IMP

Process View

Mus musculus

23 genes annotated in mouse

Multi-species View

peptidyl tyrosine dephosphorylation

GO:0035335

The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "peptidyl tyrosine dephosphorylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "peptidyl tyrosine dephosphorylation" (in gray)

Name	Description	Probability	Func Analog Organism
Fyn	Fyn proto-oncogene	0.537
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.471	Fly
Ush1c	Usher syndrome 1C homolog (human)	0.165
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.148
Igh	immunoglobulin heavy chain complex	0.139
Vav1	vav 1 oncogene	0.093
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.065
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.061
Mapk1	mitogen-activated protein kinase 1	0.060
Prkcd	protein kinase C, delta	0.058
Ptprf	protein tyrosine phosphatase, receptor type, F	0.055	Human Mouse Rat Fly
Cdh5	cadherin 5	0.052
Sykb	spleen tyrosine kinase	0.048
Pstpip2	proline-serine-threonine phosphatase-interacting protein 2	0.047
Ikzf1	IKAROS family zinc finger 1	0.044
Sharpin	SHANK-associated RH domain interacting protein	0.037
Jak1	Janus kinase 1	0.036
Plcg2	phospholipase C, gamma 2	0.035
Cdc25b	cell division cycle 25 homolog B (S. pombe)	0.035	Fly
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.035
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.035
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.034
Grb2	growth factor receptor bound protein 2	0.031
Nsf	N-ethylmaleimide sensitive fusion protein	0.030
Flt1	FMS-like tyrosine kinase 1	0.030
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.030	Human Mouse
Il1rapl1	interleukin 1 receptor accessory protein-like 1	0.028
Tcrb	T-cell receptor beta chain	0.028
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.028
Myo6	myosin VI	0.027
Grxcr1	glutaredoxin, cysteine rich 1	0.026
Plk1	polo-like kinase 1 (Drosophila)	0.026
Shc1	src homology 2 domain-containing transforming protein C1	0.026
Cdc25a	cell division cycle 25 homolog A (S. pombe)	0.025	Fly
Inpp5d	inositol polyphosphate-5-phosphatase D	0.025
Ptprn	protein tyrosine phosphatase, receptor type, N	0.025
Chl1	cell adhesion molecule with homology to L1CAM	0.023
Map2k2	mitogen-activated protein kinase kinase 2	0.022	Mouse
Cd22	CD22 antigen	0.022
Src	Rous sarcoma oncogene	0.022
Foxc1	forkhead box C1	0.021
Amotl2	angiomotin-like 2	0.021
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.021
Ctnnb1	catenin (cadherin associated protein), beta 1	0.021
Tcrd	T-cell receptor delta chain	0.021
Rap1b	RAS related protein 1b	0.020
LOC100503041	PDZ domain-containing protein 7-like	0.019
Kit	kit oncogene	0.018
Ptprs	protein tyrosine phosphatase, receptor type, S	0.018	Mouse Fly
Plxna1	plexin A1	0.018
Itga3	integrin alpha 3	0.017
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.017
Efnb2	ephrin B2	0.017
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.017
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.017
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.017
Homer1	homer homolog 1 (Drosophila)	0.017
Cd72	CD72 antigen	0.017
Rps6ka3	ribosomal protein S6 kinase polypeptide 3	0.017
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.017
Cdh2	cadherin 2	0.016
Ifrd1	interferon-related developmental regulator 1	0.016
Jak2	Janus kinase 2	0.016
Fgfr2	fibroblast growth factor receptor 2	0.016
Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.016
Efnb1	ephrin B1	0.016
Pcdh15	protocadherin 15	0.016
Cd19	CD19 antigen	0.016
Prkcb	protein kinase C, beta	0.015
Grm1	glutamate receptor, metabotropic 1	0.015
Kdr	kinase insert domain protein receptor	0.015
Pag1	phosphoprotein associated with glycosphingolipid microdomains 1	0.015
Traf3ip2	TRAF3 interacting protein 2	0.015
Cntn6	contactin 6	0.015
Actn1	actinin, alpha 1	0.015
Rgs12	regulator of G-protein signaling 12	0.015
Cit	citron	0.015
Grid2	glutamate receptor, ionotropic, delta 2	0.014
Ptprm	protein tyrosine phosphatase, receptor type, M	0.014	Human Mouse
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.014
Wwc2	WW, C2 and coiled-coil domain containing 2	0.014
Bdnf	brain derived neurotrophic factor	0.014
Cd79b	CD79B antigen	0.014
Irf8	interferon regulatory factor 8	0.014
Kif4	kinesin family member 4	0.014
Ctnnd1	catenin (cadherin associated protein), delta 1	0.013
Fam64a	family with sequence similarity 64, member A	0.013
Dlx2	distal-less homeobox 2	0.013
Ptpn21	protein tyrosine phosphatase, non-receptor type 21	0.013	Mouse Rat
Dsg1a	desmoglein 1 alpha	0.013
Rgnef	Rho-guanine nucleotide exchange factor	0.012
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.012
Shank2	SH3/ankyrin domain gene 2	0.012
Fermt2	fermitin family homolog 2 (Drosophila)	0.012
Hras1	Harvey rat sarcoma virus oncogene 1	0.012
Gata3	GATA binding protein 3	0.012
Dlg2	discs, large homolog 2 (Drosophila)	0.012
Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.012
Rora	RAR-related orphan receptor alpha	0.012
Sh3rf1	SH3 domain containing ring finger 1	0.012
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.012
Fas	Fas (TNF receptor superfamily member 6)	0.012
Vav2	vav 2 oncogene	0.012
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.012
Trip6	thyroid hormone receptor interactor 6	0.012
Apbb2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.012
Nf1	neurofibromatosis 1	0.012
Mid2	midline 2	0.011
Ptprg	protein tyrosine phosphatase, receptor type, G	0.011	Human Mouse
Blnk	B-cell linker	0.011
Fmo1	flavin containing monooxygenase 1	0.011
Samd4b	sterile alpha motif domain containing 4B	0.011
Nrbp2	nuclear receptor binding protein 2	0.011
Klf7	Kruppel-like factor 7 (ubiquitous)	0.011
Sos1	son of sevenless homolog 1 (Drosophila)	0.011
Spred1	sprouty protein with EVH-1 domain 1, related sequence	0.011
Nfib	nuclear factor I/B	0.011
Zfhx3	zinc finger homeobox 3	0.011
Limch1	LIM and calponin homology domains 1	0.011
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.011
Rap2c	RAP2C, member of RAS oncogene family	0.011
Was	Wiskott-Aldrich syndrome homolog (human)	0.011
Cdc42se1	CDC42 small effector 1	0.011
Prkce	protein kinase C, epsilon	0.011
Tek	endothelial-specific receptor tyrosine kinase	0.011
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.010
Gmip	Gem-interacting protein	0.010
Klc2	kinesin light chain 2	0.010
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.010
Esr1	estrogen receptor 1 (alpha)	0.010
Pitx2	paired-like homeodomain transcription factor 2	0.010
Ccnb2	cyclin B2	0.010
Lair1	leukocyte-associated Ig-like receptor 1	0.010
Adcy2	adenylate cyclase 2	0.010
Prkd1	protein kinase D1	0.010