IMP

Process View

Mus musculus

18 genes annotated in mouse

response to dietary excess

GO:0002021

The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to dietary excess"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to dietary excess" (in gray)

Name	Description	Probability	Func Analog Organism
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.880
Tgfbr2	transforming growth factor, beta receptor II	0.525	Mouse
Acvr1	activin A receptor, type 1	0.450	Mouse
Tgfbr1	transforming growth factor, beta receptor I	0.262	Mouse
Nodal	nodal	0.241	Mouse
Kiss1	KiSS-1 metastasis-suppressor	0.230
Smad3	MAD homolog 3 (Drosophila)	0.221
Gdf5	growth differentiation factor 5	0.179	Mouse
Esr1	estrogen receptor 1 (alpha)	0.112
Pnpla2	patatin-like phospholipase domain containing 2	0.106
Gcgr	glucagon receptor	0.093
Fgfr3	fibroblast growth factor receptor 3	0.089
Hand2	heart and neural crest derivatives expressed transcript 2	0.070
Shh	sonic hedgehog	0.069
Lepr	leptin receptor	0.069
Tgfb2	transforming growth factor, beta 2	0.063
Kl	klotho	0.063
Gdf3	growth differentiation factor 3	0.062
Nos3	nitric oxide synthase 3, endothelial cell	0.062
Hand1	heart and neural crest derivatives expressed transcript 1	0.058
Pparg	peroxisome proliferator activated receptor gamma	0.056
Tgfbr3	transforming growth factor, beta receptor III	0.054
Ar	androgen receptor	0.052
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.047	Mouse
Pgr	progesterone receptor	0.047
Apc	adenomatosis polyposis coli	0.044
Smad4	MAD homolog 4 (Drosophila)	0.043
Eng	endoglin	0.041
Fgf8	fibroblast growth factor 8	0.038
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.038
Esr2	estrogen receptor 2 (beta)	0.034
Adrb1	adrenergic receptor, beta 1	0.033
Sox9	SRY-box containing gene 9	0.033
Smo	smoothened homolog (Drosophila)	0.033
Alx4	aristaless-like homeobox 4	0.032
Gata4	GATA binding protein 4	0.032
Foxc1	forkhead box C1	0.032
Adrb2	adrenergic receptor, beta 2	0.032
ND6	NADH dehydrogenase subunit 6	0.032
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.031
Fgfr2	fibroblast growth factor receptor 2	0.030
Bptf	bromodomain PHD finger transcription factor	0.030
Fmn1	formin 1	0.028
Shc1	src homology 2 domain-containing transforming protein C1	0.028
Gdf6	growth differentiation factor 6	0.027	Mouse
Fshr	follicle stimulating hormone receptor	0.027
Ece1	endothelin converting enzyme 1	0.027
Ghr	growth hormone receptor	0.025
Cckbr	cholecystokinin B receptor	0.025
Foxh1	forkhead box H1	0.025
Cldn16	claudin 16	0.025
Bmp7	bone morphogenetic protein 7	0.024	Mouse
Oprm1	opioid receptor, mu 1	0.024
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.024
Chrd	chordin	0.023
Pten	phosphatase and tensin homolog	0.023
Bmper	BMP-binding endothelial regulator	0.022
Ptch1	patched homolog 1	0.022
Smad6	MAD homolog 6 (Drosophila)	0.022
Ednra	endothelin receptor type A	0.021
Vcl	vinculin	0.021
Lox	lysyl oxidase	0.021
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.021	Mouse
Apob	apolipoprotein B	0.021
Ldlr	low density lipoprotein receptor	0.020
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.020	Mouse
Sstr4	somatostatin receptor 4	0.020
Ncor1	nuclear receptor co-repressor 1	0.020
Grm2	glutamate receptor, metabotropic 2	0.020
Oprd1	opioid receptor, delta 1	0.019
Epas1	endothelial PAS domain protein 1	0.019
Prl4a1	prolactin family 4, subfamily a, member 1	0.019
Hbb-b1	hemoglobin, beta adult major chain	0.019
Nog	noggin	0.019
Fgfr1	fibroblast growth factor receptor 1	0.019
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.018
Vegfa	vascular endothelial growth factor A	0.018
Msn	moesin	0.018
Tdgf1	teratocarcinoma-derived growth factor 1	0.018
Prkg1	protein kinase, cGMP-dependent, type I	0.018
Zic3	zinc finger protein of the cerebellum 3	0.017
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.017
Mb	myoglobin	0.017
Gdf9	growth differentiation factor 9	0.017
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.017
Lhx6	LIM homeobox protein 6	0.016
Nhlh2	nescient helix loop helix 2	0.016
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.016
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.016
Bmp2	bone morphogenetic protein 2	0.015	Mouse
Edn3	endothelin 3	0.015
Clcnka	chloride channel Ka	0.015
Hba-a1	hemoglobin alpha, adult chain 1	0.015
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.015
Cer1	cerberus 1 homolog (Xenopus laevis)	0.015
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.015
Bmp5	bone morphogenetic protein 5	0.015	Mouse
Gata6	GATA binding protein 6	0.014
Adora3	adenosine A3 receptor	0.014
Itga8	integrin alpha 8	0.014
Msx1	homeobox, msh-like 1	0.014
Cfc1	cripto, FRL-1, cryptic family 1	0.014
Hrh1	histamine receptor H1	0.014
Gpr27	G protein-coupled receptor 27	0.014
Gdf1	growth differentiation factor 1	0.014	Mouse
Sycn	syncollin	0.014
Kiss1r	KISS1 receptor	0.013
Rxra	retinoid X receptor alpha	0.013
Fbn1	fibrillin 1	0.013
Hoxd13	homeobox D13	0.013
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.013
Gast	gastrin	0.013
Nptx2	neuronal pentraxin 2	0.013
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.013
Jag1	jagged 1	0.013
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.013
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.013	Mouse
Sst	somatostatin	0.012
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.012
Gjb1	gap junction protein, beta 1	0.012
Adrb3	adrenergic receptor, beta 3	0.012
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.012
Oprk1	opioid receptor, kappa 1	0.012
Npy2r	neuropeptide Y receptor Y2	0.012
Nf1	neurofibromatosis 1	0.012
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.012
Fshb	follicle stimulating hormone beta	0.012
Sstr1	somatostatin receptor 1	0.012
Nos1	nitric oxide synthase 1, neuronal	0.012
Crhr1	corticotropin releasing hormone receptor 1	0.011
Acvr2a	activin receptor IIA	0.011
Cdh5	cadherin 5	0.011
Abhd5	abhydrolase domain containing 5	0.011
Kif3a	kinesin family member 3A	0.011
Palm3	paralemmin 3	0.011
Cdh6	cadherin 6	0.011
Smad7	MAD homolog 7 (Drosophila)	0.011
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.011
Edn1	endothelin 1	0.011
Smad2	MAD homolog 2 (Drosophila)	0.011
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.011
Crhr2	corticotropin releasing hormone receptor 2	0.011
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.010	Mouse
Trhr2	thyrotropin releasing hormone receptor 2	0.010
Cpd	carboxypeptidase D	0.010
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.010
Cav1	caveolin 1, caveolae protein	0.010
Foxf2	forkhead box F2	0.010
Npc1	Niemann Pick type C1	0.010
Abp1	amiloride binding protein 1 (amine oxidase, copper-containing)	0.010
Ext1	exostoses (multiple) 1	0.010
Hnf4a	hepatic nuclear factor 4, alpha	0.010