IMP

Process View

Mus musculus

2 genes annotated in mouse

regulation of double strand break repair via homologous recombination

Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of double strand break repair via homologous recombination"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of double strand break repair via homologous recombination" (in gray)

Name	Description	Probability	Func Analog Organism
Ccna2	cyclin A2	0.764
Rrm2	ribonucleotide reductase M2	0.481
Cdk4	cyclin-dependent kinase 4	0.458
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.388
Ect2	ect2 oncogene	0.269
Ckap2	cytoskeleton associated protein 2	0.174
Ccnb1	cyclin B1	0.142
Ccne1	cyclin E1	0.115
Ccnb2	cyclin B2	0.108
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.091
Polh	polymerase (DNA directed), eta (RAD 30 related)	0.081
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.077
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.075
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.067
Brca2	breast cancer 2	0.057
Cdca8	cell division cycle associated 8	0.052
Ttk	Ttk protein kinase	0.050
Ccdc99	coiled-coil domain containing 99	0.049
Polk	polymerase (DNA directed), kappa	0.047
Cdk2	cyclin-dependent kinase 2	0.045	Yeast
Prc1	protein regulator of cytokinesis 1	0.043
Brca1	breast cancer 1	0.043
Cenpn	centromere protein N	0.043
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.039
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.039
Cks2	CDC28 protein kinase regulatory subunit 2	0.037
Plk4	polo-like kinase 4 (Drosophila)	0.035
Pbk	PDZ binding kinase	0.035
Rad51ap1	RAD51 associated protein 1	0.034	Human
Wdhd1	WD repeat and HMG-box DNA binding protein 1	0.033
Poli	polymerase (DNA directed), iota	0.032
Ncaph	non-SMC condensin I complex, subunit H	0.032
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.031
Cdca5	cell division cycle associated 5	0.029
Rfc3	replication factor C (activator 1) 3	0.028
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.027
Birc5	baculoviral IAP repeat-containing 5	0.026
Ube2c	ubiquitin-conjugating enzyme E2C	0.025
Refbp2	RNA and export factor binding protein 2	0.024
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.024
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.022
Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.022
Stil	Scl/Tal1 interrupting locus	0.022
Fbl	fibrillarin	0.022
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.022
Blm	Bloom syndrome, RecQ helicase-like	0.022
Ncapg2	non-SMC condensin II complex, subunit G2	0.022
Plk1	polo-like kinase 1 (Drosophila)	0.021
Cdkn3	cyclin-dependent kinase inhibitor 3	0.021
Racgap1	Rac GTPase-activating protein 1	0.021
Melk	maternal embryonic leucine zipper kinase	0.019
Lrr1	leucine rich repeat protein 1	0.019
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.019
Cenpk	centromere protein K	0.019
Cenpa	centromere protein A	0.018
Aurkb	aurora kinase B	0.018
Kif22	kinesin family member 22	0.018
Cdc45	cell division cycle 45 homolog (S. cerevisiae)	0.017
Kif11	kinesin family member 11	0.016
Kif2c	kinesin family member 2C	0.016
Kif20a	kinesin family member 20A	0.016
Rrm1	ribonucleotide reductase M1	0.015
BC055324	cDNA sequence BC055324	0.015
Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.015
Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	0.015
Lin9	lin-9 homolog (C. elegans)	0.015
Chek1	checkpoint kinase 1 homolog (S. pombe)	0.015	Human
Cenph	centromere protein H	0.015
Mnd1	meiotic nuclear divisions 1 homolog (S. cerevisiae)	0.015
Thoc4	THO complex 4	0.014
Siah1b	seven in absentia 1B	0.014
Snrpb	small nuclear ribonucleoprotein B	0.014
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.013
Pole3	polymerase (DNA directed), epsilon 3 (p17 subunit)	0.013
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.013
Hist1h1a	histone cluster 1, H1a	0.012
Mis18bp1	MIS18 binding protein 1	0.012
Orc1	origin recognition complex, subunit 1	0.012
Rad51	RAD51 homolog (S. cerevisiae)	0.012	Human Fly
Zc3hc1	zinc finger, C3HC type 1	0.012
Cenpp	centromere protein P	0.012
Zwilch	Zwilch, kinetochore associated, homolog (Drosophila)	0.012
H2afx	H2A histone family, member X	0.012
Rfc5	replication factor C (activator 1) 5	0.011
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.011
Pcna	proliferating cell nuclear antigen	0.011
Kif4	kinesin family member 4	0.011
Cdc23	CDC23 (cell division cycle 23, yeast, homolog)	0.011
Cdt1	chromatin licensing and DNA replication factor 1	0.011
Aurka	aurora kinase A	0.011
Chek2	CHK2 checkpoint homolog (S. pombe)	0.011
Ccne2	cyclin E2	0.010
Dtl	denticleless homolog (Drosophila)	0.010
Mki67	antigen identified by monoclonal antibody Ki 67	0.010
E2f8	E2F transcription factor 8	0.010
Ercc6l	excision repair cross-complementing rodent repair deficiency complementation group 6 - like	0.010
Tfrc	transferrin receptor	0.010