IMP

Process View

Homo sapiens

10 genes annotated in human

cerebral cortex development

GO:0021987

The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cerebral cortex development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cerebral cortex development" (in gray)

Name	Description	Probability	Func Analog Organism
PEX14	peroxisomal biogenesis factor 14	0.937
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.918
DLG4	discs, large homolog 4 (Drosophila)	0.848
PEX19	peroxisomal biogenesis factor 19	0.577
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.555
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.527
LAMB1	laminin, beta 1	0.500
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.440	Human
PAX3	paired box 3	0.348
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.341
TSC2	tuberous sclerosis 2	0.309
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.301	Human Mouse
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.287
AXIN1	axin 1	0.265
LRRK2	leucine-rich repeat kinase 2	0.219
GSK3B	glycogen synthase kinase 3 beta	0.193
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.171	Rat
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.162
CPE	carboxypeptidase E	0.144
BCL2L1	BCL2-like 1	0.142
BBS2	Bardet-Biedl syndrome 2	0.138
BAK1	BCL2-antagonist/killer 1	0.137
MAPT	microtubule-associated protein tau	0.137
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.128
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.123
ASB2	ankyrin repeat and SOCS box containing 2	0.118
VEGFA	vascular endothelial growth factor A	0.111
POU5F1	POU class 5 homeobox 1	0.111
APP	amyloid beta (A4) precursor protein	0.108
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.107
SNAPIN	SNAP-associated protein	0.102
SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	0.099	Mouse
PEX12	peroxisomal biogenesis factor 12	0.098
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.098	Mouse
RPL18A	ribosomal protein L18a	0.096
SORBS3	sorbin and SH3 domain containing 3	0.087
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.084
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.073
APC	adenomatous polyposis coli	0.072
SPTBN4	spectrin, beta, non-erythrocytic 4	0.071
PDIA3	protein disulfide isomerase family A, member 3	0.062
MAP1A	microtubule-associated protein 1A	0.059
BICD1	bicaudal D homolog 1 (Drosophila)	0.057
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.051
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.049
TMEM173	transmembrane protein 173	0.048
LAMA4	laminin, alpha 4	0.046
RTKN	rhotekin	0.045
COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.044
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.044
ASB7	ankyrin repeat and SOCS box containing 7	0.042
RNF144B	ring finger protein 144B	0.041
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.040
PAX8	paired box 8	0.040
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.039
PCDHA4	protocadherin alpha 4	0.038
BBS1	Bardet-Biedl syndrome 1	0.037
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.034
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.032	Rat
CLIP1	CAP-GLY domain containing linker protein 1	0.030
PKP4	plakophilin 4	0.029
C14orf129	chromosome 14 open reading frame 129	0.029
CKAP5	cytoskeleton associated protein 5	0.028
BBS9	Bardet-Biedl syndrome 9	0.025
NIN	ninein (GSK3B interacting protein)	0.025
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.024
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.024
CUL2	cullin 2	0.024
TNRC6A	trinucleotide repeat containing 6A	0.023
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.021
GATAD2B	GATA zinc finger domain containing 2B	0.021
FOXD3	forkhead box D3	0.020
PCM1	pericentriolar material 1	0.020
E2F1	E2F transcription factor 1	0.019
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.019
DEFA1	defensin, alpha 1	0.019
COL5A2	collagen, type V, alpha 2	0.019
RNR2	l-rRNA	0.019
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.018
NCK2	NCK adaptor protein 2	0.018
FBN1	fibrillin 1	0.018
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.018
IGF1R	insulin-like growth factor 1 receptor	0.018
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.018
SIX3	SIX homeobox 3	0.017
NLGN1	neuroligin 1	0.017
ATN1	atrophin 1	0.017
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.017
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.017
CDK5	cyclin-dependent kinase 5	0.016	Mouse
TTC8	tetratricopeptide repeat domain 8	0.016
ASB1	ankyrin repeat and SOCS box containing 1	0.016
EXOC7	exocyst complex component 7	0.016
NTF4	neurotrophin 4	0.016
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.016
SOX10	SRY (sex determining region Y)-box 10	0.015
KIF1C	kinesin family member 1C	0.015
ATXN3	ataxin 3	0.015
SALL2	sal-like 2 (Drosophila)	0.015
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.014
HDAC7	histone deacetylase 7	0.014
COL1A2	collagen, type I, alpha 2	0.013
PAX6	paired box 6	0.013	Mouse
KIAA1191	KIAA1191	0.013
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.013
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.013
PTPRD	protein tyrosine phosphatase, receptor type, D	0.013
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.013
KIAA1377	KIAA1377	0.013
KIF5B	kinesin family member 5B	0.013
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.013
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.013
SYNE1	spectrin repeat containing, nuclear envelope 1	0.012
NCSTN	nicastrin	0.012
KALRN	kalirin, RhoGEF kinase	0.011
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.011
CAMK2B	calcium/calmodulin-dependent protein kinase II beta	0.011
RAB14	RAB14, member RAS oncogene family	0.011
SOX1	SRY (sex determining region Y)-box 1	0.011
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.011
RBMS3	RNA binding motif, single stranded interacting protein 3	0.011
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.011
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.011
LHX2	LIM homeobox 2	0.011	Mouse
ASB6	ankyrin repeat and SOCS box containing 6	0.011
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.010
PCOLCE	procollagen C-endopeptidase enhancer	0.010
LPL	lipoprotein lipase	0.010
BTBD1	BTB (POZ) domain containing 1	0.010
GTSE1	G-2 and S-phase expressed 1	0.010