IMP

Process View

Mus musculus

1 genes annotated in mouse

response to histamine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to histamine"

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Name	Description	Probability	Func Analog Organism
Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2	0.998	Mouse
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.982	Human Mouse
Grid1	glutamate receptor, ionotropic, delta 1	0.956
Gabra5	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5	0.908	Mouse
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.790	Mouse Rat
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.728
B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.592
Pgr	progesterone receptor	0.584
Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2	0.550
Gad2	glutamic acid decarboxylase 2	0.542
Nxph1	neurexophilin 1	0.515
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	0.457
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.378
Cnr1	cannabinoid receptor 1 (brain)	0.269
Rit2	Ras-like without CAAX 2	0.265
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.184
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.178
Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1	0.153
Cdh8	cadherin 8	0.137
Cdh9	cadherin 9	0.117
Thrb	thyroid hormone receptor beta	0.116
Grm8	glutamate receptor, metabotropic 8	0.107
Npy2r	neuropeptide Y receptor Y2	0.104
Gabra2	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2	0.104	Mouse
Slc12a5	solute carrier family 12, member 5	0.101
Cntn4	contactin 4	0.101
En2	engrailed 2	0.093
Dync1i1	dynein cytoplasmic 1 intermediate chain 1	0.086
Slc1a6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.083
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.082
Gabrb1	gamma-aminobutyric acid (GABA) A receptor, subunit beta 1	0.076	Rat
Cdh10	cadherin 10	0.075
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.071
Adcyap1	adenylate cyclase activating polypeptide 1	0.062
Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.061
Oprk1	opioid receptor, kappa 1	0.060
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.059
Calb1	calbindin 1	0.059
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.059
Krt12	keratin 12	0.054
Gsbs	G substrate	0.053
Neto1	neuropilin (NRP) and tolloid (TLL)-like 1	0.052
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.050
Trhr	thyrotropin releasing hormone receptor	0.050
Upp2	uridine phosphorylase 2	0.049
Scn1a	sodium channel, voltage-gated, type I, alpha	0.049
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.048
Slc4a7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	0.048
Chic1	cysteine-rich hydrophobic domain 1	0.046
Nrsn1	neurensin 1	0.046
Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.045
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.044
Pcdh10	protocadherin 10	0.043
Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1	0.043
Htr1a	5-hydroxytryptamine (serotonin) receptor 1A	0.043
Col19a1	collagen, type XIX, alpha 1	0.041
Cntn1	contactin 1	0.040
Cga	glycoprotein hormones, alpha subunit	0.040
Grid2	glutamate receptor, ionotropic, delta 2	0.040
Braf	Braf transforming gene	0.040
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.040
Slitrk6	SLIT and NTRK-like family, member 6	0.040
Tac2	tachykinin 2	0.038
Epha5	Eph receptor A5	0.037
Adra2c	adrenergic receptor, alpha 2c	0.037
Mmp16	matrix metallopeptidase 16	0.036
Syt1	synaptotagmin I	0.035
Gad1	glutamic acid decarboxylase 1	0.035
Hcrt	hypocretin	0.035
Il3	interleukin 3	0.034
Cntn3	contactin 3	0.034
Fam84a	family with sequence similarity 84, member A	0.034
Oprm1	opioid receptor, mu 1	0.034
Odz1	odd Oz/ten-m homolog 1 (Drosophila)	0.034
Plcb1	phospholipase C, beta 1	0.034
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.033
Kif5c	kinesin family member 5C	0.033
Syn2	synapsin II	0.033
Vsnl1	visinin-like 1	0.033
Aqp4	aquaporin 4	0.032
