IMP

Process View

Homo sapiens

19 genes annotated in human

Multi-species View

positive regulation of mrna metabolic process

GO:1903313

Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of mrna metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of mrna metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
TOB1	transducer of ERBB2, 1	0.998
TNRC6A	trinucleotide repeat containing 6A	0.989	Human
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.981
DICER1	dicer 1, ribonuclease type III	0.967
EIF4A3	eukaryotic translation initiation factor 4A3	0.957	Mouse
BTG1	B-cell translocation gene 1, anti-proliferative	0.927	Human
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.852
SRRM1	serine/arginine repetitive matrix 1	0.812
PABPC1	poly(A) binding protein, cytoplasmic 1	0.794	Mouse
TNRC6C	trinucleotide repeat containing 6C	0.788
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.764
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.751
BTG2	BTG family, member 2	0.690
CNOT7	CCR4-NOT transcription complex, subunit 7	0.656
CNOT8	CCR4-NOT transcription complex, subunit 8	0.643	Human
EIF2C4	eukaryotic translation initiation factor 2C, 4	0.613
CPEB4	cytoplasmic polyadenylation element binding protein 4	0.507	Human
RNPS1	RNA binding protein S1, serine-rich domain	0.495
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.465
EIF2C3	eukaryotic translation initiation factor 2C, 3	0.426
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.407
SRPK1	SRSF protein kinase 1	0.367
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.348
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.309
TNRC6B	trinucleotide repeat containing 6B	0.269
PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	0.259
TCEA1	transcription elongation factor A (SII), 1	0.240
CNOT6	CCR4-NOT transcription complex, subunit 6	0.230
SF3B3	splicing factor 3b, subunit 3, 130kDa	0.212
JUNB	jun B proto-oncogene	0.184
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.171
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.148
IK	IK cytokine, down-regulator of HLA II	0.120
SF3B2	splicing factor 3b, subunit 2, 145kDa	0.101
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.098	Mouse
PNRC1	proline-rich nuclear receptor coactivator 1	0.094
GSPT1	G1 to S phase transition 1	0.085
USP10	ubiquitin specific peptidase 10	0.080
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.076
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.075
CPEB3	cytoplasmic polyadenylation element binding protein 3	0.070
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.068
IER2	immediate early response 2	0.064
SF1	splicing factor 1	0.061
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.059
CNOT1	CCR4-NOT transcription complex, subunit 1	0.057
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.055
PRKD2	protein kinase D2	0.052
DDX56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	0.051
SART1	squamous cell carcinoma antigen recognized by T cells	0.050
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.050
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.049
FUS	fused in sarcoma	0.048
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.046
CDK2	cyclin-dependent kinase 2	0.042
PCBP1	poly(rC) binding protein 1	0.040
PCBP2	poly(rC) binding protein 2	0.040
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.039
PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	0.038
HDAC7	histone deacetylase 7	0.038
JUND	jun D proto-oncogene	0.037
NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	0.035
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.035
RBM10	RNA binding motif protein 10	0.034
KLF6	Kruppel-like factor 6	0.034
RBM8A	RNA binding motif protein 8A	0.032
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.028
TOB2	transducer of ERBB2, 2	0.027
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.027
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.027
WDR61	WD repeat domain 61	0.027
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.026
SRPK2	SRSF protein kinase 2	0.025
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.024
CCNE1	cyclin E1	0.023
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.023
SOBP	sine oculis binding protein homolog (Drosophila)	0.022
PAIP2	poly(A) binding protein interacting protein 2	0.021
CSRNP1	cysteine-serine-rich nuclear protein 1	0.021
IPO8	importin 8	0.020
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.020
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.019
MFAP1	microfibrillar-associated protein 1	0.019
CLK2	CDC-like kinase 2	0.019
DUSP1	dual specificity phosphatase 1	0.018
PABPN1	poly(A) binding protein, nuclear 1	0.017
E2F1	E2F transcription factor 1	0.017
FOSL2	FOS-like antigen 2	0.017
BCAS2	breast carcinoma amplified sequence 2	0.017
CHTOP	chromatin target of PRMT1	0.017
AFF4	AF4/FMR2 family, member 4	0.017
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.016
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.016
ACIN1	apoptotic chromatin condensation inducer 1	0.015
HSPA4	heat shock 70kDa protein 4	0.015
CTNNBL1	catenin, beta like 1	0.015
CHERP	calcium homeostasis endoplasmic reticulum protein	0.015
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.015
KLF4	Kruppel-like factor 4 (gut)	0.015
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.014
SRSF7	serine/arginine-rich splicing factor 7	0.014
SRSF4	serine/arginine-rich splicing factor 4	0.014
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	0.014
EGR1	early growth response 1	0.014
EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	0.013
TRIM25	tripartite motif containing 25	0.013
SRSF6	serine/arginine-rich splicing factor 6	0.013
MBNL1	muscleblind-like (Drosophila)	0.013
DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B	0.013
MKNK1	MAP kinase interacting serine/threonine kinase 1	0.013
CPEB2	cytoplasmic polyadenylation element binding protein 2	0.012	Human
BCL6	B-cell CLL/lymphoma 6	0.012
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.012
POP5	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)	0.011
CCND2	cyclin D2	0.011
GADD45B	growth arrest and DNA-damage-inducible, beta	0.011
TIPARP	TCDD-inducible poly(ADP-ribose) polymerase	0.011
HSPH1	heat shock 105kDa/110kDa protein 1	0.011
SRRT	serrate RNA effector molecule homolog (Arabidopsis)	0.011
KPNB1	karyopherin (importin) beta 1	0.011
MKNK2	MAP kinase interacting serine/threonine kinase 2	0.011
YTHDC1	YTH domain containing 1	0.011
PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B	0.011
PABPC3	poly(A) binding protein, cytoplasmic 3	0.010
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.010
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.010
ATXN2	ataxin 2	0.010
ADAR	adenosine deaminase, RNA-specific	0.010
C17orf85	chromosome 17 open reading frame 85	0.010