3-domain kinase binding protein 1	0.032
SYK	spleen tyrosine kinase	0.031
KIF4A	kinesin family member 4A	0.027
CDCA8	cell division cycle associated 8	0.027
PRKCZ	protein kinase C, zeta	0.026
CUL1	cullin 1	0.025
ANAPC7	anaphase promoting complex subunit 7	0.025
EZR	ezrin	0.024	Fly
RACGAP1	Rac GTPase activating protein 1	0.024
AURKA	aurora kinase A	0.024
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.023
NUP62	nucleoporin 62kDa	0.023
PRKCI	protein kinase C, iota	0.023	Zebrafish
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.021
FOXM1	forkhead box M1	0.021
BIRC5	baculoviral IAP repeat containing 5	0.020
ANAPC5	anaphase promoting complex subunit 5	0.020
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.020
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.019
ZBED1	zinc finger, BED-type containing 1	0.019
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.019
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.019
MAP7D1	MAP7 domain containing 1	0.017
C13orf34	chromosome 13 open reading frame 34	0.017
PRC1	protein regulator of cytokinesis 1	0.017
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.016
FBXW11	F-box and WD repeat domain containing 11	0.016
PTTG1	pituitary tumor-transforming 1	0.016
LCK	lymphocyte-specific protein tyrosine kinase	0.016	Worm
ADAM17	ADAM metallopeptidase domain 17	0.016
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.016
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.016	Worm
NUP205	nucleoporin 205kDa	0.016	Worm
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.015
PBK	PDZ binding kinase	0.015
TUBA1C	tubulin, alpha 1c	0.014
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.014
TTK	TTK protein kinase	0.014
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.014
INCENP	inner centromere protein antigens 135/155kDa	0.014
KIF20A	kinesin family member 20A	0.014
SPC25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.014
CENPE	centromere protein E, 312kDa	0.013
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.013
NCF2	neutrophil cytosolic factor 2	0.012
ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1	0.012
KNTC1	kinetochore associated 1	0.012
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.012
ANKRD28	ankyrin repeat domain 28	0.012
CAPNS1	calpain, small subunit 1	0.012
CCDC99	coiled-coil domain containing 99	0.012
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.011
CNOT8	CCR4-NOT transcription complex, subunit 8	0.011
G2E3	G2/M-phase specific E3 ubiquitin protein ligase	0.011
KIF11	kinesin family member 11	0.011
TRIP13	thyroid hormone receptor interactor 13	0.011
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.011	Worm
ZMYND11	zinc finger, MYND-type containing 11	0.010
STARD9	StAR-related lipid transfer (START) domain containing 9	0.010
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.010
SMC6	structural maintenance of chromosomes 6	0.010
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.010