IMP

Process View

Mus musculus

14 genes annotated in mouse

response to ischemia

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to ischemia"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to ischemia" (in gray)

Name	Description	Probability	Func Analog Organism
Per2	period homolog 2 (Drosophila)	1.000
Cry2	cryptochrome 2 (photolyase-like)	1.000
Trp53	transformation related protein 53	1.000
Per1	period homolog 1 (Drosophila)	0.999	Mouse
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.999
Clock	circadian locomotor output cycles kaput	0.987
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.983
Neurl1a	neuralized homolog 1A (Drosophila)	0.981
Bax	BCL2-associated X protein	0.960	Mouse
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.844
Cry1	cryptochrome 1 (photolyase-like)	0.735
Pten	phosphatase and tensin homolog	0.712
Usp2	ubiquitin specific peptidase 2	0.597
Bak1	BCL2-antagonist/killer 1	0.445	Mouse
Mtap2	microtubule-associated protein 2	0.445
Ptrf	polymerase I and transcript release factor	0.428
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.382
Lpin1	lipin 1	0.333
Dlg4	discs, large homolog 4 (Drosophila)	0.323
Bcl2	B-cell leukemia/lymphoma 2	0.316
Tef	thyrotroph embryonic factor	0.278
Stim2	stromal interaction molecule 2	0.201
Pparg	peroxisome proliferator activated receptor gamma	0.190
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.187	Mouse
Actn2	actinin alpha 2	0.176
Kl	klotho	0.175
Cpeb3	cytoplasmic polyadenylation element binding protein 3	0.175	Mouse
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.172
Btrc	beta-transducin repeat containing protein	0.171
Slc34a3	solute carrier family 34 (sodium phosphate), member 3	0.168
Ghr	growth hormone receptor	0.154
Fgf23	fibroblast growth factor 23	0.144
Ncoa3	nuclear receptor coactivator 3	0.110
Fam20c	family with sequence similarity 20, member C	0.104
Emx1	empty spiracles homolog 1 (Drosophila)	0.101
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.091
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.091
Dmd	dystrophin, muscular dystrophy	0.087
Vdr	vitamin D receptor	0.082
Ptk2	PTK2 protein tyrosine kinase 2	0.076
Dusp1	dual specificity phosphatase 1	0.071
Rnf11	ring finger protein 11	0.071
Bcl2l1	BCL2-like 1	0.070	Mouse
Flot2	flotillin 2	0.063
Srpk3	serine/arginine-rich protein specific kinase 3	0.060
Dnm1	dynamin 1	0.060
Lmna	lamin A	0.059
Adcy9	adenylate cyclase 9	0.054
Csnk1e	casein kinase 1, epsilon	0.052
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.049
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.049
Ar	androgen receptor	0.048
Dsg1a	desmoglein 1 alpha	0.046
Cpeb2	cytoplasmic polyadenylation element binding protein 2	0.046	Mouse
Pxn	paxillin	0.046
Cpeb4	cytoplasmic polyadenylation element binding protein 4	0.046
Snta1	syntrophin, acidic 1	0.044
Kif1b	kinesin family member 1B	0.043
Sgca	sarcoglycan, alpha (dystrophin-associated glycoprotein)	0.043
Mfn2	mitofusin 2	0.041
Mapkapk2	MAP kinase-activated protein kinase 2	0.039
Klf6	Kruppel-like factor 6	0.038
Bhlhe40	basic helix-loop-helix family, member e40	0.037
Vhl	von Hippel-Lindau tumor suppressor	0.037
Skil	SKI-like	0.036
Tob1	transducer of ErbB-2.1	0.035
Prkce	protein kinase C, epsilon	0.034
Dbp	D site albumin promoter binding protein	0.031
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.030
Rora	RAR-related orphan receptor alpha	0.029
Huwe1	HECT, UBA and WWE domain containing 1	0.029
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.029
Per3	period homolog 3 (Drosophila)	0.028	Mouse
Dnajb9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.028
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.027
Mtor	mechanistic target of rapamycin (serine/threonine kinase)	0.027
Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.027
Klf9	Kruppel-like factor 9	0.026
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.026
Lrp1	low density lipoprotein receptor-related protein 1	0.026
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.026
Pmm1	phosphomannomutase 1	0.025
Flii	flightless I homolog (Drosophila)	0.025
Rab3a	RAB3A, member RAS oncogene family	0.025
Homer1	homer homolog 1 (Drosophila)	0.025
Mapk14	mitogen-activated protein kinase 14	0.024
App	amyloid beta (A4) precursor protein	0.024
Flot1	flotillin 1	0.024
Map2k2	mitogen-activated protein kinase kinase 2	0.023
Col1a1	collagen, type I, alpha 1	0.023
Wbp2	WW domain binding protein 2	0.023
Arc	activity regulated cytoskeletal-associated protein	0.022
Zfand5	zinc finger, AN1-type domain 5	0.021