Gabra3	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3	0.032	Mouse
Mid1	midline 1	0.032
Opn1mw	opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)	0.032
Rcvrn	recoverin	0.031
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	0.029
Cacng3	calcium channel, voltage-dependent, gamma subunit 3	0.029
Dcc	deleted in colorectal carcinoma	0.029
Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform	0.029
Cacnb2	calcium channel, voltage-dependent, beta 2 subunit	0.028
Calb2	calbindin 2	0.028
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.028
Nxph2	neurexophilin 2	0.028
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.028
Nap1l2	nucleosome assembly protein 1-like 2	0.027
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.027
Agtr2	angiotensin II receptor, type 2	0.027
Gabra6	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6	0.027	Mouse
Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	0.027
Sh3gl2	SH3-domain GRB2-like 2	0.027
Mgat4c	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)	0.027
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.026
Mc1r	melanocortin 1 receptor	0.026
Baiap2	brain-specific angiogenesis inhibitor 1-associated protein 2	0.026
Mobp	myelin-associated oligodendrocytic basic protein	0.026
Camk4	calcium/calmodulin-dependent protein kinase IV	0.025
Gpr12	G-protein coupled receptor 12	0.025
Fgf14	fibroblast growth factor 14	0.025
Cadps	Ca2+-dependent secretion activator	0.025
Chrna6	cholinergic receptor, nicotinic, alpha polypeptide 6	0.025
Fgf12	fibroblast growth factor 12	0.025
Cckbr	cholecystokinin B receptor	0.025
Psg16	pregnancy specific glycoprotein 16	0.025
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.025
Ntng1	netrin G1	0.025
En1	engrailed 1	0.024
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.024
Psg17	pregnancy specific glycoprotein 17	0.024
Olfr49	olfactory receptor 49	0.023
Rorb	RAR-related orphan receptor beta	0.023
Pclo	piccolo (presynaptic cytomatrix protein)	0.023
Fshb	follicle stimulating hormone beta	0.023
6330527O06Rik	RIKEN cDNA 6330527O06 gene	0.023
Npas1	neuronal PAS domain protein 1	0.023
Cntn2	contactin 2	0.023
Msx2	homeobox, msh-like 2	0.022
Gucy2e	guanylate cyclase 2e	0.022
Rgs7	regulator of G protein signaling 7	0.022
Glrb	glycine receptor, beta subunit	0.022	Mouse
Gjd2	gap junction protein, delta 2	0.022
Gabrr2	gamma-aminobutyric acid (GABA) C receptor, subunit rho 2	0.022
Adarb2	adenosine deaminase, RNA-specific, B2	0.022
Dio2	deiodinase, iodothyronine, type II	0.021
Csf3	colony stimulating factor 3 (granulocyte)	0.021
Plp1	proteolipid protein (myelin) 1	0.021
Arl10	ADP-ribosylation factor-like 10	0.021
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.021
Gnat1	guanine nucleotide binding protein, alpha transducing 1	0.021
Epha6	Eph receptor A6	0.021
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.021
Nobox	NOBOX oogenesis homeobox	0.021
Sebox	SEBOX homeobox	0.020
Ptprr	protein tyrosine phosphatase, receptor type, R	0.020
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.020
Gabrr1	gamma-aminobutyric acid (GABA) C receptor, subunit rho 1	0.020	Mouse
Vstm2a	V-set and transmembrane domain containing 2A	0.020
Neurod1	neurogenic differentiation 1	0.020
Olfm3	olfactomedin 3	0.020
Rfpl4	ret finger protein-like 4	0.020
Zfhx4	zinc finger homeodomain 4	0.019
BC051019	cDNA sequence BC051019	0.019
Scrg1	scrapie responsive gene 1	0.019
Sncb	synuclein, beta	0.019
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.019
Prox1	prospero-related homeobox 1	0.019
Folh1	folate hydrolase	0.019
Mtap1b	microtubule-associated protein 1B	0.019
Dcx	doublecortin	0.019
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.018
Mageb3	melanoma antigen, family B, 3	0.018
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.018
Adcy8	adenylate cyclase 8	0.018
Scg2	secretogranin II	0.018
Ncam2	neural cell adhesion molecule 2	0.018
