IMP

Process View

Homo sapiens

3 genes annotated in human

Multi-species View

positive regulation of interleukin 4 production

GO:0032753

Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of interleukin 4 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of interleukin 4 production" (in gray)

Name	Description	Probability	Func Analog Organism
LCK	lymphocyte-specific protein tyrosine kinase	0.885
MED25	mediator complex subunit 25	0.650
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.454
RXRA	retinoid X receptor, alpha	0.447
CD247	CD247 molecule	0.424
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.160
IRAK1	interleukin-1 receptor-associated kinase 1	0.141
BCL3	B-cell CLL/lymphoma 3	0.133
RXRB	retinoid X receptor, beta	0.119
SYK	spleen tyrosine kinase	0.077
STAT2	signal transducer and activator of transcription 2, 113kDa	0.067
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.065
PRKD2	protein kinase D2	0.064
NUMB	numb homolog (Drosophila)	0.062
LAT	linker for activation of T cells	0.057
NCOR2	nuclear receptor corepressor 2	0.052
KLHL24	kelch-like 24 (Drosophila)	0.049
PPARA	peroxisome proliferator-activated receptor alpha	0.048
HDAC7	histone deacetylase 7	0.048
ZNF71	zinc finger protein 71	0.047
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.047
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.045
CD2	CD2 molecule	0.044
HDAC9	histone deacetylase 9	0.044
IRF9	interferon regulatory factor 9	0.043
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.042
CCDC115	coiled-coil domain containing 115	0.040
ISG20	interferon stimulated exonuclease gene 20kDa	0.039
PIAS4	protein inhibitor of activated STAT, 4	0.039
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.038
NCOA1	nuclear receptor coactivator 1	0.036
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.035
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.034
PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	0.034
CREBBP	CREB binding protein	0.030
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.030
IRF2BP2	interferon regulatory factor 2 binding protein 2	0.030
SORBS3	sorbin and SH3 domain containing 3	0.029
KIAA1274	KIAA1274	0.026
MED1	mediator complex subunit 1	0.024
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.024
RARA	retinoic acid receptor, alpha	0.023
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.023
IL15RA	interleukin 15 receptor, alpha	0.022
ADAM15	ADAM metallopeptidase domain 15	0.021
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.021
PRKCZ	protein kinase C, zeta	0.021	Mouse
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.021
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.019
C5orf41	chromosome 5 open reading frame 41	0.019
ISG15	ISG15 ubiquitin-like modifier	0.019
KAT2B	K(lysine) acetyltransferase 2B	0.018
TADA3	transcriptional adaptor 3	0.017
SH2D2A	SH2 domain containing 2A	0.017
PRMT6	protein arginine methyltransferase 6	0.017
PGR	progesterone receptor	0.017
RXRG	retinoid X receptor, gamma	0.016
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.015
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.015
HDAC3	histone deacetylase 3	0.015
VHL	von Hippel-Lindau tumor suppressor	0.015
SH2D1A	SH2 domain containing 1A	0.015
ZBTB38	zinc finger and BTB domain containing 38	0.015
IRF2	interferon regulatory factor 2	0.015	Human
PML	promyelocytic leukemia	0.014
SLC25A36	solute carrier family 25, member 36	0.014
SPIN1	spindlin 1	0.014
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.013
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.013
BCL6	B-cell CLL/lymphoma 6	0.013
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.013
NMT2	N-myristoyltransferase 2	0.013
CD5	CD5 molecule	0.012
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.012	Human
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.012
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.012
EPS8L1	EPS8-like 1	0.012
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.012
PDPK1	3-phosphoinositide dependent protein kinase-1	0.012
TICAM1	toll-like receptor adaptor molecule 1	0.012
JMY	junction mediating and regulatory protein, p53 cofactor	0.011
CCR7	chemokine (C-C motif) receptor 7	0.011
ZNF148	zinc finger protein 148	0.011
TAL1	T-cell acute lymphocytic leukemia 1	0.011
BBX	bobby sox homolog (Drosophila)	0.011
LY86	lymphocyte antigen 86	0.011
NR2F6	nuclear receptor subfamily 2, group F, member 6	0.011
KAT5	K(lysine) acetyltransferase 5	0.011
CD1C	CD1c molecule	0.011
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.011
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.011
MAPK7	mitogen-activated protein kinase 7	0.011
EP300	E1A binding protein p300	0.011
BATF	basic leucine zipper transcription factor, ATF-like	0.010
NR1D1	nuclear receptor subfamily 1, group D, member 1	0.010	Human
RUNX3	runt-related transcription factor 3	0.010
CD38	CD38 molecule	0.010
SOCS1	suppressor of cytokine signaling 1	0.010
FOXK1	forkhead box K1	0.010
TLR7	toll-like receptor 7	0.010
CACNB1	calcium channel, voltage-dependent, beta 1 subunit	0.010
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.010