IMP

Process View

Homo sapiens

13 genes annotated in human

regulation of camp mediated signaling

Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of camp mediated signaling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of camp mediated signaling" (in gray)

Name	Description	Probability	Func Analog Organism
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.999	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.995	Human
CCL5	chemokine (C-C motif) ligand 5	0.995
IL8	interleukin 8	0.994	Human
MPDZ	multiple PDZ domain protein	0.988
CCR5	chemokine (C-C motif) receptor 5	0.979	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.973	Human
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.936
ARRB1	arrestin, beta 1	0.931
CCL20	chemokine (C-C motif) ligand 20	0.895
CXCL9	chemokine (C-X-C motif) ligand 9	0.878
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.866
IL1B	interleukin 1, beta	0.809
IL2RB	interleukin 2 receptor, beta	0.789
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.779
IFNG	interferon, gamma	0.730
IL6	interleukin 6 (interferon, beta 2)	0.725
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.708
CXCR5	chemokine (C-X-C motif) receptor 5	0.608	Human
CCL4	chemokine (C-C motif) ligand 4	0.582
CXCL5	chemokine (C-X-C motif) ligand 5	0.556	Human
CCR2	chemokine (C-C motif) receptor 2	0.542	Human
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.519
CCL22	chemokine (C-C motif) ligand 22	0.352
SSTR3	somatostatin receptor 3	0.315	Human
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.301	Human
DPP4	dipeptidyl-peptidase 4	0.297
CCL8	chemokine (C-C motif) ligand 8	0.291
CCL2	chemokine (C-C motif) ligand 2	0.279
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.228
CXCL10	chemokine (C-X-C motif) ligand 10	0.226
CXCR3	chemokine (C-X-C motif) receptor 3	0.192
IL10	interleukin 10	0.189
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.174
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.164
PF4	platelet factor 4	0.157
SOD2	superoxide dismutase 2, mitochondrial	0.154
CXCL11	chemokine (C-X-C motif) ligand 11	0.140
CCR4	chemokine (C-C motif) receptor 4	0.137	Human
CCL11	chemokine (C-C motif) ligand 11	0.135
CCR7	chemokine (C-C motif) receptor 7	0.108	Human
UBA1	ubiquitin-like modifier activating enzyme 1	0.103
CCL7	chemokine (C-C motif) ligand 7	0.100
CXCL13	chemokine (C-X-C motif) ligand 13	0.097
INF2	inverted formin, FH2 and WH2 domain containing	0.089
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.085
RGS1	regulator of G-protein signaling 1	0.068
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.067
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.066
CD40LG	CD40 ligand	0.066
NCF2	neutrophil cytosolic factor 2	0.064
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.063
CLEC7A	C-type lectin domain family 7, member A	0.059
RAD18	RAD18 homolog (S. cerevisiae)	0.059
CCL19	chemokine (C-C motif) ligand 19	0.057
IRF4	interferon regulatory factor 4	0.053
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.052
PKN2	protein kinase N2	0.050
CD69	CD69 molecule	0.045
SLAMF7	SLAM family member 7	0.045
CCL3	chemokine (C-C motif) ligand 3	0.044
ARRDC3	arrestin domain containing 3	0.044
TNF	tumor necrosis factor	0.042
FBXW5	F-box and WD repeat domain containing 5	0.042
CCR1	chemokine (C-C motif) receptor 1	0.040	Human
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.040
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.039
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.038
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.038
IL7R	interleukin 7 receptor	0.037
VPS29	vacuolar protein sorting 29 homolog (S. cerevisiae)	0.035
BCL2A1	BCL2-related protein A1	0.034
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.033	Human
UBD	ubiquitin D	0.033
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.033
TLR2	toll-like receptor 2	0.030
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.030
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.029
GPR171	G protein-coupled receptor 171	0.028
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.028	Human
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.028
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.027
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.027
CCR9	chemokine (C-C motif) receptor 9	0.027	Human