Doc2b	double C2, beta	0.018
Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.018
Kcnk4	potassium channel, subfamily K, member 4	0.018
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.017
Caln1	calneuron 1	0.017
Slc18a3	solute carrier family 18 (vesicular monoamine), member 3	0.017
Gdap1	ganglioside-induced differentiation-associated-protein 1	0.017
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.017
Oprl1	opioid receptor-like 1	0.017
Trap1a	tumor rejection antigen P1A	0.017
Ankrd43	ankyrin repeat domain 43	0.017
Clgn	calmegin	0.017
Neurod2	neurogenic differentiation 2	0.017
Slitrk4	SLIT and NTRK-like family, member 4	0.017
Drd1a	dopamine receptor D1A	0.016
Ccnb3	cyclin B3	0.016
B3galt2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	0.016
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.016
Cplx3	complexin 3	0.016
Scn8a	sodium channel, voltage-gated, type VIII, alpha	0.016
Adam3	a disintegrin and metallopeptidase domain 3 (cyritestin)	0.016
Rgs8	regulator of G-protein signaling 8	0.016
Hes2	hairy and enhancer of split 2 (Drosophila)	0.016
Hoxd12	homeobox D12	0.016
1810030J14Rik	RIKEN cDNA 1810030J14 gene	0.016
Svs4	seminal vesicle secretory protein 4	0.016
Znrf4	zinc and ring finger 4	0.016
Kcna4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.015
Prl	prolactin	0.015
BC018465	cDNA sequence BC018465	0.015
Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)	0.015
Rasgrp1	RAS guanyl releasing protein 1	0.015
Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1	0.015
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.015
Serpinb11	serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11	0.015
Iqgap1	IQ motif containing GTPase activating protein 1	0.015
Scgb3a1	secretoglobin, family 3A, member 1	0.015
Wnt7a	wingless-related MMTV integration site 7A	0.015
Tll1	tolloid-like	0.015
Ids	iduronate 2-sulfatase	0.015
Klhl1	kelch-like 1 (Drosophila)	0.015
Agrp	agouti related protein	0.015
Insm2	insulinoma-associated 2	0.015
Csn1s1	casein alpha s1	0.015
Trpc5	transient receptor potential cation channel, subfamily C, member 5	0.015
Krtap8-1	keratin associated protein 8-1	0.014
Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3	0.014
Myt1	myelin transcription factor 1	0.014
Ppef2	protein phosphatase, EF hand calcium-binding domain 2	0.014
D3Bwg0562e	DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed	0.014
Rgs6	regulator of G-protein signaling 6	0.014
Rho	rhodopsin	0.014
Cbln3	cerebellin 3 precursor protein	0.014
Slc6a15	solute carrier family 6 (neurotransmitter transporter), member 15	0.014
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.014
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.014
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.014
Nefh	neurofilament, heavy polypeptide	0.014
Smpd3	sphingomyelin phosphodiesterase 3, neutral	0.014
Htr5b	5-hydroxytryptamine (serotonin) receptor 5B	0.014
Rs1	retinoschisis (X-linked, juvenile) 1 (human)	0.014
Hrk	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.014
Neurod6	neurogenic differentiation 6	0.014
Slc6a2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.014
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.014
Il1rapl1	interleukin 1 receptor accessory protein-like 1	0.014
Gpr143	G protein-coupled receptor 143	0.014
Fosb	FBJ osteosarcoma oncogene B	0.014
Krtap14	keratin associated protein 14	0.014
Mapk10	mitogen-activated protein kinase 10	0.014
Retnlb	resistin like beta	0.014
Mtmr7	myotubularin related protein 7	0.014
Rgs4	regulator of G-protein signaling 4	0.014
C78859	expressed sequence C78859	0.013
Krt86	keratin 86	0.013
Epx	eosinophil peroxidase	0.013
Kif3b	kinesin family member 3B	0.013
Pak3	p21 protein (Cdc42/Rac)-activated kinase 3	0.013
Lhx3	LIM homeobox protein 3	0.013
Csn1s2b	casein alpha s2-like B	0.013
Gpr50	G-protein-coupled receptor 50	0.013
Tbr1	T-box brain gene 1	0.013
Dsc3	desmocollin 3	0.013