Rxra	retinoid X receptor alpha	0.021
Prnp	prion protein	0.021
Mapk12	mitogen-activated protein kinase 12	0.021
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.020
Lepr	leptin receptor	0.020
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.020
Mdm2	transformed mouse 3T3 cell double minute 2	0.019
Adcy1	adenylate cyclase 1	0.019
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.019
Ubc	ubiquitin C	0.019
Agpat1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	0.019
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.019
Ubap1	ubiquitin-associated protein 1	0.019
Bbc3	BCL2 binding component 3	0.018
Sorbs1	sorbin and SH3 domain containing 1	0.018
Btg1	B-cell translocation gene 1, anti-proliferative	0.018
Bach1	BTB and CNC homology 1	0.018
Xirp1	xin actin-binding repeat containing 1	0.018
Rragd	Ras-related GTP binding D	0.018
Hlf	hepatic leukemia factor	0.018
Nos1	nitric oxide synthase 1, neuronal	0.018
Pnpla2	patatin-like phospholipase domain containing 2	0.017
Lyst	lysosomal trafficking regulator	0.017
Ikzf3	IKAROS family zinc finger 3	0.017
Cacna1h	calcium channel, voltage-dependent, T type, alpha 1H subunit	0.017
Ccnd1	cyclin D1	0.016
Kit	kit oncogene	0.016
Pfn1	profilin 1	0.016
Nr1d2	nuclear receptor subfamily 1, group D, member 2	0.016
Rabgef1	RAB guanine nucleotide exchange factor (GEF) 1	0.016
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.016
Fgf13	fibroblast growth factor 13	0.016
Shank2	SH3/ankyrin domain gene 2	0.016
Cacng6	calcium channel, voltage-dependent, gamma subunit 6	0.016
Tnnc1	troponin C, cardiac/slow skeletal	0.016
Tob2	transducer of ERBB2, 2	0.015
Nsf	N-ethylmaleimide sensitive fusion protein	0.015
Grik4	glutamate receptor, ionotropic, kainate 4	0.015
Prkca	protein kinase C, alpha	0.015
Bsn	bassoon	0.015
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.015
Bhlhe41	basic helix-loop-helix family, member e41	0.015
Grm1	glutamate receptor, metabotropic 1	0.014
Bid	BH3 interacting domain death agonist	0.014
Fbxl3	F-box and leucine-rich repeat protein 3	0.014
Thbs1	thrombospondin 1	0.014
Rims4	regulating synaptic membrane exocytosis 4	0.014
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.014
Cd36	CD36 antigen	0.014
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.014
Tubb3	tubulin, beta 3	0.013
Tnnt3	troponin T3, skeletal, fast	0.013
Lmo7	LIM domain only 7	0.013
Smad1	MAD homolog 1 (Drosophila)	0.013
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.013
Map2k3	mitogen-activated protein kinase kinase 3	0.013	Rat
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.013
Sos2	son of sevenless homolog 2 (Drosophila)	0.013
Kndc1	kinase non-catalytic C-lobe domain (KIND) containing 1	0.013
Klf4	Kruppel-like factor 4 (gut)	0.013
Arhgap32	Rho GTPase activating protein 32	0.012
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.012
Samd8	sterile alpha motif domain containing 8	0.012
Cit	citron	0.012
Mafg	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)	0.012
Eea1	early endosome antigen 1	0.012
Gcap14	granule cell antiserum positive 14	0.012
Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit	0.012
Ndrg4	N-myc downstream regulated gene 4	0.012
Eno2	enolase 2, gamma neuronal	0.012
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.012
Hcrtr1	hypocretin (orexin) receptor 1	0.012
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.012
Srxn1	sulfiredoxin 1 homolog (S. cerevisiae)	0.011
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.011
Plin4	perilipin 4	0.011
Src	Rous sarcoma oncogene	0.011
Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform	0.011
Apoe	apolipoprotein E	0.011
Kif1a	kinesin family member 1A	0.011
Ell2	elongation factor RNA polymerase II 2	0.011
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.011
Aicda	activation-induced cytidine deaminase	0.011
Zyx	zyxin	0.011
Adipor1	adiponectin receptor 1	0.011
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.011
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.011
Midn	midnolin	0.011
Krt13	keratin 13	0.011
Phkg1	phosphorylase kinase gamma 1	0.011
Grn	granulin	0.011
Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta	0.011
1810013L24Rik	RIKEN cDNA 1810013L24 gene	0.010
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.010
Tcea2	transcription elongation factor A (SII), 2	0.010
Mef2a	myocyte enhancer factor 2A	0.010
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.010
Ypel5	yippee-like 5 (Drosophila)	0.010
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.010