AQP9	aquaporin 9	0.027
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.026
CXCR4	chemokine (C-X-C motif) receptor 4	0.026	Human
SELL	selectin L	0.025
CYTIP	cytohesin 1 interacting protein	0.025
SSTR2	somatostatin receptor 2	0.024	Human
SELE	selectin E	0.024
PLEK	pleckstrin	0.023
POLH	polymerase (DNA directed), eta	0.023
LAMP3	lysosomal-associated membrane protein 3	0.023
CD83	CD83 molecule	0.022
STAT4	signal transducer and activator of transcription 4	0.022
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.022
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.022
MAPK10	mitogen-activated protein kinase 10	0.022
CXCR2	chemokine (C-X-C motif) receptor 2	0.022	Human
IGSF6	immunoglobulin superfamily, member 6	0.021
CH25H	cholesterol 25-hydroxylase	0.021
IDO1	indoleamine 2,3-dioxygenase 1	0.021
CD28	CD28 molecule	0.021
IL1R2	interleukin 1 receptor, type II	0.021
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.020
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.020
RNF11	ring finger protein 11	0.020
TBX21	T-box 21	0.020
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.020	Human
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.020
GZMK	granzyme K (granzyme 3; tryptase II)	0.019
CD86	CD86 molecule	0.019
ADAMDEC1	ADAM-like, decysin 1	0.018
ITK	IL2-inducible T-cell kinase	0.018
CXCR6	chemokine (C-X-C motif) receptor 6	0.018	Human
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.018
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.017
GNAS	GNAS complex locus	0.017
SLAMF1	signaling lymphocytic activation molecule family member 1	0.017
GPR6	G protein-coupled receptor 6	0.017
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.017	Human
CCL13	chemokine (C-C motif) ligand 13	0.017
IL6R	interleukin 6 receptor	0.017
TBC1D10A	TBC1 domain family, member 10A	0.016
GPR183	G protein-coupled receptor 183	0.016
S100A12	S100 calcium binding protein A12	0.016
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.016
CCL1	chemokine (C-C motif) ligand 1	0.016
IL1A	interleukin 1, alpha	0.016
GHRHR	growth hormone releasing hormone receptor	0.016
IL21R	interleukin 21 receptor	0.016
IL18R1	interleukin 18 receptor 1	0.015
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.014
CXCR1	chemokine (C-X-C motif) receptor 1	0.014	Human
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.014
GP5	glycoprotein V (platelet)	0.014
PNPLA2	patatin-like phospholipase domain containing 2	0.014
CORO7	coronin 7	0.014
GNLY	granulysin	0.014
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.014
ADRB1	adrenergic, beta-1-, receptor	0.014
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.014
C5AR1	complement component 5a receptor 1	0.014
PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	0.013
TFEC	transcription factor EC	0.013
ADRA1D	adrenergic, alpha-1D-, receptor	0.013
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.013
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.013
GPR65	G protein-coupled receptor 65	0.013
ICAM1	intercellular adhesion molecule 1	0.012
PRDX4	peroxiredoxin 4	0.012
PF4V1	platelet factor 4 variant 1	0.012	Human
PNOC	prepronociceptin	0.012
PDE1B	phosphodiesterase 1B, calmodulin-dependent	0.012
LEP	leptin	0.012
PI3	peptidase inhibitor 3, skin-derived	0.012
PDCD1	programmed cell death 1	0.011
CD2	CD2 molecule	0.011
CCKBR	cholecystokinin B receptor	0.011
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.011	Human
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.011
IER3	immediate early response 3	0.011
GPR109B	G protein-coupled receptor 109B	0.011
IL1F5	interleukin 1 family, member 5 (delta)	0.011
EZR	ezrin	0.011
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.011
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.011
CCR6	chemokine (C-C motif) receptor 6	0.011	Human
IL18RAP	interleukin 18 receptor accessory protein	0.011
CCR8	chemokine (C-C motif) receptor 8	0.011	Human
GHRL	ghrelin/obestatin prepropeptide	0.011
GNMT	glycine N-methyltransferase	0.011
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.011
GPRASP1	G protein-coupled receptor associated sorting protein 1	0.010
CRHR1	corticotropin releasing hormone receptor 1	0.010
PTX3	pentraxin 3, long	0.010
GIMAP4	GTPase, IMAP family member 4	0.010
LAG3	lymphocyte-activation gene 3	0.010
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.010