Cplx4	complexin 4	0.013
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.013
Cck	cholecystokinin	0.013
Npy6r	neuropeptide Y receptor Y6	0.013
Tyrp1	tyrosinase-related protein 1	0.013
Nefl	neurofilament, light polypeptide	0.013
Arr3	arrestin 3, retinal	0.013
Ntm	neurotrimin	0.013
Klk6	kallikrein related-peptidase 6	0.013
2610034M16Rik	RIKEN cDNA 2610034M16 gene	0.012
Cer1	cerberus 1 homolog (Xenopus laevis)	0.012
Bmp15	bone morphogenetic protein 15	0.012
Mas1	MAS1 oncogene	0.012
Epb4.1l4b	erythrocyte protein band 4.1-like 4b	0.012
Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	0.012
Spdef	SAM pointed domain containing ets transcription factor	0.012
Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.012
Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1	0.012
Clip1	CAP-GLY domain containing linker protein 1	0.012
Sprr2k	small proline-rich protein 2K	0.012
Usp29	ubiquitin specific peptidase 29	0.012
Vip	vasoactive intestinal polypeptide	0.012
Sva	seminal vesicle antigen	0.012
Nrg3	neuregulin 3	0.012
Gja5	gap junction protein, alpha 5	0.012
Capza3	capping protein (actin filament) muscle Z-line, alpha 3	0.012
Cntnap2	contactin associated protein-like 2	0.012
Cnga2	cyclic nucleotide gated channel alpha 2	0.012
Prl4a1	prolactin family 4, subfamily a, member 1	0.012
Slc4a5	solute carrier family 4, sodium bicarbonate cotransporter, member 5	0.012
Gfap	glial fibrillary acidic protein	0.012
Kif5a	kinesin family member 5A	0.012
Gpr45	G protein-coupled receptor 45	0.012
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.011
Gabra4	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4	0.011	Mouse
Apod	apolipoprotein D	0.011
Dgkb	diacylglycerol kinase, beta	0.011
Lgr5	leucine rich repeat containing G protein coupled receptor 5	0.011
Cadm2	cell adhesion molecule 2	0.011
Bsn	bassoon	0.011
Ryr3	ryanodine receptor 3	0.011
Grin2c	glutamate receptor, ionotropic, NMDA2C (epsilon 3)	0.011
Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	0.011
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3	0.011	Mouse
Tac1	tachykinin 1	0.011
Ugt8a	UDP galactosyltransferase 8A	0.011
Shc3	src homology 2 domain-containing transforming protein C3	0.011
Lrrtm2	leucine rich repeat transmembrane neuronal 2	0.011
Fgf13	fibroblast growth factor 13	0.011
Neurog2	neurogenin 2	0.011
Resp18	regulated endocrine-specific protein 18	0.011
Glra4	glycine receptor, alpha 4 subunit	0.011
Bcl2l10	Bcl2-like 10	0.011
Esr1	estrogen receptor 1 (alpha)	0.011
Cntnap1	contactin associated protein-like 1	0.011
Glra2	glycine receptor, alpha 2 subunit	0.011	Mouse
AI118078	expressed sequence AI118078	0.011
Rnf112	ring finger protein 112	0.011
Olfr155	olfactory receptor 155	0.011
Ndp	Norrie disease (pseudoglioma) (human)	0.011
Sag	retinal S-antigen	0.011
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.011
Prss32	protease, serine, 32	0.011
Fstl5	follistatin-like 5	0.011
Rrh	retinal pigment epithelium derived rhodopsin homolog	0.011
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.011
Glra1	glycine receptor, alpha 1 subunit	0.011	Mouse
Kcnip4	Kv channel interacting protein 4	0.011
Abcc8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.010
Enam	enamelin	0.010
Car5a	carbonic anhydrase 5a, mitochondrial	0.010
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.010
Tshr	thyroid stimulating hormone receptor	0.010
Lrrc6	leucine rich repeat containing 6 (testis)	0.010
Bche	butyrylcholinesterase	0.010
Prl8a6	prolactin family 8, subfamily a, member 6	0.010
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.010
Spam1	sperm adhesion molecule 1	0.010
Dixdc1	DIX domain containing 1	0.010
Pcdh20	protocadherin 20	0.010
Ambn	ameloblastin	0.010
Hbb-bh1	hemoglobin Z, beta-like embryonic chain	0.010
Lrrc4c	leucine rich repeat containing 4C	0.010
Syt2	synaptotagmin II	0.010
4922501L14Rik	RIKEN cDNA 4922501L14 gene	0.010
Crygn	crystallin, gamma N	0.010